Alexander S S Dömling (Alexander Dömling, Alexander Domling)

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 68

Top Topics

Multidrug Resistant

Plasmodium Falciparum

Molecular Docking

Top Venues

The Journal of organic chemistry

Organic letters

Angewandte Chemie (International ed. in English)

ACS combinatorial science

This page only lists publications with an associated author ORCID identifier.

Publications

Shamma Almuraikhy, Najeha Rizwana Anwardeen, Asmma Doudin, Maha Sellami, Alexander S S Dömling, Abdelali Agouni, Asmaa A Althani, Mohamed A Elrayess
Antioxidative Stress Metabolic Pathways in Moderately Active Individuals. Metabolites 13 (9) (2023)
Pravin Patil, Qiang Zheng, Katarzyna Kurpiewsk, Alexander S S Dömling
The isocyanide S N 2 reaction. Nature communications 14 (1) (2023)
Li Gao, Shabnam Shaabani, Atilio Reyes Romero, Ruixue Xu, Maryam Ahmadianmoghaddam, Alexander S S Dömling
'Chemistry at the speed of sound': automated 1536-well nanoscale synthesis of 16 scaffolds in parallel. Green chemistry : an international journal and green chemistry resource : GC 25 (4) (2023)
Shamma Almuraikhy, Najeha Rizwana Anwardeen, Asmma Doudin, Maha Sellami, Alexander S S Dömling, Abdelali Agouni, Asmaa A Al Thani, Mohamed A Elrayess
The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals. International journal of molecular sciences 24 (9) (2023)
Marta A Ważyńska, Roberto Butera, Marta Requesens, Annechien Plat, Tryfon Zarganes-Tzitzikas, Constantinos G Neochoritis, Jacek Plewka, Lukasz Skalniak, Justyna Kocik-Krol, Bogdan Musielak, Katarzyna Magiera-Mularz, Ismael Rodriguez, Simon N Blok, Marco de Bruyn, Hans W Nijman, Philip H Elsinga, Tad A Holak, Alexander S S Dömling
Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors. Journal of medicinal chemistry (2023)
Li Gao, Shabnam Shaabani, Atilio Reyes Romero, Ruixue Xu, Maryam Ahmadianmoghaddam, Alexander S S Dömling
'Chemistry at the speed of sound': automated 1536-well nanoscale synthesis of 16 scaffolds in parallel. Green chemistry : an international journal and green chemistry resource : GC 25 (4) (2023)
Pravin Patil, Qiang Zheng, Katarzyna Kurpiewska, Alexander S S Dömling
Author Correction: The isocyanide S N 2 reaction. Nature communications 14 (1) (2023)
Xin Li, Marina Diguele Romero, Sona Tcaturian, Katarzyna Kurpiewska, Alexander S S Dömling
N -Edited Guanine Isosteres. The Journal of organic chemistry (2023)
Shamma Almuraikhy, Najeha Rizwana Anwardeen, Asmma Doudin, Maha Sellami, Alexander S S Dömling, Abdelali Agouni, Asmaa A Al Thani, Mohamed A Elrayess
The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals. International journal of molecular sciences 24 (9) (2023)
Alexander S S Dömling
Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction? The Journal of organic chemistry (2022)
Shamma AlMuraikhy, Najeha Anwardeen, Aisha Naeem, Maha Sellami, Alexander S S Dömling, Abdelali Agouni, Mohamed A Elrayess
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals. International journal of environmental research and public health 19 (19) (2022)
Ruixue Xu, Zefeng Wang, Qiang Zheng, Pravin Patil, Alexander S S Dömling
A Bifurcated Multicomponent Synthesis Approach to Polycyclic Quinazolinones . The Journal of organic chemistry 87 (19) (2022)
Domna Iordanidou, Michael G Kallitsakis, Marina A Tzani, Dimitris I Ioannou, Tryfon Zarganes-Tzitzikas, Constantinos G Neochoritis, Alexander S S Dömling, Michael A Terzidis, Ioannis N Lykakis
Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones. Molecules (Basel, Switzerland) 27 (14) (2022)
Xin Li, Qian Wang, Qiang Zheng, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Access to Isoquinolin-2(1 H )-yl-acetamides and Isoindolin-2-yl-acetamides from a Common MCR Precursor. The Journal of organic chemistry 87 (21) (2022)
Eman Abdelraheem, Max Lubberink, Wenja Wang, Jingyao Li, Atilio Reyes Romero, Robin van der Straat, Xiaochen Du, Matthew R Groves, Alexander S S Dömling
Multicomponent Macrocyclic IL-17a Modifier. ACS medicinal chemistry letters 13 (9) (2022)
Chao Wang, Bidong Zhang, Arne Krüger, Xiaochen Du, Lidia Visser, Alexander S S Dömling, Carsten Wrenger, Matthew R Groves
Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. Journal of the American Chemical Society 144 (41) (2022)
Bidong Zhang, Katarzyna Kurpiewska, Alexander S S Dömling
Highly Stereoselective Ugi/Pictet-Spengler Sequence. The Journal of organic chemistry 87 (11) (2022)
Shabnam Shaabani, Louis Gadina, Ewa Surmiak, Zefeng Wang, Bidong Zhang, Roberto Butera, Tryfon Zarganes-Tzitzikas, Ismael Rodriguez, Justyna Kocik-Krol, Katarzyna Magiera-Mularz, Łukasz Skalniak, Alexander S S Dömling, Tad A Holak
Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. Molecules (Basel, Switzerland) 27 (11) (2022)
Afsaneh Sadremomtaz, Zayana M Al-Dahmani, Angel J Ruiz-Moreno, Alessandra Monti, Chao Wang, Taha Azad, John C Bell, Nunzianna Doti, Marco Antonio Velasco Velazquez, Debora de Jong, Jørgen de Jonge, Jolanda M Smit, Alexander S S Dömling, Harry van Goor, Matthew R Groves
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein. Journal of medicinal chemistry (2021)
Atilio Reyes Romero, Angel Jonathan Ruiz-Moreno, Matthew R Groves, Marco Velasco-Velázquez, Alexander S S Dömling
Correction to "Benchmark of Generic Shapes for Macrocycles". Journal of chemical information and modeling 61 (6) (2021)
Damian Muszak, Ewa Surmiak, Jacek Plewka, Katarzyna Magiera-Mularz, Justyna Kocik-Krol, Bogdan M Musielak, Dominik Sala, Radoslaw Kitel, Malgorzata Stec, Kazimierz Weglarczyk, Maciej Siedlar, Alexander S S Dömling, Łukasz Skalniak, Tad A Holak
Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction. Journal of medicinal chemistry 64 (15) (2021)
Gonçalo S Clemente, Inês F Antunes, Jürgen W A Sijbesma, Aren van Waarde, Adriaan A Lammertsma, Alexander S S Dömling, Philip H Elsinga
[18F]Atorvastatin Pharmacokinetics and Biodistribution in Healthy Female and Male Rats. Molecular pharmaceutics 18 (9) (2021)
Atilio Reyes Romero, Serjey Lunev, Grzegorz M Popowicz, Vito Calderone, Matteo Gentili, Michael Sattler, Jacek Plewka, Michał Taube, Maciej Kozak, Tad A Holak, Alexander S S Dömling, Matthew R Groves
A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity. Communications biology 4 (1) (2021)
Xiaofang Lei, Panagiota Lampiri, Pravin Patil, Giasemi K Angeli, Constantinos G Neochoritis, Alexander S S Dömling
A multicomponent tetrazolo indole synthesis. Chemical communications (Cambridge, England) 57 (54) (2021)
Kai Gao, Shabnam Shaabani, Ruixue Xu, Tryfon Zarganes-Tzitzikas, Li Gao, Maryam Ahmadianmoghaddam, Matthew R Groves, Alexander S S Dömling
Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers. RSC medicinal chemistry 12 (5) (2021)
Fandi Sutanto, Shabnam Shaabani, Rick Oerlemans, Deniz Eris, Pravin Patil, Mojgan Hadian, Meitian Wang, May Elizabeth Sharpe, Matthew R Groves, Alexander S S Dömling
Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification. Angewandte Chemie (International ed. in English) 60 (33) (2021)
Fandi Sutanto, Shabnam Shaabani, Constantinos G Neochoritis, Tryfon Zarganes-Tzitzikas, Pravin Patil, Ehsan Ghonchepour, Alexander S S Dömling
Multicomponent reaction-derived covalent inhibitor space. Science advances 7 (6) (2021)
Roberto Butera, Marta Ważyńska, Katarzyna Magiera-Mularz, Jacek Plewka, Bogdan M Musielak, Ewa Surmiak, Dominik Sala, Radoslaw Kitel, Marco de Bruyn, Hans W Nijman, Philip H Elsinga, Tad A Holak, Alexander S S Dömling
Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists. ACS medicinal chemistry letters 12 (5) (2021)
Qian Wang, Kumchok C Mgimpatsang, Xin Li, Alexander S S Dömling
Isoquinolone-4-Carboxylic Acids by Ammonia-Ugi-4CR and Copper-Catalyzed Domino Reaction. The Journal of organic chemistry 86 (14) (2021)
Markella Konstantinidou, Francesca Magari, Fandi Sutanto, Jörg Haupenthal, Varsha R Jumde, M Yagiz Ünver, Andreas Heine, Carlos Jamie Camacho, Anna K H Hirsch, Gerhard Klebe, Alexander S S Dömling
Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach. ChemMedChem 15 (8) (2020)
Fandi Sutanto, Markella Konstantinidou, Alexander S S Dömling
Covalent inhibitors: a rational approach to drug discovery. RSC medicinal chemistry 11 (8) (2020)
Qian Wang, Angelina Osipyan, Markella Konstantinidou, Roberto Butera, Kumchok C Mgimpatsang, Svetlana V Shiskina, Alexander S S Dömling
Correction to Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles. The Journal of organic chemistry 85 (12) (2020)
Jingyao Li, Vincenzo Di Lorenzo, Pravin Patil, Angel J Ruiz-Moreno, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Marco A Velasco-Velázquez, Alexander S S Dömling
Scaffolding-Induced Property Modulation of Chemical Space. ACS combinatorial science 22 (7) (2020)
Atilio Reyes Romero, Angel Jonathan Ruiz-Moreno, Matthew R Groves, Marco Velasco-Velázquez, Alexander S S Dömling
Benchmark of Generic Shapes for Macrocycles. Journal of chemical information and modeling 60 (12) (2020)
Rick Oerlemans, Angel Jonathan Ruiz-Moreno, Yingying Cong, Nilima Dinesh Kumar, Marco A Velasco-Velazquez, Constantinos G Neochoritis, Jolanda Smith, Fulvio Reggiori, Matthew R Groves, Alexander S S Dömling
Repurposing the HCV NS3-4A protease drug boceprevir as COVID-19 therapeutics. RSC medicinal chemistry 12 (3) (2020)
Qian Wang, Jesse Tuinhof, Kumchok C Mgimpatsang, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Copper-Catalyzed Modular Assembly of Polyheterocycles. The Journal of organic chemistry 85 (15) (2020)
Thimmalapura M Vishwanatha, Ben N G Giepmans, Sayed K Goda, Alexander S S Dömling
Tubulysin Synthesis Featuring Stereoselective Catalysis and Highly Convergent Multicomponent Assembly. Organic letters 22 (14) (2020)
Manuel G Ricardo, Ameena M Ali, Jacek Plewka, Ewa Surmiak, Beata Labuzek, Constantinos G Neochoritis, Jack Atmaj, Lukasz Skalniak, Ran Zhang, Tad A Holak, Matthew Groves, Daniel G Rivera, Alexander S S Dömling
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions. Angewandte Chemie (International ed. in English) 59 (13) (2020)
Angelina Osipyan, Shabnam Shaabani, Robert Warmerdam, Svitlana V Shishkina, Harry Boltz, Alexander S S Dömling
Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines. Angewandte Chemie (International ed. in English) 59 (30) (2020)
Soraya S Bosch, Sergey Lunev, Fernando A Batista, Marleen Linzke, Thales Kronenberger, Alexander S S Dömling, Matthew R Groves, Carsten Wrenger
Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2. ACS infectious diseases 6 (5) (2020)
Ramon van der Vlag, M Yagiz Unver, Tommaso Felicetti, Aleksandra Twarda-Clapa, Fatima Kassim, Cagdas Ermis, Constantinos G Neochoritis, Bogdan M Musielak, Beata Labuzek, Alexander S S Dömling, Tad A Holak, Anna Katharina Herta Hirsch
Optimized Inhibitors of MDM2 via an Attempted Protein-Templated Reductive Amination. ChemMedChem 15 (4) (2019)
Verena B K Kunig, Christiane Ehrt, Alexander S S Dömling, Andreas Brunschweiger
Isocyanide Multicomponent Reactions on Solid-Phase-Coupled DNA Oligonucleotides for Encoded Library Synthesis. Organic letters 21 (18) (2019)
Qian Wang, Kumchok C Mgimpatsang, Markella Konstantinidou, Svitlana V Shishkina, Alexander S S Dömling
1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction. Organic letters 21 (18) (2019)
Yuanze Wang, Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Diverse Isoquinoline Scaffolds by Ugi/Pomeranz-Fritsch and Ugi/Schlittler-Müller Reactions. Organic letters 21 (10) (2019)
Qian Wang, Angelina Osipyan, Markella Konstantinidou, Roberto Butera, Kumchok C Mgimpatsang, Svetlana V Shiskina, Alexander S S Dömling
Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles. The Journal of organic chemistry 84 (18) (2019)
Constantinos G Neochoritis, Shabnam Shaabani, Maryam Ahmadianmoghaddam, Tryfon Zarganes-Tzitzikas, Li Gao, Michaela Novotná, Tatiana Mitríková, Atilio Reyes Romero, Marina Ika Irianti, Ruixue Xu, Joe Olechno, Richard Ellson, Victoria Helan, Michael Kossenjans, Matthew R Groves, Alexander S S Dömling
Rapid approach to complex boronic acids. Science advances 5 (7) (2019)
Fernando de Assis Batista, Soraya S Bosch, Sabine Butzloff, Sergey Lunev, Kamila A Meissner, Marleen Linzke, Atilio R Romero, Chao Wang, Ingrid B Müller, Alexander S S Dömling, Matthew R Groves, Carsten Wrenger
Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum. MicrobiologyOpen (2019)
Constantinos G Neochoritis, Ting Zhao, Alexander S S Dömling
Tetrazoles via Multicomponent Reactions. Chemical reviews 119 (3) (2019)
Santosh Kurhade, Elmar Diekstra, Fandi Sutanto, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines. Organic letters 20 (13) (2018)
Pravin Patil, Bhupendra Mishra, Gitanjali Sheombarsing, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Library-to-Library Synthesis of Highly Substituted α-Aminomethyl Tetrazoles via Ugi Reaction. ACS combinatorial science 20 (2) (2018)
Eman M M Abdelraheem, Samad Khaksar, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Shabnam Shaabani, Alexander S S Dömling
Two-Step Macrocycle Synthesis by Classical Ugi Reaction. The Journal of organic chemistry 83 (3) (2018)
Rudrakshula Madhavachary, Qian Wang, Alexander S S Dömling
With unprotected amino acids to tetrazolo peptidomimetics. Chemical communications (Cambridge, England) 53 (61) (2018)
Shabnam Shaabani, Alexander S S Dömling
The Catalytic Enantioselective Ugi Four-Component Reactions. Angewandte Chemie (International ed. in English) 57 (50) (2018)
Markella Konstantinidou, Tryfon Zarganes-Tzitzikas, Katarzyna Magiera-Mularz, Tad A Holak, Alexander S S Dömling
Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies? Angewandte Chemie (International ed. in English) 57 (18) (2018)
Rudrakshula Madhavachary, Tryfon Zarganes-Tzitzikas, Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR. ACS combinatorial science 20 (4) (2018)
Eman M M Abdelraheem, Shabnam Shaabani, Alexander S S Dömling
Artificial Macrocycles. Synlett : accounts and rapid communications in synthetic organic chemistry 29 (9) (2018)
Ajay L Chandgude, Alexander S S Dömling
N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides. Organic letters 19 (5) (2017)
Aleksandra Twarda-Clapa, Sylwia Krzanik, Katarzyna Kubica, Katarzyna Guzik, Beata Labuzek, Constantinos G Neochoritis, Kareem Khoury, Kaja Kowalska, Miroslawa Czub, Grzegorz Dubin, Alexander S S Dömling, Łukasz Skalniak, Tad A Holak
1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers. Journal of medicinal chemistry 60 (10) (2017)
Eman M M Abdelraheem, Rudrakshula Madhavachary, Arianna Rossetti, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Shabnam Shaabani, Alexander S S Dömling
Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings. Organic letters 19 (22) (2017)
Yuanze Wang, Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations. ACS combinatorial science 19 (3) (2017)
Thimmalapura M Vishwanatha, Katarzyna Kurpiewska, Justyna Kalinowska-Tluscik, Alexander S S Dömling
Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles. The Journal of organic chemistry 82 (18) (2017)
Eman M M Abdelraheem, Michel P de Haan, Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Shabnam Shaabani, Alexander S S Dömling
Concise Synthesis of Tetrazole Macrocycle. Organic letters 19 (19) (2017)
Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander S S Dömling
Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction. ACS combinatorial science 19 (5) (2017)
Katarzyna Guzik, Krzysztof M Zak, Przemyslaw Grudnik, Katarzyna Magiera, Bogdan Musielak, Ricarda Törner, Łukasz Skalniak, Alexander S S Dömling, Grzegorz Dubin, Tad A Holak
Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. Journal of medicinal chemistry 60 (13) (2017)
Pravin Patil, Rudrakshula Madhavachary, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander S S Dömling
De Novo Assembly of Highly Substituted Morpholines and Piperazines. Organic letters 19 (3) (2017)
Thimmalapura M Vishwanatha, Enrico Bergamaschi, Alexander S S Dömling
Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics. Organic letters 19 (12) (2017)
Rudrakshula Madhavachary, Eman M M Abdelraheem, Arianna Rossetti, Aleksandra Twarda-Clapa, Bogdan Musielak, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Tad A Holak, Alexander S S Dömling
Two-Step Synthesis of Complex Artificial Macrocyclic Compounds. Angewandte Chemie (International ed. in English) 56 (36) (2017)
Ajay L Chandgude, Alexander S S Dömling
Unconventional Passerini Reaction toward α-Aminoxy-amides. Organic letters 18 (24) (2016)