Alexander L Nielsen

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 26

Top Venues

Angewandte Chemie (International ed. in English)

Nature chemical biology

International journal of molecular sciences

Journal of peptide science : an official publication of the European Peptide Society

University of Copenhagen

University of Copenhagen (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Sep 01 2017

Denmark

PhD fellow, Medicinal Chemistry :: Department of Drug Design and Pharmacology

Scripps Research Feb 17 2020 - Aug 16 2020

United States

Visiting PhD student :: Department of Chemistry

Education History

University of Copenhagen Sep 01 2015 - Aug 28 2017

Denmark

MSC

University of Copenhagen Sep 01 2011 - Jun 30 2015

Denmark

BSC

Publications

Alexander L Nielsen, Zsolt Bognár, Ganesh Kumar Mothukuri, Anne Zarda, Mischa Schüttel, Manuel Leonardo Merz, Xinjian Ji, Edward J Will, Monica Chinellato, Christian R O Bartling, Kristian Stro Mgaard, Laura Cendron, Alessandro Angelini, Christian Heinis
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation. Angewandte Chemie (International ed. in English) 63 (26) (2024)
Alexander L Nielsen, Zsolt Bognár, Ganesh Kumar Mothukuri, Anne Zarda, Mischa Schüttel, Manuel Leonardo Merz, Xinjian Ji, Edward J Will, Monica Chinellato, Christian R O Bartling, Kristian Stro Mgaard, Laura Cendron, Alessandro Angelini, Christian Heinis
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation. Angewandte Chemie (International ed. in English) (2024)
Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L Nielsen, Christian Heinis
Solid-phase peptide synthesis in 384-well plates. Journal of peptide science : an official publication of the European Peptide Society 30 (4) (2024)
Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L Nielsen, Christian Heinis
Solid-phase peptide synthesis in 384-well plates. Journal of peptide science : an official publication of the European Peptide Society 30 (4) (2024)
Alexander L Nielsen, Zsolt Bognár, Ganesh Kumar Mothukuri, Anne Zarda, Mischa Schüttel, Manuel Leonardo Merz, Xinjian Ji, Edward J Will, Monica Chinellato, Christian R O Bartling, Kristian Stro Mgaard, Laura Cendron, Alessandro Angelini, Christian Heinis
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation. Angewandte Chemie (International ed. in English) 63 (26) (2024)
Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L Nielsen, Christian Heinis
Solid-phase peptide synthesis in 384-well plates. Journal of peptide science : an official publication of the European Peptide Society (2024)
Xinjian Ji, Alexander L Nielsen, Christian Heinis
Cyclic Peptides for Drug Development. Angewandte Chemie (International ed. in English) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Manuel Leonardo Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G L David, Alexander L Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M Duany Benitez, Phoukham Phothirath, Christian Heinis
De novo development of small cyclic peptides that are orally bioavailable. Nature chemical biology 20 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Manuel Leonardo Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G L David, Alexander L Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M Duany Benitez, Phoukham Phothirath, Christian Heinis
De novo development of small cyclic peptides that are orally bioavailable. Nature chemical biology 20 (5) (2023)
Manuel Leonardo Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G L David, Alexander L Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M Duany Benitez, Phoukham Phothirath, Christian Heinis
De novo development of small cyclic peptides that are orally bioavailable. Nature chemical biology (2023)
Manuel Leonardo Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G L David, Alexander L Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M Duany Benitez, Phoukham Phothirath, Christian Heinis
De novo development of small cyclic peptides that are orally bioavailable. Nature chemical biology 20 (5) (2023)
Zsolt Bognár, Ganesh Kumar Mothukuri, Alexander L Nielsen, Manuel Leonardo Merz, Peter M F Pânzar, Christian Heinis
Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides. Organic & biomolecular chemistry 20 (29) (2022)
Nima Rajabi, Tobias N Hansen, Alexander L Nielsen, Huy T Nguyen, Michael Bæk, Julie E Bolding, Oskar Ø Bahlke, Sylvester E G Petersen, Christian R O Bartling, Kristian Stro Mgaard, Christian A Olsen
Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme. Angewandte Chemie (International ed. in English) 61 (22) (2022)
Carlos Moreno-Yruela, Di Zhang, Wei Wei, Michael Bæk, Wenchao Liu, Jinjun Gao, Daniela Danková, Alexander L Nielsen, Julie E Bolding, Lu Yang, Samuel T Jameson, Jiemin Wong, Christian A Olsen, Yingming Zhao
Class I histone deacetylases (HDAC1-3) are histone lysine delactylases. Science advances 8 (3) (2022)
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Sabine Pellett, Takashi Sugane, Margaret E Olson, Eric A Johnson, Kim D Janda
Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach. RSC medicinal chemistry 12 (6) (2021)
Kathrin S Troelsen, Michael Bæk, Alexander L Nielsen, Andreas S Madsen, Nima Rajabi, Christian A Olsen
Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase. RSC chemical biology 2 (2) (2021)
Alexander L Nielsen, Nima Rajabi, Norio Kudo, Kathrine Lundø, Carlos Moreno-Yruela, Michael Bæk, Martin Fontenas, Alessia Lucidi, Andreas S Madsen, Minoru Yoshida, Christian A Olsen
Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration. RSC chemical biology 2 (2) (2021)
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Antonio J Campedelli, Nicholas R Silvaggi, Jason S Chen, Amanda E Wakefield, Karen N Allen, Kim D Janda
Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. ACS medicinal chemistry letters 12 (8) (2021)
Lucy Lin, Margaret E Olson, Takashi Sugane, Lewis D Turner, Margarita A Tararina, Alexander L Nielsen, Elbek K Kurbanov, Sabine Pellett, Eric A Johnson, Seth M Cohen, Karen N Allen, Kim D Janda
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A. Journal of medicinal chemistry 63 (19) (2020)
Oksana Dmytriyeva, Amaia de Diego Ajenjo, Kathrine Lundø, Henrik Hertz, Kim K Rasmussen, Anders T Christiansen, Jorg Klingelhofer, Alexander L Nielsen, Jan Hoeber, Elena N Kozlova, David P D Woldbye, Stanislava Pankratova
Neurotrophic Effects of Vascular Endothelial Growth Factor B and Novel Mimetic Peptides on Neurons from the Central Nervous System. ACS chemical neuroscience 11 (9) (2020)
Alexander L Nielsen, Christian A Olsen
Finding the gas pedal on a slow sirtuin. The Journal of biological chemistry 295 (5) (2020)
Hang Zhang, Alexander L Nielsen, Kristian Stro Mgaard
Recent achievements in developing selective Gq inhibitors. Medicinal research reviews 40 (1) (2019)

Alexander L Nielsen.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Alexander L Nielsen