Benjamin N Atkinson

ORCID

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 8

Top Venues

Journal of medicinal chemistry

Beilstein journal of organic chemistry

RSC advances

ACS chemical neuroscience

University College London

University of Bath Department of Chemistry (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University College London Jan 3o 2017

United Kingdom

Research Associate :: Institute of Neurology

Education History

University of Bath Department of Chemistry Oct 3o 2011 - Oct 3o 2014

United Kingdom

PHD

Publications

Nicky J Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah L Woodward, Benjamin N Atkinson, Elliott David Bayle, Fredrik Svensson, Sarah Frew, Fiona Jeganathan, Amy Monaghan, Stefano Benvegnù, Sarah Jolly, Luca Vecchia, Reinis R Ruza, Svend Kjær, Steven Howell, Ambrosius P Snijders, Magda Bictash, Patricia C Salinas, Jean-Paul Vincent, Edith Yvonne Jones, Paul Whiting, Paul V Fish
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. Journal of medicinal chemistry 65 (10) (2022)
Yuguang Zhao, William Mahy, Nicky J Willis, Hannah L Woodward, David Steadman, Elliott D Bayle, Benjamin N Atkinson, James Sipthorp, Luca Vecchia, Reinis R Ruza, Karl Harlos, Fiona Jeganathan, Stefan Constantinou, Artur Costa, Svend Kjær, Magda Bictash, Patricia C Salinas, Paul Whiting, Jean-Paul Vincent, Paul V Fish, Edith Yvonne Jones
Structural Analysis and Development of Notum Fragment Screening Hits. ACS chemical neuroscience 13 (13) (2022)
Benjamin N Atkinson, Nicky J Willis, Jennifer Smith, Rebecca Gill, Jody Ali, Zhou Xu, Ping-Shan Lai, Paul V Fish
Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1 H -1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step. RSC advances 12 (41) (2022)
David Steadman, Benjamin N Atkinson, Yuguang Zhao, Nicky J Willis, Sarah Frew, Amy Monaghan, Chandni Patel, Emma Armstrong, Kathryn Costelloe, Lorenza Magno, Magda Bictash, Edith Yvonne Jones, Paul V Fish, Fredrik Svensson
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity. Journal of medicinal chemistry 65 (1) (2021)
William Mahy, Mikesh Patel, David Steadman, Hannah L Woodward, Benjamin N Atkinson, Fredrik Svensson, Nicky J Willis, Alister Flint, Dimitra Papatheodorou, Yuguang Zhao, Luca Vecchia, Reinis R Ruza, James Hillier, Sarah Frew, Amy Monaghan, Artur Costa, Magda Bictash, Magnus W Walter, Edith Yvonne Jones, Paul V Fish
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity. Journal of medicinal chemistry 63 (17) (2020)
Nicky J Willis, Elliott D Bayle, George Papageorgiou, David Steadman, Benjamin N Atkinson, William Mahy, Paul V Fish
An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent. Beilstein journal of organic chemistry 15 (2019)
Benjamin N Atkinson, David Steadman, Yuguang Zhao, James Sipthorp, Luca Vecchia, Reinis R Ruza, Fiona Jeganathan, Georgie Lines, Sarah Frew, Amy Monaghan, Svend Kjær, Magda Bictash, Edith Yvonne Jones, Paul V Fish
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen. MedChemComm 10 (8) (2019)
Benjamin N Atkinson, Hannah L Woodward, James Sipthorp, Paul V Fish
Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives. Organic & biomolecular chemistry 15 (46) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Benjamin N Atkinson