Byron Caughey

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Venues

PLoS pathogens

Nature chemical biology

Acta neuropathologica

Acta neuropathologica communications

This page only lists publications with an associated author ORCID identifier.

Publications

Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P J Knowles, Christopher M Dobson
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning. Nature chemical biology 20 (5) (2024)
Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P J Knowles, Christopher M Dobson
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning. Nature chemical biology 20 (5) (2024)
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces. PLoS pathogens 20 (4) (2024)
Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P J Knowles, Christopher M Dobson
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning. Nature chemical biology 20 (5) (2024)
Ankit Srivastava, Qinlu Wang, Christina D Orrù, Manel Fernandez, Yaroslau Compta, Bernardino Ghetti, Gianluigi Zanusso, Wen-Quan Zou, Byron Caughey, Catherine A A Beauchemin
Enhanced quantitation of pathological α-synuclein in patient biospecimens by RT-QuIC seed amplification assays. PLoS pathogens 20 (9) (2024)
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces. PLoS pathogens 20 (4) (2024)
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces. PLoS pathogens 20 (4) (2024)
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces. PLoS pathogens 20 (4) (2024)
Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P J Knowles, Christopher M Dobson
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning. Nature chemical biology 20 (5) (2024)
Robert I Horne, Ewa A Andrzejewska, Parvez Alam, Z Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P J Knowles, Christopher M Dobson
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning. Nature chemical biology (2024)
Forrest Hoyt, Parvez Alam, Efrosini Artikis, Cindi L Schwartz, Andrew G Hughson, Brent Race, Chase Baune, Gregory J Raymond, Gerald S Baron, Allison Kraus, Byron Caughey
Cryo-EM of prion strains from the same genotype of host identifies conformational determinants. PLoS pathogens 18 (11) (2022)
Forrest H Hoyt, Heidi G Standke, Efrosini Artikis, Cindi L Schwartz, Bryan Hansen, Kunpeng Li, Andrew G Hughson, Matteo Manca, Olivia R Thomas, Gregory J Raymond, Brent Race, Gerald S Baron, Byron Caughey, Allison Kraus
Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains. Nature communications 13 (1) (2022)
Byron Caughey, Heidi G Standke, Efrosini Artikis, Forrest Hoyt, Allison Kraus
Pathogenic prion structures at high resolution. PLoS pathogens 18 (6) (2022)
Christina D Orrú, Bradley R Groveman, Aaron Foutz, Matilde Bongianni, Franco Cardone, Neil McKenzie, Audrey Culeux, Anna Poleggi, Katarina Grznarova, Daniela Perra, Michele Fiorini, Xiaoqin Liu, Anna Ladogana, Marco Sbriccoli, Andrew G Hughson, Stéphane Haïk, Alison J Green, Michael D Geschwind, Maurizio Pocchiari, Jiri G Safar, Gianluigi Zanusso, Byron Caughey
Ring trial of 2nd generation RT-QuIC diagnostic tests for sporadic CJD. Annals of clinical and translational neurology 7 (11) (2021)
Bradley R Groveman, Christina D Orrù, Andrew G Hughson, Lynne D Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J Campbell, Jiri Safar, Douglas Galasko, Byron Caughey
Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. Acta neuropathologica communications 8 (1) (2020)
Christina D Orrú, Thong C Ma, Andrew G Hughson, Bradley R Groveman, Ankit Srivastava, Douglas Galasko, Rachel Angers, Patrick Downey, Karen Crawford, Samantha J Hutten, Un Jung Kang, Byron Caughey
A rapid α-synuclein seed assay of Parkinson's disease CSF panel shows high diagnostic accuracy. Annals of clinical and translational neurology 8 (2) (2020)
Efrosini Artikis, Amitava Roy, Hugo Verli, Yraima Cordeiro, Byron Caughey
Accommodation of In-Register N-Linked Glycans on Prion Protein Amyloid Cores. ACS chemical neuroscience 11 (24) (2020)
Gregory J Raymond, Brent Race, Christina D Orrú, Lynne D Raymond, Matilde Bongianni, Michele Fiorini, Bradley R Groveman, Sergio Ferrari, Luca Sacchetto, Andrew G Hughson, Salvatore Monaco, Maurizio Pocchiari, Gianluigi Zanusso, Byron Caughey
Transmission of CJD from nasal brushings but not spinal fluid or RT-QuIC product. Annals of clinical and translational neurology 7 (6) (2020)
Michael A Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases. Acta neuropathologica communications 8 (1) (2020)
Alessandra Favole, Maria Mazza, Elena Vallino Costassa, Antonio D'Angelo, Guerino Lombardi, Paola Marconi, Paola Crociara, Elena Berrone, Marina Gallo, Claudia Palmitessa, Christina D Orrù, Byron Caughey, Pier L Acutis, Maria Caramelli, Cristina Casalone, Cristiano Corona
Early and Pre-Clinical Detection of Prion Seeding Activity in Cerebrospinal Fluid of Goats using Real-Time Quaking-Induced Conversion Assay. Scientific reports 9 (1) (2019)
Eri Saijo, Michael A Metrick, Shunsuke Koga, Piero Parchi, Irene Litvan, Salvatore Spina, Adam Boxer, Julio C Rojas, Douglas Galasko, Allison Kraus, Marcello Rossi, Kathy Newell, Gianluigi Zanusso, Lea T Grinberg, William W Seeley, Bernardino Ghetti, Dennis W Dickson, Byron Caughey
4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta neuropathologica 139 (1) (2019)
Zerui Wang, Matteo Manca, Aaron Foutz, Manuel V Camacho, Gregory J Raymond, Brent Race, Christina D Orru, Jue Yuan, Pingping Shen, Baiya Li, Yue Lang, Johnny Dang, Alise Adornato, Katie Williams, Nicholas R Maurer, Pierluigi Gambetti, Bin Xu, Witold Surewicz, Robert B Petersen, Xiaoping Dong, Brian S Appleby, Byron Caughey, Li Cui, Qingzhong Kong, Wen-Quan Zou
Early preclinical detection of prions in the skin of prion-infected animals. Nature communications 10 (1) (2019)
Michael A Metrick, Natalia do Carmo Ferreira, Eri Saijo, Andrew G Hughson, Allison Kraus, Christina Orrú, Michael W Miller, Gianluigi Zanusso, Bernardino Ghetti, Christopher M Dobson, Byron Caughey
Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons. Proceedings of the National Academy of Sciences of the United States of America 116 (46) (2019)
Zerui Wang, Matteo Manca, Aaron Foutz, Manuel V Camacho, Gregory J Raymond, Brent Race, Christina D Orru, Jue Yuan, Pingping Shen, Baiya Li, Yue Lang, Johnny Dang, Alise Adornato, Katie Williams, Nicholas R Maurer, Pierluigi Gambetti, Bin Xu, Witold Surewicz, Robert B Petersen, Xiaoping Dong, Brian S Appleby, Byron Caughey, Li Cui, Qingzhong Kong, Wen-Quan Zou
Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals. Nature communications 10 (1) (2019)
Christina D Orrú, Jue Yuan, Brian S Appleby, Baiya Li, Yu Li, Dane Winner, Zerui Wang, Yi-An Zhan, Mark Rodgers, Jason Rarick, Robert E Wyza, Tripti Joshi, Gong-Xian Wang, Mark L Cohen, Shulin Zhang, Bradley R Groveman, Robert B Petersen, James W Ironside, Miguel E Quiñones-Mateu, Jiri G Safar, Qingzhong Kong, Byron Caughey, Wen-Quan Zou
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease. Science translational medicine 9 (417) (2018)
Bradley R Groveman, Christina D Orrù, Andrew G Hughson, Lynne D Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J Campbell, Jiri Safar, Douglas Galasko, Byron Caughey
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. Acta neuropathologica communications 6 (1) (2018)
Allison Kraus, Eri Saijo, Michael A Metrick, Kathy Newell, Christina J Sigurdson, Gianluigi Zanusso, Bernardino Ghetti, Byron Caughey
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease. Acta neuropathologica 137 (4) (2018)
Fei Wang, Xinhe Wang, Christina D Orrú, Bradley R Groveman, Krystyna Surewicz, Romany Abskharon, Morikazu Imamura, Takashi Yokoyama, Yong-Sun Kim, Kayla J Vander Stel, Kumar Sinniah, Suzette A Priola, Witold K Surewicz, Byron Caughey, Jiyan Ma
Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity. PLoS pathogens 13 (7) (2017)
Eri Saijo, Bernardino Ghetti, Gianluigi Zanusso, Adrian Oblak, Jennifer L Furman, Marc I Diamond, Allison Kraus, Byron Caughey
Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid. Acta neuropathologica 133 (5) (2017)
Matthias Schmitz, Maria Cramm, Franc Llorens, Dominik Müller-Cramm, Steven Collins, Ryuichiro Atarashi, Katsuya Satoh, Christina D Orrù, Bradley R Groveman, Saima Zafar, Walter J Schulz-Schaeffer, Byron Caughey, Inga Zerr
The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases. Nature protocols 11 (11) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Byron Caughey