C David Owen

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 15

Top Topics

Trypanosoma Cruzi

Mass Spectrometry

Respiratory Syndrome Coronavirus

Top Venues

Journal of medicinal chemistry

ACS central science

Science advances

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Paul Benjamin Klar, David Geoffrey Waterman, Tim Gruene, Debakshi Mullick, Yun Song, James Boris Gilchrist, C David Owen, Wen Wen, Idan Biran, Lothar Houben, Neta Regev-Rudzki, Ron Dzikowski, Noa Marom, Lukáš Palatinus, Peijun Zhang, Leslie Leiserowitz, Michael Elbaum
Cryo-tomography and 3D Electron Diffraction Reveal the Polar Habit and Chiral Structure of the Malaria Pigment Crystal Hemozoin. ACS central science 10 (8) (2024)
Paul Benjamin Klar, David Geoffrey Waterman, Tim Gruene, Debakshi Mullick, Yun Song, James Boris Gilchrist, C David Owen, Wen Wen, Idan Biran, Lothar Houben, Neta Regev-Rudzki, Ron Dzikowski, Noa Marom, Lukáš Palatinus, Peijun Zhang, Leslie Leiserowitz, Michael Elbaum
Cryo-tomography and 3D Electron Diffraction Reveal the Polar Habit and Chiral Structure of the Malaria Pigment Crystal Hemozoin. ACS central science 10 (8) (2024)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Vijil Chenthamarakshan, Samuel C Hoffman, C David Owen, Petra Lukacik, Claire Strain-Damerell, Daren Fearon, Tika R Malla, Anthony Tumber, Christopher J Schofield, Helen M E Duyvesteyn, Wanwisa Dejnirattisai, Loic Carrique, Thomas S Walter, Gavin R Screaton, Tetiana Matviiuk, Aleksandra Mojsilovic, Jason Crain, Martin Austin Walsh, David I Stuart, Payel Das
Accelerating drug target inhibitor discovery with a deep generative foundation model. Science advances 9 (25) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Luiz Carlos Saramago, Marcos V Santana, Bárbara Figueira Gomes, Rafael Ferreira Dantas, Mario R Senger, Pedro Henrique Oliveira Borges, Vivian Neuza Dos Santos Ferreira, Alice Dos Santos Rosa, Amanda Resende Tucci, Milene Dias Miranda, Petra Lukacik, Claire Strain-Damerell, C David Owen, Martin Austin Walsh, Sabrina Baptista Ferreira, Floriano Paes Silva-Jr
AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro . Journal of chemical information and modeling (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Tika R Malla, Lennart Brewitz, Dorian-Gabriel Muntean, Hiba Aslam, C David Owen, Eidarus Salah, Anthony Tumber, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin A Walsh, Christopher J Schofield
Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine. Journal of medicinal chemistry 65 (11) (2022)
Tika R Malla, Anthony Tumber, Tobias John, Lennart Brewitz, Claire Strain-Damerell, C David Owen, Petra Lukacik, H T Henry Chan, Pratheesh Maheswaran, Eidarus Salah, Fernanda Duarte, Haitao Yang, Zihe Rao, Martin Austin Walsh, Christopher J Schofield
Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mpro inhibitors. Chemical communications (Cambridge, England) 57 (12) (2021)
H T Henry Chan, Marc A Moesser, Rebecca K Walters, Tika R Malla, Rebecca M Twidale, Tobias John, Helen M Deeks, Tristan Johnston-Wood, Victor Mikhailov, Richard B Sessions, William Dawson, Eidarus Salah, Petra Lukacik, Claire Strain-Damerell, C David Owen, Takahito Nakajima, Katarzyna Świderek, Alessio Lodola, Vicent Moliner, David R Glowacki, James Spencer, Martin Austin Walsh, Christopher J Schofield, Luigi Genovese, Deborah K Shoemark, Adrian J Mulholland, Fernanda Duarte, Garrett M Morris
Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding. Chemical science 12 (41) (2021)