Martin Austin Walsh (Martin Walsh, Martin A Walsh)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 29

Top Venues

Journal of medicinal chemistry

Communications chemistry

bioRxiv : the preprint server for biology

RSC chemical biology

Diamond Light Source Ltd

National University of Ireland (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Diamond Light Source Ltd Jan 01 2009

United Kingdom

Deputy Director Life Sciences :: Life Sciences

MRC France May 01 2001 - Dec 31 2009

France

Group Leader :: BM14

Istituto di Ricerche di Biologia Molecolare Jan 01 2000 - Apr 30 2001

Italy

Senior Research Scientist :: Biochemistry

Istituto di Ricerche di Biologia Molecolare Jan 15 1999 - Jan 01 2000

Italy

Research Scientist :: Biochemistry

Argonne National Laboratory Mar 01 1997 - Jan 15 1999

United States

Post Doctoral Research Fellow :: Biosciences

EMBL Hamburg Mar 01 1995 - Feb 28 1997

Germany

EU Post Doctoral Research Fellow :: Protein Crystallography

University of York May 01 1994 - Feb 28 1995

United Kingdom

Post Doctoral Research Fellow :: Chemistry

EMBL Hamburg Jun 01 1994 - Oct 31 1994

Germany

EMBL short-term visiting scientist :: Protein Crystallography

Education History

National University of Ireland Sep 01 1989 - Mar 31 1994

Ireland

PHD :: Chemistry

National University of Ireland Sep 01 1985 - Jun 01 1989

Ireland

BSC :: chemistry

Publications

Ana Martínez Gascueña, Haiyang Wu, Rui Wang, C David Owen, Pedro J Hernando, Serena Monaco, Matthew Penner, Ke Xing, Gwenaelle Le Gall, Richard A Gardner, Didier Ndeh, Paulina A Urbanowicz, Daniel I R Spencer, Martin Austin Walsh, Jesus Angulo, Nathalie Juge
Exploring the sequence-function space of microbial fucosidases. Communications chemistry 7 (1) (2024)
Ana Martínez Gascueña, Haiyang Wu, Rui Wang, C David Owen, Pedro J Hernando, Serena Monaco, Matthew Penner, Ke Xing, Gwenaelle Le Gall, Richard A Gardner, Didier Ndeh, Paulina A Urbanowicz, Daniel I R Spencer, Martin Austin Walsh, Jesus Angulo, Nathalie Juge
Exploring the sequence-function space of microbial fucosidases. Communications chemistry 7 (1) (2024)
Peter J Harrison, Charles W E Tomlinson, Michael Fairhead, Max Winokan, Warren A Thompson, Conor Wild, Jasmin Cara Aschenbrenner, Blake H Balcomb, Peter George Marples, Anu V Chandran, Mathew Golding, Lizbé Koekemoer, Eleanor P Williams, SiYl Wang, Xiaomin Ni, Elizabeth MacLean, Charline Giroud, Andre Schutzer Godoy, Mary-Ann Elvina Xavier, Martin Austin Walsh, Daren Fearon, Frank von Delft
Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals. bioRxiv : the preprint server for biology (2024)
Ana Martínez Gascueña, Haiyang Wu, Rui Wang, C David Owen, Pedro J Hernando, Serena Monaco, Matthew Penner, Ke Xing, Gwenaelle Le Gall, Richard A Gardner, Didier Ndeh, Paulina A Urbanowicz, Daniel I R Spencer, Martin Austin Walsh, Jesus Angulo, Nathalie Juge
Exploring the sequence-function space of microbial fucosidases. Communications chemistry 7 (1) (2024)
Andre Schutzer Godoy, Nathalya C M R Mesquita, Gabriela Dias Noske, Victor Oliveira Gawriljuk, Peter J Harrison, Blake H Balcomb, Jasmin Cara Aschenbrenner, Charles W E Tomlinson, Max Winokan, Jenke Scheen, Peter George Marples, Anu V Chandran, Xiaomin Ni, Warren A Thompson, Michael Fairhead, Daren Fearon, Lizbé Koekemoer, Mary-Ann Elvina Xavier, Martin Austin Walsh, Glaucius Oliva, Frank von Delft
High-throughput crystallographic fragment screening of Zika virus NS3 Helicase. bioRxiv : the preprint server for biology (2024)
Charlotte Cordery, Jack Craddock, Martin Malý, Kieran Basavaraja, Jeremy S Webb, Martin Austin Walsh, Ivo Tews
Control of phosphodiesterase activity in the regulator of biofilm dispersal RbdA from Pseudomonas aeruginosa . RSC chemical biology (2024)
Andre Schutzer Godoy, Nathalya C M R Mesquita, Gabriela Dias Noske, Victor Oliveira Gawriljuk, Peter J Harrison, Blake H Balcomb, Jasmin Cara Aschenbrenner, Charles W E Tomlinson, Max Winokan, Jenke Scheen, Peter George Marples, Anu V Chandran, Xiaomin Ni, Warren A Thompson, Michael Fairhead, Daren Fearon, Lizbé Koekemoer, Mary-Ann Elvina Xavier, Martin Austin Walsh, Glaucius Oliva, Frank von Delft
High-throughput crystallographic fragment screening of Zika virus NS3 Helicase. bioRxiv : the preprint server for biology (2024)
Xiaomin Ni, Andre Schutzer Godoy, Peter George Marples, Michael Fairhead, Blake H Balcomb, Matteo P Ferla, Charles W E Tomlinson, Siyi Wang, Charline Giroud, Jasmin Cara Aschenbrenner, Peter J Harrison, Max Winokan, Anu V Chandran, Warren A Thompson, Mary-Ann Elvina Xavier, Eleanor P Williams, Martin Austin Walsh, Daren Fearon, Lizbé Koekemoer, Frank von Delft
Crystallographic fragment screening delivers diverse chemical scaffolds for Zika virus NS2B-NS3 protease inhibitor development. bioRxiv : the preprint server for biology (2024)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
H T Henry Chan, Lennart Brewitz, Petra Lukacik, Claire Strain-Damerell, Martin Austin Walsh, Christopher J Schofield, Fernanda Duarte
Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein. RSC chemical biology 5 (2) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Vijil Chenthamarakshan, Samuel C Hoffman, C David Owen, Petra Lukacik, Claire Strain-Damerell, Daren Fearon, Tika R Malla, Anthony Tumber, Christopher J Schofield, Helen M E Duyvesteyn, Wanwisa Dejnirattisai, Loic Carrique, Thomas S Walter, Gavin R Screaton, Tetiana Matviiuk, Aleksandra Mojsilovic, Jason Crain, Martin Austin Walsh, David I Stuart, Payel Das
Accelerating drug target inhibitor discovery with a deep generative foundation model. Science advances 9 (25) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Luiz Carlos Saramago, Marcos V Santana, Bárbara Figueira Gomes, Rafael Ferreira Dantas, Mario R Senger, Pedro Henrique Oliveira Borges, Vivian Neuza Dos Santos Ferreira, Alice Dos Santos Rosa, Amanda Resende Tucci, Milene Dias Miranda, Petra Lukacik, Claire Strain-Damerell, C David Owen, Martin Austin Walsh, Sabrina Baptista Ferreira, Floriano Paes Silva-Jr
AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro . Journal of chemical information and modeling (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry (2023)
Kamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, Christian M Orr, Merlyn Latimer-Smith, Graeme Winter, Vinay Grama, Feng Qu, Kiran Bountra, Hok Sau Kwong, Maria Romano, Rosana I Reis, Lutz Vogeley, Luca Vecchia, C David Owen, Sina Wittmann, Max Renner, Miki Senda, Naohiro Matsugaki, Yoshiaki Kawano, Thomas A Bowden, Isabel Moraes, Jonathan M Grimes, Erika J Mancini, Martin Austin Walsh, Cristiane Rodrigues Guzzo Carvalho, Raymond J Owens, E Yvonne Jones, David G Brown, David I Stuart, Konstantinos Beis, Armin Wagner
Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Communications chemistry 6 (1) (2023)
H T Henry Chan, Lennart Brewitz, Petra Lukacik, Claire Strain-Damerell, Martin Austin Walsh, Christopher J Schofield, Fernanda Duarte
Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein. RSC chemical biology 5 (2) (2023)
Takashi Miura, Tika R Malla, C David Owen, Anthony Tumber, Lennart Brewitz, Michael A McDonough, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin Austin Walsh, Akane Kawamura, Christopher J Schofield, Hiroaki Suga
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ 2,4 -amino acids targeting the SARS-CoV-2 main protease. Nature chemistry (2023)
Lennart Brewitz, Leo Dumjahn, Yilin Zhao, C David Owen, Stephen M Laidlaw, Tika R Malla, Dung Nguyen, Petra Lukacik, Eidarus Salah, Adam D Crawshaw, Anna J Warren, Jose Trincao, Claire Strain-Damerell, Miles W Carroll, Martin Austin Walsh, Christopher J Schofield
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine. Journal of medicinal chemistry 66 (4) (2023)
Richard J Gildea, James Beilsten-Edmands, Danny N Axford, Sam Horrell, Pierre Aller, James Sandy, Juan Sanchez-Weatherby, C David Owen, Petra Lukacik, Claire Strain-Damerell, Robin L Owen, Martin Austin Walsh, Graeme Winter
xia2.multiplex: a multi-crystal data-analysis pipeline. Acta crystallographica. Section D, Structural biology 78 (Pt 6) (2022)
Tika R Malla, Anthony Tumber, Tobias John, Lennart Brewitz, Claire Strain-Damerell, C David Owen, Petra Lukacik, H T Henry Chan, Pratheesh Maheswaran, Eidarus Salah, Fernanda Duarte, Haitao Yang, Zihe Rao, Martin Austin Walsh, Christopher J Schofield
Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mpro inhibitors. Chemical communications (Cambridge, England) 57 (12) (2021)
H T Henry Chan, Marc A Moesser, Rebecca K Walters, Tika R Malla, Rebecca M Twidale, Tobias John, Helen M Deeks, Tristan Johnston-Wood, Victor Mikhailov, Richard B Sessions, William Dawson, Eidarus Salah, Petra Lukacik, Claire Strain-Damerell, C David Owen, Takahito Nakajima, Katarzyna Świderek, Alessio Lodola, Vicent Moliner, David R Glowacki, James Spencer, Martin Austin Walsh, Christopher J Schofield, Luigi Genovese, Deborah K Shoemark, Adrian J Mulholland, Fernanda Duarte, Garrett M Morris
Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding. Chemical science 12 (41) (2021)
Alice Douangamath, Daren Fearon, Paul Gehrtz, Tobias Krojer, Petra Lukacik, C David Owen, Efrat Resnick, Claire Strain-Damerell, Anthony Aimon, Péter Ábrányi-Balogh, José Brandão-Neto, Anna Carbery, Gemma Davison, Alexandre Dias, Thomas D Downes, Louise Dunnett, Michael Fairhead, James D Firth, S Paul Jones, Aaron Keeley, György M Keserü, Hanna F Klein, Mathew P Martin, Martin E M Noble, Peter O'Brien, Ailsa J Powell, Rambabu N Reddi, Rachael E Skyner, Matthew Snee, Michael J Waring, Conor Wild, Nir London, Frank von Delft, Martin Austin Walsh
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nature communications 11 (1) (2020)
Andrew Bell, Jason Brunt, Emmanuelle Crost, Laura Vaux, Ridvan Nepravishta, C David Owen, Dimitrios Latousakis, An Xiao, Wanqing Li, Xi Chen, Martin Austin Walsh, Jan Claesen, Jesus Angulo, Gavin H Thomas, Nathalie Juge
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut. Nature microbiology 4 (12) (2019)
Jonathan M Grimes, David R Hall, Alun W Ashton, Gwyndaf Evans, Robin L Owen, Armin Wagner, Katherine Evelyn McAuley, Frank von Delft, Allen M Orville, Thomas Sorensen, Martin Austin Walsh, Helen Mary Ginn, David I Stuart
Where is crystallography going? Acta crystallographica. Section D, Structural biology 74 (Pt 2) (2018)
Pietro Roversi, Lucia Marti, Alessandro T Caputo, Dominic S Alonzi, Johan C Hill, Kyle C Dent, Abhinav Kumar, Mikail D Levasseur, Andrea Lia, Thomas Waksman, Souradeep Basu, Yentli Soto Albrecht, Kristin Qian, James Patrick McIvor, Colette B Lipp, Dritan Siliqi, Snežana Vasiljević, Shabaz Mohammed, Petra Lukacik, Martin Austin Walsh, Angelo Santino, Nicole Zitzmann
Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint. Proceedings of the National Academy of Sciences of the United States of America 114 (32) (2017)
Katrin Adamczyk, Niall Simpson, Gregory M Greetham, Andrea Gumiero, Martin Austin Walsh, Michael Towrie, Anthony W Parker, Neil T Hunt
Ultrafast infrared spectroscopy reveals water-mediated coherent dynamics in an enzyme active site. Chemical science 6 (1) (2014)

Martin Austin Walsh.css-eqlu8i{font-size:small;padding-left:4px;} (Martin Walsh, Martin A Walsh)

Publication Activity (10 Years)

Top Topics

Top Venues

Martin Austin Walsh (Martin Walsh, Martin A Walsh)