Nabeel El-Bardeesy (Nabeel Bardeesy)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Combination Therapy

Tyrosine Kinase

Top Venues

Nature communications

Cancer immunology research

Clinical cancer research : an official journal of the American Association for Cancer Research

This page only lists publications with an associated author ORCID identifier.

Publications

Yuanli Zhen, Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis, Eranga Roshan Balasooriya, Johannes Kreuzer, Robert Morris, Albert S Baldwin, Dejan Juric, Wilhelm Haas, Nabeel El-Bardeesy
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma. Nature communications 15 (1) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Jong Ho Park, Mahsa Mortaja, Heehwa G Son, Xutu Zhao, Lauren M Sloat, Marjan Azin, Jun Wang, Michael R Collier, Krishna S Tummala, Anna Mandinova, Nabeel El-Bardeesy, Yevgeniy R Semenov, Mari A Mino-Kenudson, Shadhmer Demehri
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nature communications 15 (1) (2024)
Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy. Cancer immunology research 12 (4) (2024)
Eranga Roshan Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran, Adithi Mohan, Eric Martin, Aleksandra Franovic, John S Tyhonas, Matthew Lardy, Kathryn B Grandinetti, Robert Pelham, Liliana Soroceanu, Vanessa Silva Silveira, Nabeel El-Bardeesy
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Eranga Roshan Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran, Adithi Mohan, Eric Martin, Aleksandra Franovic, John S Tyhonas, Matthew Lardy, Kathryn B Grandinetti, Robert Pelham, Liliana Soroceanu, Vanessa Silva Silveira, Nabeel El-Bardeesy
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Yuanli Zhen, Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis, Eranga Roshan Balasooriya, Johannes Kreuzer, Robert Morris, Albert S Baldwin, Dejan Juric, Wilhelm Haas, Nabeel El-Bardeesy
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma. Nature communications 15 (1) (2024)
Jong Ho Park, Mahsa Mortaja, Heehwa G Son, Xutu Zhao, Lauren M Sloat, Marjan Azin, Jun Wang, Michael R Collier, Krishna S Tummala, Anna Mandinova, Nabeel El-Bardeesy, Yevgeniy R Semenov, Mari A Mino-Kenudson, Shadhmer Demehri
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nature communications 15 (1) (2024)
Jong Ho Park, Mahsa Mortaja, Heehwa G Son, Xutu Zhao, Lauren M Sloat, Marjan Azin, Jun Wang, Michael R Collier, Krishna S Tummala, Anna Mandinova, Nabeel El-Bardeesy, Yevgeniy R Semenov, Mari A Mino-Kenudson, Shadhmer Demehri
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nature communications 15 (1) (2024)
Hiroyuki Kato, Nabeel El-Bardeesy
Illuminating the path to pancreatic cancer. Cell research (2024)
Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Jong Ho Park, Mahsa Mortaja, Heehwa G Son, Xutu Zhao, Lauren M Sloat, Marjan Azin, Jun Wang, Michael R Collier, Krishna S Tummala, Anna Mandinova, Nabeel El-Bardeesy, Yevgeniy R Semenov, Mari A Mino-Kenudson, Shadhmer Demehri
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nature communications 15 (1) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Eranga Roshan Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran, Adithi Mohan, Eric Martin, Aleksandra Franovic, John S Tyhonas, Matthew Lardy, Kathryn B Grandinetti, Robert Pelham, Liliana Soroceanu, Vanessa Silva Silveira, Nabeel El-Bardeesy
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Yuanli Zhen, Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis, Eranga Roshan Balasooriya, Johannes Kreuzer, Robert Morris, Albert S Baldwin, Dejan Juric, Wilhelm Haas, Nabeel El-Bardeesy
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma. Nature communications 15 (1) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy. Cancer immunology research 12 (4) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy. Cancer immunology research 12 (4) (2024)
Eranga Roshan Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran, Adithi Mohan, Eric Martin, Aleksandra Franovic, John S Tyhonas, Matthew Lardy, Kathryn B Grandinetti, Robert Pelham, Liliana Soroceanu, Vanessa Silva Silveira, Nabeel El-Bardeesy
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Jiang Chen, Zohreh Amoozgar, Xin Liu, Shuichi Aoki, Ze-Long Liu, Sarah M Shin, Aya Matsui, Alexei Hernandez, Zhangya Pu, Stefan Halvorsen, Pin-Ji Lei, Meenal Datta, Lingling Zhu, Zhi-Ping Ruan, Lei Shi, Daniel Staiculescu, Koetsu Inoue, Lance L Munn, Dai Fukumura, Peigen Huang, Slim Sassi, Nabeel El-Bardeesy, Won Jin Ho, Rakesh K Jain, Dan G Duda
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy. Cancer immunology research (2024)
Eranga Roshan Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran, Adithi Mohan, Eric Martin, Aleksandra Franovic, John S Tyhonas, Matthew Lardy, Kathryn B Grandinetti, Robert Pelham, Liliana Soroceanu, Vanessa Silva Silveira, Nabeel El-Bardeesy
The irreversible FGFR inhibitor KIN-3248 overcomes FGFR2 kinase domain mutations. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Yuanli Zhen, Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis, Eranga Roshan Balasooriya, Johannes Kreuzer, Robert Morris, Albert S Baldwin, Dejan Juric, Wilhelm Haas, Nabeel El-Bardeesy
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma. Nature communications 15 (1) (2024)
Christina K Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve, Keith M Hamel, Kira E Olander, Thomas G R Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Chirag H Patel, Sarah Y Kim, Ashwin V Kammula, Audrey J Muscato, Kyle Halliwill, Prasanthi Geda, Kelly L Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Rebecca Mathew, Carey Backus, Domenick E Kennedy, Angeline Chen, Kenton Longenecker, Joseph T Klahn, Cara L Hrusch, Navasona Krishnan, Charles W Hutchins, Jax P Dunning, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa A Ronan, Jennifer A Roth, Meng-Ju Wu, Juliette S M T Suermondt, Nelson H Knudsen, Collins K Cheruiyot, Debattama R Sen, Gabriel K Griffin, Todd R Golub, Nabeel El-Bardeesy, Joshua H Decker, Yi Yang, Magali Guffroy, Stacey Fossey, Patricia Trusk, Im-Meng Sun, Yue Liu, Wei Qiu, Qi Sun, Marcia N Paddock, Elliot P Farney, Mark A Matulenko, Clay Beauregard, Jennifer M Frost, Kathleen B Yates, Philip R Kym, Robert T Manguso
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity. Nature (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Qibiao Wu, Haley Ellis, Giulia Siravegna, Alexa G Michel, Bryanna L Norden, Ferran Fece de la Cruz, Eranga Roshan Balasooriya, Yuanli Zhen, Vanessa Silva Silveira, Jianwei Che, Ryan B Corcoran, Nabeel El-Bardeesy
Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Hiroyuki Kato, Haley Ellis, Nabeel El-Bardeesy
KRAS Wild-type Pancreatic Cancer: Decoding Genomics, Unlocking Therapeutic Potential. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Tim F Greten, Robert F Schwabe, Nabeel El-Bardeesy, Lichun Ma, Lipika Goyal, Robin Kate Kelley, Xin W Wang
Immunology and immunotherapy of cholangiocarcinoma. Nature reviews. Gastroenterology & hepatology (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Elia Aguado-Fraile, Ania Tassinari, Yuko Ishii, Carlie S Sigel, Maeve A Lowery, Lipika Goyal, Camelia Gliser, Liewen Jiang, Shuchi S Pandya, Bin Wu, Nabeel El-Bardeesy, Sung Choe, Vikram Deshpande
Molecular and morphological changes induced by ivosidenib correlate with efficacy in mutant-IDH1 cholangiocarcinoma. Future oncology (London, England) 17 (16) (2021)
Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Thomas F Baumert, Mozhdeh Sojoodi, Marine A Oudot, François H T Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S Kim, C Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T Chung, Beate K Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P Koh, Milind Mahajan, Venugopalan D Nair, Ganesh Gunasekaran, Myron E Schwartz, Nabeel El-Bardeesy, Alex K Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K Tanabe, Mathias F Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B Zeisel, Bryan C Fuchs, Yujin Hoshida, Thomas F Baumert
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. Nature communications 12 (1) (2021)
Xiaohong Tan, Lu Tong, Lin Li, Jinjin Xu, Shaofang Xie, Lei Ji, Junjiang Fu, Qingwu Liu, Shihui Shen, Yun Liu, Yanhui Xiao, Feiran Gao, Robb E Moses, Nabeel El-Bardeesy, Yanxiao Wang, Jishuai Zhang, Longying Tang, Lei Li, Kwok-Kin Wong, Dianwen Song, Guan Yang, Jian Liu, Xiaotao Li
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nature communications 12 (1) (2021)
Anca G Radu, Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas, Uwe Schlattner, Laurence Lafanechère, Pierre Hainaut, Nicolas Tricaud, Véronique Pingault, Nadège Bondurand, Nabeel El-Bardeesy, Lionel Larue, Chantal Thibert, Marc Billaud
LKB1 specifies neural crest cell fates through pyruvate-alanine cycling. Science advances 5 (7) (2019)
Krushna C Patra, Yasutaka Kato, Yusuke Mizukami, Sebastian Widholz, Myriam Boukhali, Iulia Revenco, Elizabeth A Grossman, Fei Ji, Ruslan I Sadreyev, Andrew S Liss, Robert A Screaton, Kei Sakamoto, David P Ryan, Mari Mino-Kenudson, Carlos Fernandez-Del Castillo, Daniel K Nomura, Wilhelm Haas, Nabeel El-Bardeesy
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism. Nature cell biology 20 (7) (2018)