Daria-Mochly Rosen (Daria Mochly-Rosen)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Alcohol Consumption

Amyotrophic Lateral Sclerosis

Endoplasmic Reticulum

Top Venues

Nature communications

Communications biology

Nature biotechnology

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Julio Cesar Batista Ferreira, Juliane C Campos, Nir Qvit, Xin Qi, Luiz H M Bozi, Luiz R G Bechara, Vanessa M Lima, Bruno Barros Queliconi, Marie-Helene Disatnik, Paulo M M Dourado, Alicia J Kowaltowski, Daria-Mochly Rosen
Author Correction: A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nature communications 15 (1) (2024)
Aly Elezaby, Amanda J Lin, Vijith Vijayan, Suman Pokhrel, Benjamin R Kraemer, Luiz Roberto Grassmann Bechara, Isabel Larus, Junhui Sun, Valentina Baena, Zulfeqhar A Syed, Elizabeth Murphy, Brian Glancy, Nicolai P Ostberg, Bruno B Queliconi, Juliane C Campos, Julio C B Ferreira, Bereketeab Haileselassie, Daria-Mochly Rosen
Cardiac troponin I directly binds and inhibits mitochondrial ATP synthase with a noncanonical role in the post-ischemic heart. Nature cardiovascular research 3 (8) (2024)
Jeewon Sylvia Kim, Stephen Kargotich, Sophia H Lee, Rieko Yajima, Adriana Ann Garcia, Gretchen Ehrenkaufer, Mary Romeo, Peter Santa Maria, Kevin V Grimes, Daria-Mochly Rosen
SPARKing academic technologies across the valley of death. Nature biotechnology 42 (2) (2024)
Jeewon Sylvia Kim, Stephen Kargotich, Sophia H Lee, Rieko Yajima, Adriana Ann Garcia, Gretchen Ehrenkaufer, Mary Romeo, Peter Santa Maria, Kevin V Grimes, Daria-Mochly Rosen
SPARKing academic technologies across the valley of death. Nature biotechnology 42 (2) (2024)
Jeewon Sylvia Kim, Stephen Kargotich, Sophia H Lee, Rieko Yajima, Adriana Ann Garcia, Gretchen Ehrenkaufer, Mary Romeo, Peter Santa Maria, Kevin V Grimes, Daria-Mochly Rosen
SPARKing academic technologies across the valley of death. Nature biotechnology 42 (2) (2024)
Aly Elezaby, Amanda J Lin, Vijith Vijayan, Suman Pokhrel, Benjamin R Kraemer, Luiz Roberto Grassmann Bechara, Isabel Larus, Junhui Sun, Valentina Baena, Zulfeqhar A Syed, Elizabeth Murphy, Brian Glancy, Nicolai P Ostberg, Bruno B Queliconi, Juliane C Campos, Julio C B Ferreira, Bereketeab Haileselassie, Daria-Mochly Rosen
Cardiac troponin I directly binds and inhibits mitochondrial ATP synthase with a noncanonical role in the post-ischemic heart. Nature cardiovascular research 3 (8) (2024)
Julio Cesar Batista Ferreira, Juliane C Campos, Nir Qvit, Xin Qi, Luiz H M Bozi, Luiz R G Bechara, Vanessa M Lima, Bruno Barros Queliconi, Marie-Helene Disatnik, Paulo M M Dourado, Alicia J Kowaltowski, Daria-Mochly Rosen
Author Correction: A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nature communications 15 (1) (2024)
An-Sheng Lee, Yen-Ling Sung, Szu-Hua Pan, Kuo-Tzu Sung, Cheng-Huang Su, Shiao-Li Ding, Ying-Jui Lu, Chin-Ling Hsieh, Yun-Fang Chen, Chuan-Chuan Liu, Wei-Yu Chen, Xuan-Ren Chen, Fa-Po Chung, Shih-Wei Wang, Che-Hong Chen, Daria-Mochly Rosen, Chung-Lieh Hung, Hung-I Yeh, Shien-Fong Lin
A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice. Communications biology 6 (1) (2023)
Hongchao Guo, Xuan Yu, Yu Liu, David T Paik, Johanne Marie Justesen, Joseph C Wu, James Won Suk Jahng, Tiejun Zhang, Weijun Wu, Freeborn Rwere, Shane Rui Zhao, Suman Pokhrel, Rabindra V Shivnaraine, Souhrid Mukherjee, Daniel J Simon, Amit Manhas, Angela Zhang, Che-Hong Chen, Manuel A Rivas, Eric R Gross, Daria-Mochly Rosen, Joseph C Wu
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Science translational medicine 15 (680) (2023)
Samuel P Flashner, Masataka Shimonosono, Yasuto Tomita, Norihiro Matsuura, Shinya Ohashi, Manabu Muto, Andres J Klein-Szanto, J Alan Diehl, Che-Hong Chen, Daria-Mochly Rosen, Kenneth I Weinberg, Hiroshi Nakagawa
ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment. Carcinogenesis (2023)
Yi-Cheng Chang, Hsiao-Lin Lee, Wenjin Yang, Meng-Lun Hsieh, Cai-Cin Liu, Tung-Yuan Lee, Jing-Yong Huang, Jiun-Yi Nong, Fu-An Li, Hsiao-Li Chuang, Zhi-Zhong Ding, Wei-Lun Su, Li-Yun Chueh, Yi-Ting Tsai, Che-Hong Chen, Daria-Mochly Rosen, Lee-Ming Chuang
A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators. Nature communications 14 (1) (2023)
Luis Rios, Suman Pokhrel, Sin-Jin Li, Gwangbeom Heo, Bereketeab Haileselassie, Daria-Mochly Rosen
Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nature communications 14 (1) (2023)
Scott Burkholz, Michael Rubsamen, Luke Blankenberg, Richard T Carback, Daria-Mochly Rosen, Paul E Harris
Analysis of well-annotated next-generation sequencing data reveals increasing cases of SARS-CoV-2 reinfection with Omicron. Communications biology 6 (1) (2023)
Hongchao Guo, Xuan Yu, Yu Liu, David T Paik, Johanne Marie Justesen, Joseph C Wu, James Won Suk Jahng, Tiejun Zhang, Weijun Wu, Freeborn Rwere, Shane Rui Zhao, Suman Pokhrel, Rabindra V Shivnaraine, Souhrid Mukherjee, Daniel J Simon, Amit Manhas, Angela Zhang, Che-Hong Chen, Manuel A Rivas, Eric R Gross, Daria-Mochly Rosen, Joseph C Wu
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Science translational medicine 15 (680) (2023)
Ligia A Kiyuna, Darlan S Candido, Luiz R G Bechara, Itamar C G Jesus, Lisley S Ramalho, Barbara Krum, Ruda P Albuquerque, Juliane C Campos, Luiz H M Bozi, Vanessa O Zambelli, Ariane N Alves, Nicolás Campolo, Mauricio Mastrogiovanni, Silvina Bartesaghi, Alejandro Leyva, Rosario Durán, Rafael Radi, Guilherme M Arantes, Edécio Cunha-Neto, Marcelo A Mori, Che-Hong Chen, Wenjin Yang, Daria-Mochly Rosen, Ian J MacRae, Ludmila R P Ferreira, Julio Cesar Batista Ferreira
4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification. European heart journal (2023)
Scott Burkholz, Michael Rubsamen, Luke Blankenberg, Richard T Carback, Daria-Mochly Rosen, Paul E Harris
Analysis of well-annotated next-generation sequencing data reveals increasing cases of SARS-CoV-2 reinfection with Omicron. Communications biology 6 (1) (2023)
Scott Burkholz, Michael Rubsamen, Luke Blankenberg, Richard T Carback, Daria-Mochly Rosen, Paul E Harris
Analysis of well-annotated next-generation sequencing data reveals increasing cases of SARS-CoV-2 reinfection with Omicron. Communications biology 6 (1) (2023)
Hongchao Guo, Xuan Yu, Yu Liu, David T Paik, Johanne Marie Justesen, Joseph C Wu, James Won Suk Jahng, Tiejun Zhang, Weijun Wu, Freeborn Rwere, Shane Rui Zhao, Suman Pokhrel, Rabindra V Shivnaraine, Souhrid Mukherjee, Daniel J Simon, Amit Manhas, Angela Zhang, Che-Hong Chen, Manuel A Rivas, Eric R Gross, Daria-Mochly Rosen, Joseph C Wu
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Science translational medicine 15 (680) (2023)
Scott Burkholz, Michael Rubsamen, Luke Blankenberg, Richard T Carback, Daria-Mochly Rosen, Paul E Harris
Analysis of well-annotated next-generation sequencing data reveals increasing cases of SARS-CoV-2 reinfection with Omicron. Communications biology 6 (1) (2023)
Che-Hong Chen, Wen-Lun Wang, Ming-Hung Hsu, Daria-Mochly Rosen
Alcohol Consumption, ALDH2 Polymorphism as Risk Factors for Upper Aerodigestive Tract Cancer Progression and Prognosis. Life (Basel, Switzerland) 12 (3) (2022)
Che-Hong Chen, Benjamin R Kraemer, Daria-Mochly Rosen
ALDH2 variance in disease and populations. Disease models & mechanisms 15 (6) (2022)
Nir Qvit, Amanda J Lin, Aly Elezaby, Nicolai P Ostberg, Juliane C Campos, Julio Cesar Batista Ferreira, Daria-Mochly Rosen
A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury. Pharmaceuticals (Basel, Switzerland) 15 (3) (2022)
Zhiping Feng, Marisa E Hom, Thomas E Bearrood, Zachary C Rosenthal, Daniel Fernández, Alison E Ondrus, Yuchao Gu, Aaron K McCormick, Madeline G Tomaske, Cody R Marshall, Toni Kline, Che-Hong Chen, Daria-Mochly Rosen, Calvin J Kuo, James K Chen
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Nature chemical biology 18 (10) (2022)
Vignesh Viswanathan, Hongbin Cao, Julie Saiki, Dadi Jiang, Aaron Mattingly, Dhanya Nambiar, Joshua D Bloomstein, Yang Li, Sizun J Jiang, Manish Chamoli, Davud Sirjani, Michael Kaplan, F Christopher Holsinger, Rachel Liang, Rie Von Eyben, Haowen Jiang, Li Guan, Edward Lagory, Zhiping Feng, Garry Nolan, Jiangbin Ye, Nicholas Denko, Sarah M Knox, Daria-Mochly Rosen, Quynh-Thu Le
Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype. PNAS nexus 1 (2) (2022)
Suman Pokhrel, Benjamin R Kraemer, Lucia Lee, Kate Samardzic, Daria-Mochly Rosen
Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis. PloS one 16 (5) (2021)
Bárbara B Martins, Natália G Hösch, Queren A Alcantara, Grant R Budas, Che-Hong Chen, Daria-Mochly Rosen, Julio Cesar Batista Ferreira, Vanessa Olzon Zambelli
Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice. Biomolecules 11 (12) (2021)
Naoki Horikoshi, Sunhee Hwang, Cornelius Gati, Tsutomu Matsui, Carlos Castillo-Orellana, Andrew G Raub, Adriana A Garcia, Fatemeh Jabbarpour, Alexander Batyuk, Joshua Broweleit, Xinyu Xiang, Andrew Chiang, Rachel Broweleit, Esteban Vöhringer-Martinez, Daria-Mochly Rosen, Soichi Wakatsuki
Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proceedings of the National Academy of Sciences of the United States of America 118 (4) (2021)
Paras S Minhas, Amira Latif-Hernandez, Melanie R McReynolds, Aarooran S Durairaj, Qian Wang, Amanda Rubin, Amit U Joshi, Joy Q He, Esha Gauba, Ling Liu, Congcong Wang, Miles H Linde, Yuki Sugiura, Peter K Moon, Ravi Majeti, Makoto Suematsu, Daria-Mochly Rosen, Irving L Weissman, Frank M Longo, Joshua D Rabinowitz, Katrin I Andreasson
Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature 590 (7844) (2021)
Shiau-Mei Chen, Siow-Wey Hee, Shih-Yun Chou, Meng-Wei Liu, Che-Hong Chen, Daria-Mochly Rosen, Tien-Jyun Chang, Lee-Ming Chuang
Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells. Biomolecules 11 (10) (2021)
Julio Cesar Batista Ferreira, Juliane C Campos, Nir Qvit, Xin Qi, Luiz H M Bozi, Luiz R G Bechara, Vanessa M Lima, Bruno Barros Queliconi, Marie-Helene Disatnik, Paulo M M Dourado, Alicia J Kowaltowski, Daria-Mochly Rosen
A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nature communications 10 (1) (2019)
Amit U Joshi, Lauren D Van Wassenhove, Kelsey R Logas, Paras S Minhas, Katrin I Andreasson, Kenneth I Weinberg, Che-Hong Chen, Daria-Mochly Rosen
Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology. Acta neuropathologica communications 7 (1) (2019)
Andrew G Raub, Sunhee Hwang, Naoki Horikoshi, Anna D Cunningham, Simin Rahighi, Soichi Wakatsuki, Daria-Mochly Rosen
Small-Molecule Activators of Glucose-6-phosphate Dehydrogenase (G6PD) Bridging the Dimer Interface. ChemMedChem 14 (14) (2019)
Amit U Joshi, Nay L Saw, Hannes Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria-Mochly Rosen
Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. EMBO molecular medicine 10 (3) (2019)
Amit U Joshi, Paras S Minhas, Shane A Liddelow, Bereketeab Haileselassie, Katrin I Andreasson, Gerald W Dorn, Daria-Mochly Rosen
Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration. Nature neuroscience 22 (10) (2019)
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel, Jeanne M Rumsey, Justin M Alberti, William C Knight, Nikolaos Biris, Emmanouil Zacharioudakis, James W Janetka, Robert H Baloh, Richard N Kitsis, Daria-Mochly Rosen, R Reid Townsend, Evripidis Gavathiotis, Gerald W Dorn
MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science (New York, N.Y.) 360 (6386) (2018)
Opher S Kornfeld, Nir Qvit, Bereketeab Haileselassie, Mehrdad Shamloo, Paolo Bernardi, Daria-Mochly Rosen
Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo. Scientific reports 8 (1) (2018)
Paras S Minhas, Ling Liu, Peter K Moon, Amit U Joshi, Christopher Dove, Siddhita Mhatre, Kevin Contrepois, Qian Wang, Brittany A Lee, Michael Coronado, Daniel Bernstein, Michael P Snyder, Marie Migaud, Ravindra Majeti, Daria-Mochly Rosen, Joshua D Rabinowitz, Katrin I Andreasson
Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation. Nature immunology 20 (1) (2018)
Sunhee Hwang, Karen Mruk, Simin Rahighi, Andrew G Raub, Che-Hong Chen, Lisa E Dorn, Naoki Horikoshi, Soichi Wakatsuki, James K Chen, Daria-Mochly Rosen
Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nature communications 9 (1) (2018)