Darius Babusis

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 16

Top Topics

Respiratory Syndrome Coronavirus

Lipopolysaccharide Induced

Combination Therapy

Top Venues

Science translational medicine

Science (New York, N.Y.)

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
Yuxia Lin, Mona Khan, Birgit Weynand, Manon Laporte, Frank Coenjaerts, Darius Babusis, John P Bilello, Peter Mombaerts, Dirk Jochmans, Johan Neyts
A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology. Nature communications 15 (1) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
Elizabeth E Zumbrun, Carly B Garvey, Jay B Wells, Ginger C Lynn, Sean Van Tongeren, Jesse T Steffens, Kelly S Wetzel, Laura M Gomba, Kristan A O'Brien, Franco D Rossi, Xiankun Zeng, Eric D Lee, Jo Lynne W Raymond, Diana A Hoffman, Alexandra N Jay, Elizabeth S Brown, Paul A Kallgren, Sarah L Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C Chu, Bali Singh, Roy Bannister, Danielle P Porter, Tomas Cihlar, John M Dye
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing. Viruses 15 (12) (2023)
Elizabeth E Zumbrun, Carly B Garvey, Jay B Wells, Ginger C Lynn, Sean Van Tongeren, Jesse T Steffens, Kelly S Wetzel, Laura M Gomba, Kristan A O'Brien, Franco D Rossi, Xiankun Zeng, Eric D Lee, Jo Lynne W Raymond, Diana A Hoffman, Alexandra N Jay, Elizabeth S Brown, Paul A Kallgren, Sarah L Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C Chu, Bali Singh, Roy Bannister, Danielle P Porter, Tomas Cihlar, John M Dye
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing. Viruses 15 (12) (2023)
Elizabeth E Zumbrun, Carly B Garvey, Jay B Wells, Ginger C Lynn, Sean Van Tongeren, Jesse T Steffens, Kelly S Wetzel, Laura M Gomba, Kristan A O'Brien, Franco D Rossi, Xiankun Zeng, Eric D Lee, Jo Lynne W Raymond, Diana A Hoffman, Alexandra N Jay, Elizabeth S Brown, Paul A Kallgren, Sarah L Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C Chu, Bali Singh, Roy Bannister, Danielle P Porter, Tomas Cihlar, John M Dye
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing. Viruses 15 (12) (2023)
Meghan S Vermillion, Eisuke Murakami, Bin Ma, Jared Pitts, Adrian Tomkinson, Davin Rautiola, Darius Babusis, Hammad Irshad, Dustin Seigel, Cynthia Kim, Xiaofeng Zhao, Congrong Niu, Jesse Yang, Andrew Gigliotti, Nani Kadrichu, John P Bilello, Scott Ellis, Roy Bannister, Raju Subramanian, Bill Smith, Richard L Mackman, William A Lee, Philip J Kuehl, Jim Hartke, Tomas Cihlar, Danielle P Porter
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection. Science translational medicine 14 (633) (2022)
Alexandra Schaefer, David R Martinez, John J Won, Rita M Meganck, Fernando R Moreira, Ariane J Brown, Kendra L Gully, Mark R Zweigart, William S Conrad, Samantha R May, Stephanie Dong, Rao Kalla, Kwon Chun, Venice Du Pont, Darius Babusis, Jennifer Tang, Eisuke Murakami, Raju Subramanian, Kimberly T Barrett, Blake J Bleier, Roy Bannister, Joy Y Feng, John P Bilello, Tomas Cihlar, Richard L Mackman, Stephanie A Montgomery, Ralph S Baric, Timothy P Sheahan
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice. Science translational medicine 14 (643) (2022)
Robert M Cox, Josef D Wolf, Carolin M Lieber, Julien Sourimant, Michelle J Lin, Darius Babusis, Venice DuPont, Julie Chan, Kim T Barrett, Diane Lye, Rao Kalla, Kwon Chun, Richard L Mackman, Chengjin Ye, Tomas Cihlar, Luis Martinez-Sobrido, Alexander L Greninger, John P Bilello, Richard K Plemper
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets. Nature communications 12 (1) (2021)
Timothy P Sheahan, Amy C Sims, Sarah R Leist, Alexandra Schäfer, John Won, Ariane J Brown, Stephanie A Montgomery, Alison Hogg, Darius Babusis, Michael O Clarke, Jamie E Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y Feng, Tomas Cihlar, Robert Jordan, Mark R Denison, Ralph S Baric
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nature communications 11 (1) (2020)
Timothy P Sheahan, Amy C Sims, Rachel L Graham, Vineet D Menachery, Lisa E Gralinski, James B Case, Sarah R Leist, Krzysztof Pyrc, Joy Y Feng, Iva Trantcheva, Roy Bannister, Yeojin Park, Darius Babusis, Michael O Clarke, Richard L Mackman, Jamie E Spahn, Christopher A Palmiotti, Dustin Siegel, Adrian S Ray, Tomas Cihlar, Robert Jordan, Mark R Denison, Ralph S Baric
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Science translational medicine 9 (396) (2018)