John P Bilello

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 29

Top Venues

Nature

Science translational medicine

Nature communications

Science (New York, N.Y.)

Gilead Sciences, Inc.

Pennsylvania State University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Gilead Sciences, Inc. Oct 14 2019

United States

Director :: Virology

Merck and Co Inc West Point Aug 04 2014 - Oct 10 2019

United States

Principal Scientist :: Infectious Diseases

Idenix Pharmaceuticals, Inc. Mar 07 2007 - Aug 04 2014

United States

Director :: Biology

Education History

Pennsylvania State University Jul 15 1998 - Jun 17 2002

United States

PHD :: Microbiology/Cell and Molecular Biology

Publications

David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
Yuxia Lin, Mona Khan, Birgit Weynand, Manon Laporte, Frank Coenjaerts, Darius Babusis, John P Bilello, Peter Mombaerts, Dirk Jochmans, Johan Neyts
A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology. Nature communications 15 (1) (2024)
Robert W Cross, Courtney Woolsey, Victor C Chu, Darius Babusis, Roy Bannister, Meghan S Vermillion, Romas Geleziunas, Kimberly T Barrett, Elaine Bunyan, Anh-Quan Nguyen, Tomas Cihlar, Danielle P Porter, Abhishek N Prasad, Daniel J Deer, Viktoriya Borisevich, Krystle N Agans, Jasmine Martinez, Mack B Harrison, Natalie S Dobias, Karla A Fenton, John P Bilello, Thomas W Geisbert
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus . Science (New York, N.Y.) 383 (6688) (2024)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Jared Pitts, Jiani Li, Jason K Perry, Venice Du Pont, Nicholas Riola, Lauren Rodriguez, Xianghan Lu, Chaitanya Kurhade, Xuping Xie, Gregory Camus, Savrina Manhas, Ross Martin, Pei-Yong Shi, Tomas Cihlar, Danielle P Porter, Hongmei Mo, Evguenia Maiorova, John P Bilello
Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants. Antimicrobial agents and chemotherapy 66 (6) (2022)
Meghan S Vermillion, Eisuke Murakami, Bin Ma, Jared Pitts, Adrian Tomkinson, Davin Rautiola, Darius Babusis, Hammad Irshad, Dustin Seigel, Cynthia Kim, Xiaofeng Zhao, Congrong Niu, Jesse Yang, Andrew Gigliotti, Nani Kadrichu, John P Bilello, Scott Ellis, Roy Bannister, Raju Subramanian, Bill Smith, Richard L Mackman, William A Lee, Philip J Kuehl, Jim Hartke, Tomas Cihlar, Danielle P Porter
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection. Science translational medicine 14 (633) (2022)
Alexandra Schaefer, David R Martinez, John J Won, Rita M Meganck, Fernando R Moreira, Ariane J Brown, Kendra L Gully, Mark R Zweigart, William S Conrad, Samantha R May, Stephanie Dong, Rao Kalla, Kwon Chun, Venice Du Pont, Darius Babusis, Jennifer Tang, Eisuke Murakami, Raju Subramanian, Kimberly T Barrett, Blake J Bleier, Roy Bannister, Joy Y Feng, John P Bilello, Tomas Cihlar, Richard L Mackman, Stephanie A Montgomery, Ralph S Baric, Timothy P Sheahan
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice. Science translational medicine 14 (643) (2022)
Xuping Xie, Antonio E Muruato, Xianwen Zhang, Kumari G Lokugamage, Camila R Fontes-Garfias, Jing Zou, Jianying Liu, Ping Ren, Mini Balakrishnan, Tomas Cihlar, Chien-Te Kent Tseng, Shinji Makino, Vineet D Menachery, John P Bilello, Pei-Yong Shi
Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19. Nature communications 12 (1) (2021)
Robert M Cox, Josef D Wolf, Carolin M Lieber, Julien Sourimant, Michelle J Lin, Darius Babusis, Venice DuPont, Julie Chan, Kim T Barrett, Diane Lye, Rao Kalla, Kwon Chun, Richard L Mackman, Chengjin Ye, Tomas Cihlar, Luis Martinez-Sobrido, Alexander L Greninger, John P Bilello, Richard K Plemper
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets. Nature communications 12 (1) (2021)
Jessica A Plante, Yang Liu, Jianying Liu, Hongjie Xia, Bryan A Johnson, Kumari G Lokugamage, Xianwen Zhang, Antonio E Muruato, Jing Zou, Camila R Fontes-Garfias, Divya Mirchandani, Dionna Scharton, John P Bilello, Zhiqiang Ku, Zhiqiang An, Birte Kalveram, Alexander N Freiberg, Vineet D Menachery, Xuping Xie, Kenneth S Plante, Scott C Weaver, Pei-Yong Shi
Spike mutation D614G alters SARS-CoV-2 fitness. Nature 592 (7852) (2020)
Xuping Xie, Antonio E Muruato, Xianwen Zhang, Kumari G Lokugamage, Camila R Fontes-Garfias, Jing Zou, Jianying Liu, Ping Ren, Mini Balakrishnan, Tomas Cihlar, Chien-Te Kent Tseng, Shinji Makino, Vineet D Menachery, John P Bilello, Pei-Yong Shi
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19. Nature communications 11 (1) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

John P Bilello