Jason K Perry (Jason Perry)

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 31

Top Venues

Nature

Science translational medicine

Viruses

Journal of medicinal chemistry

Gilead Sciences

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Gilead Sciences Jun 01 2006

United States

Senior Director :: Structural Chemistry

Schrödinger LLC Nov 01 1994 - May 31 2006

United States

Senior Applications Scientist

Publications

Charlotte Hedskog, Christoph D Spinner, Ulrike Protzer, Dieter Hoffmann, Chunkyu Ko, Robert L Gottlieb, Medhat Askar, Meta Roestenberg, Jutte J C de Vries, Ellen C Carbo, Ross Martin, Jiani Li, Dong Han, Lauren Rodriguez, Aiyappa Parvangada, Jason K Perry, Ricard Ferrer, Andres Anton, Cristina Andrés, Vanessa Casares, Huldrych F Gunthard, Michael Huber, Grace A McComsey, Navid Sadri, Judith A Aberg, Harm van Bakel, Danielle P Porter
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials. Viruses 16 (4) (2024)
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida, Davin Rautiola, Michael Keeney, Hammad Irshad, Lijun Zhang, Kwon Chun, Gregory Chin, Bindu Goyal, Edward Doerffler, Hai Yang, Michael O Clarke, Chris Palmiotti, Arya Vijjapurapu, Nicholas C Riola, Kirsten Stray, Eisuke Murakami, Bin Ma, Ting Wang, Xiaofeng Zhao, Yili Xu, Gary Lee, Bruno Marchand, Minji Seung, Arabinda Nayak, Adrian Tomkinson, Nani Kadrichu, Scott Ellis, Ona Barauskas, Joy Y Feng, Jason K Perry, Michel Perron, John P Bilello, Philip J Kuehl, Raju Subramanian, Tomas Cihlar, Richard L Mackman
Discovery of GS-7682, a Novel 4'-Cyano-Modified C -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys. Journal of medicinal chemistry 67 (15) (2024)
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida, Davin Rautiola, Michael Keeney, Hammad Irshad, Lijun Zhang, Kwon Chun, Gregory Chin, Bindu Goyal, Edward Doerffler, Hai Yang, Michael O Clarke, Chris Palmiotti, Arya Vijjapurapu, Nicholas C Riola, Kirsten Stray, Eisuke Murakami, Bin Ma, Ting Wang, Xiaofeng Zhao, Yili Xu, Gary Lee, Bruno Marchand, Minji Seung, Arabinda Nayak, Adrian Tomkinson, Nani Kadrichu, Scott Ellis, Ona Barauskas, Joy Y Feng, Jason K Perry, Michel Perron, John P Bilello, Philip J Kuehl, Raju Subramanian, Tomas Cihlar, Richard L Mackman
Discovery of GS-7682, a Novel 4'-Cyano-Modified C -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys. Journal of medicinal chemistry 67 (15) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Charlotte Hedskog, Christoph D Spinner, Ulrike Protzer, Dieter Hoffmann, Chunkyu Ko, Robert L Gottlieb, Medhat Askar, Meta Roestenberg, Jutte J C de Vries, Ellen C Carbo, Ross Martin, Jiani Li, Dong Han, Lauren Rodriguez, Aiyappa Parvangada, Jason K Perry, Ricard Ferrer, Andres Anton, Cristina Andrés, Vanessa Casares, Huldrych F Gunthard, Michael Huber, Grace A McComsey, Navid Sadri, Judith A Aberg, Harm van Bakel, Danielle P Porter
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials. Viruses 16 (4) (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Charlotte Hedskog, Christoph D Spinner, Ulrike Protzer, Dieter Hoffmann, Chunkyu Ko, Robert L Gottlieb, Medhat Askar, Meta Roestenberg, Jutte J C de Vries, Ellen C Carbo, Ross Martin, Jiani Li, Dong Han, Lauren Rodriguez, Aiyappa Parvangada, Jason K Perry, Ricard Ferrer, Andres Anton, Cristina Andrés, Vanessa Casares, Huldrych F Gunthard, Michael Huber, Grace A McComsey, Navid Sadri, Judith A Aberg, Harm van Bakel, Danielle P Porter
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials. Viruses 16 (4) (2024)
Charlotte Hedskog, Christoph D Spinner, Ulrike Protzer, Dieter Hoffmann, Chunkyu Ko, Robert L Gottlieb, Medhat Askar, Meta Roestenberg, Jutte J C de Vries, Ellen C Carbo, Ross Martin, Jiani Li, Dong Han, Lauren Rodriguez, Aiyappa Parvangada, Jason K Perry, Ricard Ferrer, Andres Anton, Cristina Andrés, Vanessa Casares, Huldrych F Gunthard, Michael Huber, Grace A McComsey, Navid Sadri, Judith A Aberg, Harm van Bakel, Danielle P Porter
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials. Viruses 16 (4) (2024)
Dustin S Siegel, Hon C Hui, Jared Pitts, Meghan S Vermillion, Kazuya Ishida, Davin Rautiola, Michael Keeney, Hammad Irshad, Lijun Zhang, Kwon Chun, Gregory Chin, Bindu Goyal, Edward Doerffler, Hai Yang, Michael O Clarke, Chris Palmiotti, Arya Vijjapurapu, Nicholas C Riola, Kirsten Stray, Eisuke Murakami, Bin Ma, Ting Wang, Xiaofeng Zhao, Yili Xu, Gary Lee, Bruno Marchand, Minji Seung, Arabinda Nayak, Adrian Tomkinson, Nani Kadrichu, Scott Ellis, Ona Barauskas, Joy Y Feng, Jason K Perry, Michel Perron, John P Bilello, Philip J Kuehl, Raju Subramanian, Tomas Cihlar, Richard L Mackman
Discovery of GS-7682, a Novel 4'-Cyano-Modified C -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys. Journal of medicinal chemistry (2024)
David R Martinez, Fernando R Moreira, Nicholas J Catanzaro, Meghan V Diefenbacher, Mark R Zweigart, Kendra L Gully, Gabriela de la Cruz, Ariane J Brown, Lily E Adams, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Cameron Nguyen, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, John P Bilello, Alexandra Schaefer, Timothy P Sheahan
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses. Science translational medicine 16 (748) (2024)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature 614 (7949) (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
David R Martinez, Fernando R Moreira, Mark R Zweigart, Kendra L Gully, Gabriela De la Cruz, Ariane J Brown, Lily E Adams, Nicholas Catanzaro, Boyd Yount, Thomas J Baric, Michael L Mallory, Helen Conrad, Samantha R May, Stephanie Dong, D Trevor Scobey, Stephanie A Montgomery, Jason K Perry, Darius Babusis, Kimberly T Barrett, Anh-Hoa Nguyen, Anh-Quan Nguyen, Rao Kalla, Roy Bannister, John P Bilello, Joy Y Feng, Tomas Cihlar, Ralph S Baric, Richard L Mackman, Alexandra Schäfer, Timothy P Sheahan
Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential. bioRxiv : the preprint server for biology (2023)
Brandon F Malone, Jason K Perry, Paul Dominic B Olinares, Hery W Lee, James Chen, Todd C Appleby, Joy Y Feng, John P Bilello, Honkit Ng, Johanna Sotiris, Mark Ebrahim, Eugene Y D Chua, Joshua H Mendez, Edward T Eng, Robert Landick, Matthias Götte, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature (2023)
James Chen, Qi Wang, Brandon F Malone, Eliza Llewellyn, Yakov Pechersky, Kashyap Maruthi, Edward T Eng, Jason K Perry, Elizabeth A Campbell, David E Shaw, Seth A Darst
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nature structural & molecular biology 29 (3) (2022)
Laura J Stevens, Andrea J Pruijssers, Hery W Lee, Calvin J Gordon, Egor P Tchesnokov, Jennifer Gribble, Amelia S George, Tia M Hughes, Xiaotao Lu, Jiani Li, Jason K Perry, Danielle P Porter, Tomas Cihlar, Timothy P Sheahan, Ralph S Baric, Matthias Götte, Mark R Denison
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms. Science translational medicine 14 (656) (2022)
Joy Y Feng, Venice Du Pont, Darius Babusis, Calvin J Gordon, Egor P Tchesnokov, Jason K Perry, Vincent Duong, Arya Vijjapurapu, Xiaofeng Zhao, Julie Chan, Cal Cohen, Kavita Juneja, Tomas Cihlar, Matthias Götte, John P Bilello
The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2. Molecules (Basel, Switzerland) 27 (13) (2022)
Calvin J Gordon, Egor P Tchesnokov, Emma Woolner, Jason K Perry, Joy Y Feng, Danielle P Porter, Matthias Götte
Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency. The Journal of biological chemistry 295 (20) (2020)
Richard L Mackman, Michael Mish, Gregory Chin, Jason K Perry, Todd Appleby, Vangelis Aktoudianakis, Sammy Metobo, Peter Pyun, Congrong Niu, Stephane Daffis, Helen Yu, Jim Zheng, Armando G Villasenor, Jeff Zablocki, Jason Chamberlain, Haolun Jin, Gary Lee, Kimberley Suekawa-Pirrone, Rex Santos, William E Delaney, Simon P Fletcher
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B. Journal of medicinal chemistry 63 (18) (2020)

Jason K Perry.css-eqlu8i{font-size:small;padding-left:4px;} (Jason Perry)

Publication Activity (10 Years)

Top Topics

Top Venues

Jason K Perry (Jason Perry)