Richard K Plemper (Richard Plemper)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 46

Top Topics

Respiratory Syncytial Virus

Structural Basis

Helicobacter Pylori

Top Venues

Nature communications

Nature microbiology

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Carolin M Lieber, Hae-Ji Kang, Elizabeth B Sobolik, Zachary M Sticher, Vu L Ngo, Andrew T Gewirtz, Alexander A Kolykhalov, Michael G Natchus, Alexander L Greninger, Mehul S Suthar, Richard K Plemper
Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection. bioRxiv : the preprint server for biology (2024)
Josef D Wolf, Richard K Plemper
A three-way interface of the Nipah virus phosphoprotein X-domain coordinates polymerase movement along the viral genome. Journal of virology (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Carolin M Lieber, Hae-Ji Kang, Elizabeth B Sobolik, Zachary M Sticher, Vu L Ngo, Andrew T Gewirtz, Alexander A Kolykhalov, Michael G Natchus, Alexander L Greninger, Mehul S Suthar, Richard K Plemper
Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection. bioRxiv : the preprint server for biology (2024)
Carolin M Lieber, Hae-Ji Kang, Elizabeth B Sobolik, Zachary M Sticher, Vu L Ngo, Andrew T Gewirtz, Alexander A Kolykhalov, Michael G Natchus, Alexander L Greninger, Mehul S Suthar, Richard K Plemper
Efficacy of late-onset antiviral treatment in immunocompromised hosts with persistent SARS-CoV-2 infection. Journal of virology (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Michael H J Rhodin, Archie C Reyes, Anand Balakrishnan, Nalini Bisht, Nicole M Kelly, Joyce Sweeney Gibbons, Jonathan Lloyd, Michael Vaine, Tessa Cressey, Miranda Crepeau, Ruichao Shen, Nathan Manalo, Jonathan Castillo, Rachel E Levene, Daniel Leonard, Tianzhu Zang, Lijuan Jiang, Kellye Daniels, Robert M Cox, Carolin M Lieber, Josef D Wolf, Richard K Plemper, Sarah R Leist, Trevor Scobey, Ralph S Baric, Guoqiang Wang, Bryan Goodwin, Yat Sun Or
The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo. Nature communications 15 (1) (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Michael H J Rhodin, Archie C Reyes, Anand Balakrishnan, Nalini Bisht, Nicole M Kelly, Joyce Sweeney Gibbons, Jonathan Lloyd, Michael Vaine, Tessa Cressey, Miranda Crepeau, Ruichao Shen, Nathan Manalo, Jonathan Castillo, Rachel E Levene, Daniel Leonard, Tianzhu Zang, Lijuan Jiang, Kellye Daniels, Robert M Cox, Carolin M Lieber, Josef D Wolf, Richard K Plemper, Sarah R Leist, Trevor Scobey, Ralph S Baric, Guoqiang Wang, Bryan Goodwin, Yat Sun Or
The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo. Nature communications 15 (1) (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Robert M Cox, Richard K Plemper
Design and Execution of In Vitro Polymerase Assays for Measles Virus and Related Mononegaviruses. Methods in molecular biology (Clifton, N.J.) 2808 (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Michael H J Rhodin, Archie C Reyes, Anand Balakrishnan, Nalini Bisht, Nicole M Kelly, Joyce Sweeney Gibbons, Jonathan Lloyd, Michael Vaine, Tessa Cressey, Miranda Crepeau, Ruichao Shen, Nathan Manalo, Jonathan Castillo, Rachel E Levene, Daniel Leonard, Tianzhu Zang, Lijuan Jiang, Kellye Daniels, Robert M Cox, Carolin M Lieber, Josef D Wolf, Richard K Plemper, Sarah R Leist, Trevor Scobey, Ralph S Baric, Guoqiang Wang, Bryan Goodwin, Yat Sun Or
The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo. Nature communications 15 (1) (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Carolin M Lieber, Hae-Ji Kang, Elizabeth B Sobolik, Zachary M Sticher, Vu L Ngo, Andrew T Gewirtz, Alexander A Kolykhalov, Michael G Natchus, Alexander L Greninger, Mehul S Suthar, Richard K Plemper
Efficacy of late-onset antiviral treatment in immunocompromised hosts with persistent SARS-CoV-2 infection. Journal of virology (2024)
Josef D Wolf, Michael R Sirrine, Robert M Cox, Richard K Plemper
Structural basis of paramyxo- and pneumovirus polymerase inhibition by non-nucleoside small-molecule antivirals. Antimicrobial agents and chemotherapy (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Robert M Cox, Josef D Wolf, Nicole A P Lieberman, Carolin M Lieber, Hae-Ji Kang, Zachary M Sticher, Jeong-Joong Yoon, Meghan K Smith, Mugunthan Govindarajan, Rebecca E Krueger, Elizabeth B Sobolik, Michael G Natchus, Andrew T Gewirtz, Rik L de Swart, Alexander A Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature communications 15 (1) (2024)
Carolin M Lieber, Hae-Ji Kang, Megha Aggarwal, Nicole A Lieberman, Elizabeth B Sobolik, Jeong-Joong Yoon, Michael G Natchus, Robert M Cox, Alexander L Greninger, Richard K Plemper
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo. PLoS pathogens 20 (2) (2024)
Satoshi Ikegame, Jillian C Carmichael, Heather L Wells, Robert L Furler O'Brien, Joshua A Acklin, Hsin-Ping Chiu, Kasopefoluwa Y Oguntuyo, Robert M Cox, Aum R Patel, Shreyas Kowdle, Christian S Stevens, Miles Eckley, Shijun Zhan, Jean K Lim, Ethan C Veit, Matthew J Evans, Takao Hashiguchi, Edison Durigon, Tony Schountz, Jonathan H Epstein, Richard K Plemper, Peter Daszak, Simon J Anthony, Benhur Lee
Metagenomics-enabled reverse-genetics assembly and characterization of myotis bat morbillivirus. Nature microbiology (2023)
Carolin M Lieber, Megha Aggarwal, Jeong-Joong Yoon, Robert M Cox, Hae-Ji Kang, Julien Sourimant, Mart Toots, Scott K Johnson, Cheryl A Jones, Zachary M Sticher, Alexander A Kolykhalov, Manohar T Saindane, Stephen M Tompkins, Oliver Planz, George R Painter, Michael G Natchus, Kaori Sakamoto, Richard K Plemper
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses. PLoS pathogens 19 (4) (2023)
Robert M Cox, Carolin M Lieber, Josef D Wolf, Amirhossein Karimi, Nicole A P Lieberman, Zachary M Sticher, Pavitra Roychoudhury, Meghan K Smith, Rebecca E Krueger, Michael G Natchus, George R Painter, Alexander A Kolykhalov, Alexander L Greninger, Richard K Plemper
Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models. Nature communications 14 (1) (2023)
Satoshi Ikegame, Jillian C Carmichael, Heather L Wells, Robert L Furler O'Brien, Joshua A Acklin, Hsin-Ping Chiu, Kasopefoluwa Y Oguntuyo, Robert M Cox, Aum R Patel, Shreyas Kowdle, Christian S Stevens, Miles Eckley, Shijun Zhan, Jean K Lim, Ethan C Veit, Matthew J Evans, Takao Hashiguchi, Edison Durigon, Tony Schountz, Jonathan H Epstein, Richard K Plemper, Peter Daszak, Simon J Anthony, Benhur Lee
Metagenomics-enabled reverse-genetics assembly and characterization of myotis bat morbillivirus. Nature microbiology (2023)
Julien Sourimant, Carolin M Lieber, Jeong-Joong Yoon, Mart Toots, Mugunthan Govindarajan, Venkata Udumula, Kaori Sakamoto, Michael G Natchus, Joseph Patti, John Vernachio, Richard K Plemper
Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase. Science advances 8 (25) (2022)
Carolin M Lieber, Robert M Cox, Julien Sourimant, Josef D Wolf, Kate Juergens, Quynh Phung, Manohar T Saindane, Meghan K Smith, Zachary M Sticher, Alexander A Kalykhalov, Michael G Natchus, George R Painter, Kaori Sakamoto, Alexander L Greninger, Richard K Plemper
SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model. Nature communications 13 (1) (2022)
J Thomas Beatty, Scott Adkins, Sergey V Alkhovsky, Tatjana Avšič Županc, María A Ayllón, Justin Bahl, Anne Balkema-Buschmann, Matthew J Ballinger, Martina Bandte, Martin Beer, Nicolás Bejerman, Eric Bergeron, Nadine Biedenkopf, Laurent Bigarré, Carol D Blair, Kim R Blasdell, Steven B Bradfute, Thomas Briese, Paul A Brown, Remy Bruggmann, Ursula Johanna Buchholz, Michael J Buchmeier, Alexander Bukreyev, Felicity Jane Burt, Carmen Büttner, Charles H Calisher, Thierry Candresse, Jeremy Carson, Inmaculada Casas, Kartik Chandran, Remi N Charrel, Yuya Chiaki, Anya Crane, Mark Crane, Laurent Dacheux, Elena Dal Bó, Juan Carlos de la Torre, Xavier de Lamballerie, William Marciel de Souza, Rik L de Swart, Nolwenn M Dheilly, Nicholas Di Paola, Francesco Di Serio, Ralf Georg Dietzgen, Michele Digiaro, Jan Felix Drexler, W Paul Duprex, Ralf Dürrwald, Andrew J Easton, Toufic Elbeaino, Koray Ergunay, Guozhong Feng, Claudette Feuvrier, Andrew E Firth, Anthony R Fooks, Pierre B H Formenty, Juliana Freitas-Astúa, Selma Gago-Zachert, María Laura García, Adolfo García-Sastre, Aura R Garrison, Scott E Godwin, Jean-Paul J Gonzalez, Joëlle Goüy de Bellocq, Anthony Griffths, Martin Hermann Groschup, Stephan Gunther, John Hammond, Jussi M Hepojoki, Melanie M Hierweger, Seiji Hongō, Masayuki Horie, Hidenori Horikawa, Holly R Hughes, Adam J Hume, Timothy H Hyndman, Dao-Hong Jiang, Gilda B Jonson, Sandra Junglen, Fujio Kadono, David G Karlin, Boris Klempa, Jonas Klingström, Michel C Koch, Hideki Kondo, Eugene V Koonin, Jarmila Krásová, Mart Krupovic, Kenji Kubota, Ivan V Kuzmin, Piet Maes, Amy J Lambert, Jiànróng Lǐ, Jun-Min Li, François Lieffrig, Igor S Lukashevich, Dongsheng Luo, Piet Maes, Marco Marklewitz, Sergio H Marshall, Shin-Yi Lee Marzano, John W McCauley, Ali Mirazimi, Peter G Mohr, Nick J G Moody, Yasuaki Morita, Richard N Morrison, Elke Mühlberger, Rayapati A Naidu, Tomohide Natsuaki, Jose Antonio Navarro, Yutaro Neriya, Sergey V Netesov, Gabriele Neumann, Norbert Nowotny, Francisco M Ochoa-Corona, Gustavo F Palacios, Laurane Pallandre, Vicente Pallas, Anna Papa, Sofia Paraskevopoulou, Colin R Parrish, Alex Pauvolid-Corrêa, Janusz T Pawęska, Daniel R Pérez, Florian Pfaff, Richard K Plemper, Thomas S Postler, Françoise Pozet, Sheli R Radoshitzky, Pedro Luis Ramos-González, Marius Rehanek, Renato O Resende, Carina A Reyes, Víctor Romanowski, Dennis Rubbenstroth, Luisa Rubino, Artemis Rumbou, Jonathan A Runstadler, Melanie Rupp, Sead Sabanadzovic, Takahide Sasaya, Heike Schmidt-Posthaus, Martin Schwemmle, Torsten Seuberlich, Stephen R Sharpe, Mang Shi, Manuela Sironi, Sophie J Smither, Jin-Won Song, Kirsten M Spann, Jessica R Spengler, Mark D Stenglein, Ayato Takada, Robert B Tesh, Jana Těšíková, Natalie J Thornburg, Nicole D Tischler, Yasuhiro Tomitaka, Keizo Tomonaga, Noël Tordo, Kenta Tsunekawa, Massimo Turina, Ioannis E Tzanetakis, Anna Maria Vaira, Bernadette G van den Hoogen, Bert Vanmechelen, Nikos Vasilakis, Martin Verbeek, Susanne von Bargen, Jiro Wada, Victoria Wahl, Peter J Walker, Anna Elizabeth Whitfield, John V Williams, Yuri I Wolf, Junki Yamasaki, Hironobu Yanagisawa, Gong-Yin Ye, Yong-Zhen Zhang, Arnfinn Lodden Økland
2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Archives of virology (2022)
Carolin M Lieber, Richard K Plemper
4'-Fluorouridine Is a Broad-Spectrum Orally Available First-Line Antiviral That May Improve Pandemic Preparedness. DNA and cell biology 41 (8) (2022)
Robert M Cox, Julien Sourimant, Mugunthan Govindarajan, Michael G Natchus, Richard K Plemper
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity. PLoS pathogens 17 (2) (2021)
Julien Sourimant, Carolin M Lieber, Megha Aggarwal, Robert M Cox, Josef D Wolf, Jeong-Joong Yoon, Mart Toots, Chengjin Ye, Zachary M Sticher, Alexander A Kolykhalov, Luis Martinez-Sobrido, Gregory R Bluemling, Michael G Natchus, George R Painter, Richard K Plemper
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication. Science (New York, N.Y.) (2021)
Alexander M Horspool, Chengjin Ye, Ting Y Wong, Brynnan P Russ, Katherine S Lee, Michael T Winters, Justin R Bevere, Theodore Kieffer, Ivan Martinez, Julien Sourimant, Alexander L Greninger, Richard K Plemper, James Denvir, Holly A Cyphert, Jordi B Torrelles, Luis Martinez-Sobrido, Frederick Heath Damron
SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy. bioRxiv : the preprint server for biology (2021)
Kevin Wittwer, Danielle E Anderson, Kristin Pfeffermann, Robert M Cox, Josef D Wolf, Sabine Santibanez, Annette Mankertz, Roland Plesker, Zachary M Sticher, Alexander A Kolkykhalov, Michael G Natchus, Christian K Pfaller, Richard K Plemper, Veronika von Messling
Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding. Nature communications 12 (1) (2021)
Benhur Lee, Satoshi Ikegame, Jillian C Carmichael, Heather L Wells, Robert L Furler O'Brien, Joshua Acklin, Hsin-Ping Chiu, Kasopefoluwa Oguntuyo, Robert M Cox, Aum Patel, Shreyas Kowdle, Christian Stevens, Miles Eckley, Shijun Zhan, Jean Lim, Takao Hashiguchi, Edison Luís Durigon, Tony Schountz, Jonathan H Epstein, Richard K Plemper, Peter Daszak, Simon Anthony
Zoonotic potential of a novel bat morbillivirus. Research square (2021)
Robert M Cox, Josef D Wolf, Carolin M Lieber, Julien Sourimant, Michelle J Lin, Darius Babusis, Venice DuPont, Julie Chan, Kim T Barrett, Diane Lye, Rao Kalla, Kwon Chun, Richard L Mackman, Chengjin Ye, Tomas Cihlar, Luis Martinez-Sobrido, Alexander L Greninger, John P Bilello, Richard K Plemper
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets. Nature communications 12 (1) (2021)
Robert M Cox, Josef D Wolf, Richard K Plemper
Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets. Nature microbiology 6 (1) (2020)
Julien Sourimant, Vidhi D Thakkar, Robert M Cox, Richard K Plemper
Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics. Science advances 6 (10) (2020)
Robert M Cox, Julien Sourimant, Mart Toots, Jeong-Joong Yoon, Satoshi Ikegame, Mugunthan Govindarajan, Ruth E Watkinson, Patricia Thibault, Negar Makhsous, Michelle J Lin, Jose R Marengo, Zachary M Sticher, Alexander A Kolykhalov, Michael G Natchus, Alexander L Greninger, Benhur Lee, Richard K Plemper
Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase. Nature microbiology 5 (10) (2020)
Mart Toots, Jeong-Joong Yoon, Robert M Cox, Michael Hart, Zachary M Sticher, Negar Makhsous, Roland Plesker, Alec H Barrena, Prabhakar G Reddy, Deborah G Mitchell, Ryan C Shean, Gregory R Bluemling, Alexander A Kolykhalov, Alexander L Greninger, Michael G Natchus, George R Painter, Richard K Plemper
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Science translational medicine 11 (515) (2020)
T J Sego, Josua O Aponte-Serrano, Juliano Ferrari Gianlupi, Samuel R Heaps, Kira Breithaupt, Lutz Brusch, Jessica R Crawshaw, James M Osborne, Ellen M Quardokus, Richard K Plemper, James A Glazier
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness. PLoS computational biology 16 (12) (2020)
Venice Du Pont, Yi Jiang, Richard K Plemper
Bipartite interface of the measles virus phosphoprotein X domain with the large polymerase protein regulates viral polymerase dynamics. PLoS pathogens 15 (8) (2019)
Richard K Plemper, Robert M Cox
Biology must develop herd immunity against bad-actor molecules. PLoS pathogens 14 (6) (2018)
Alberto Jiménez-Somarribas, Shuli Mao, Jeong-Joong Yoon, Marco Weisshaar, Robert M Cox, Jose R Marengo, Deborah G Mitchell, Zachary P Morehouse, Dan Yan, Ivan Solis, Courtney C Aldrich, Michael G Natchus, Richard K Plemper
Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex. Journal of medicinal chemistry 60 (6) (2017)