Kris C Wood (Kris Wood)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 40

Top Venues

NPJ precision oncology

Nature cancer

Molecular cancer therapeutics

Nature communications

Duke University

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Duke University Aug 01 2012

United States

Assistant Professor :: Pharmacology and Cancer Biology

Education History

Massachusetts Institute of Technology Sep 01 2002 - May 01 2007

United States

PHD

Publications

Daniel P Nussbaum, Colin A Martz, Andrew M Waters, Alejandro Barrera, Annie Liu, Justine C Rutter, Christian G Cerda-Smith, Amy E Stewart, Chao Wu, Merve Cakir, Cecilia B Levandowski, David E Kantrowitz, Shannon J McCall, Mariaelena Pierobon, Emanuel F Petricoin, J Joshua Smith, Timothy E Reddy, Channing J Der, Dylan J Taatjes, Kris C Wood
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers. NPJ precision oncology 8 (1) (2024)
Lois M Kelly, Justine C Rutter, Kevin H Lin, Frank Ling, Matthieu Duchmann, Emmanuelle Latour, Nadia Arang, Hélène Pasquer, Duong Ho Nhat, Juliette Charles, Shane T Killarney, Hazel Xiaohui Ang, Federica Namor, Cécile Culeux, Berangere Lombard, Damarys Loew, Danielle L Swaney, Nevan J Krogan, Luc Brunel, Élodie Carretero, Pascal Verdié, Muriel Amblard, Sofiane Fodil, Tony Huynh, Marie Sébert, Lionel Ades, Emmanuel Raffoux, Nina Fenouille, Raphaël A Itzykson, Camille Lobry, Lina Benajiba, Antoine Forget, Anthony R Martin, Kris C Wood, Alexandre Puissant
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nature cancer 5 (7) (2024)
Lois M Kelly, Justine C Rutter, Kevin H Lin, Frank Ling, Matthieu Duchmann, Emmanuelle Latour, Nadia Arang, Hélène Pasquer, Duong Ho Nhat, Juliette Charles, Shane T Killarney, Hazel Xiaohui Ang, Federica Namor, Cécile Culeux, Berangere Lombard, Damarys Loew, Danielle L Swaney, Nevan J Krogan, Luc Brunel, Élodie Carretero, Pascal Verdié, Muriel Amblard, Sofiane Fodil, Tony Huynh, Marie Sébert, Lionel Ades, Emmanuel Raffoux, Nina Fenouille, Raphaël A Itzykson, Camille Lobry, Lina Benajiba, Antoine Forget, Anthony R Martin, Kris C Wood, Alexandre Puissant
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nature cancer (2024)
Tona M Gilmer, Chun-Hsiang Lai, Kexiao Guo, Katherine Deland, Kathleen A Ashcraft, Amy E Stewart, Yaode Wang, Jianmin Fu, Kris C Wood, David G Kirsch, Michael B Kastan
A Novel Dual ATM/DNA-PK Inhibitor, XRD-0394, Potently Radiosensitizes and Potentiates PARP and Topoisomerase I Inhibitors. Molecular cancer therapeutics 23 (6) (2024)
Tona M Gilmer, Chun-Hsiang Lai, Kexiao Guo, Katherine Deland, Kathleen A Ashcraft, Amy E Stewart, Yaode Wang, Jianmin Fu, Kris C Wood, David G Kirsch, Michael B Kastan
A novel dual ATM/DNA-PK inhibitor, XRD-0394, potently radiosensitizes and potentiates PARP and topoisomerase I inhibitors. Molecular cancer therapeutics (2024)
Lois M Kelly, Justine C Rutter, Kevin H Lin, Frank Ling, Matthieu Duchmann, Emmanuelle Latour, Nadia Arang, Hélène Pasquer, Duong Ho Nhat, Juliette Charles, Shane T Killarney, Hazel Xiaohui Ang, Federica Namor, Cécile Culeux, Berangere Lombard, Damarys Loew, Danielle L Swaney, Nevan J Krogan, Luc Brunel, Élodie Carretero, Pascal Verdié, Muriel Amblard, Sofiane Fodil, Tony Huynh, Marie Sébert, Lionel Ades, Emmanuel Raffoux, Nina Fenouille, Raphaël A Itzykson, Camille Lobry, Lina Benajiba, Antoine Forget, Anthony R Martin, Kris C Wood, Alexandre Puissant
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nature cancer (2024)
Daniel P Nussbaum, Colin A Martz, Andrew M Waters, Alejandro Barrera, Annie Liu, Justine C Rutter, Christian G Cerda-Smith, Amy E Stewart, Chao Wu, Merve Cakir, Cecilia B Levandowski, David E Kantrowitz, Shannon J McCall, Mariaelena Pierobon, Emanuel F Petricoin, J Joshua Smith, Timothy E Reddy, Channing J Der, Dylan J Taatjes, Kris C Wood
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers. NPJ precision oncology 8 (1) (2024)
Tona M Gilmer, Chun-Hsiang Lai, Kexiao Guo, Katherine Deland, Kathleen A Ashcraft, Amy E Stewart, Yaode Wang, Jianmin Fu, Kris C Wood, David G Kirsch, Michael B Kastan
A Novel Dual ATM/DNA-PK Inhibitor, XRD-0394, Potently Radiosensitizes and Potentiates PARP and Topoisomerase I Inhibitors. Molecular cancer therapeutics 23 (6) (2024)
Lois M Kelly, Justine C Rutter, Kevin H Lin, Frank Ling, Matthieu Duchmann, Emmanuelle Latour, Nadia Arang, Hélène Pasquer, Duong Ho Nhat, Juliette Charles, Shane T Killarney, Hazel Xiaohui Ang, Federica Namor, Cécile Culeux, Berangere Lombard, Damarys Loew, Danielle L Swaney, Nevan J Krogan, Luc Brunel, Élodie Carretero, Pascal Verdié, Muriel Amblard, Sofiane Fodil, Tony Huynh, Marie Sébert, Lionel Ades, Emmanuel Raffoux, Nina Fenouille, Raphaël A Itzykson, Camille Lobry, Lina Benajiba, Antoine Forget, Anthony R Martin, Kris C Wood, Alexandre Puissant
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nature cancer (2024)
Daniel P Nussbaum, Colin A Martz, Andrew M Waters, Alejandro Barrera, Annie Liu, Justine C Rutter, Christian G Cerda-Smith, Amy E Stewart, Chao Wu, Merve Cakir, Cecilia B Levandowski, David E Kantrowitz, Shannon J McCall, Mariaelena Pierobon, Emanuel F Petricoin, J Joshua Smith, Timothy E Reddy, Channing J Der, Dylan J Taatjes, Kris C Wood
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers. NPJ precision oncology 8 (1) (2024)
Daniel P Nussbaum, Colin A Martz, Andrew M Waters, Alejandro Barrera, Annie Liu, Justine C Rutter, Christian G Cerda-Smith, Amy E Stewart, Chao Wu, Merve Cakir, Cecilia B Levandowski, David E Kantrowitz, Shannon J McCall, Mariaelena Pierobon, Emanuel F Petricoin, J Joshua Smith, Timothy E Reddy, Channing J Der, Dylan J Taatjes, Kris C Wood
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers. NPJ precision oncology 8 (1) (2024)
Jeff A Maltas, Shane T Killarney, Katherine R Singleton, Maximilian A R Strobl, Rachel Washart, Kris C Wood, Kevin B Wood
Drug dependence in cancer is exploitable by optimally constructed treatment holidays. Nature ecology & evolution (2023)
Christopher F Bassil, Grace R Anderson, Benjamin Mayro, Kayleigh N Askin, Peter S Winter, Samuel Gruber, Tierney M Hall, Jacob P Hoj, Christian G Cerda-Smith, Haley M Hutchinson, Shane T Killarney, Katherine R Singleton, Li Qin, Kévin Jubien-Girard, Cécile Favreau, Anthony R Martin, Guillaume Robert, Rachid Benhida, Patrick Auberger, Ann Marie Pendergast, David M Lonard, Alexandre Puissant, Kris C Wood
MCB-613 exploits a collateral sensitivity in drug resistant EGFR -mutant non-small cell lung cancer through covalent inhibition of KEAP1. bioRxiv : the preprint server for biology (2023)
Jeff A Maltas, Shane T Killarney, Katherine R Singleton, Maximilian A R Strobl, Rachel Washart, Kris C Wood, Kevin B Wood
Author Correction: Drug dependence in cancer is exploitable by optimally constructed treatment holidays. Nature ecology & evolution (2023)
Shane T Killarney, Rachel Washart, Ryan S Soderquist, Jacob P Hoj, Jamie Lebhar, Kevin H Lin, Kris C Wood
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis. Nature communications 14 (1) (2023)
Shane T Killarney, Rachel Washart, Ryan S Soderquist, Jacob P Hoj, Jamie Lebhar, Kevin H Lin, Kris C Wood
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis. Nature communications 14 (1) (2023)
Benjamin Mayro, Jacob P Hoj, Christian G Cerda-Smith, Haley M Hutchinson, Michael W Caminear, Hannah L Thrash, Peter S Winter, Suzanne E Wardell, Donald P McDonnell, Colleen Wu, Kris C Wood, Ann Marie Pendergast
ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1. Proceedings of the National Academy of Sciences of the United States of America 120 (16) (2023)
Shane T Killarney, Rachel Washart, Ryan S Soderquist, Jacob P Hoj, Jamie Lebhar, Kevin H Lin, Kris C Wood
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis. Nature communications 14 (1) (2023)
Hazel Xiaohui Ang, Natalia Sutiman, Xinyue L Deng, Annie Liu, Christian G Cerda-Smith, Haley M Hutchinson, Holly Kim, Luke C Bartelt, Qiang Chen, Alejandro Barrera, Jiaxing Lin, Zhecheng Sheng, Ian C McDowell, Timothy E Reddy, Christopher V Nicchitta, Kris C Wood
Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13. Proceedings of the National Academy of Sciences of the United States of America 120 (38) (2023)
Christopher F Bassil, Grace R Anderson, Benjamin Mayro, Kayleigh N Askin, Peter S Winter, Samuel Gruber, Tierney M Hall, Jacob P Hoj, Christian G Cerda-Smith, Haley M Hutchinson, Shane T Killarney, Katherine R Singleton, Li Qin, Kévin Jubien-Girard, Cécile Favreau, Anthony R Martin, Guillaume Robert, Rachid Benhida, Patrick Auberger, Ann Marie Pendergast, David M Lonard, Alexandre Puissant, Kris C Wood
MCB-613 exploits a collateral sensitivity in drug resistant EGFR -mutant non-small cell lung cancer through covalent inhibition of KEAP1. bioRxiv : the preprint server for biology (2023)
Kris C Wood
Hyperactivation of oncogenic driver pathways as a precision therapeutic strategy. Nature genetics (2023)
Kris C Wood, Daniel Nussbaum, Colin Martz, Andrew M Waters, Alejandro Barrera, Justine Rutter, Christian Cerda-Smith, Amy Stewart, Chao Wu, Merve Cakir, Cecilia Levandowski, David Kantrowitz, Shannon J McCall, Mariaelena Pierobon, Emanuel Petricoin Iii, J Smith, Channing J Der, Dylan Taatjes
Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers. Research square (2023)
Lyla J Stanland, Hazel Xiaohui Ang, Jacob P Hoj, Yunqiang Chu, Patrick Boon-Ooi Tan, Kris C Wood, Micah A Luftig
CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer. Molecular cancer research : MCR (2023)
Craig M Goodwin, Andrew M Waters, Jennifer E Klomp, Sehrish Javaid, Kirsten L Bryant, Clint A Stalnecker, Kristina Drizyte-Miller, Bjoern Papke, Runying Yang, Amber M Amparo, Irem Ozkan-Dagliyan, Elisa Baldelli, Valerie Calvert, Mariaelena Pierobon, Jessica A Sorrentino, Andrew P Beelen, Natalie Bublitz, Mareen Lüthen, Kris C Wood, Emanuel F Petricoin, Christine Sers, Autumn J McRee, Adrienne D Cox, Channing J Der
Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-mutant Pancreatic Cancer. Cancer research (2022)
Moiez Ali, Min Lu, Hazel Xiaohui Ang, Ryan S Soderquist, Christine E Eyler, Haley M Hutchinson, Carolyn Glass, Christopher F Bassil, Omar M Lopez, D Lucas Kerr, Christina J Falcon, Helena A Yu, Aaron N Hata, Collin M Blakely, Caroline E McCoach, Trever G Bivona, Kris C Wood
Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells. Science translational medicine 14 (638) (2022)
Kris C Wood, Jorge Silvio Gutkind
Challenges and Emerging Opportunities for Targeting mTOR in Cancer. Cancer research 82 (21) (2022)
Kevin H Lin, Justine C Rutter, Abigail Xie, Shane T Killarney, Camille Vaganay, Chaima Benaksas, Frank Ling, Gaetano Sodaro, Paul-Arthur Meslin, Christopher F Bassil, Nina Fenouille, Jacob P Hoj, Rachel Washart, Hazel X Ang, Christian G Cerda-Smith, Paul Chaintreuil, Arnaud Jacquel, Patrick Auberger, Antoine Forget, Raphaël A Itzykson, Min Lu, Jiaxing Lin, Mariaelena Pierobon, Zhecheng Sheng, Xinghai Li, Ashutosh Chilkoti, Kouros Owzar, David A Rizzieri, Timothy S Pardee, Lina Benajiba, Emanuel Petricoin, Alexandre Puissant, Kris C Wood
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia. Nature cancer 3 (7) (2022)
Sehrish Javaid, Antje Schaefer, Craig M Goodwin, Victoria V Nguyen, Frances L Massey, Mariaelena Pierobon, Da'Jhnae Gambrell-Sanders, Andrew M Waters, Kathryn N Lambert, J Nathaniel Diehl, G Aaron Hobbs, Kris C Wood, Emanuel F Petricoin, Channing J Der, Adrienne D Cox
Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma. Molecular cancer therapeutics 21 (5) (2022)
Kris C Wood
Drivers of intrinsic resistance. Nature chemical biology 18 (6) (2022)
Michael E Lidsky, Zechen Wang, Min Lu, Annie Liu, Shiao-Wen D Hsu, Shannon J McCall, Zhecheng Sheng, Joshua A Granek, Kouros Owzar, Karen S Anderson, Kris C Wood
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies. NPJ precision oncology 6 (1) (2022)
Natalia Garcia, Vanessa Del Pozo, Marielle E Yohe, Craig M Goodwin, Terry J Shackleford, Long Wang, Kunal Baxi, Yidong Chen, Anna T Rogojina, Sara M Zimmerman, Cody J Peer, William Douglas Figg, Myron S Ignatius, Kris C Wood, Peter J Houghton, Angelina V Vaseva
Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma. Molecular cancer therapeutics (2021)
Daniel Y Joh, Jacob T Heggestad, Shengwei Zhang, Grace R Anderson, Jayanta Bhattacharyya, Suzanne E Wardell, Simone A Wall, Amy B Cheng, Faris Albarghouthi, Jason Liu, Sachi Oshima, Angus M Hucknall, Terry Hyslop, Allison H S Hall, Kris C Wood, E Shelley Hwang, Kyle C Strickland, Qingshan Wei, Ashutosh Chilkoti
Author Correction: Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates. NPJ breast cancer 7 (1) (2021)
Benjamin B Yellen, Jon S Zawistowski, Eric A Czech, Caleb I Sanford, Elliott Daniel SoRelle, Micah A Luftig, Zachary G Forbes, Kris C Wood, Jeff Hammerbacher
Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses. Science advances 7 (38) (2021)
Daniel Y Joh, Jacob T Heggestad, Shengwei Zhang, Grace R Anderson, Jayanta Bhattacharyya, Suzanne E Wardell, Simone A Wall, Amy B Cheng, Faris Albarghouthi, Jason Liu, Sachi Oshima, Angus M Hucknall, Terry Hyslop, Allison H S Hall, Kris C Wood, E Shelley Hwang, Kyle C Strickland, Qingshan Wei, Ashutosh Chilkoti
Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates. NPJ breast cancer 7 (1) (2021)
Kris C Wood
Overcoming MCL-1-driven adaptive resistance to targeted therapies. Nature communications 11 (1) (2020)
Angela Su, Frank Ling, Camille Vaganay, Gaetano Sodaro, Chaïma Benaksas, Reinaldo Dal Bello, Antoine Forget, Bryann Pardieu, Kevin H Lin, Justine C Rutter, Christopher F Bassil, Gael Fortin, Justine Pasanisi, Iléana Antony-Debré, Gabriela Alexe, Jean-François Benoist, Alain Pruvost, Yana Pikman, Jun Qi, Marie-Hélène Schlageter, Jean-Baptiste Micol, Giovanni Roti, Thomas Cluzeau, Hervé Dombret, Claude Preudhomme, Nina Fenouille, Lina Benajiba, Hava M Golan, Kimberly Stegmaier, Camille Lobry, Kris C Wood, Raphael Itzykson, Alexandre Puissant
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies. Cancer discovery 10 (12) (2020)
Kevin H Lin, Justine C Rutter, Abigail Xie, Bryann Pardieu, Emily T Winn, Reinaldo Dal Bello, Antoine Forget, Raphael Itzykson, Yeong-Ran Ahn, Ziwei Dai, Raiyan T Sobhan, Grace R Anderson, Katherine R Singleton, Amy E Decker, Peter S Winter, Jason W Locasale, Lorin Crawford, Alexandre Puissant, Kris C Wood
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Nature genetics 52 (4) (2020)
Merve Cakir, Sayan Mukherjee, Kris C Wood
Label propagation defines signaling networks associated with recurrently mutated cancer genes. Scientific reports 9 (1) (2019)
Zheng Zhong, Sugunavathi Sepramaniam, Xin Hui Chew, Kris C Wood, May Ann Lee, Babita Madan, David M Virshup
PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers. Oncogene 38 (40) (2019)
Mandana T Manzari, Grace R Anderson, Kevin H Lin, Ryan S Soderquist, Merve Çakir, Mitchell Zhang, Chandler E Moore, Rachel N Skelton, Mareva Fevre, Xinghai Li, Joseph J Bellucci, Suzanne E Wardell, Simone A Costa, Kris C Wood, Ashutosh Chilkoti
Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models. Science advances 5 (9) (2019)

Kris C Wood.css-eqlu8i{font-size:small;padding-left:4px;} (Kris Wood)

Publication Activity (10 Years)

Top Topics

Top Venues

Kris C Wood (Kris Wood)