Kasper Harpsøe (K Harpsøe)

Scopus Author ID Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 18

Top Venues

Journal of medicinal chemistry

Nature chemical biology

Nature chemistry

Nature

University of Copenhagen

The Danish University of Pharmaceutical Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Jan 01 2014

Denmark

Academic Employee, Senior Scientist :: Department of Drug Design and Pharmacology

Education History

The Danish University of Pharmaceutical Sciences May 01 2003 - Aug 23 2006

Denmark

PHD :: Department of Medicinal Chemistry

The Royal Danish School of Pharmacy Sep 01 1995 - Jul 11 2001

Denmark

MSC :: Department of Medicinal Chemistry

Publications

Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Eline Pottie, Christian B M Poulie, Icaro A Simon, Kasper Harpsøe, Laura D'Andrea, Igor V Komarov, David E Gloriam, Anders A Jensen, Jesper L Kristensen, Christophe Pol Stove
Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT 2A Receptor Agonists. ACS chemical neuroscience (2023)
Emil Märcher Rørsted, Jitka Nykodemová, Kasper Harpsøe, Anders A Jensen, Jesper L Kristensen
Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT 2A Receptor Agonist. ACS medicinal chemistry letters 14 (3) (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Jimmy Caroli, Alibek Mamyrbekov, Kasper Harpsøe, Sahar Gardizi, Linda Dörries, Eshan Ghosh, Alexander Sebastian Hauser, Albert Jelke Kooistra, David E Gloriam
A community Biased Signaling Atlas. Nature chemical biology (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Christian B M Poulie, Eline Pottie, Icaro A Simon, Kasper Harpsøe, Laura D'Andrea, Igor V Komarov, David E Gloriam, Anders A Jensen, Christophe Pol Stove, Jesper L Kristensen
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT 2A Receptor Agonists. Journal of medicinal chemistry 65 (18) (2022)
Christian R O Bartling, Thomas M T Jensen, Shawna M Henry, Anna L Colliander, Vita Sereikaite, Marcella Wenzler, Palash Jain, Hans M Maric, Kasper Harpsøe, Søren W Pedersen, Louise S Clemmensen, Linda M Haugaard-Kedström, David E Gloriam, Angela Ho, Kristian Stro Mgaard
Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation. Journal of the American Chemical Society 143 (2) (2021)
Chihiro Nakamoto, Yuhei Goto, Yoko Tomizawa, Yuko Fukata, Masaki Fukata, Kasper Harpsøe, David E Gloriam, Kazuhiro Aoki, Tomonori Takeuchi
A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro. Molecular brain 14 (1) (2021)
Yali Zhou, Henrik Daver, Boris Trapkov, Lijie Wu, Meng Wu, Kasper Harpsøe, Patrick R Gentry, Kaiwen Liu, Marina Larionova, Junlin Liu, Na Chen, Hans Bräuner-Osborne, David E Gloriam, Tian Hua, Zhi-Jie Liu
Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell research 32 (2) (2021)
Peiyu Xu, Sijie Huang, Huibing Zhang, Chunyou Mao, X Edward Zhou, Xi Cheng, Icaro A Simon, Dan-Dan Shen, Hsin-Yung Yen, Carol V Robinson, Kasper Harpsøe, Bo Svensson, Jia Guo, Hualiang Jiang, David E Gloriam, Karsten Melcher, Yi Jiang, Yan Zhang, H Eric Xu
Structural insights into the lipid and ligand regulation of serotonin receptors. Nature 592 (7854) (2021)
Jacob Krall, Francesco Bavo, Christina B Falk-Petersen, Claus H Jensen, Julie O Nielsen, Yongsong Tian, Valeria Anglani, Kenneth Thermann Kongstad, Louise Piilgaard, Birgitte Nielsen, David E Gloriam, Jan Kehler, Anders A Jensen, Kasper Harpsøe, Petrine Wellendorph, Bente Frølund
Discovery of 2-(Imidazo[1,2- b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites. Journal of medicinal chemistry 62 (5) (2019)
Alessandro Giraudo, Jacob Krall, Francesco Bavo, Birgitte Nielsen, Kenneth Thermann Kongstad, Barbara Rolando, Rossella De Blasio, David E Gloriam, Rebekka Löffler, Louise Thiesen, Kasper Harpsøe, Karla A Frydenvang, Donatella Boschi, Petrine Wellendorph, Marco Lucio Lolli, Anders A Jensen, Bente Frølund
Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters. Journal of medicinal chemistry 62 (12) (2019)
Jacob Krall, Claus Hatt Jensen, Francesco Bavo, Christina Birkedahl Falk-Petersen, Anne Stæhr Haugaard, Stine Byskov Vogensen, Yongsong Tian, Mia Nittegaard-Nielsen, Sara Björk Sigurdardóttir, Jan Kehler, Kenneth Thermann Kongstad, David E Gloriam, Rasmus Prætorius Clausen, Kasper Harpsøe, Petrine Wellendorph, Bente Frølund
Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. Journal of medicinal chemistry 60 (21) (2017)
C Munk, Vignir Isberg, S Mordalski, Kasper Harpsøe, K Rataj, Alexander Sebastian Hauser, Peter Kolb, A J Bojarski, G Vriend, David E Gloriam
GPCRdb: the G protein-coupled receptor database - an introduction. British journal of pharmacology 173 (14) (2016)
Xiao-Feng Xiong, Hang Zhang, Christina R Underwood, Kasper Harpsøe, Thomas J Gardella, Mie F Wöldike, Michael Mannstadt, David E Gloriam, Hans Bräuner-Osborne, Kristian Stro Mgaard
Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors. Nature chemistry 8 (11) (2016)

Kasper Harpsøe.css-eqlu8i{font-size:small;padding-left:4px;} (K Harpsøe)

Publication Activity (10 Years)

Top Topics

Top Venues

Kasper Harpsøe (K Harpsøe)