Elena Aikawa

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 52

Top Topics

Top Venues

Arteriosclerosis, thrombosis, and vascular biology

European heart journal

Nature reviews. Cardiology

Journal of the American Heart Association

This page only lists publications with an associated author ORCID identifier.

Publications

Mark C Blaser, Fabrizio Buffolo, Arda Halu, Mandy E Turner, Florian Schlotter, Hideyuki Higashi, Lorena Pantano, Cassandra L Clift, Louis A Saddic, Samantha K Atkins, Maximillian A Rogers, Tan Pham, Amélie Vromman, Eugenia Shvartz, Galina K Sukhova, Silvia Monticone, Giovanni Camussi, Simon C Robson, Simon C Body, Jochen D Muehlschlegel, Sasha A Singh, Masanori Aikawa, Elena Aikawa
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis. Circulation (2023)
Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Phillippe Pibarot, Giampaolo Merlini, Robert S Rosenson, Surya V Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O Bonow, Olga Gursky, Jagat Narula
The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nature reviews. Cardiology (2023)
Mandy E Turner, Elena Aikawa
Updating the paradigm: inflammation as a targetable modulator of medial vascular calcification. Cardiovascular research 119 (13) (2023)
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet Rajendra Sonawane, Elena Aikawa
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European heart journal 44 (10) (2023)
Magdi H Yacoub, Yuan-Tsan Tseng, Jolanda Kluin, Annemijn Vis, Ulrich Stock, Hassiba Smail, Padmini Sarathchandra, Elena Aikawa, Hussam El-Nashar, Adrian H Chester, Nairouz Shehata, Mohamed Nagy, Amr El-Sawy, Wei Li, Gaetano Burriesci, Jacob Salmonsmith, Soha Romeih, Najma Latif
Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold. Communications biology 6 (1) (2023)
Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Phillippe Pibarot, Giampaolo Merlini, Robert S Rosenson, Surya V Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O Bonow, Olga Gursky, Jagat Narula
Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nature reviews. Cardiology (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology 43 (3) (2023)
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet Rajendra Sonawane, Elena Aikawa
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European heart journal (2023)
Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Phillippe Pibarot, Giampaolo Merlini, Robert S Rosenson, Surya V Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O Bonow, Olga Gursky, Jagat Narula
The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nature reviews. Cardiology (2023)
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet Rajendra Sonawane, Elena Aikawa
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European heart journal (2023)
Sneha Raju, Steven R Botts, Mark C Blaser, Kamalben Prajapati, Tse Wing Winnie Ho, Crizza Ching, Natalie J Galant, Lindsey Fiddes, Ruilin Wu, Cassandra L Clift, Tan Pham, Warren L Lee, Sasha A Singh, Elena Aikawa, Jason E Fish, Kathryn L Howe
Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall. bioRxiv : the preprint server for biology (2023)
Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Phillippe Pibarot, Giampaolo Merlini, Robert S Rosenson, Surya V Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O Bonow, Olga Gursky, Jagat Narula
The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nature reviews. Cardiology (2023)
Sneha Raju, Steven R Botts, Mark C Blaser, Kamalben Prajapati, Tse Wing Winnie Ho, Crizza Ching, Natalie J Galant, Lindsey Fiddes, Ruilin Wu, Cassandra L Clift, Tan Pham, Warren L Lee, Sasha A Singh, Elena Aikawa, Jason E Fish, Kathryn L Howe
Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall. bioRxiv : the preprint server for biology (2023)
Sneha Raju, Steven R Botts, Mark C Blaser, Kamalben Prajapati, Tse Wing Winnie Ho, Crizza Ching, Natalie J Galant, Lindsey Fiddes, Ruilin Wu, Cassandra L Clift, Tan Pham, Warren L Lee, Sasha A Singh, Elena Aikawa, Jason E Fish, Kathryn L Howe
Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall. bioRxiv : the preprint server for biology (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology 43 (3) (2023)
Arif Yurdagul, Elena Aikawa
Discovering a Rare Smooth Muscle Cell Population Specific to Males in Ascending Aortic Aneurysm Using Spatial Transcriptomics. Arteriosclerosis, thrombosis, and vascular biology (2023)
Julius L Decano, Enrico Maiorino, Joan T Matamalas, Sarvesh Chelvanambi, Bart M Tiemeijer, Yoshihiro Yanagihara, Shin Mukai, Prabhash Kumar Jha, Diego Vinicius Santinelli Pestana, Edwin D'Souza, Mary Whelan, Rile Ge, Takaharu Asano, Amitabh Sharma, Peter Libby, Sasha A Singh, Elena Aikawa, Masanori Aikawa
Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug-Gene Networks: From Biology to Precision Therapeutics. Circulation (2023)
Yen-Chun Ho, Xin Geng, Anna O'Donnell, Jaime Ibarrola, Amaya Fernandez-Celis, Rohan Varshney, Kumar Subramani, Zheila J Azartash-Namin, Jang Kim, Robert Silasi-Mansat, Jill Wylie-Sears, Zahra Alvandi, Lijuan Chen, Boksik Cha, Hong Chen, Lijun Xia, Bin Zhou, Florea Lupu, Harold M Burkhart, Elena Aikawa, Lorin E Olson, Jasimuddin Ahamed, Natalia Lopez-Andreés, Joyce Bischoff, Katherine E Yutzey, Rajanarayanan Sathishkumar Srinivasan
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circulation research (2023)
Sneha Raju, Steven R Botts, Mark C Blaser, Kamalben Prajapati, Tse Wing Winnie Ho, Crizza Ching, Natalie J Galant, Lindsey Fiddes, Ruilin Wu, Cassandra L Clift, Tan Pham, Warren L Lee, Sasha A Singh, Elena Aikawa, Jason E Fish, Kathryn L Howe
Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall. bioRxiv : the preprint server for biology (2023)
Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Phillippe Pibarot, Giampaolo Merlini, Robert S Rosenson, Surya V Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O Bonow, Olga Gursky, Jagat Narula
The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis. Nature reviews. Cardiology (2023)
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet Rajendra Sonawane, Elena Aikawa
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European heart journal 44 (10) (2023)
Francesca Bartoli-Leonard, Jonas Zimmer, Abhijeet R Sonawane, Katelyn Perez, Mandy E Turner, Shiori Kuraoka, Tan Pham, Feifei Li, Masanori Aikawa, Sasha A Singh, Luke Brewster, Elena Aikawa
NLRP3 Inflammasome Activation in Peripheral Arterial Disease. Journal of the American Heart Association 12 (6) (2023)
Francesca Bartoli-Leonard, Jonas Zimmer, Abhijeet R Sonawane, Katelyn Perez, Mandy E Turner, Shiori Kuraoka, Tan Pham, Feifei Li, Masanori Aikawa, Sasha A Singh, Luke Brewster, Elena Aikawa
NLRP3 Inflammasome Activation in Peripheral Arterial Disease. Journal of the American Heart Association (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology (2023)
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet Rajendra Sonawane, Elena Aikawa
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European heart journal (2023)
Francesca Bartoli-Leonard, Jonas Zimmer, Abhijeet R Sonawane, Katelyn Perez, Mandy E Turner, Shiori Kuraoka, Tan Pham, Feifei Li, Masanori Aikawa, Sasha A Singh, Luke Brewster, Elena Aikawa
NLRP3 Inflammasome Activation in Peripheral Arterial Disease. Journal of the American Heart Association 12 (6) (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology 43 (3) (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology 43 (3) (2023)
Maximillian A Rogers, Francesca Bartoli-Leonard, Kang H Zheng, Aeron M Small, Hao-Yu Chen, Cassandra L Clift, Takaharu Asano, Shiori Kuraoka, Mark C Blaser, Katelyn A Perez, Pradeep Natarajan, Calvin Yeang, Erik S G Stroes, Sotirios Tsimikas, James C Engert, George Thanassoulis, Christopher J O'Donnell, Masanori Aikawa, Sasha A Singh, Elena Aikawa
Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease. Circulation (2023)
Mark C Blaser, Simon Kraler, Thomas Felix Lüscher, Elena Aikawa
Network-Guided Multiomic Mapping of Aortic Valve Calcification. Arteriosclerosis, thrombosis, and vascular biology (2023)
Nadia R Sutton, Rajeev Malhotra, Cynthia St Hilaire, Elena Aikawa, Roger Scott Blumenthal, Grace Gackenbach, Parag Goyal, Adam Johnson, Sagar U Nigwekar, Catherine M Shanahan, Dwight A Towler, Brooke N Wolford, Yabing Chen
Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification. Arteriosclerosis, thrombosis, and vascular biology (2022)
Mandy E Turner, Francesca Bartoli-Leonard, Elena Aikawa
Small particles with large impact: Insights into the unresolved roles of innate immunity in extracellular vesicle-mediated cardiovascular calcification. Immunological reviews 312 (1) (2022)
Sean M Davidson, Chantal M Boulanger, Elena Aikawa, Lina Badimón, Lucio Barile, Christoph J Binder, Alain Brisson, Edit Irén Buzás, Costanza Emanueli, Felix Jansen, Miroslava Katsur, Romaric Lacroix, Sai Kiang Lim, Nigel Mackman, Manuel Mayr, Philippe Menasche, Rienk Nieuwland, Susmita Sahoo, Kaloyan Takov, Thomas Thum, Pieter Vader, Marca H M Wauben, Kennith W Witwer, Joost Petrus Gerardus Sluijter
Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles. Cardiovascular research (2022)
Rama Natarajan, Katherine Moore, Daisy Sahoo, Patrick Nana-Sinkam, Alpha A Berry Fowler, Patricia Sime, Mary G Sorci-Thomas, Elena Aikawa, null null
Shobha Ghosh (1958-2021). Arteriosclerosis, thrombosis, and vascular biology 42 (3) (2022)
Rama Natarajan, Katherine Moore, Daisy Sahoo, Patrick Nana-Sinkam, Alpha A Berry Fowler, Patricia Sime, Mary G Sorci-Thomas, Elena Aikawa, null null
Shobha Ghosh (1958-2021). Arteriosclerosis, thrombosis, and vascular biology 42 (3) (2022)
Shunsuke Katsuki, Prabhash K Jha, Adrien Lupieri, Toshiaki Nakano, Livia S A Passos, Maximillian A Rogers, Dakota Becker-Greene, Thanh-Dat Le, Julius L Decano, Lang Ho Lee, Gabriel C Guimaraes, Ilyes Abdelhamid, Arda Halu, Alessandro Muscoloni, Carlo V Cannistraci, Hideyuki Higashi, Hengmin Zhang, Amélie Vromman, Peter Libby, C Keith Ozaki, Amitabh Sharma, Sasha A Singh, Elena Aikawa, Masanori Aikawa
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms. Circulation research 131 (11) (2022)
Francesca Bartoli-Leonard, Jonas Zimmer, Elena Aikawa
Innate and adaptive immunity: the understudied driving force of heart valve disease. Cardiovascular research 117 (13) (2022)
Maximillian A Rogers, Joshua D Hutcheson, Takehito Okui, Claudia Goettsch, Sasha A Singh, Arda Halu, Florian Schlotter, Hideyuki Higashi, Lixiang Wang, Mary C Whelan, Andrew K Mlynarchik, Alan Daugherty, Masatoshi Nomura, Masanori Aikawa, Elena Aikawa
Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion. Cardiovascular research 117 (11) (2022)
Amélie Paquin, Ons Marsit, Valérie Deschênes, Dounia Rouabhia, Sandra Hadjadj, Marine Clisson, Charlotte Robitaille, Elena Aikawa, Robert A Levine, Phillippe Pibarot, Marie-Annick Clavel, Jonathan Beaudoin
Progression of aortic stenosis after an acute myocardial infarction. Open heart 9 (1) (2022)
Livia S A Passos, Victor Nizet, Robert A Levine, Elena Aikawa
Can we diagnose acute rheumatic fever early to maximize the success of secondary prophylaxis in rheumatic heart valve disease? Cardiovascular research 118 (9) (2022)
Rama Natarajan, Katherine Moore, Daisy Sahoo, Patrick Nana-Sinkam, Alpha A Berry Fowler, Patricia Sime, Mary G Sorci-Thomas, Elena Aikawa, null null
Shobha Ghosh (1958-2021). Arteriosclerosis, thrombosis, and vascular biology 42 (3) (2022)
Fabrizio Buffolo, Silvia Monticone, Giovanni Camussi, Elena Aikawa
Role of Extracellular Vesicles in the Pathogenesis of Vascular Damage. Hypertension (Dallas, Tex. : 1979) 79 (5) (2022)
Zahra Alvandi, Yasufumi Nagata, Livia Silva Araúujo Passos, Ali Hashemi Gheinani, J Luis Guerrero, Jill Wylie-Sears, Dayana Carolina Romero, Brittan A Morris, Suzanne M Sullivan, Koushiar M Yaghoubian, Amirhossein Alvandi, Rosalyn M Adam, Elena Aikawa, Robert A Levine, Joyce Bischoff
Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition. Journal of the American Heart Association 11 (7) (2022)
Jessica L Ruiz, Joshua D Hutcheson, Luis Cardoso, Amirala Bakhshian Nik, Alexandra Condado de Abreu, Tan Pham, Fabrizio Buffolo, Sara Busatto, Stefania Federici, Andrea Ridolfi, Masanori Aikawa, Sergio Bertazzo, Paolo Bergese, Sheldon Weinbaum, Elena Aikawa
Nanoanalytical analysis of bisphosphonate-driven alterations of microcalcifications using a 3D hydrogel system and in vivo mouse model. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Casper F T van der Ven, Mark W Tibbitt, João Conde, Alain van Mil, Jesper Hjortnaes, Pieter A M Doevendans, Joost Petrus Gerardus Sluijter, Elena Aikawa, Robert S Langer
Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel. Nanoscale (2021)
Maximillian A Rogers, Elena Aikawa
Unbiased omics identifies mechanistic regulators of calcific aortic valve disease. European heart journal 42 (30) (2021)
Uddalak Majumdar, Sathiyanarayanan Manivannan, Madhumita Basu, Yukie Ueyama, Mark C Blaser, Emily Cameron, Michael R McDermott, Joy Lincoln, Susan E Cole, Stephen A Wood, Elena Aikawa, Brenda Lilly, Vidu Garg
Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling. Science advances 7 (6) (2021)
Hiroshi Iwata, Eric A Osborn, Giovanni J Ughi, Kentaro Murakami, Claudia Goettsch, Joshua D Hutcheson, Adam Mauskapf, Peter C Mattson, Peter Libby, Sasha A Singh, Joan T Matamalas, Elena Aikawa, Guillermo J Tearney, Masanori Aikawa, Farouc A Jaffer
Highly Selective PPARα (Peroxisome Proliferator-Activated Receptor α) Agonist Pemafibrate Inhibits Stent Inflammation and Restenosis Assessed by Multimodality Molecular-Microstructural Imaging. Journal of the American Heart Association 10 (20) (2021)
Hanrui Zhang, Zhen Bouman Chen, Gabrielle Fredman, Delphine Gomez, Isabella M Grumbach, Ngan F Huang, Patricia Kim Phuong Nguyen, Mireille Ouimet, Nadia R Sutton, Elena Aikawa
What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award. Arteriosclerosis, thrombosis, and vascular biology 41 (11) (2021)
Maximillian A Rogers, Fabrizio Buffolo, Florian Schlotter, Samantha K Atkins, Lang Ho Lee, Arda Halu, Mark C Blaser, Elena Tsolaki, Hideyuki Higashi, Kristin Luther, George Daaboul, Carlijn V C Bouten, Simon C Body, Sasha A Singh, Sergio Bertazzo, Peter Libby, Masanori Aikawa, Elena Aikawa
Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis. Science advances 6 (38) (2020)
Maximillian A Rogers, Elena Aikawa
Complex association of lipoprotein(a) with aortic stenosis. Heart (British Cardiac Society) 106 (10) (2020)
Samantha K Atkins, Elena Aikawa
Valve under the microscope: shining a light on emerging technologies elucidating disease mechanisms. Heart (British Cardiac Society) 105 (21) (2019)