Frederick W Goldberg

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Communications biology

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Thomas G Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L Braybrooke, Andrew Campbell, Rodrigo J Carbajo, Azadeh Cheraghchi-Bashi, Elisabetta Chiarparin, Coura R Diène, Charlene Fallan, David I Fisher, Frederick W Goldberg, Lorna Hopcroft, Philip Hopcroft, Anne Jackson, Jason G Kettle, Teresa Klinowska, Ulrike Künzel, Gillian Lamont, Hilary J Lewis, Gareth Maglennon, Scott Martin, Pablo Morentin Gutierrez, Christopher J Morrow, Myria Nikolaou, J Willem M Nissink, Patrick O'Shea, Radoslaw Polanski, Markus Schade, James S Scott, Aaron Smith, Judith Weber, Joanne Wilson, Bin Yang, Claire Crafter
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC. Communications biology 7 (1) (2024)
Thomas G Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L Braybrooke, Andrew Campbell, Rodrigo J Carbajo, Azadeh Cheraghchi-Bashi, Elisabetta Chiarparin, Coura R Diène, Charlene Fallan, David I Fisher, Frederick W Goldberg, Lorna Hopcroft, Philip Hopcroft, Anne Jackson, Jason G Kettle, Teresa Klinowska, Ulrike Künzel, Gillian Lamont, Hilary J Lewis, Gareth Maglennon, Scott Martin, Pablo Morentin Gutierrez, Christopher J Morrow, Myria Nikolaou, J Willem M Nissink, Patrick O'Shea, Radoslaw Polanski, Markus Schade, James S Scott, Aaron Smith, Judith Weber, Joanne Wilson, Bin Yang, Claire Crafter
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC. Communications biology 7 (1) (2024)
Thomas G Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L Braybrooke, Andrew Campbell, Rodrigo J Carbajo, Azadeh Cheraghchi-Bashi, Elisabetta Chiarparin, Coura R Diène, Charlene Fallan, David I Fisher, Frederick W Goldberg, Lorna Hopcroft, Philip Hopcroft, Anne Jackson, Jason G Kettle, Teresa Klinowska, Ulrike Künzel, Gillian Lamont, Hilary J Lewis, Gareth Maglennon, Scott Martin, Pablo Morentin Gutierrez, Christopher J Morrow, Myria Nikolaou, J Willem M Nissink, Patrick O'Shea, Radoslaw Polanski, Markus Schade, James S Scott, Aaron Smith, Judith Weber, Joanne Wilson, Bin Yang, Claire Crafter
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTAC. Communications biology 7 (1) (2024)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology 18 (2) (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology 18 (2) (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology 18 (2) (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology 18 (2) (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology (2023)
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, Debora Ann Roaquin, Ronald Tomlinson, Andrea M Zuhl, Gillian M Lamont, Jason G Kettle, Susan E Critchlow, M Paola Castaldi, Frederick W Goldberg, Andrew X Zhang
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit. ACS chemical biology (2023)
Jason G Kettle, Sharan K Bagal, Derek Barratt, Michael S Bodnarchuk, Scott Boyd, Erin Braybrooke, Jason Breed, Doyle J Cassar, Sabina Cosulich, Michael Davies, Nichola L Davies, Chao Deng, Andrew Eatherton, Laura Evans, Lyman J Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Miguel A Cortés González, Carine Guerot, Afreen Haider, Stephanie Harlfinger, Rachel Howells, Anne Jackson, Peter Johnström, Paul D Kemmitt, Alex Koers, Mikhail Kondrashov, Gillian M Lamont, Scott Lamont, Hilary J Lewis, Libin Liu, Megan Mylrea, Samuel Nash, Michael J Niedbala, Alison Peter, Christopher Phillips, Kurt Pike, Piotr Raubo, Graeme R Robb, Sarah Ross, Matthew G Sanders, Magnus Schou, Iain Simpson, Oliver Steward
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS G12C with Demonstrable CNS Penetration. Journal of medicinal chemistry (2023)
Frederick W Goldberg, Attilla K T Ting, David Beattie, Gillian M Lamont, Charlene Fallan, M Raymond V Finlay, Beth Williamson, Marianne Schimpl, Alexander R Harmer, Oladipupo B Adeyemi, Pär Nordell, Anna S Cronin, Mercedes Vazquez-Chantada, Derek Barratt, Antonio Ramos-Montoya, Elaine B Cadogan, Barry R Davies
Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8 H -purin-8-one Inhibitors of DNA-PK. ACS medicinal chemistry letters 13 (8) (2022)
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Scott Boyd, Jason Breed, Rodrigo J Carbajo, Doyle J Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Nichola L Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Lyndsey Hanson, Stephanie Harlfinger, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Gillian Lamont, Scott Lamont, Hilary J Lewis, Libin Liu, Michael J Niedbala, Christopher Phillips, Radek Polanski, Piotr Raubo, Graeme R Robb, David M Robinson, Sarah Ross, Matthew G Sanders, Michael Tonge, Rebecca Whiteley, Stephen Wilkinson, Junsheng Yang, Wenman Zhang
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS G12C . Journal of medicinal chemistry 65 (9) (2022)
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, David Buttar, Attilla K T Ting, Thomas M McGuire, Calum R Cook, David Beattie, Pablo Morentin Gutierrez, Stefan L Kavanagh, Jasper C Komen, Aarti Kawatkar, Roger Clark, Lorna Hopcroft, Gareth Hughes, Susan E Critchlow
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology. Journal of medicinal chemistry 66 (1) (2022)
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, David Buttar, Attilla K T Ting, Thomas M McGuire, Calum R Cook, David Beattie, Pablo Morentin Gutierrez, Stefan L Kavanagh, Jasper C Komen, Aarti Kawatkar, Roger Clark, Lorna Hopcroft, Gareth Hughes, Susan E Critchlow
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology. Journal of medicinal chemistry 66 (1) (2022)
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, David Buttar, Attilla K T Ting, Thomas M McGuire, Calum R Cook, David Beattie, Pablo Morentin Gutierrez, Stefan L Kavanagh, Jasper C Komen, Aarti Kawatkar, Roger Clark, Lorna Hopcroft, Gareth Hughes, Susan E Critchlow
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology. Journal of medicinal chemistry 66 (1) (2022)
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, David Buttar, Attilla K T Ting, Thomas M McGuire, Calum R Cook, David Beattie, Pablo Morentin Gutierrez, Stefan L Kavanagh, Jasper C Komen, Aarti Kawatkar, Roger Clark, Lorna Hopcroft, Gareth Hughes, Susan E Critchlow
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology. Journal of medicinal chemistry (2022)
Alexey S Revenko, Larissa S Carnevalli, Charles Sinclair, Ben Johnson, Alison Peter, Molly Taylor, Lisa Hettrick, Melissa Chapman, Stephanie Klein, Anisha Solanki, Danielle Gattis, Andrew Watt, Adina M Hughes, Lukasz Magiera, Gozde Kar, Lucy Ireland, Deanna A Mele, Vasu Sah, Maneesh Singh, Josephine Walton, Maelle Mairesse, Matthew King, Mark Edbrooke, Paul Lyne, Simon T Barry, Stephen Fawell, Frederick W Goldberg, A Robert MacLeod
Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer. Journal for immunotherapy of cancer 10 (4) (2022)
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Jason Breed, Rodrigo J Carbajo, Doyle J Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Stephanie Harlfinger, Lyndsey Hanson, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Jennifer K Kingston, Scott Lamont, Hilary J Lewis, Songlei Li, Libin Liu, Derek Ogg, Christopher Phillips, Radek Polanski, Graeme R Robb, David Robinson, Sarah Ross, James M Smith, Michael Tonge, Rebecca Whiteley, Junsheng Yang, Longfei Zhang, Xiliang Zhao
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. Journal of medicinal chemistry 63 (9) (2020)
Frederick W Goldberg, M Raymond V Finlay, Attilla K T Ting, David Beattie, Gillian M Lamont, Charlene Fallan, Gail L Wrigley, Marianne Schimpl, Martin R Howard, Beth Williamson, Mercedes Vazquez-Chantada, Derek G Barratt, Barry R Davies, Elaine B Cadogan, Antonio Ramos-Montoya, Emma Dean
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor. Journal of medicinal chemistry 63 (7) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Frederick W Goldberg