Graeme R Robb (Graeme Robb)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 25

Top Venues

Journal of medicinal chemistry

Journal of chemical theory and computation

This page only lists publications with an associated author ORCID identifier.

Publications

Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry 67 (2) (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry 67 (16) (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry 67 (4) (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry 67 (4) (2024)
Finlay Clark, Graeme R Robb, Daniel J Cole, Julien Michel
Automated Adaptive Absolute Binding Free Energy Calculations. Journal of chemical theory and computation (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry 67 (16) (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry 67 (2) (2024)
Finlay Clark, Graeme R Robb, Daniel J Cole, Julien Michel
Comparison of Receptor-Ligand Restraint Schemes for Alchemical Absolute Binding Free Energy Calculations. Journal of chemical theory and computation (2023)
Jason G Kettle, Sharan K Bagal, Derek Barratt, Michael S Bodnarchuk, Scott Boyd, Erin Braybrooke, Jason Breed, Doyle J Cassar, Sabina Cosulich, Michael Davies, Nichola L Davies, Chao Deng, Andrew Eatherton, Laura Evans, Lyman J Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Miguel A Cortés González, Carine Guerot, Afreen Haider, Stephanie Harlfinger, Rachel Howells, Anne Jackson, Peter Johnström, Paul D Kemmitt, Alex Koers, Mikhail Kondrashov, Gillian M Lamont, Scott Lamont, Hilary J Lewis, Libin Liu, Megan Mylrea, Samuel Nash, Michael J Niedbala, Alison Peter, Christopher Phillips, Kurt Pike, Piotr Raubo, Graeme R Robb, Sarah Ross, Matthew G Sanders, Magnus Schou, Iain Simpson, Oliver Steward
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS G12C with Demonstrable CNS Penetration. Journal of medicinal chemistry (2023)
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Scott Boyd, Jason Breed, Rodrigo J Carbajo, Doyle J Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Nichola L Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Lyndsey Hanson, Stephanie Harlfinger, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Gillian Lamont, Scott Lamont, Hilary J Lewis, Libin Liu, Michael J Niedbala, Christopher Phillips, Radek Polanski, Piotr Raubo, Graeme R Robb, David M Robinson, Sarah Ross, Matthew G Sanders, Michael Tonge, Rebecca Whiteley, Stephen Wilkinson, Junsheng Yang, Wenman Zhang
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS G12C . Journal of medicinal chemistry 65 (9) (2022)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Correction to "Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles". Journal of medicinal chemistry 64 (5) (2021)
Claudia De Fusco, Marianne Schimpl, Ulf Börjesson, Tony Cheung, Iain Collie, Laura Evans, Priyanka Narasimhan, Christopher Stubbs, Mercedes Vazquez-Chantada, David J Wagner, Michael Grondine, Matthew G Sanders, Sharon Tentarelli, Elizabeth Underwood, Argyrides Argyrou, James M Smith, James T Lynch, Elisabetta Chiarparin, Graeme R Robb, Sharan K Bagal, James S Scott
Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model. Journal of medicinal chemistry 64 (10) (2021)
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Jason Breed, Rodrigo J Carbajo, Doyle J Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun M Fillery, Emma S Gleave, Frederick W Goldberg, Stephanie Harlfinger, Lyndsey Hanson, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Jennifer K Kingston, Scott Lamont, Hilary J Lewis, Songlei Li, Libin Liu, Derek Ogg, Christopher Phillips, Radek Polanski, Graeme R Robb, David Robinson, Sarah Ross, James M Smith, Michael Tonge, Rebecca Whiteley, Junsheng Yang, Longfei Zhang, Xiliang Zhao
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. Journal of medicinal chemistry 63 (9) (2020)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles. Journal of medicinal chemistry 62 (21) (2019)
Sébastien L Degorce, Rana Anjum, Andrew Bloecher, Rodrigo J Carbajo, Keith S Dillman, Lisa Drew, Christopher T Halsall, Eva M Lenz, Nicola A Lindsay, Michele F Mayo, Jennifer H Pink, Graeme R Robb, Alan Rosen, James S Scott, Yafeng Xue
Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma. Journal of medicinal chemistry 62 (21) (2019)

Graeme R Robb.css-eqlu8i{font-size:small;padding-left:4px;} (Graeme Robb)

Publication Activity (10 Years)

Top Topics

Top Venues

Graeme R Robb (Graeme Robb)