Raitis Bobrovs

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 22

Top Topics

Molecular Docking

Respiratory Syndrome Coronavirus

Top Venues

Nature communications

Molecules (Basel, Switzerland)

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Raitis Bobrovs, Jekaterina Bolsakova, Jhon Alexander Rodriguez Buitrago, Larisa Varaceva, Marija Skvorcova, Iveta Kanepe, Anastasija Rudnickiha, Emilio Parisini, Aigars Jirgensons
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors. PloS one 19 (4) (2024)
Raitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets, Indrek Teino, Aigars Jirgensons, Jason Matthews, Kristaps Jaudzems
Discovery and optimisation of pyrazolo[1,5- a ]pyrimidines as aryl hydrocarbon receptor antagonists. RSC medicinal chemistry (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Raitis Bobrovs, Jekaterina Bolsakova, Jhon Alexander Rodriguez Buitrago, Larisa Varaceva, Marija Skvorcova, Iveta Kanepe, Anastasija Rudnickiha, Emilio Parisini, Aigars Jirgensons
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors. PloS one 19 (4) (2024)
Vadims Kovada, Chrislaine Withers-Martinez, Raitis Bobrovs, Hele Na Ce Rule, Edgars Liepins, Solveiga Grinberga, Fiona Hackett, Christine R Collins, Agrita Kreicberga, María Belén Jiménez-Díaz, Iñigo Angulo-Barturen, Dace Rasina, Edgars Suna, Kristaps Jaudzems, Michael J Blackman, Aigars Jirgensons
Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. Journal of medicinal chemistry (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Jekaterina Bolsakova, Raitis Bobrovs, Larisa Varacheva, Anastasija Rudnickiha, Iveta Kanepe, Emilio Parisini, Aigars Jirgensons
Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library. ACS medicinal chemistry letters 15 (1) (2023)
Jekaterina Bolsakova, Raitis Bobrovs, Larisa Varacheva, Anastasija Rudnickiha, Iveta Kanepe, Emilio Parisini, Aigars Jirgensons
Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library. ACS medicinal chemistry letters 15 (1) (2023)
Raitis Bobrovs, Laura Drunka, Iveta Kanepe, Aigars Jirgensons, Amedeo Caflisch, Matteo Salvalaglio, Kristaps Jaudzems
Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors. Journal of chemical information and modeling (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Zigmantas Toleikis, Raitis Bobrovs, Agne Janoniene, Alons Lends, Mantas Ziaunys, Ieva Baronaite, Vytautas Petrauskas, Kristine Kitoka, Vytautas Smirnovas, Kristaps Jaudzems
Interactions between S100A9 and Alpha-Synuclein: Insight from NMR Spectroscopy. International journal of molecular sciences 23 (12) (2022)
Raitis Bobrovs, Emils Edgars Basens, Laura Drunka, Iveta Kanepe, Sofija Matisone, Karlis Kristofers Velins, Victor Andrianov, Gundars Leitis, Diana Zelencova-Gopejenko, Dace Rasina, Aigars Jirgensons, Kristaps Jaudzems
Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials. Journal of chemical information and modeling 62 (13) (2022)
Olga Bobileva, Raitis Bobrovs, Iveta Kaņepe, Liene Patetko, Gints Kalniņš, Mihails Šišovs, Anna L Bula, Solveiga Gri Nberga, Ma Rtiņš Borodušķis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Tars, Kristaps Jaudzems
Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate. ACS medicinal chemistry letters 12 (7) (2021)
Raitis Bobrovs, Iveta Kanepe, Nauris Narvaiss, Liene Patetko, Gints Kalnins, Mihails Sisovs, Anna L Bula, Solveiga Grinberga, Martins Boroduskis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Tars, Kristaps Jaudzems
Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening. Pharmaceuticals (Basel, Switzerland) 14 (12) (2021)
Jēkabs Fridmanis, Raitis Bobrovs, Kalvis Brangulis, Kaspars Tārs, Kristaps Jaudzems
Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein. Pathogens (Basel, Switzerland) 9 (10) (2020)
Kristaps Jaudzems, Viktorija Kurbatska, Atis Je Kabsons, Raitis Bobrovs, Zhanna Rudevica, Ainars Leonchiks
Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization. ACS infectious diseases 6 (2) (2019)
Raitis Bobrovs, Kristaps Jaudzems, Aigars Jirgensons
Exploiting Structural Dynamics To Design Open-Flap Inhibitors of Malarial Aspartic Proteases. Journal of medicinal chemistry 62 (20) (2019)