Haitao Yang

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Topics

Monoclonal Antibody

Structural Basis

Mycobacterium Tuberculosis

Top Venues

Nature communications

Nature structural & molecular biology

Signal transduction and targeted therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Mengmeng Lin, Xudong Zeng, Yinkai Duan, Zinan Yang, Yuanyuan Ma, Haitao Yang, Xiu-Na Yang, Xiang Liu
Molecular mechanism of ensitrelvir inhibiting SARS-CoV-2 main protease and its variants. Communications biology 6 (1) (2023)
Yinkai Duan, Hao Zhou, Xiang Liu, Sho Iketani, Mengmeng Lin, Xiaoyu Zhang, Qucheng Bian, Haofeng Wang, Haoran Sun, Seo Jung Hong, Bruce Culbertson, Hiroshi Mohri, Maria I Luck, Yan Zhu, Xiaoce Liu, Yuchi Lu, Xiu-Na Yang, Kailin Yang, Yosef Sabo, Alejandro Chavez, Stephen P Goff, Zihe Rao, David D Ho, Haitao Yang
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature (2023)
Yu Guo, Guangshun Zhang, Qi Yang, Xiaowei Xie, Yang Lu, Xuelian Cheng, Hui Wang, Jingxi Liang, Jielin Tang, Yuxin Gao, Hang Shang, Jun Dai, Yongxia Shi, Jiaxi Zhou, Jun Zhou, Hangtian Guo, Haitao Yang, Jianwei Qi, Lijun Liu, Shihui Ma, Biao Zhang, Qianyu Huo, Yi Xie, Junping Wu, Fang Dong, Song Zhang, Zhiyong Lou, Yan Gao, Zidan Song, Wenming Wang, Zixian Sun, Xiao Ming Yang, Dongsheng Xiong, Fengjiang Liu, Xinwen Chen, Caiying Zhu, Ximo Wang, Tao Cheng, Zihe Rao
Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nature communications 14 (1) (2023)
Hangtian Guo, Yixuan Yang, Tiantian Zhao, Yuchi Lu, Yan Gao, Tinghan Li, Hang Xiao, Xiaoyu Chu, Le Zheng, Wanting Li, Hao Cheng, Haibin Huang, Yang Liu, Yang Lou, Henry C Nguyen, Chao Wu, Yuxin Chen, Haitao Yang, Xiaoyun Ji
Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants. Communications biology 6 (1) (2023)
Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke W Guddat, Hongli Chen, Lei-Ke Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang
Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nature communications 14 (1) (2023)
Wen Z Yang, Hengchang Xie, Xiaosa Du, Qian Zhou, Yan Xiao, Zhengdong Zhao, Xiaoning Jia, Jianhui Xu, Wen Zhang, Shuang Cai, Zhangjie Li, Xin Fu, Rong Hua, Junhao Cai, Shuang Chang, Jing Sun, Hongbin Sun, Qingqing Xu, Xinyan Ni, Hongqing Tu, Ruimao Zheng, Xiao-Hong Xu, Hong Wang, Yu Fu, Liming Wang, Xi Li, Haitao Yang, Qiyuan Yao, Tian Yu, Qiwei Shen, Wei L Shen
A parabrachial-hypothalamic parallel circuit governs cold defense in mice. Nature communications 14 (1) (2023)
Wen Cui, Haojun Huang, Yinkai Duan, Zhi Luo, Haofeng Wang, Tenan Zhang, Henry C Nguyen, Wei Shen, Dan Su, Xi Li, Xiaoyun Ji, Haitao Yang, Wei Wang
Crystal structure of monkeypox H1 phosphatase, an antiviral drug target. Protein & cell 14 (6) (2023)
Wei Wang, Wen Cui, Haitao Yang
Toward an accurate mechanistic understanding of Wolbachia-induced cytoplasmic incompatibility. Environmental microbiology 24 (10) (2022)
Yao Zhao, Yan Zhu, Xiang Liu, Zhenming Jin, Yinkai Duan, Qi Zhang, Chengyao Wu, Lu Feng, Xiaoyu Du, Jinyi Zhao, Maolin Shao, Bing Zhang, Xiu-Na Yang, Li-Jie Wu, Xiaoyun Ji, Luke W Guddat, Kailin Yang, Zihe Rao, Haitao Yang
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 119 (16) (2022)
Shan Sun, Yan Gao, Xiaolin Yang, Xiu-Na Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Yuting Ran, Pengxuan Ren, Fang Bai, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein & cell (2022)
Sho Iketani, Hiroshi Mohri, Bruce Culbertson, Seo Jung Hong, Yinkai Duan, Maria I Luck, Medini K Annavajhala, Yicheng Guo, Zizhang Sheng, Anne-Catrin Uhlemann, Stephen P Goff, Yosef Sabo, Haitao Yang, Alejandro Chavez, David D Ho
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir. Nature (2022)
Haofeng Wang, Yunjie Xiao, Xia Chen, Mengwen Zhang, Guangxin Sun, Feng Wang, Lin Wang, Hanxiao Zhang, Xiaoyu Zhang, Xin Yang, Wenling Li, Yi Wei, Deqiang Yao, Bing Zhang, Jun Li, Wen Cui, Fenghua Wang, Cheng Chen, Wei L Shen, Dan Su, Fang Bai, Jinhai Huang, Sheng Ye, Lei Zhang, Xiaoyun Ji, Wei Wang, Zefang Wang, Mark Hochstrasser, Haitao Yang
Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue. Nature communications 13 (1) (2022)
Mengmeng Lin, Wen Cui, Hongliang Tian, Yan Zhang, Chen Chen, Xiaoyun Yang, Heng Chi, Zhongyu Mu, Cheng Chen, Zefang Wang, Xiaoyun Ji, Haitao Yang, Zhi Lin
Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. ACS infectious diseases 8 (1) (2021)
Kangsa Amporndanai, Xiaoli Meng, Weijuan Shang, Zhenming Jin, Michael Rogers, Yao Zhao, Zihe Rao, Zhi-Jie Liu, Haitao Yang, Lei-Ke Zhang, Paul M O'Neill, S Samar Hasnain
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nature communications 12 (1) (2021)
Haitao Yang, Zihe Rao
Structural biology of SARS-CoV-2 and implications for therapeutic development. Nature reviews. Microbiology 19 (11) (2021)
Yao Zhao, Chao Fang, Qi Zhang, Ruxue Zhang, Xiangbo Zhao, Yinkai Duan, Haofeng Wang, Yan Zhu, Lu Feng, Jinyi Zhao, Maolin Shao, Xiu-Na Yang, Lei-Ke Zhang, Chao Peng, Kailin Yang, Dawei Ma, Zihe Rao, Haitao Yang
Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332. Protein & cell (2021)
Tingting Li, Xiaojian Han, Chenjian Gu, Hangtian Guo, Huajun Zhang, Yingming Wang, Chao Hu, Kai Wang, Fengjiang Liu, Feiyang Luo, Yanan Zhang, Jie Hu, Wang Wang, Shenglong Li, Yanan Hao, Meiying Shen, Jingjing Huang, Yingyi Long, Shuyi Song, Ruixin Wu, Song Mu, Qian Chen, Fengxia Gao, Jianwei Wang, Shunhua Long, Luo Li, Yang Wu, Yan Gao, Wei Xu, Xia Cai, Di Qu, Zherui Zhang, Hongqing Zhang, Na Li, Qingzhu Gao, Guiji Zhang, Changlong He, Wei Wang, Xiaoyun Ji, Ni Tang, Zhenghong Yuan, You-Hua Xie, Haitao Yang, Bo Zhang, Ai-Long Huang, Ai-Shun Jin
Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nature communications 12 (1) (2021)
Wenhao Dai, Bing Zhang, Xia-Ming Jiang, Haixia Su, Jian Li, Yao Zhao, Xiong Xie, Zhenming Jin, Jingjing Peng, Fengjiang Liu, Chunpu Li, You Li, Fang Bai, Haofeng Wang, Xi Cheng, Xiaobo Cen, Shulei Hu, Xiuna Yang, Jiang Wang, Xiang Liu, Gengfu Xiao, Hualiang Jiang, Zihe Rao, Lei-Ke Zhang, Yechun Xu, Haitao Yang, Hong Liu
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science (New York, N.Y.) 368 (6497) (2020)
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng, Meiqin Liu, Yao Zhao, Bing Zhang, Xiaofeng Li, Leike Zhang, Chao Peng, Yinkai Duan, Jing Yu, Lin Wang, Kailin Yang, Fengjiang Liu, Rendi Jiang, Xinglou Yang, Tian You, Xiaoce Liu, Xiuna Yang, Fang Bai, Hong Liu, Xiang Liu, Luke W Guddat, Wenqing Xu, Gengfu Xiao, Chengfeng Qin, Zheng-Li Shi, Hualiang Jiang, Zihe Rao, Haitao Yang
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors. Nature 582 (7811) (2020)
Fengjiang Liu, Jingxi Liang, Bing Zhang, Yan Gao, Xiuna Yang, Tianyu Hu, Haitao Yang, Wenqing Xu, Luke W Guddat, Zihe Rao
Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Science advances 6 (44) (2020)
Lu Zhang, Yao Zhao, Yan Gao, Li-Jie Wu, Ruogu Gao, Qi Zhang, Yinan Wang, Chengyao Wu, Fangyu Wu, Sudagar S Gurcha, Natacha Veerapen, Sarah M Batt, Wei Zhao, Ling Qin, Xiuna Yang, Manfu Wang, Yan Zhu, Bing Zhang, Lijun Bi, Xian'en Zhang, Haitao Yang, Luke W Guddat, Wenqing Xu, Quan Wang, Jun Li, Gurdyal S Besra, Zihe Rao
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science (New York, N.Y.) 368 (6496) (2020)
Zhenming Jin, Yao Zhao, Yuan Sun, Bing Zhang, Haofeng Wang, Yan Wu, Yan Zhu, Chen Zhu, Tianyu Hu, Xiaoyu Du, Yinkai Duan, Jing Yu, Xiaobao Yang, Xiuna Yang, Kailin Yang, Xiang Liu, Luke W Guddat, Gengfu Xiao, Lei-Ke Zhang, Haitao Yang, Zihe Rao
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nature structural & molecular biology 27 (6) (2020)
Yan Gao, Liming Yan, Yucen Huang, Fengjiang Liu, Yao Zhao, Lin Cao, Tao Wang, Qianqian Sun, Zhenhua Ming, Lianqi Zhang, Ji Ge, Litao Zheng, Ying Zhang, Haofeng Wang, Yan Zhu, Chen Zhu, Tianyu Hu, Tian Hua, Bing Zhang, Xiuna Yang, Jun Li, Haitao Yang, Zhijie Liu, Wenqing Xu, Luke W Guddat, Quan Wang, Zhiyong Lou, Zihe Rao
Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science (New York, N.Y.) 368 (6492) (2020)
Wen Z Yang, Xiaosa Du, Wen Zhang, Cuicui Gao, Hengchang Xie, Yan Xiao, Xiaoning Jia, Jiashu Liu, Jianhui Xu, Xin Fu, Hongqing Tu, Xiaoyu Fu, Xinyan Ni, Miao He, Jiajun Yang, Hong Wang, Haitao Yang, Xiao-Hong Xu, Wei L Shen
Parabrachial neuron types categorically encode thermoregulation variables during heat defense. Science advances 6 (36) (2020)
Bo Zhang, Weichen Gao, Jiafang Piao, Yunjie Xiao, Bin Wang, Weipan Peng, Xiaoqun Gong, Zefang Wang, Haitao Yang, Jin Chang
Effective Bioactivity Retention of Low-Concentration Antibodies on HFBI-Modified Fluorescence ICTS for Sensitive and Rapid Detection of PSA. ACS applied materials & interfaces 10 (17) (2018)
Fenghua Wang, Cheng Chen, Kailin Yang, Yang Xu, Xiaomei Liu, Fan Gao, He Liu, Xia Chen, Qi Zhao, Xiang Liu, Yan Cai, Haitao Yang
Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus. Journal of medicinal chemistry 60 (7) (2017)