H Leighton Grimes (H L Grimes)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 54

Top Venues

Nature

Nature immunology

Nature communications

bioRxiv : the preprint server for biology

Cincinnati Children's Hospital Medical Center

University of Florida College of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Cincinnati Children's Hospital Medical Center Sep 02 2014

United States

Professor :: Immunobiology

Cincinnati Children's Hospital Medical Center - Sep 01 2014

United States

Associate Professor with Tenure :: Immunobiology

University of Louisville School of Medicine Jul 01 2005 - Oct 01 2005

United States

Associate Professor with Tenure :: Institute for Cellular Therapeutics

University of Louisville School of Medicine Dec 01 1998 - Jun 30 2005

United States

Assitant Professor :: Institute for Cellular Therapeutics

Drexel University College of Medicine May 01 1998 - Nov 01 1998

United States

Assistant Professor :: Institute for Cellular Therapeutics

Fox Chase Cancer Center Jul 01 1997 - May 01 1998

United States

Staff Scientist with Philip Tsichilis :: Cancer Biology

Fox Chase Cancer Center Jan 01 1993 - Jun 30 1997

United States

Postdoctoral Fellow with Philip N. Tsichlis :: Cancer Biology

Education History

University of Florida College of Medicine Sep 15 1985 - Dec 30 1992

United States

PHD :: Pathology

Loyola University New Orleans Sep 15 1979 - May 01 1985

United States

BSC :: Biological Sciences

Publications

Guangyuan Li, Shweta Mahajan, Siyuan Ma, Erin D Jeffery, Xuan Zhang, Anukana Bhattacharjee, Meenakshi Venkatasubramanian, Matthew T Weirauch, Emily R Miraldi, H Leighton Grimes, Gloria M Sheynkman, Tamara Tilburgs, Nathan Salomonis
Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. Science translational medicine 16 (730) (2024)
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Xiaoting Chen, Shanisha Gordon-Mitchell, Ariel Fromowitz, Kith Pradhan, David Shechter, Srabani Sahu, Diane Heiser, Peggy Scherle, Kashish Chetal, Aishwarya Kulkarni, Kasiani C Myers, Matthew T Weirauch, H Leighton Grimes, Daniel T Starczynowski, Amit K Verma, Nathan Salomonis
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation. bioRxiv : the preprint server for biology (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Xuan Zhang, Baobao Song, Maximillian J Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N Thompson, Bailee N Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N Bennett, Joshua Croteau, Ornella Salvatori, Melvin H Lye, Austin E Gillen, Craig T Jordan, Harinder Singh, Diane S Krause, Nathan Salomonis, H Leighton Grimes
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors. Nature immunology (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Guangyuan Li, Shweta Mahajan, Siyuan Ma, Erin D Jeffery, Xuan Zhang, Anukana Bhattacharjee, Meenakshi Venkatasubramanian, Matthew T Weirauch, Emily R Miraldi, H Leighton Grimes, Gloria M Sheynkman, Tamara Tilburgs, Nathan Salomonis
Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. Science translational medicine 16 (730) (2024)
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Xiaoting Chen, Shanisha Gordon-Mitchell, Ariel Fromowitz, Kith Pradhan, David Shechter, Srabani Sahu, Diane Heiser, Peggy Scherle, Kashish Chetal, Aishwarya Kulkarni, Kasiani C Myers, Matthew T Weirauch, H Leighton Grimes, Daniel T Starczynowski, Amit K Verma, Nathan Salomonis
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation. bioRxiv : the preprint server for biology (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature (2024)
Xuan Zhang, Baobao Song, Maximillian J Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N Thompson, Bailee N Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N Bennett, Joshua Croteau, Ornella Salvatori, Melvin H Lye, Austin E Gillen, Craig T Jordan, Harinder Singh, Diane S Krause, Nathan Salomonis, H Leighton Grimes
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors. Nature immunology 25 (4) (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Xuan Zhang, Baobao Song, Maximillian J Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N Thompson, Bailee N Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N Bennett, Joshua Croteau, Ornella Salvatori, Melvin H Lye, Austin E Gillen, Craig T Jordan, Harinder Singh, Diane S Krause, Nathan Salomonis, H Leighton Grimes
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors. Nature immunology 25 (4) (2024)
Qingqing Wu, Jizhou Zhang, Sumit Kumar, Siyu Shen, Morgan Kincaid, Courtney B Johnson, Yanan Sophia Zhang, Raphaël Turcotte, Clemens Alt, Kyoko Ito, Shelli Homan, Bryan E Sherman, Tzu-Yu Shao, Anastasiya Slaughter, Benjamin Weinhaus, Baobao Song, Marie-Dominique Filippi, H Leighton Grimes, Charles P Lin, Keisuke Ito, Sing Sing Way, J Matthew Kofron, Daniel Lucas
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature 627 (8005) (2024)
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Xiaoting Chen, Shanisha Gordon-Mitchell, Ariel Fromowitz, Kith Pradhan, David Shechter, Srabani Sahu, Diane Heiser, Peggy Scherle, Kashish Chetal, Aishwarya Kulkarni, Kasiani C Myers, Matthew T Weirauch, H Leighton Grimes, Daniel T Starczynowski, Amit K Verma, Nathan Salomonis
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation. bioRxiv : the preprint server for biology (2024)
Xuan Zhang, Baobao Song, Maximillian J Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N Thompson, Bailee N Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N Bennett, Joshua Croteau, Ornella Salvatori, Melvin H Lye, Austin E Gillen, Craig T Jordan, Harinder Singh, Diane S Krause, Nathan Salomonis, H Leighton Grimes
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors. Nature immunology 25 (4) (2024)
Xuan Zhang, Baobao Song, Maximillian J Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N Thompson, Bailee N Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N Bennett, Joshua Croteau, Ornella Salvatori, Melvin H Lye, Austin E Gillen, Craig T Jordan, Harinder Singh, Diane S Krause, Nathan Salomonis, H Leighton Grimes
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors. Nature immunology 25 (4) (2024)
Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra, Joshua Bennett, Krithika R Subramanian, Xiaoting Chen, Shanisha Gordon-Mitchell, Ariel Fromowitz, Kith Pradhan, David Shechter, Srabani Sahu, Diane Heiser, Peggy Scherle, Kashish Chetal, Aishwarya Kulkarni, Kasiani C Myers, Matthew T Weirauch, H Leighton Grimes, Daniel T Starczynowski, Amit K Verma, Nathan Salomonis
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation. bioRxiv : the preprint server for biology (2024)
Guangyuan Li, Baobao Song, Harinder Singh, V B Surya Prasath, H Leighton Grimes, Nathan Salomonis
Decision level integration of unimodal and multimodal single cell data with scTriangulate. Nature communications 14 (1) (2023)
Jayati Basu, Andre Olsson, Kyle Ferchen, Elizaveta K Titerina, Kashish Chetal, Emmanuelle Nicolas, Philip Czyzewicz, Dmitry Levchenko, Lu Ge, Xiang Hua, H Leighton Grimes, Nathan Salomonis, Dietmar J Kappes
ThPOK is a critical multifaceted regulator of myeloid lineage development. Nature immunology (2023)
Xuan Zhang, H Leighton Grimes
Improved detection of measurable residual disease in acute myeloid leukemia. Science advances 9 (38) (2023)
Guangyuan Li, Baobao Song, Harinder Singh, V B Surya Prasath, H Leighton Grimes, Nathan Salomonis
Decision level integration of unimodal and multimodal single cell data with scTriangulate. Nature communications 14 (1) (2023)
Guangyuan Li, Baobao Song, Harinder Singh, V B Surya Prasath, H Leighton Grimes, Nathan Salomonis
Decision level integration of unimodal and multimodal single cell data with scTriangulate. Nature communications 14 (1) (2023)
Michael Ozga, Deedra Nicolet, Krzysztof Mrózek, Ayse S Yilmaz, Jessica Kohlschmidt, Karilyn T Larkin, James S Blachly, Christopher C Oakes, Jill Buss, Christopher J Walker, Shelley J Orwick, Vindi Jurinovic, Maja Rothenberg-Thurley, Annika Dufour, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E Berdel, Bernhard J Woermann, Wolfgang Hiddemann, Jan Braess, Marion Subklewe, Karsten Spiekermann, Andrew J Carroll, William G Blum, Bayard L Powell, Jonathan E Kolitz, Joseph O Moore, Robert J Mayer, Richard A Larson, Geoffrey L Uy, Wendy Stock, Klaus H Metzeler, H Leighton Grimes, John C Byrd, Nathan Salomonis, Tobias Herold, Alice S Mims, Ann-Kathrin Eisfeld
Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG). Leukemia (2023)
Guangyuan Li, Baobao Song, Harinder Singh, V B Surya Prasath, H Leighton Grimes, Nathan Salomonis
Decision level integration of unimodal and multimodal single cell data with scTriangulate. Nature communications 14 (1) (2023)
Kyle Ferchen, Nathan Salomonis, H Leighton Grimes
pyInfinityFlow: optimized imputation and analysis of high-dimensional flow cytometry data for millions of cells. Bioinformatics (Oxford, England) 39 (5) (2023)
Kyle Ferchen, Nathan Salomonis, H Leighton Grimes
pyInfinityFlow: optimized imputation and analysis of high-dimensional flow cytometry data for millions of cells. Bioinformatics (Oxford, England) 39 (5) (2023)
Michael Solomon, Baobao Song, Vinothini Govindarajah, Samantha Good, Ashok Arasu, E Broderick Hinton, Kairavee Thakkar, James Bartram, Marie-Dominique Filippi, Jose A Cancelas, Nathan Salomonis, H Leighton Grimes, Damien Reynaud
Slow cycling and durable Flt3+ progenitors contribute to hematopoiesis under native conditions. The Journal of experimental medicine 221 (1) (2023)
Guangyuan Li, Baobao Song, Harinder Singh, V B Surya Prasath, H Leighton Grimes, Nathan Salomonis
Decision level integration of unimodal and multimodal single cell data with scTriangulate. Nature communications 14 (1) (2023)
Laurel Romano, Katie M Giger, Julien Papoin, David E Muench, Diamantis Konstantinidis, André Olsson, Katrina Schlum, Kashish Chetal, Joel Anne Chasis, Narla Mohandas, Betsy J Barnes, Yi Zheng, H Leighton Grimes, Nathan Salomonis, Lionel Blanc, Theodosia A Kalfa
Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis. Blood 140 (14) (2022)
Jayati Basu, Bernardo Sgarbi Reis, Suraj Peri, Jikun Zha, Xiang Hua, Lu Ge, Kyle Ferchen, Emmanuelle Nicolas, Philip Czyzewicz, Kathy Q Cai, Yinfei Tan, Juan I Fuxman Bass, Albertha J M Walhout, H Leighton Grimes, Sergei I Grivennikov, Daniel Mucida, Dietmar J Kappes
Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function. Nature immunology 22 (8) (2021)
Roberto Avelino, Roger Mulet-Lazaro, Marije Havermans, Remco Hoogenboezem, Leonie Smeenk, Nathan Salomonis, Rebekka K Schneider, Elwin J C Rombouts, Eric Bindels, H Leighton Grimes, Ruud Delwel
Induced cell-autonomous neutropenia systemically perturbs hematopoiesis in Cebpa enhancer-null mice. Blood advances (2021)
Jizhou Zhang, Qingqing Wu, Courtney B Johnson, Giang Pham, Jeremy M Kinder, Andre Olsson, Anastasiya Slaughter, Margot May, Benjamin Weinhaus, Angelo D'Alessandro, James Douglas Engel, Jean X Jiang, J Matthew Kofron, L Frank Huang, V B Surya Prasath, Sing Sing Way, Nathan Salomonis, H Leighton Grimes, Daniel Lucas
In situ mapping identifies distinct vascular niches for myelopoiesis. Nature 590 (7846) (2021)
Haobin Ye, Mohammad Minhajuddin, Anna Krug, Shanshan Pei, Chih-Hsing Chou, Rachel Culp-Hill, Jessica Ponder, Erik De Bloois, Björn Schniedewind, Maria L Amaya, Anagha Inguva, Brett M Stevens, Daniel A Pollyea, Uwe Christians, H Leighton Grimes, Angelo D'Alessandro, Craig T Jordan
The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG. Cancer discovery 11 (2) (2020)
Daniel Lucas, Nathan Salomonis, H Leighton Grimes
Unraveling bone marrow architecture. Nature cell biology 22 (1) (2020)
David E Muench, Andre Olsson, Kyle Ferchen, Giang Pham, Rachel A Serafin, Somchai Chutipongtanate, Pankaj Dwivedi, Baobao Song, Stuart Hay, Kashish Chetal, Lisa R Trump-Durbin, Jayati Mookerjee-Basu, Kejian Zhang, Jennifer C Yu, Carolyn Lutzko, Kasiani C Myers, Kristopher L Nazor, Kenneth D Greis, Dietmar J Kappes, Sing Sing Way, Nathan Salomonis, H Leighton Grimes
Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature 582 (7810) (2020)
Derek S Park, Afua A Akuffo, David E Muench, H Leighton Grimes, Pearlie K Epling-Burnette, Philip K Maini, Alexander R A Anderson, Michael B Bonsall
Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation. PLoS computational biology 15 (4) (2019)
Alberto Yáñez, Helen S Goodridge, H Leighton Grimes
Counting the cost of lineage decisions. Nature immunology 18 (8) (2019)
Catherine Lee, Vasilisa A Rudneva, Serap Erkek, Marc Zapatka, Lianne Q Chau, Silvia K Tacheva-Grigorova, Alexandra Garancher, Jessica M Rusert, Ozlem Aksoy, Robin Lea, Helai P Mohammad, Jianxun Wang, William A Weiss, H Leighton Grimes, Stefan M Pfister, Paul A Northcott, Robert J Wechsler-Reya
Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma. Nature communications 10 (1) (2019)
Cihangir Duy, Matthew R Teater, Francine E Garrett-Bakelman, Tak C Lee, Cem Meydan, Jacob L Glass, Meng Li, Johannes Christian Hellmuth, Helai P Mohammad, Kimberly N Smitheman, Alan H Shih, Omar Abdel-Wahab, Martin S Tallman, Monica L Guzman, David E Muench, H Leighton Grimes, Gail J Roboz, Ryan G Kruger, Caretha L Creasy, Elisabeth M Paietta, Ross L Levine, Martin Carroll, Ari M Melnick
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML. Cancer discovery 9 (7) (2019)
Emmalee R Adelman, Hsuan-Ting Huang, Alejandro Roisman, André Olsson, Antonio Colaprico, Tingting Qin, R Coleman Lindsley, Rafael Bejar, Nathan Salomonis, H Leighton Grimes, Maria E Figueroa
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia. Cancer discovery 9 (8) (2019)
Pankaj Dwivedi, David E Muench, Michael Wagner, Mohammad Azam, H Leighton Grimes, Kenneth D Greis
Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors. Scientific data 6 (1) (2019)
Yoshihiro Hayashi, Yue Zhang, Asumi Yokota, Xiaomei Yan, Jinqin Liu, Kwangmin Choi, Bing Li, Goro Sashida, Yanyan Peng, Zefeng Xu, Rui Huang, Lulu Zhang, George M Freudiger, Jingya Wang, Yunzhu Dong, Yile Zhou, Jieyu Wang, Lingyun Wu, Jiachen Bu, Aili Chen, Xinghui Zhao, Xiujuan Sun, Kashish Chetal, Andre Olsson, Miki Watanabe, Lindsey E Romick-Rosendale, Hironori Harada, Lee-Yung Shih, William Tse, James P Bridges, Michael A Caligiuri, Taosheng Huang, Yi Zheng, David P Witte, Qian-Fei Wang, Cheng-Kui Qu, Nathan Salomonis, H Leighton Grimes, Stephen D Nimer, Zhijian Xiao, Gang Huang
Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes. Cancer discovery 8 (11) (2018)
Pankaj Dwivedi, David E Muench, Michael Wagner, Mohammad Azam, H Leighton Grimes, Kenneth D Greis
Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. Leukemia 33 (1) (2018)
Sara E Meyer, David E Muench, Andrew M Rogers, Tess J Newkold, Emily Orr, Eric O'Brien, John P Perentesis, John G Doench, Ashish Lal, Patrick J Morris, Craig J Thomas, Judy Lieberman, Edwina McGlinn, Bruce J Aronow, Nathan Salomonis, H Leighton Grimes
miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential. The Journal of experimental medicine 215 (8) (2018)
David E Muench, Kyle Ferchen, Chinavenmeni S Velu, Kith Pradhan, Kashish Chetal, Xiaoting Chen, Matthew T Weirauch, Clemencia Colmenares, Amit Verma, Nathan Salomonis, H Leighton Grimes
SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness. Blood 132 (21) (2018)
J Bu, A Chen, X Yan, Fuhong He, Y Dong, Y Zhou, J He, D Zhan, P Lin, Y Hayashi, Y Sun, Y Zhang, Z Xiao, H Leighton Grimes, Q F Wang, G Huang
SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia. Leukemia 32 (4) (2017)
Benjamin Mizukawa, Eric O'Brien, Daniel C Moreira, Mark Wunderlich, Cindy L Hochstetler, Xin Duan, Wei Liu, Emily Orr, H Leighton Grimes, James C Mulloy, Yi Zheng
The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation. Blood 130 (11) (2017)
Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Tahir Latif, Ming Xu, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes, Mohammad Azam
Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia. Nature medicine 23 (4) (2017)
Jung-Mi Lee, Vinothini Govindarajah, Bryan Goddard, Ashwini Hinge, David E Muench, Marie-Dominique Filippi, Bruce J Aronow, Jose A Cancelas, Nathan Salomonis, H Leighton Grimes, Damien Reynaud
Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression. The Journal of experimental medicine 215 (2) (2017)
Jeffrey L Kurkewich, Justin Hansen, Nathan Klopfenstein, Helen Zhang, Christian Wood, Austin Boucher, Joseph Hickman, David E Muench, H Leighton Grimes, Richard Dahl
The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis. PLoS genetics 13 (7) (2017)
Jing Fang, Xiaona Liu, Lyndsey Bolanos, Brenden Barker, Carmela Rigolino, Agostino Cortelezzi, Esther N Oliva, Maria Cuzzola, H Leighton Grimes, Celia Fontanillo, Kakajan Komurov, Kyle MacBeth, Daniel T Starczynowski
A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes. Nature medicine 22 (7) (2016)
Kun-Po Li, Anke Fähnrich, Eron Roy, Carla M Cuda, H Leighton Grimes, Harris R Perlman, Kathrin Kalies, David A Hildeman
Temporal Expression of Bim Limits the Development of Agonist-Selected Thymocytes and Skews Their TCRβ Repertoire. Journal of immunology (Baltimore, Md. : 1950) 198 (1) (2016)

H Leighton Grimes.css-eqlu8i{font-size:small;padding-left:4px;} (H L Grimes)

Publication Activity (10 Years)

Top Topics

Top Venues

H Leighton Grimes (H L Grimes)