Haiyuan Yu

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 23

Top Topics

Protein Protein

Top Venues

bioRxiv : the preprint server for biology

Nature biotechnology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Yingying Zhang, Alden K Leung, Tian Qiu, Le Li, Junke Zhang, Shayne Wierbowski, James Booth, Haiyuan Yu
A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology. bioRxiv : the preprint server for biology (2023)
Dapeng Xiong, Junfei Zhao, Yunguang Qiu, Yadi Zhou, Dongjin Lee, Shobhita Gupta, Weiqiang Lu, Siqi Liang, Jin Joo Kang, Charis Eng, Joseph Loscalzo, Feixiong Cheng, Haiyuan Yu
3D structural human interactome reveals proteome-wide perturbations by disease mutations. bioRxiv : the preprint server for biology (2023)
Dapeng Xiong, Junfei Zhao, Yunguang Qiu, Yadi Zhou, Dongjin Lee, Shobhita Gupta, Weiqiang Lu, Siqi Liang, Jin Joo Kang, Charis Eng, Joseph Loscalzo, Feixiong Cheng, Haiyuan Yu
3D structural human interactome reveals proteome-wide perturbations by disease mutations. bioRxiv : the preprint server for biology (2023)
Xinbao Ding, Priti Singh, Kerry Schimenti, Tina N Tran, Robert Fragoza, Jimmaline Hardy, Kyle E Orwig, Marta Olszewska, Maciej K Kurpisz, Alexander N Yatsenko, Donald F Conrad, Haiyuan Yu, John C Schimenti
In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes. Proceedings of the National Academy of Sciences of the United States of America 120 (30) (2023)
Fahrettin Haczeyni, Sandra Steensels, Benjamin D Stein, James M Jordan, Le Li, Vincent Dartigue, Selenay S Sarklioglu, Jixuan Qiao, Xi K Zhou, Andrew J Dannenberg, Neil M Iyengar, Haiyuan Yu, Lewis C Cantley, Baran A Ersoy
Submitochondrial Protein Translocation Upon Stress Inhibits Thermogenic Energy Expenditure. bioRxiv : the preprint server for biology (2023)
Dapeng Xiong, Junfei Zhao, Yunguang Qiu, Yadi Zhou, Dongjin Lee, Shobhita Gupta, Weiqiang Lu, Siqi Liang, Jin Joo Kang, Charis Eng, Joseph Loscalzo, Feixiong Cheng, Haiyuan Yu
3D structural human interactome reveals proteome-wide perturbations by disease mutations. bioRxiv : the preprint server for biology (2023)
Fahrettin Haczeyni, Sandra Steensels, Benjamin D Stein, James M Jordan, Le Li, Vincent Dartigue, Selenay S Sarklioglu, Jixuan Qiao, Xi K Zhou, Andrew J Dannenberg, Neil M Iyengar, Haiyuan Yu, Lewis C Cantley, Baran A Ersoy
Submitochondrial Protein Translocation Upon Stress Inhibits Thermogenic Energy Expenditure. bioRxiv : the preprint server for biology (2023)
Alden King-Yung Leung, Li Yao, Haiyuan Yu
Functional genomic assays to annotate enhancer-promoter interactions genome wide. Human molecular genetics 31 (R1) (2022)
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne D Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, SavaÅŸ Tay, Glenn Randall, Peihui Wang, John T Lis, Cédric Feschotte, Serpil C Erzurum, Feixiong Cheng, Haiyuan Yu
A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets. Nature biotechnology (2022)
Li Yao, Jin Liang, Abdullah Ozer, Alden King-Yung Leung, John T Lis, Haiyuan Yu
A comparison of experimental assays and analytical methods for genome-wide identification of active enhancers. Nature biotechnology 40 (7) (2022)
Aaron M N Joiner, Ben P Phillips, Kumar Yugandhar, Ethan James Sanford, Marcus Bustamante Smolka, Haiyuan Yu, Elizabeth A Miller, J Christopher Fromme
Structural basis of TRAPPIII-mediated Rab1 activation. The EMBO journal 40 (12) (2021)
Siwei Chen, Yuan Liu, Yingying Zhang, Shayne D Wierbowski, Steven M Lipkin, Xiaomu Wei, Haiyuan Yu
A full-proteome, interaction-specific characterization of mutational hotspots across human cancers. Genome research 32 (1) (2021)
Shayne D Wierbowski, Siqi Liang, Yuan Liu, You Chen, Shagun Gupta, Nicole M Andre, Steven M Lipkin, Gary R Whittaker, Haiyuan Yu
A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbations. Nature methods 18 (12) (2021)
Michael C Lanz, Kumar Yugandhar, Shagun Gupta, Ethan J Sanford, Vitor M Faça, Stephanie Vega, Aaron M N Joiner, J Christopher Fromme, Haiyuan Yu, Marcus Bustamante Smolka
In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO reports 22 (2) (2021)
Priti Singh, Robert Fragoza, Cecilia S Blengini, Tina N Tran, Gianno Pannafino, Najla Al-Sweel, Kerry J Schimenti, Karen Schindler, Eric A Alani, Haiyuan Yu, John C Schimenti
Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging. Nature communications 12 (1) (2021)
Nathaniel D Tippens, Jin Liang, Alden King-Yung Leung, Shayne D Wierbowski, Abdullah Ozer, James G Booth, John T Lis, Haiyuan Yu
Transcription imparts architecture, function and logic to enhancer units. Nature genetics 52 (10) (2020)
Shayne D Wierbowski, Tommy V Vo, Pascal Falter-Braun, Timothy O Jobe, Lars H Kruse, Xiaomu Wei, Jin Liang, Michael J Meyer, Nurten Akturk, Christen A Rivera-Erick, Nicolas A Cordero, Mauricio I Paramo, Elnur E Shayhidin, Marta Bertolotti, Nathaniel D Tippens, Kazi Akther, Rita Sharma, Yuichi Katayose, Kourosh Salehi-Ashtiani, Tong Hao, Pamela C Ronald, Joseph R Ecker, Peter A Schweitzer, Shoshi Kikuchi, Hiroshi Mizuno, David E Hill, Marc Vidal, Gaurav D Moghe, Susan R McCouch, Haiyuan Yu
A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice. Proceedings of the National Academy of Sciences of the United States of America 117 (21) (2020)
Kumar Yugandhar, Jean-Philippe Pellois, Shayne D Wierbowski, Elnur Elyar Shayhidin, Haiyuan Yu
Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studies. Nature methods 17 (10) (2020)
Siwei Chen, Jiebiao Wang, A Ercument Cicek, Kathryn Roeder, Haiyuan Yu, Bernie Devlin
De novo missense variants disrupting protein-protein interactions affect risk for autism through gene co-expression and protein networks in neuronal cell types. Molecular autism 11 (1) (2020)
Sheng Qian, Siqi Liang, Haiyuan Yu
Leveraging genetic interactions for adverse drug-drug interaction prediction. PLoS computational biology 15 (5) (2019)
Robert Fragoza, Jishnu Das, Shayne D Wierbowski, Jin Liang, Tina N Tran, Siqi Liang, Juan F Beltran, Christen A Rivera-Erick, Kaixiong Ye, Jean-Philippe Pellois, Li Yao, Matthew Mort, Peter D Stenson, David N Cooper, Xiaomu Wei, Alon Keinan, John C Schimenti, Andrew G Clark, Haiyuan Yu
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. Nature communications 10 (1) (2019)
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Nature genetics 50 (7) (2018)
Michael J Meyer, Juan Felipe Beltrán, Siqi Liang, Robert Fragoza, Aaron Rumack, Jin Liang, Xiaomu Wei, Haiyuan Yu
Interactome INSIDER: a structural interactome browser for genomic studies. Nature methods 15 (2) (2018)