Hao-Jie Zhu

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Mass Spectrometry

Endothelial Cells

Top Venues

Journal of medicinal chemistry

Drug metabolism and disposition: the biological fate of chemicals

This page only lists publications with an associated author ORCID identifier.

Publications

Sun Min Jung, Hao-Jie Zhu
Regulation of human hydrolases and its implications in pharmacokinetics and pharmacodynamics. Drug metabolism and disposition: the biological fate of chemicals (2024)
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Yu-An Hang, Yueting Liu, Xingwu Zhou, Jingcheng Xiao, Xinwen Wang, Jason R Spence, Christiane E Wobus, Hao-Jie Zhu
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of medicinal chemistry 67 (9) (2024)
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Yu-An Hang, Yueting Liu, Xingwu Zhou, Jingcheng Xiao, Xinwen Wang, Jason R Spence, Christiane E Wobus, Hao-Jie Zhu
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of medicinal chemistry 67 (9) (2024)
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Yu-An Hang, Yueting Liu, Xingwu Zhou, Jingcheng Xiao, Xinwen Wang, Jason R Spence, Christiane E Wobus, Hao-Jie Zhu
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of medicinal chemistry 67 (9) (2024)
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Yu-An Hang, Yueting Liu, Xingwu Zhou, Jingcheng Xiao, Xinwen Wang, Jason R Spence, Christiane E Wobus, Hao-Jie Zhu
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of medicinal chemistry (2024)
Jiapeng Li, Daniel Macedo de Melo Jorge, Weiwen Wang, Shuxin Sun, Tristan Frum, Yu-An Hang, Yueting Liu, Xingwu Zhou, Jingcheng Xiao, Xinwen Wang, Jason R Spence, Christiane E Wobus, Hao-Jie Zhu
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung. Journal of medicinal chemistry 67 (9) (2024)
Logan S Smith, Xinwen Wang, Jian Shi, Bing He, Hao-Jie Zhu
Genome-Wide Association Study for the Genetic Determinants of Thiopurine Methyltransferase Protein Expression in Human Livers and Racial Differences. Pharmaceutical research (2023)
Varsha Bhatt-Mehta, Xinyue Jing, Xinwen Wang, Hao-Jie Zhu
Transplacental methadone exposure and risk of Neonatal Opioid Withdrawal Syndrome. Pharmacotherapy (2023)
Yueting Liu, Shuxin Sun, Jiapeng Li, Weiwen Wang, Hao-Jie Zhu
Cell-Dependent Activation of ProTide Prodrugs and Its Implications in Antiviral Studies. ACS pharmacology & translational science 6 (10) (2023)
Dylan Smith, Bing He, Jian Shi, Hao-Jie Zhu, Xinwen Wang
Novel independent trans- and cis-genetic variants associated with CYP2D6 expression and activity in human livers . Drug metabolism and disposition: the biological fate of chemicals (2023)
Xinwen Wang, Jian Shi, Hao-Jie Zhu
Targeted Absolute Protein Quantification Using SILAC Internal Standard and Full-Length Protein Calibrators (TAQSI). Methods in molecular biology (Clifton, N.J.) 2603 (2022)
Jiapeng Li, Yanling Xue, Xinwen Wang, Logan S Smith, Bing He, Shuhan Liu, Hao-Jie Zhu
Tissue- and cell-expression of druggable host proteins provide insights into repurposing drugs for COVID-19. Clinical and translational science (2022)
Lucy H Her, Jian Shi, Xinwen Wang, Bing He, Logan S Smith, Hui Jiang, Hao-Jie Zhu
Identification of regulatory variants of carboxylesterase 1 (CES1): A proof-of-concept study for the application of the Allele-Specific Protein Expression (ASPE) assay in identifying cis-acting regulatory genetic polymorphisms. Proteomics (2022)
Lucy H Her, Xinwen Wang, Jian Shi, Hee Jae Choi, Sun Min Jung, Logan S Smith, Audrey H Wu, Barry E Bleske, Hao-Jie Zhu
Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects. British journal of clinical pharmacology (2021)
Jian Shi, Jingcheng Xiao, Xinwen Wang, Sun Min Jung, Barry E Bleske, John S Markowitz, Kennerly S Patrick, Hao-Jie Zhu
Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof-of-Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism. Clinical pharmacology and therapeutics (2021)
Jiapeng Li, Jian Shi, Jingcheng Xiao, Lana Tran, Xinwen Wang, Hao-Jie Zhu
Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis. Drug metabolism and disposition: the biological fate of chemicals 50 (3) (2021)
Vikram M Shenoy, Brian R Thompson, Jian Shi, Hao-Jie Zhu, David E Smith, Gordon L Amidon
Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme. Molecular pharmaceutics 17 (5) (2020)
Jian Shi, Jingcheng Xiao, Jiapeng Li, Xinwen Wang, Lucy Her, Matthew J Sorensen, Hao-Jie Zhu
FRACPRED-2D-PRM: A Fraction Prediction Algorithm-Assisted 2D Liquid Chromatography-Based Parallel Reaction Monitoring-Mass Spectrometry Approach for Measuring Low-Abundance Proteins in Human Plasma. Proteomics 20 (24) (2020)
Bing He, Jian Shi, Xinwen Wang, Hui Jiang, Hao-Jie Zhu
Genome-wide pQTL analysis of protein expression regulatory networks in the human liver. BMC biology 18 (1) (2020)
Jian Shi, Xinwen Wang, Huaijun Zhu, Hui Jiang, Danxin Wang, Alexey Nesvizhskii, Hao-Jie Zhu
Response to the Comments on "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Proteomics Method". Journal of proteome research 18 (3) (2019)
Stephanie E Martinez, Jian Shi, Hao-Jie Zhu, Tania Perez Jimenez, Zhaohui Zhu, Michael H Court
Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability. Drug metabolism and disposition: the biological fate of chemicals 47 (11) (2019)