Herman O Sintim (H O Sintim)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 48

Top Topics

Multiple Myeloma

Biofilm Formation

Staphylococcus Aureus

Multidrug Resistant

Top Venues

RSC medicinal chemistry

ACS infectious diseases

Chembiochem : a European journal of chemical biology

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Simpa K Yeboah, Herman O Sintim
PDE-stable 2'3'-cGAMP analogues, containing 5'-S-phosphorothioester linkage, as STING agonists. RSC medicinal chemistry 15 (5) (2024)
Simpa K Yeboah, Herman O Sintim
PDE-stable 2'3'-cGAMP analogues, containing 5'-S-phosphorothioester linkage, as STING agonists. RSC medicinal chemistry 15 (5) (2024)
Simpa K Yeboah, Abdulai Zigli, Herman O Sintim
2',4'-LNA-Functionalized 5'-S-Phosphorothioester CDNs as STING Agonists. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Simpa K Yeboah, Abdulai Zigli, Herman O Sintim
2',4'-LNA-Functionalized 5'-S-Phosphorothioester CDNs as STING Agonists. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Simpa K Yeboah, Abdulai Zigli, Herman O Sintim
2',4'-LNA-Functionalized 5'-S-Phosphorothioester CDNs as STING Agonists. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Simpa K Yeboah, Abdulai Zigli, Herman O Sintim
2',4'-LNA-Functionalized 5'-S-Phosphorothioester CDNs as STING Agonists. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Allison L Kempen, Nickolas R Brauer, Herman O Sintim
Dual FLT3/haspin kinase inhibitor based on 3 H -pyrazolo[4,3- f ]quinoline scaffold with activities against acute myeloid leukemia. RSC medicinal chemistry 14 (9) (2023)
Ujjwol Khatri, Neetu Dayal, Xueqing Hu, Elizabeth Larocque, Nimishetti Naganna, Tao Shen, Xuan Liu, Frederick W Holtsberg, M Javad Aman, Herman O Sintim, Jie Wu
Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors. Molecular cancer therapeutics (2023)
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey, Robert K Ernst, Roberta J Melander, Roberta J Melander, Herman O Sintim
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS infectious diseases 9 (2) (2023)
Christopher Vennard, Temitope Oropo, Herman O Sintim
Engineered Vancomycin, with Increased Interactions with Peptidoglycan Stem Peptide, Conquers Non-tuberculosis Mycobacteria. Journal of medicinal chemistry (2023)
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey, Robert K Ernst, Roberta J Melander, Roberta J Melander, Herman O Sintim
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS infectious diseases 9 (2) (2023)
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey, Robert K Ernst, Roberta J Melander, Roberta J Melander, Herman O Sintim
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS infectious diseases 9 (2) (2023)
Desmond Akwata, Allison L Kempen, Jones Lamptey, Neetu Dayal, Nickolas R Brauer, Herman O Sintim
Discovery of imidazo[1,2- b ]pyridazine-containing TAK1 kinase inhibitors with excellent activities against multiple myeloma. RSC medicinal chemistry 15 (1) (2023)
Wilson W S Ong, Neetu Dayal, Riddhi Chaudhuri, Jones Lamptey, Herman O Sintim
STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction. RSC medicinal chemistry 14 (6) (2023)
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey, Robert K Ernst, Roberta J Melander, Roberta J Melander, Herman O Sintim
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS infectious diseases 9 (2) (2023)
Desmond Akwata, Allison L Kempen, Jones Lamptey, Neetu Dayal, Nickolas R Brauer, Herman O Sintim
Discovery of imidazo[1,2- b ]pyridazine-containing TAK1 kinase inhibitors with excellent activities against multiple myeloma. RSC medicinal chemistry 15 (1) (2023)
Wilson W S Ong, Neetu Dayal, Riddhi Chaudhuri, Jones Lamptey, Herman O Sintim
STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction. RSC medicinal chemistry 14 (6) (2023)
Kenneth I Onyedibe, Ansley M Nemeth, Neetu Dayal, Richard D Smith, Jones Lamptey, Robert K Ernst, Roberta J Melander, Roberta J Melander, Herman O Sintim
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS infectious diseases (2023)
George A Naclerio, Kenneth I Onyedibe, Caroline W Karanja, Uma K Aryal, Herman O Sintim
Comparative Studies to Uncover Mechanisms of Action of N -(1,3,4-Oxadiazol-2-yl)benzamide Containing Antibacterial Agents. ACS infectious diseases 8 (4) (2022)
Christopher Vennard, Herman O Sintim
An Expanding Role of 2',3'-Cyclic Nucleotide Monophosphates in Bacteria. ACS central science 8 (11) (2022)
George A Naclerio, Nader S Abutaleb, Kenneth I Onyedibe, Caroline Karanja, Hassan E Eldesouky, Hsin-Wen Liang, Alexandra Dieterly, Uma K Aryal, Tiffany Lyle, Mohamed N Seleem, Herman O Sintim
Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic. Journal of medicinal chemistry 65 (9) (2022)
Piao Hu, Khanh Loan Ly, Le P H Pham, Alex E Pottash, Kathleen Sheridan, Hsuan-Chen Wu, Chen-Yu Tsao, David Quan, William E Bentley, Gary W Rubloff, Herman O Sintim, Xiaolong Luo
Bacterial chemotaxis in static gradients quantified in a biopolymer membrane-integrated microfluidic platform. Lab on a chip 22 (17) (2022)
George A Naclerio, Nader S Abutaleb, Marwa Alhashimi, Mohamed N Seleem, Herman O Sintim
N-(1,3,4-Oxadiazol-2-yl)Benzamides as Antibacterial Agents against Neisseria gonorrhoeae. International journal of molecular sciences 22 (5) (2021)
Caroline W Karanja, Kofi S Yeboah, Herman O Sintim
Identification of a Mycobacterium tuberculosis Cyclic Dinucleotide Phosphodiesterase Inhibitor. ACS infectious diseases 7 (2) (2021)
Jinjia Xu, Jian Xu, Haesoo Moon, Herman O Sintim, Hyowon Hugh Lee
Zwitterionic liquid crystalline polythiophene as an antibiofouling biomaterial. Journal of materials chemistry. B 9 (2) (2021)
Kenneth I Onyedibe, Samira Elmanfi, Uma K Aryal, Eija Könönen, Ulvi Kahraman Gursoy, Herman O Sintim
Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP. Journal of oral microbiology 14 (1) (2021)
Kenneth I Onyedibe, Neetu Dayal, Herman O Sintim
SF5- and SCF3-substituted tetrahydroquinoline compounds as potent bactericidal agents against multidrug-resistant persister Gram-positive bacteria. RSC medicinal chemistry 12 (11) (2021)
Modi Wang, Riddhi Chaudhuri, Wilson W S Ong, Herman O Sintim
c-di-GMP Induces COX-2 Expression in Macrophages in a STING-Independent Manner. ACS chemical biology 16 (9) (2021)
George A Naclerio, Herman O Sintim
Starving Bacteria of Iron: A Potential Strategy to Disperse Bacterial Biofilms. Journal of medicinal chemistry 64 (11) (2021)
George A Naclerio, Kenneth I Onyedibe, Herman O Sintim
Lipoteichoic Acid Biosynthesis Inhibitors as Potent Inhibitors of S. aureus and E. faecalis Growth and Biofilm Formation. Molecules (Basel, Switzerland) 25 (10) (2020)
Jian Xu, Haesoo Moon, Jinjia Xu, Jongcheon Lim, Thomas Fischer, Helen A McNally, Herman O Sintim, Hyowon Hugh Lee
One-Step Large-Scale Nanotexturing of Nonplanar PTFE Surfaces to Induce Bactericidal and Anti-inflammatory Properties. ACS applied materials & interfaces 12 (24) (2020)
George A Naclerio, Herman O Sintim
Multiple ways to kill bacteria via inhibiting novel cell wall or membrane targets. Future medicinal chemistry 12 (13) (2020)
Caroline W Karanja, Kofi S Yeboah, Wilson W S Ong, Herman O Sintim
A STING-based fluorescent polarization assay for monitoring activities of cyclic dinucleotide metabolizing enzymes. RSC chemical biology 2 (1) (2020)
George A Naclerio, Nader S Abutaleb, Daoyi Li, Mohamed N Seleem, Herman O Sintim
Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo. Journal of medicinal chemistry 63 (20) (2020)
George A Naclerio, Caroline W Karanja, Clement Opoku-Temeng, Herman O Sintim
Antibacterial Small Molecules That Potently Inhibit Staphylococcus aureus Lipoteichoic Acid Biosynthesis. ChemMedChem 14 (10) (2019)
Sarah M Robinson, Zuliang Shen, Jon R Askim, Christopher B Montgomery, Herman O Sintim, Steve Semancik
Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform. Biosensors 9 (2) (2019)
Herman O Sintim, Hamad H Al Mamari, Hasanain A A Almohseni, Younes Fegheh-Hassanpour, David M Hodgson
Alkylation of lithiated dimethyl tartrate acetonide with unactivated alkyl halides and application to an asymmetric synthesis of the 2,8-dioxabicyclo[3.2.1]octane core of squalestatins/zaragozic acids. Beilstein journal of organic chemistry 15 (2019)
George A Naclerio, Nader S Abutaleb, Kenneth I Onyedibe, Mohamed N Seleem, Herman O Sintim
Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. RSC medicinal chemistry 11 (1) (2019)
Neetu Dayal, Clement Opoku-Temeng, Haroon Mohammad, Nader S Abutaleb, Delmis Hernandez, Kenneth Ikenna Onyedibe, Modi Wang, Matthias Zeller, Mohamed N Seleem, Herman O Sintim
Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov-Doebner Reactions. ACS infectious diseases 5 (11) (2019)
Herman O Sintim, Clinton G Mikek, Modi Wang, Moloud A Sooreshjani
Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules. MedChemComm 10 (12) (2019)
Jung-Hye Ha, Pricila Hauk, Kun Cho, Yumi Eo, Xiaochu Ma, Kristina Stephens, Soyoung Cha, Migyeong Jeong, Jeong-Yong Suh, Herman O Sintim, William E Bentley, Kyoung Seok Ryu
Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr. Science advances 4 (6) (2018)
Samira Elmanfi, X Ma, Herman O Sintim, E Könönen, S Syrjänen, Ulvi Kahraman Gursoy
Quorum-sensing molecule dihydroxy-2,3-pentanedione and its analogs as regulators of epithelial integrity. Journal of periodontal research 53 (3) (2018)
Younes Fegheh-Hassanpour, Tanzeel Arif, Herman O Sintim, Hamad H Al Mamari, David M Hodgson
Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Organic letters 20 (17) (2018)
Samira Elmanfi, Jie Zhou, Herman O Sintim, Eija Könönen, Mervi Gursoy, Ulvi Kahraman Gursoy
Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides. Journal of oral microbiology 11 (1) (2018)
Elizabeth A Larocque, N Naganna, Clement Opoku-Temeng, Alyssa M Lambrecht, Herman O Sintim
Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase. ChemMedChem 13 (12) (2018)
Moloud Aflaki Sooreshjani, Ulvi Kahraman Gursoy, Uma K Aryal, Herman O Sintim
Proteomic analysis of RAW macrophages treated with cGAMP or c-di-GMP reveals differentially activated cellular pathways. RSC advances 8 (64) (2018)
Younes Fegheh-Hassanpour, Tanzeel Arif, Herman O Sintim, Hamad H Al Mamari, David M Hodgson
Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Organic letters 19 (13) (2017)
Yue Zheng, Genichiro Tsuji, Clement Opoku-Temeng, Herman O Sintim
Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative. Chemical science 7 (9) (2016)