Mohamed N Seleem

Loop profile Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 66

Top Venues

ACS infectious diseases

Journal of medicinal chemistry

Antimicrobial agents and chemotherapy

PloS one

Virginia Tech

Virginia Tech (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Virginia Tech Jun 01 2020

United States

Tyler and Frances Young Chair in Bacteriology :: Biomedical Sciences and Pathobiology

Purdue University Jan 03 2011 - May 31 2020

United States

Professor :: Comparative Pathobiology

Education History

Virginia Tech

United States

PHD :: Biomedical Sciences and Pathobiology

Assiut University Faculty of Veterinary Medicine

Egypt

MSC :: Animal Hygiene and Zoonosis

Publications

Alessandro Bonardi, Alessio Nocentini, Simone Giovannuzzi, Niccolò Paoletti, Andrea Ammara, Silvia Bua, Nader S Abutaleb, Abdallah S Abdelsattar, Clemente Capasso, Paola Gratteri, Daniel P Flaherty, Mohamed N Seleem, Claudiu T Supuran
Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae . Journal of medicinal chemistry (2024)
Andrew Encinas, Reena Blade, Nader S Abutaleb, Ahmed A Abouelkhair, Colin Caine, Mohamed N Seleem, Jean Chmielewski
Effects of Rigidity and Configuration of Charged Moieties within Cationic Amphiphilic Polyproline Helices on Cell Penetration and Antibiotic Activity. ACS infectious diseases 10 (8) (2024)
Alessandro Bonardi, Alessio Nocentini, Simone Giovannuzzi, Niccolò Paoletti, Andrea Ammara, Silvia Bua, Nader S Abutaleb, Abdallah S Abdelsattar, Clemente Capasso, Paola Gratteri, Daniel P Flaherty, Mohamed N Seleem, Claudiu T Supuran
Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae . Journal of medicinal chemistry 67 (11) (2024)
Molly S Youse, Nader S Abutaleb, Alessio Nocentini, Abdallah S Abdelsattar, Farman Ali, Claudiu T Supuran, Mohamed N Seleem, Daniel P Flaherty
Optimization of Ethoxzolamide Analogs with Improved Pharmacokinetic Properties for In Vivo Efficacy against Neisseria gonorrhoeae . Journal of medicinal chemistry (2024)
Nour M Alkashef, Mohamed N Seleem
Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis. PloS one 19 (8) (2024)
Ahmed A Abouelkhair, Mohamed N Seleem
Exploring novel microbial metabolites and drugs for inhibiting Clostridioides difficile . mSphere 9 (7) (2024)
Ahmed A Abouelkhair, Mohamed N Seleem
Exploring novel microbial metabolites and drugs for inhibiting Clostridioides difficile . mSphere (2024)
Alessandro Bonardi, Alessio Nocentini, Simone Giovannuzzi, Niccolò Paoletti, Andrea Ammara, Silvia Bua, Nader S Abutaleb, Abdallah S Abdelsattar, Clemente Capasso, Paola Gratteri, Daniel P Flaherty, Mohamed N Seleem, Claudiu T Supuran
Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae . Journal of medicinal chemistry (2024)
Andrew Encinas, Reena Blade, Nader S Abutaleb, Ahmed A Abouelkhair, Colin Caine, Mohamed N Seleem, Jean Chmielewski
Effects of Rigidity and Configuration of Charged Moieties within Cationic Amphiphilic Polyproline Helices on Cell Penetration and Antibiotic Activity. ACS infectious diseases (2024)
Nour M Alkashef, Mohamed N Seleem
Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis. PloS one 19 (8) (2024)
Ahmed A Abouelkhair, Mohamed N Seleem
Exploring novel microbial metabolites and drugs for inhibiting Clostridioides difficile . mSphere 9 (7) (2024)
Ahmed A Abouelkhair, Mohamed N Seleem
Exploring novel microbial metabolites and drugs for inhibiting Clostridioides difficile . mSphere 9 (7) (2024)
Nour M Alkashef, Mohamed N Seleem
Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis. PloS one 19 (8) (2024)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy 67 (5) (2023)
Meng Zhang, Pu-Ting Dong, Hassan E Eldesouky, Yuewei Zhan, Haonan Lin, Zian Wang, Ehab A Salama, Sebastian Jusuf, Cheng Zong, Zhicong Chen, Mohamed N Seleem, Ji-Xin Cheng
Fingerprint Stimulated Raman Scattering Imaging Unveils Ergosteryl Ester as a Metabolic Signature of Azole-Resistant Candida albicans . Analytical chemistry (2023)
Babatomiwa Kikiowo, Aloka B Bandara, Nader S Abutaleb, Mohamed N Seleem
Colonization efficiency of multidrug-resistant Neisseria gonorrhoeae in a female mouse model. Pathogens and disease (2023)
Rusha Pal, Mohamed N Seleem
Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile . Microbiology spectrum (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy 67 (5) (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy 67 (5) (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy (2023)
Nader S Abutaleb, Annadka Shrinidhi, Aloka B Bandara, Mohamed N Seleem, Daniel P Flaherty
Evaluation of 1,3,4-Thiadiazole Carbonic Anhydrase Inhibitors for Gut Decolonization of Vancomycin-Resistant Enterococci. ACS medicinal chemistry letters 14 (4) (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy 67 (5) (2023)
Yehia Elgammal, Ehab A Salama, Mohamed N Seleem
Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial agents and chemotherapy (2023)
Alexander Roth, Akshay Krishnakumar, Robyn R McCain, Murali Kanaan Maruthamuthu, MacKenzie McIntosh, Yue Xiang Chen, Abigail D Cox, Amber S Hopf Jannasch, Juliane Nguyen, Mohamed N Seleem, Rahim Rahimi
Biocompatibility and Safety Assessment of Combined Topical Ozone and Antibiotics for Treatment of Infected Wounds. ACS biomaterials science & engineering (2023)
Ahmed E M Elhassanny, Nader S Abutaleb, Mohamed N Seleem
Auranofin exerts antibacterial activity against Neisseria gonorrhoeae in a female mouse model of genital tract infection. PloS one 17 (4) (2022)
Anil Kumar Marapaka, Alessio Nocentini, Molly S Youse, Weiwei An, Katrina J Holly, Chittaranjan Das, Ravi Yadav, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty
Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae α-Carbonic Anhydrase. ACS medicinal chemistry letters 14 (1) (2022)
Rusha Pal, Ahmad I M Athamneh, Riddhi Deshpande, Jose A R Ramirez, Kayode T Adu, Pushpanathan Muthuirulan, Shrikant Pawar, Manuele Biazzo, Yiorgos Apidianakis, Ulrik Kraemer Sundekilde, Cesar de la Fuente-Nunez, Mark G Martens, George P Tegos, Mohamed N Seleem
Probiotics: insights and new opportunities for Clostridioides difficile intervention. Critical reviews in microbiology (2022)
Hanzada T Nour El-Din, Mohamed M Elsebaie, Nader S Abutaleb, Ahmed M Kotb, Ahmed S Attia, Mohamed N Seleem, Abdelrahman S Mayhoub
Expanding the structure-activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents. RSC medicinal chemistry 14 (2) (2022)
Hanzada T Nour El-Din, Mohamed M Elsebaie, Nader S Abutaleb, Ahmed M Kotb, Ahmed S Attia, Mohamed N Seleem, Abdelrahman S Mayhoub
Expanding the structure-activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents. RSC medicinal chemistry 14 (2) (2022)
Simone Giovannuzzi, Nader S Abutaleb, Chad S Hewitt, Fabrizio Carta, Alessio Nocentini, Mohamed N Seleem, Daniel P Flaherty, Claudiu T Supuran
Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae . Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Nader S Abutaleb, Ahmed E M Elhassanny, Alessio Nocentini, Chad S Hewitt, Ahmed Elkashif, Bruce R Cooper, Claudiu T Supuran, Mohamed N Seleem, Daniel P Flaherty
Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae . Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Anil Kumar Marapaka, Alessio Nocentini, Molly S Youse, Weiwei An, Katrina J Holly, Chittaranjan Das, Ravi Yadav, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty
Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae α-Carbonic Anhydrase. ACS medicinal chemistry letters 14 (1) (2022)
George A Naclerio, Nader S Abutaleb, Kenneth I Onyedibe, Caroline Karanja, Hassan E Eldesouky, Hsin-Wen Liang, Alexandra Dieterly, Uma K Aryal, Tiffany Lyle, Mohamed N Seleem, Herman O Sintim
Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic. Journal of medicinal chemistry 65 (9) (2022)
Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty
Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Rusha Pal, Mohamed N Seleem
Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo. PloS one 17 (8) (2022)
Ian Woodhouse, Sina Nejati, Vidhya Selvamani, Hongjie Jiang, Shirisha Chittiboyina, Jesse Grant, Zeynep Mutlu, Jose Waimin, Nader S Abutaleb, Mohamed N Seleem, Rahim Rahimi
Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication. ACS applied bio materials 4 (7) (2021)
Hassan E Eldesouky, Nadia Atallah Lanman, Tony R Hazbun, Mohamed N Seleem
Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs. Virulence 11 (1) (2021)
Nader S Abutaleb, Ahmed Elkashif, Daniel P Flaherty, Mohamed N Seleem
In Vivo Antibacterial Activity of Acetazolamide. Antimicrobial agents and chemotherapy 65 (4) (2021)
Simseok A Yuk, Hyungjun Kim, Nader S Abutaleb, Alexandra M Dieterly, Maie S Taha, Michael D Tsifansky, L Tiffany Lyle, Mohamed N Seleem, Yoon Yeo
Nanocapsules modify membrane interaction of polymyxin B to enable safe systemic therapy of Gram-negative sepsis. Science advances 7 (32) (2021)
Chad S Hewitt, Nader S Abutaleb, Ahmed E M Elhassanny, Alessio Nocentini, Xufeng Cao, Devon P Amos, Molly S Youse, Katrina J Holly, Anil Kumar Marapaka, Weiwei An, Jatinder Kaur, Aaron D Krabill, Ahmed Elkashif, Yehia Elgammal, Amanda L Graboski, Claudiu T Supuran, Mohamed N Seleem, Daniel P Flaherty
Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae. ACS infectious diseases 7 (7) (2021)
Daniel P Flaherty, Mohamed N Seleem, Claudiu T Supuran
Bacterial carbonic anhydrases: underexploited antibacterial therapeutic targets. Future medicinal chemistry 13 (19) (2021)
Chandradhish Ghosh, Ahmed Hassan AbdelKhalek, Haroon Mohammad, Mohamed N Seleem, Jayanta Haldar
Aryl-alkyl-lysines: Novel agents for treatment of C. difficile infection. Scientific reports 10 (1) (2020)
Hassan E Eldesouky, Ehab A Salama, Nadia A Lanman, Tony R Hazbun, Mohamed N Seleem
Potent Synergistic Interactions between Lopinavir and Azole Antifungal Drugs against Emerging Multidrug-Resistant Candida auris. Antimicrobial agents and chemotherapy 65 (1) (2020)
Jatinder Kaur, Xufeng Cao, Nader S Abutaleb, Ahmed Elkashif, Amanda L Graboski, Aaron D Krabill, Ahmed Hassan AbdelKhalek, Weiwei An, Atul Bhardwaj, Mohamed N Seleem, Daniel P Flaherty
Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus. Journal of medicinal chemistry 63 (17) (2020)
Hassan E Eldesouky, Ehab A Salama, Tony R Hazbun, Abdelrahman S Mayhoub, Mohamed N Seleem
Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities. Scientific reports 10 (1) (2020)
Mohamed Hagras, Nader S Abutaleb, Noha M Elhosseiny, Tamer M Abdelghany, Mariam Omara, Mohamed M Elsebaie, Marwa Alhashimi, Allison B Norvil, Mark I Gutay, Humaira Gowher, Ahmed S Attia, Mohamed N Seleem, Abdelrahman S Mayhoub
Development of Biphenylthiazoles Exhibiting Improved Pharmacokinetics and Potent Activity Against Intracellular Staphylococcus aureus. ACS infectious diseases 6 (11) (2020)
Thomas A Dietsche, Hassan E Eldesouky, Samantha M Zeiders, Mohamed N Seleem, Jean Chmielewski
Targeting Intracellular Pathogenic Bacteria Through N-Terminal Modification of Cationic Amphiphilic Polyproline Helices. The Journal of organic chemistry 85 (11) (2020)
Ahmed Hassan AbdelKhalek, Haroon Mohammad, Abdelrahman S Mayhoub, Mohamed N Seleem
Screening for potent and selective anticlostridial leads among FDA-approved drugs. The Journal of antibiotics 73 (6) (2020)
Junfeng Song, Satish R Malwal, Noman Baig, Lici A Schurig-Briccio, Zijun Gao, Girija S Vaidya, Kailing Yang, Nader S Abutaleb, Mohamed N Seleem, Robert B Gennis, Taras V Pogorelov, Eric Oldfield, Xinxin Feng
Discovery of Prenyltransferase Inhibitors with In Vitro and In Vivo Antibacterial Activity. ACS infectious diseases 6 (11) (2020)
George A Naclerio, Nader S Abutaleb, Daoyi Li, Mohamed N Seleem, Herman O Sintim
Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo. Journal of medicinal chemistry 63 (20) (2020)
Haroon Mohammad, Hassan E Eldesouky, Tony Hazbun, Abdelrahman S Mayhoub, Mohamed N Seleem
Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris. Scientific reports 9 (1) (2019)
Xuwei Shao, Ahmed AbdelKhalek, Nader S Abutaleb, Uday Kiran Velagapudi, Sabesan Yoganathan, Mohamed N Seleem, Tanaji T Talele
Chemical Space Exploration around Thieno[3,2-d]pyrimidin-4(3H)-one Scaffold Led to a Novel Class of Highly Active Clostridium difficile Inhibitors. Journal of medicinal chemistry 62 (21) (2019)
George A Naclerio, Nader S Abutaleb, Kenneth I Onyedibe, Mohamed N Seleem, Herman O Sintim
Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. RSC medicinal chemistry 11 (1) (2019)
Ali Hammad, Nader S Abutaleb, Mohamed M Elsebaei, Allison B Norvil, Mohamed Alswah, Alsagher O Ali, Jelan A Abdel-Aleem, Abdelaziz Alattar, Sammar A Bayoumi, Humaira Gowher, Mohamed N Seleem, Abdelrahman S Mayhoub
From Phenylthiazoles to Phenylpyrazoles: Broadening the Antibacterial Spectrum toward Carbapenem-Resistant Bacteria. Journal of medicinal chemistry 62 (17) (2019)
Neetu Dayal, Clement Opoku-Temeng, Haroon Mohammad, Nader S Abutaleb, Delmis Hernandez, Kenneth Ikenna Onyedibe, Modi Wang, Matthias Zeller, Mohamed N Seleem, Herman O Sintim
Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov-Doebner Reactions. ACS infectious diseases 5 (11) (2019)
Ahmed Mancy, Nader S Abutaleb, Mohamed M Elsebaie, Abdullah Y Saad, Ahmed Kotb, Alsagher O Ali, Jelan A Abdel-Aleem, Haroon Mohammad, Mohamed N Seleem, Abdelrahman S Mayhoub
Balancing Physicochemical Properties of Phenylthiazole Compounds with Antibacterial Potency by Modifying the Lipophilic Side Chain. ACS infectious diseases 6 (1) (2019)
Satish R Malwal, Lu Chen, Hunter Hicks, Fiona Qu, Weidong Liu, Alli Shillo, Wen Xuan Law, Jianan Zhang, Neal Chandnani, Xu Han, Yingying Zheng, Chun-Chi Chen, Rey-Ting Guo, Ahmed AbdelKhalek, Mohamed N Seleem, Eric Oldfield
Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis. Journal of medicinal chemistry 62 (5) (2019)
Ana V Morales-de-Echegaray, Thora R Maltais, Lu Lin, Waleed Younis, Naveen R Kadasala, Mohamed N Seleem, Alexander Wei
Rapid Uptake and Photodynamic Inactivation of Staphylococci by Ga(III)-Protoporphyrin IX. ACS infectious diseases 4 (11) (2018)
Mohamed Hagras, Nader S Abutaleb, Alsagher O Ali, Jelan A Abdel-Aleem, Mohamed M Elsebaei, Mohamed N Seleem, Abdelrahman S Mayhoub
Naphthylthiazoles: Targeting Multidrug-Resistant and Intracellular Staphylococcus aureus with Biofilm Disruption Activity. ACS infectious diseases 4 (12) (2018)
Manish Nepal, Mohamed F Mohamed, Reena Blade, Hassan E Eldesouky, Tiffany N Anderson, Mohamed N Seleem, Jean Chmielewski
A Library Approach to Cationic Amphiphilic Polyproline Helices that Target Intracellular Pathogenic Bacteria. ACS infectious diseases 4 (9) (2018)
Haroon Mohammad, Nehal H Elghazawy, Hassan E Eldesouky, Youssef A Hegazy, Waleed Younis, Larisa Avrimova, Tony Hazbun, Reem K Arafa, Mohamed N Seleem
Discovery of a Novel Dibromoquinoline Compound Exhibiting Potent Antifungal and Antivirulence Activity That Targets Metal Ion Homeostasis. ACS infectious diseases 4 (3) (2018)
Weili Hong, Caroline W Karanja, Nader S Abutaleb, Waleed Younis, Xueyong Zhang, Mohamed N Seleem, Ji-Xin Cheng
Antibiotic Susceptibility Determination within One Cell Cycle at Single-Bacterium Level by Stimulated Raman Metabolic Imaging. Analytical chemistry 90 (6) (2018)
Anna Brezden, Mohamed F Mohamed, Manish Nepal, John S Harwood, Jerrin Kuriakose, Mohamed N Seleem, Jean Chmielewski
Correction to "Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide". Journal of the American Chemical Society 140 (40) (2018)
Ahmed AbdelKhalek, Nader S Abutaleb, Haroon Mohammad, Mohamed N Seleem
Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE). PloS one 13 (6) (2018)
Ahmed AbdelKhalek, Nader S Abutaleb, Khalifa A Elmagarmid, Mohamed N Seleem
Repurposing auranofin as an intestinal decolonizing agent for vancomycin-resistant enterococci. Scientific reports 8 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Mohamed N Seleem