Hiroaki Wakimoto

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Science translational medicine

Journal for immunotherapy of cancer

Cells

Massachusetts General Hospital

Tokyo Medical and Dental University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital Nov 01 2019

United States

Associate professor :: Neurosurgery

Education History

Tokyo Medical and Dental University

Japan

PHD

Publications

Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Ami Kobayashi, Yosuke Kitagawa, Ali Nasser, Hiroaki Wakimoto, Keisuke Yamada, Shota Tanaka
Emerging Roles and Mechanisms of RNA Modifications in Neurodegenerative Diseases and Glioma. Cells 13 (5) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Ami Kobayashi, Yosuke Kitagawa, Ali Nasser, Hiroaki Wakimoto, Keisuke Yamada, Shota Tanaka
Emerging Roles and Mechanisms of RNA Modifications in Neurodegenerative Diseases and Glioma. Cells 13 (5) (2024)
Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Ami Kobayashi, Yosuke Kitagawa, Ali Nasser, Hiroaki Wakimoto, Keisuke Yamada, Shota Tanaka
Emerging Roles and Mechanisms of RNA Modifications in Neurodegenerative Diseases and Glioma. Cells 13 (5) (2024)
Ali M Nasser, Lisa Melamed, Ethan A Wetzel, Jenny Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller
CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Ali M Nasser, Lisa Melamed, Ethan A Wetzel, Jenny Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller
CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (14) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Praveen K Bommareddy, Hiroaki Wakimoto, Robert L Martuza, Howard L Kaufman, Samuel D Rabkin, Dipongkor Saha
Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival. Journal for immunotherapy of cancer 12 (4) (2024)
Ali M Nasser, Lisa Melamed, Ethan A Wetzel, Jenny Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller
CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (14) (2024)
Meng-Ju Wu, Hiroshi Kondo, Ashwin V Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab, Qin Xu, Chloe J Slater, Omar I Avila, Joshua Merritt, Hiroyuki Kato, Prabhat Kattel, Jonathan H Sussman, Ilaria Gritti, Jason Eccleston, Yi Sun, Hyo Min Cho, Kira E Olander, Takeshi Katsuda, Diana D Shi, Milan R Savani, Bailey C Smith, James M Cleary, Raul Mostoslavsky, Vindhya Vijay, Yosuke Kitagawa, Hiroaki Wakimoto, Russell William Jenkins, Kathleen B Yates, Jihye Paik, Ania Tassinari, Hatice Duygu Saatcioglu, Adriana E Tron, Wilhelm Haas, Daniel P Cahill, Samuel K McBrayer, Robert T Manguso, Nabeel El-Bardeesy
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science (New York, N.Y.) 385 (6705) (2024)
Ali M Nasser, Lisa Melamed, Ethan A Wetzel, Jenny Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller
CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (14) (2024)
Kok-Siong Chen, Clemens Reinshagen, Thijs A Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan G Simon, David A Reardon, Hiroaki Wakimoto, Khalid Shah
Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity. Science translational medicine 15 (677) (2023)
Kok-Siong Chen, Clemens Reinshagen, Thijs A Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan G Simon, David A Reardon, Hiroaki Wakimoto, Khalid Shah
Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity. Science translational medicine 15 (677) (2023)
Hirotaka Fudaba, Hiroaki Wakimoto
Oncolytic virus therapy for malignant gliomas: entering the new era. Expert opinion on biological therapy (2023)
Kok-Siong Chen, Clemens Reinshagen, Thijs A Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan G Simon, David A Reardon, Hiroaki Wakimoto, Khalid Shah
Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity. Science translational medicine 15 (677) (2023)
Nobuhiko Kanaya, Yohei Kitamura, Maria Lopez Vazquez, Arnaldo Franco, Kok-Siong Chen, Thijs A Van Schaik, Touraj Aligholipour Farzani, Paulo Borges, Toru Ichinose, Waleed Seddiq, Shinji Kuroda, Genevieve Marie Boland, Nusrat Jahan, David E Fisher, Hiroaki Wakimoto, Khalid Shah
Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas. Science translational medicine 15 (698) (2023)
Hirotaka Fudaba, Hiroaki Wakimoto
Oncolytic virus therapy for malignant gliomas: entering the new era. Expert opinion on biological therapy 23 (3) (2023)
Hirotaka Fudaba, Hiroaki Wakimoto
Oncolytic virus therapy for malignant gliomas: entering the new era. Expert opinion on biological therapy 23 (3) (2023)
Kok-Siong Chen, Clemens Reinshagen, Thijs A Van Schaik, Filippo Rossignoli, Paulo Borges, Natalia Claire Mendonca, Reza Abdi, Brennan G Simon, David A Reardon, Hiroaki Wakimoto, Khalid Shah
Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity. Science translational medicine 15 (677) (2023)
Jo Sasame, Naoki Ikegaya, Masahito Kawazu, Manabu Natsumeda, Takahiro Hayashi, Masataka Isoda, Kaishi Satomi, Arata Tomiyama, Akito Oshima, Hirokuni Honma, Yohei Miyake, Katsuhiro Takabayashi, Taishi Nakamura, Toshihide Ueno, Yuko Matsushita, Hiromichi Iwashita, Yu Kanemaru, Hidetoshi Murata, Akihide Ryo, Keita Terashima, Shoji Yamanaka, Yukihiko Fujii, Hiroyuki Mano, Takashi Komori, Koichi Ichimura, Daniel P Cahill, Hiroaki Wakimoto, Tetsuya Yamamoto, Kensuke Tateishi
HSP90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (11) (2022)
Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David L Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai-Lechtich, Clemens Reinshagen, Victoria Leon, Nabil Nissar, Wenya Linda Bi, Cheng Feng, Hongbin Li, Yu Shrike Zhang, Steven H Liang, Neil Vasdev, Walid Ibn Essayed, Pablo Valdes Quevedo, Alexandra Golby, Naima Banouni, Anna Palagina, Reza Abdi, Brian Fury, Stelios Manolis Smirnakis, Alarice Lowe, Brock Reeve, Arthur Hiller, E Antonio Chiocca, Glenn Prestwich, Hiroaki Wakimoto, Gerhard Bauer, Khalid Shah
Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells. Nature communications 13 (1) (2022)
Kazuhide Shimizu, Kaoru Tamura, Shoko Hara, Motoki Inaji, Yoji Tanaka, Daisuke Kobayashi, Takashi Sugawara, Hiroaki Wakimoto, Tadashi Nariai, Kenji Ishii, Ichiro Sakuma, Taketoshi Maehara
Correlation of Intraoperative 5-ALA-Induced Fluorescence Intensity and Preoperative 11 C-Methionine PET Uptake in Glioma Surgery. Cancers 14 (6) (2022)
Joshua K Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, Matthew R Strickland, Rebecca S Heist, Mohini Singh, Naema Nayyar, Anita Giobbie-Hurder, Subba R Digumarthy, Justin F Gainor, Anant P Rajan, Edwin Nieblas-Bedolla, Aaron C Burns, Jill Hallin, Peter Olson, James G Christensen, Sylvia C Kurz, Priscilla Kaliopi Brastianos, Hiroaki Wakimoto
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (15) (2022)
Norah Aldrak, Sarah Alsaab, Aliyah Algethami, Deepak Bhere, Hiroaki Wakimoto, Khalid Shah, Mohammad N Alomary, Nada M Zaidan
Oncolytic Herpes Simplex Virus-Based Therapies for Cancer. Cells 10 (6) (2021)
Kensuke Tateishi, Yohei Miyake, Masahito Kawazu, Nobuyoshi Sasaki, Taishi Nakamura, Jo Sasame, Yukie Yoshii, Toshihide Ueno, Jun Watanabe, Yuko Matsushita, Norio Shiba, Naoko Udaka, Kentaro Ohki, Alexandria L Fink, Shilpa S Tummala, Manabu Natsumeda, Naoki Ikegaya, Mayuko Nishi, Makoto Ohtake, Ryohei Miyazaki, Jun Suenaga, Hidetoshi Murata, Ichio Aoki, Julie J Miller, Yukihiko Fujii, Akihide Ryo, Shoji Yamanaka, Hiroyuki Mano, Daniel P Cahill, Hiroaki Wakimoto, Andrew S Chi, Tracy T Batchelor, Motoo Nagane, Koichi Ichimura, Tetsuya Yamamoto
A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma. Cancer research 80 (23) (2020)
Ming Li, Guoping Li, Juri Kiyokawa, Zain Tirmizi, Leland G Richardson, Jianfang Ning, Saumya Das, Robert L Martuza, Anat Stemmer-Rachamimov, Samuel D Rabkin, Hiroaki Wakimoto
Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma. Acta neuropathologica communications 8 (1) (2020)
Juri Kiyokawa, Yoichiro Kawamura, Shanawaz M Ghouse, Simge Acar, Erinç Barçın, Jordi Martínez-Quintanilla, Robert L Martuza, Ramon Alemany, Samuel D Rabkin, Khalid Shah, Hiroaki Wakimoto
Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (3) (2020)
Ming Li, Ameya R Kirtane, Juri Kiyokawa, Hiroaki Nagashima, Aaron Lopes, Zain A Tirmizi, Christine K Lee, Giovanni Traverso, Daniel P Cahill, Hiroaki Wakimoto
Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma. Cancer research 80 (22) (2020)
Fares Nigim, Juri Kiyokawa, Alessandra Gurtner, Yoichiro Kawamura, Lingyang Hua, Ekkehard M Kasper, Priscilla K Brastianos, Daniel P Cahill, Samuel D Rabkin, Robert L Martuza, W Shawn Carbonell, Hiroaki Wakimoto
A Monoclonal Antibody Against β1 Integrin Inhibits Proliferation and Increases Survival in an Orthotopic Model of High-Grade Meningioma. Targeted oncology 14 (4) (2020)
Hiroaki Nagashima, Christine K Lee, Kensuke Tateishi, Fumi Higuchi, Megha Subramanian, Seamus Rafferty, Lisa Melamed, Julie J Miller, Hiroaki Wakimoto, Daniel P Cahill
Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells. Cancer discovery 10 (11) (2020)
Satoshi Kofuji, Akiyoshi Hirayama, Alexander Otto Eberhardt, Risa Karakida Kawaguchi, Yuki Sugiura, Oltea Sampetrean, Yoshiki Ikeda, Mikako Warren, Naoya Sakamoto, Shuji Kitahara, Hirofumi Yoshino, Daisuke Yamashita, Kazutaka Sumita, Kara Wolfe, Lisa Lange, Satsuki Ikeda, Hiroko Shimada, Noriaki Minami, Akshiv Malhotra, Shin Morioka, Yuki Ban, Maya Asano, Victoria L Flanary, Annmarie Ramkissoon, Lionel M L Chow, Juri Kiyokawa, Tomoyuki Mashimo, Greg Lucey, Sergey Mareninov, Tatsuya Ozawa, Nobuyuki Onishi, Koichi Okumura, Jumpei Terakawa, Takiko Daikoku, Trisha Wise-Draper, Nazanin Majd, Kaori Kofuji, Mika Sasaki, Masaru Mori, Yonehiro Kanemura, Eric P Smith, Dimitrios Anastasiou, Hiroaki Wakimoto, Eric C Holland, William H Yong, Craig Horbinski, Ichiro Nakano, Ralph J DeBerardinis, Robert M Bachoo, Paul S Mischel, Wataru Yasui, Makoto Suematsu, Hideyuki Saya, Tomoyoshi Soga, Ingrid Grummt, Holger Bierhoff, Atsuo T Sasaki
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. Nature cell biology 21 (8) (2019)
Bryan D Choi, Xiaoling Yu, Ana P Castano, Amanda A Bouffard, Andrea Schmidts, Rebecca C Larson, Stefanie R Bailey, Angela C Boroughs, Matthew J Frigault, Mark B Leick, Irene Scarfo, Curtis L Cetrulo, Shadmehr Demehri, Brian V Nahed, Daniel P Cahill, Hiroaki Wakimoto, William T Curry, Bob S Carter, Marcela V Maus
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity. Nature biotechnology 37 (9) (2019)
Clemens Reinshagen, Deepak Bhere, Sung Hugh Choi, Stefan Hutten, Irina Nesterenko, Hiroaki Wakimoto, Eloi Le Roux, Alia Rizvi, Wanlu Du, Charles Minicucci, Khalid Shah
CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors. Science translational medicine 10 (449) (2019)
Fidan Seker, Ahmet Cingoz, İlknur Sur-Erdem, Nazli Erguder, Mahmut Alp Erkent, Fırat Uyulur, Myvizhi Esai Selvan, Zeynep Hülya Gümüş, Mehmet Gönen, Halil Bayraktar, Hiroaki Wakimoto, Tugba Bagci-Onder
Identification of SERPINE1 as a Regulator of Glioblastoma Cell Dispersal with Transcriptome Profiling. Cancers 11 (11) (2019)
Jian-Fang Ning, Monica Stanciu, Melissa R Humphrey, Joshua Gorham, Hiroko Wakimoto, Reiko Nishihara, Jacqueline Lees, Lee Zou, Robert L Martuza, Hiroaki Wakimoto, Samuel D Rabkin
Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma. Nature communications 10 (1) (2019)
Juri Kiyokawa, Hiroaki Wakimoto
Preclinical And Clinical Development Of Oncolytic Adenovirus For The Treatment Of Malignant Glioma. Oncolytic virotherapy 8 (2019)
Hiroshi Ito, Kosuke Watari, Tomohiro Shibata, Tomofumi Miyamoto, Yuichi Murakami, Yukiko Nakahara, Hiroto Izumi, Hiroaki Wakimoto, Michihiko Kuwano, Tatsuya Abe, Mayumi Ono
Bidirectional Regulation between NDRG1 and GSK3β Controls Tumor Growth and Is Targeted by Differentiation Inducing Factor-1 in Glioblastoma. Cancer research 80 (2) (2019)
Fares Nigim, Hiroaki Wakimoto, Ekkehard M Kasper, Linda Ackermans, Yasin Temel
Emerging Medical Treatments for Meningioma in the Molecular Era. Biomedicines 6 (3) (2018)
Shinichi Esaki, Fares Nigim, Esther Moon, Samantha Luk, Juri Kiyokawa, William Curry, Daniel P Cahill, Andrew S Chi, A John Iafrate, Robert L Martuza, Samuel D Rabkin, Hiroaki Wakimoto
Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models. International journal of cancer 141 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hiroaki Wakimoto