Ari M Melnick (Ari Melnick, Meng Li, A Melnick)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 92

Top Venues

Nature

Nature communications

Blood

Cancer discovery

Weill Cornell Medical College

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Weill Cornell Medical College

United States

Professor :: Medicine, Pharmacology, Immunology

Publications

Eliah G Overbey, Jang-Keun Kim, Braden T Tierney, Jiwoon Park, Nadia Houerbi, Alexander G Lucaci, Sebastian Garcia Medina, Namita Damle, Deena Najjar, Kirill Grigorev, Evan E Afshin, Krista A Ryon, Karolina Sienkiewicz, Laura Patras, Remi Klotz, Veronica Ortiz, Matthew MacKay, Annalise Schweickart, Christopher R Chin, Maria A Sierra, Matias F Valenzuela, Ezequiel Dantas, Theodore M Nelson, Egle Cekanaviciute, Gabriel Deards, Jonathan Foox, S Anand Narayanan, Caleb M Schmidt, Michael A Schmidt, Julian C Schmidt, Sean Mullane, Seth Stravers Tigchelaar, Steven Levitte, Craig Westover, Chandrima Bhattacharya, Serena Lucotti, Jeremy Wain Hirschberg, Jacqueline Proszynski, Marissa Burke, Ashley S Kleinman, Daniel J Butler, Conor Loy, Omary Mzava, Joan Lenz, Doru Paul, Christopher Mozsary, Lauren M Sanders, Lynn E Taylor, Chintan O Patel, Sharib A Khan, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Aaron S Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan W Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew M Boddicker, Junhua Zhao, Bryan Lajoie, Ryan T Scott, Rachel R Gilbert, San-Huei Lai Polo, Andrew Altomare, Semyon Kruglyak, Shawn Levy, Ishara Ariyapala, Joanne C Beer, Bingqing Zhang, Briana M Hudson, Aric Rininger, Sarah E Church, Afshin Behesti, George M Church, Scott M Smith, Brian E Crucian, Sara R Zwart, Irina R Matei, David C Lyden, Francine Garrett-Bakelman, Jan Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen Williams, Corey M Nemec, Guy Trudel, Martin Pelchat, Odette Laneuville, Iwijn De Vlaminck, Steven Gross, Kelly L Bolton, Susan M Bailey, Richard Granstein, David Furman, Ari M Melnick, Sylvain V Costes, Bader Hamza Shirah, Min Yu, Anil S Menon, Jaime Mateus, Cem Meydan, Christopher E Mason
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature 632 (8027) (2024)
Eliah G Overbey, Jang-Keun Kim, Braden T Tierney, Jiwoon Park, Nadia Houerbi, Alexander G Lucaci, Sebastian Garcia Medina, Namita Damle, Deena Najjar, Kirill Grigorev, Evan E Afshin, Krista A Ryon, Karolina Sienkiewicz, Laura Patras, Remi Klotz, Veronica Ortiz, Matthew MacKay, Annalise Schweickart, Christopher R Chin, Maria A Sierra, Matias F Valenzuela, Ezequiel Dantas, Theodore M Nelson, Egle Cekanaviciute, Gabriel Deards, Jonathan Foox, S Anand Narayanan, Caleb M Schmidt, Michael A Schmidt, Julian C Schmidt, Sean Mullane, Seth Stravers Tigchelaar, Steven Levitte, Craig Westover, Chandrima Bhattacharya, Serena Lucotti, Jeremy Wain Hirschberg, Jacqueline Proszynski, Marissa Burke, Ashley S Kleinman, Daniel J Butler, Conor Loy, Omary Mzava, Joan Lenz, Doru Paul, Christopher Mozsary, Lauren M Sanders, Lynn E Taylor, Chintan O Patel, Sharib A Khan, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Aaron S Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan W Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew M Boddicker, Junhua Zhao, Bryan Lajoie, Ryan T Scott, Rachel R Gilbert, San-Huei Lai Polo, Andrew Altomare, Semyon Kruglyak, Shawn Levy, Ishara Ariyapala, Joanne C Beer, Bingqing Zhang, Briana M Hudson, Aric Rininger, Sarah E Church, Afshin Behesti, George M Church, Scott M Smith, Brian E Crucian, Sara R Zwart, Irina R Matei, David C Lyden, Francine Garrett-Bakelman, Jan Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen Williams, Corey M Nemec, Guy Trudel, Martin Pelchat, Odette Laneuville, Iwijn De Vlaminck, Steven Gross, Kelly L Bolton, Susan M Bailey, Richard Granstein, David Furman, Ari M Melnick, Sylvain V Costes, Bader Hamza Shirah, Min Yu, Anil S Menon, Jaime Mateus, Cem Meydan, Christopher E Mason
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature (2024)
Eliah G Overbey, Jang-Keun Kim, Braden T Tierney, Jiwoon Park, Nadia Houerbi, Alexander G Lucaci, Sebastian Garcia Medina, Namita Damle, Deena Najjar, Kirill Grigorev, Evan E Afshin, Krista A Ryon, Karolina Sienkiewicz, Laura Patras, Remi Klotz, Veronica Ortiz, Matthew MacKay, Annalise Schweickart, Christopher R Chin, Maria A Sierra, Matias F Valenzuela, Ezequiel Dantas, Theodore M Nelson, Egle Cekanaviciute, Gabriel Deards, Jonathan Foox, S Anand Narayanan, Caleb M Schmidt, Michael A Schmidt, Julian C Schmidt, Sean Mullane, Seth Stravers Tigchelaar, Steven Levitte, Craig Westover, Chandrima Bhattacharya, Serena Lucotti, Jeremy Wain Hirschberg, Jacqueline Proszynski, Marissa Burke, Ashley S Kleinman, Daniel J Butler, Conor Loy, Omary Mzava, Joan Lenz, Doru Paul, Christopher Mozsary, Lauren M Sanders, Lynn E Taylor, Chintan O Patel, Sharib A Khan, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Aaron S Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan W Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew M Boddicker, Junhua Zhao, Bryan Lajoie, Ryan T Scott, Rachel R Gilbert, San-Huei Lai Polo, Andrew Altomare, Semyon Kruglyak, Shawn Levy, Ishara Ariyapala, Joanne C Beer, Bingqing Zhang, Briana M Hudson, Aric Rininger, Sarah E Church, Afshin Behesti, George M Church, Scott M Smith, Brian E Crucian, Sara R Zwart, Irina R Matei, David C Lyden, Francine Garrett-Bakelman, Jan Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen Williams, Corey M Nemec, Guy Trudel, Martin Pelchat, Odette Laneuville, Iwijn De Vlaminck, Steven Gross, Kelly L Bolton, Susan M Bailey, Richard Granstein, David Furman, Ari M Melnick, Sylvain V Costes, Bader Hamza Shirah, Min Yu, Anil S Menon, Jaime Mateus, Cem Meydan, Christopher E Mason
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature (2024)
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martín A Rivas, Oliver Weigert, Trevor J Pugh, Amy Chadburn, Christian Steidl, David W Scott, Robert G Roeder, Christopher E Mason, Roberta Zappasodi, Wendy Béguelin, Ari M Melnick
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nature communications 15 (1) (2024)
Sadhan Jana, Jialin Shang, Jun Young Hong, Michael K Fenwick, Rishi Puri, Xuan Lu, Ari M Melnick, Meng Li, Hening Lin
A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. Journal of medicinal chemistry (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature 632 (8027) (2024)
Kirill Grigorev, Theodore M Nelson, Eliah G Overbey, Nadia Houerbi, Jang-Keun Kim, Deena Najjar, Namita Damle, Evan E Afshin, Krista A Ryon, Jean Thierry-Mieg, Danielle Thierry-Mieg, Ari M Melnick, Jaime Mateus, Christopher E Mason
Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses. Nature communications 15 (1) (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature 632 (8027) (2024)
Kirill Grigorev, Theodore M Nelson, Eliah G Overbey, Nadia Houerbi, Jang-Keun Kim, Deena Najjar, Namita Damle, Evan E Afshin, Krista A Ryon, Jean Thierry-Mieg, Danielle Thierry-Mieg, Ari M Melnick, Jaime Mateus, Christopher E Mason
Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses. Nature communications 15 (1) (2024)
Eliah G Overbey, Jang-Keun Kim, Braden T Tierney, Jiwoon Park, Nadia Houerbi, Alexander G Lucaci, Sebastian Garcia Medina, Namita Damle, Deena Najjar, Kirill Grigorev, Evan E Afshin, Krista A Ryon, Karolina Sienkiewicz, Laura Patras, Remi Klotz, Veronica Ortiz, Matthew MacKay, Annalise Schweickart, Christopher R Chin, Maria A Sierra, Matias F Valenzuela, Ezequiel Dantas, Theodore M Nelson, Egle Cekanaviciute, Gabriel Deards, Jonathan Foox, S Anand Narayanan, Caleb M Schmidt, Michael A Schmidt, Julian C Schmidt, Sean Mullane, Seth Stravers Tigchelaar, Steven Levitte, Craig Westover, Chandrima Bhattacharya, Serena Lucotti, Jeremy Wain Hirschberg, Jacqueline Proszynski, Marissa Burke, Ashley S Kleinman, Daniel J Butler, Conor Loy, Omary Mzava, Joan Lenz, Doru Paul, Christopher Mozsary, Lauren M Sanders, Lynn E Taylor, Chintan O Patel, Sharib A Khan, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Aaron S Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan W Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew M Boddicker, Junhua Zhao, Bryan Lajoie, Ryan T Scott, Rachel R Gilbert, San-Huei Lai Polo, Andrew Altomare, Semyon Kruglyak, Shawn Levy, Ishara Ariyapala, Joanne C Beer, Bingqing Zhang, Briana M Hudson, Aric Rininger, Sarah E Church, Afshin Behesti, George M Church, Scott M Smith, Brian E Crucian, Sara R Zwart, Irina R Matei, David C Lyden, Francine Garrett-Bakelman, Jan Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen Williams, Corey M Nemec, Guy Trudel, Martin Pelchat, Odette Laneuville, Iwijn De Vlaminck, Steven Gross, Kelly L Bolton, Susan M Bailey, Richard Granstein, David Furman, Ari M Melnick, Sylvain V Costes, Bader Hamza Shirah, Min Yu, Anil S Menon, Jaime Mateus, Cem Meydan, Christopher E Mason
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature (2024)
Christopher E Mason, James Green, Konstantinos I Adamopoulos, Evan E Afshin, Jordan J Baechle, Mathias Basner, Susan M Bailey, Luca Bielski, Josef Borg, Joseph Borg, Jared T Broddrick, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Subhamoy Chatterjee, Christopher R Chin, George M Church, Sylvain V Costes, Iwijn De Vlaminck, Rajeev I Desai, Raja Dhir, Juan Esteban Diaz, Sofia M Etlin, Zachary Feinstein, David Furman, J Sebastian Garcia-Medina, Francine Garrett-Bakelman, Stefania Giacomello, Anjali Gupta, Amira Hassanin, Nadia Houerbi, Iris Irby, Emilia Javorsky, Peter Jirak, Christopher W Jones, Khaled Y Kamal, Brian D Kangas, Fathi Karouia, Jang-Keun Kim, Joo Hyun Kim, Ashley S Kleinman, Try Lam, John M Lawler, Jessica Audrey Lee, Charles L Limoli, Alexander Lucaci, Matthew MacKay, J Tyson McDonald, Ari M Melnick, Cem Meydan, Jakub Mieczkowski, Masafumi Muratani, Deena Najjar, Mariam Atef Othman, Eliah G Overbey, Vera Paar, Jiwoon Park, Amber M Paul, Adrian Perdyan, Jacqueline Proszynski, Robert J Reynolds, April E Ronca, Kate Rubins, Krista A Ryon, Lauren M Sanders, Patricia Savi Glowe, Yash Shevde, Michael A Schmidt, Ryan T Scott, Bader Hamza Shirah, Karolina Sienkiewicz, Maria A Sierra, Keith Siew, Corey A Theriot, Braden T Tierney, Kasthuri Venkateswaran, Jeremy Wain Hirschberg, Stephen B Walsh, Claire Walter, Daniel A Winer, Min Yu, Luis Zea, Jaime Mateus, Afshin Behesti
A second space age spanning omics, platforms and medicine across orbits. Nature 632 (8027) (2024)
Kirill Grigorev, Theodore M Nelson, Eliah G Overbey, Nadia Houerbi, Jang-Keun Kim, Deena Najjar, Namita Damle, Evan E Afshin, Krista A Ryon, Jean Thierry-Mieg, Danielle Thierry-Mieg, Ari M Melnick, Jaime Mateus, Christopher E Mason
Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses. Nature communications 15 (1) (2024)
Christopher W Jones, Eliah G Overbey, J Lacombe, A J Ecker, Cem Meydan, K Ryon, Braden T Tierney, N Damle, M MacKay, E E Afshin, J Foox, Jiwoon Park, Theodore M Nelson, M Suhail, S G Byhaqui, B Aslam, U A Tali, L Nisa, P Menon, C O Patel, S A Khan, D J Ebert, A Everson, M C Schubert, N N Ali, Mallika S Sarma, Jang-Keun Kim, N Houerbi, Kirill Grigorev, S Garcia Medina, Alexander J Summers, J Gu, J A Altin, Ali Fattahi, Mohammad I Hirzallah, J H Wu, Alexander C Stahn, Afshin Behesti, R Klotz, V Ortiz, M Yu, L Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, S Mullane, A Kleinman, M Loesche, Anil S Menon, D B Donoviel, E Urquieta, J Mateus, A E Sargsyan, M Shelhamer, F Zenhausern, E M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew. Nature (2024)
Jang-Keun Kim, Braden T Tierney, Eliah G Overbey, Ezequiel Dantas, Matias Fuentealba, Jiwoon Park, S Anand Narayanan, Fei Wu, Deena Najjar, Christopher R Chin, Cem Meydan, Conor Loy, Aydogan Mathyk Begum, Remi Klotz, Veronica Ortiz, Khiem Nguyen, Krista A Ryon, Namita Damle, Nadia Houerbi, Laura I Patras, Nathan Schanzer, Gwyneth A Hutchinson, Jonathan Foox, Chandrima Bhattacharya, Matthew Mackay, Evan E Afshin, Jeremy Wain Hirschberg, Ashley S Kleinman, Julian C Schmidt, Caleb M Schmidt, Michael A Schmidt, Afshin Behesti, Irina R Matei, David C Lyden, Sean Mullane, Amran Asadi, Joan S Lenz, Omary Mzava, Min Yu, Saravanan Ganesan, Iwijn De Vlaminck, Ari M Melnick, Darko Barisic, Daniel A Winer, Sara R Zwart, Brian E Crucian, Scott M Smith, Jaime Mateus, David Furman, Christopher E Mason
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight. Nature communications 15 (1) (2024)
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martín A Rivas, Oliver Weigert, Trevor J Pugh, Amy Chadburn, Christian Steidl, David W Scott, Robert G Roeder, Christopher E Mason, Roberta Zappasodi, Wendy Béguelin, Ari M Melnick
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nature communications 15 (1) (2024)
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martín A Rivas, Oliver Weigert, Trevor J Pugh, Amy Chadburn, Christian Steidl, David W Scott, Robert G Roeder, Christopher E Mason, Roberta Zappasodi, Wendy Béguelin, Ari M Melnick
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nature communications 15 (1) (2024)
Christopher E Mason, James Green, Konstantinos I Adamopoulos, Evan E Afshin, Jordan J Baechle, Mathias Basner, Susan M Bailey, Luca Bielski, Josef Borg, Joseph Borg, Jared T Broddrick, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Subhamoy Chatterjee, Christopher R Chin, George M Church, Sylvain V Costes, Iwijn De Vlaminck, Rajeev I Desai, Raja Dhir, Juan Esteban Diaz, Sofia M Etlin, Zachary Feinstein, David Furman, J Sebastian Garcia-Medina, Francine Garrett-Bakelman, Stefania Giacomello, Anjali Gupta, Amira Hassanin, Nadia Houerbi, Iris Irby, Emilia Javorsky, Peter Jirak, Christopher W Jones, Khaled Y Kamal, Brian D Kangas, Fathi Karouia, Jang-Keun Kim, Joo Hyun Kim, Ashley S Kleinman, Try Lam, John M Lawler, Jessica Audrey Lee, Charles L Limoli, Alexander Lucaci, Matthew MacKay, J Tyson McDonald, Ari M Melnick, Cem Meydan, Jakub Mieczkowski, Masafumi Muratani, Deena Najjar, Mariam Atef Othman, Eliah G Overbey, Vera Paar, Jiwoon Park, Amber M Paul, Adrian Perdyan, Jacqueline Proszynski, Robert J Reynolds, April E Ronca, Kate Rubins, Krista A Ryon, Lauren M Sanders, Patricia Savi Glowe, Yash Shevde, Michael A Schmidt, Ryan T Scott, Bader Hamza Shirah, Karolina Sienkiewicz, Maria A Sierra, Keith Siew, Corey A Theriot, Braden T Tierney, Kasthuri Venkateswaran, Jeremy Wain Hirschberg, Stephen B Walsh, Claire Walter, Daniel A Winer, Min Yu, Luis Zea, Jaime Mateus, Afshin Behesti
A second space age spanning omics, platforms and medicine across orbits. Nature (2024)
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martín A Rivas, Oliver Weigert, Trevor J Pugh, Amy Chadburn, Christian Steidl, David W Scott, Robert G Roeder, Christopher E Mason, Roberta Zappasodi, Wendy Béguelin, Ari M Melnick
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nature communications 15 (1) (2024)
Ana Portelinha, Shenqiu Wang, Sara Parsa, Man Jiang, Alexander N Gorelick, Sagarajit Mohanty, Soumya Sharma, Elisa De Stanchina, Marjan Berishaj, Chunying Zhao, James Heward, Neeraj K Aryal, Omid Tavana, Jiayu Wen, Jude Fitzgibbon, Ahmet Dogan, Anas Younes, Ari M Melnick, Hans-Guido Wendel
SETD1B mutations confer apoptosis resistance and BCL2 independence in B cell lymphoma. The Journal of experimental medicine 221 (10) (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature 632 (8027) (2024)
Jang-Keun Kim, Braden T Tierney, Eliah G Overbey, Ezequiel Dantas, Matias Fuentealba, Jiwoon Park, S Anand Narayanan, Fei Wu, Deena Najjar, Christopher R Chin, Cem Meydan, Conor Loy, Aydogan Mathyk Begum, Remi Klotz, Veronica Ortiz, Khiem Nguyen, Krista A Ryon, Namita Damle, Nadia Houerbi, Laura I Patras, Nathan Schanzer, Gwyneth A Hutchinson, Jonathan Foox, Chandrima Bhattacharya, Matthew Mackay, Evan E Afshin, Jeremy Wain Hirschberg, Ashley S Kleinman, Julian C Schmidt, Caleb M Schmidt, Michael A Schmidt, Afshin Behesti, Irina R Matei, David C Lyden, Sean Mullane, Amran Asadi, Joan S Lenz, Omary Mzava, Min Yu, Saravanan Ganesan, Iwijn De Vlaminck, Ari M Melnick, Darko Barisic, Daniel A Winer, Sara R Zwart, Brian E Crucian, Scott M Smith, Jaime Mateus, David Furman, Christopher E Mason
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight. Nature communications 15 (1) (2024)
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martín A Rivas, Oliver Weigert, Trevor J Pugh, Amy Chadburn, Christian Steidl, David W Scott, Robert G Roeder, Christopher E Mason, Roberta Zappasodi, Wendy Béguelin, Ari M Melnick
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nature communications 15 (1) (2024)
Christopher W Jones, Eliah G Overbey, Jerome Lacombe, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden T Tierney, Namita Damle, Matthew MacKay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jang-Keun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Behesti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina R Matei, David C Lyden, Ari M Melnick, Neil T Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Nature 632 (8027) (2024)
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Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan, Daniel T Gildea, Samuel Haddox, Tak Lee, H Moses Murdock, Caroline Sheridan, Alexis Thurmond, Ling Wang, Martin Carroll, Larry D Cripe, Hugo Fernandez, Christopher E Mason, Elisabeth Paietta, Gail J Roboz, Zhuoxin Sun, Martin S Tallman, Yanming Zhang, Mithat Gönen, Ross L Levine, Ari M Melnick, Maria Kleppe, Francine E Garrett-Bakelman
Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999. Blood cancer journal 12 (9) (2022)
Luca Vincenzo Cappelli, Danilo Fiore, Jude M Phillip, Liron Yoffe, Filomena Di Giacomo, William Chiu, Yang Hu, Clarisse Kayembe, Michael Ginsberg, Lorena Consolino, José Gabriel Barcia Durán, Nahuel Zamponi, Ari M Melnick, Francesco Boccalatte, Wayne Tam, Olivier Elemento, Sabina Chiaretti, Anna Rita Guarini, Robin Foà, Leandro Cerchietti, Shahin Rafii, Giorgio Ga Inghirami
Endothelial-leukemia interactions remodel drug responses uncovering T-ALL vulnerabilities. Blood (2022)
Ruth Flumann, Julia Hansen, Benedikt W Pelzer, Pascal Nieper, Tim Lohmann, Ilmars Kisis, Tobias Riet, Viktoria Kohlhas, Phuong-Hien Nguyen, Martin Peifer, Nima Abedpour, Graziella Bosco, Roman K Thomas, Moritz Kochanek, Jacqueline Knufer, Lorenz Jonigkeit, Filippo Beleggia, Alessandra M E Holzem, Reinhard Buttner, Philipp Lohneis, Jorn Meinel, Monika Ortmann, Thorsten Persigehl, Michael Hallek, Dinis Pedro Calado, Markus Chmielewski, Sebastian Klein, Joachim R Göthert, Bjoern Chapuy, Elena I Rugarli, Frank Thomas Wunderlich, Bastian von Tresckow, Ron D Jachimowicz, Ari M Melnick, Hans Christian Reinhardt, Gero Knittel
Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies. Blood cancer discovery (2022)
Laurence L de Leval, Ash A Alizadeh, Peter Leif Bergsagel, Elias Campo, Andrew John Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M Horwitz, Ari M Melnick, William George Morice, Ryan D Morin, Bertrand Nadel, Stefano A Pileri, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P Treon, Andrew D Zelenetz, Ranjana H Advani, Carl E Allen, Stephen M Ansell, Wing C John Chan, James R Cook, Lucy B M Cook, Francesco d'Amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew L Feldman, Falko Fend, Philippe Gaulard, Paolo Ghia, John G Gribben, Olivier Hermine, Daniel James Hodson, Eric D Hsi, Giorgio Ga Inghirami, Elaine S Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L King, Young-Hyeh Ko, Ann Steward LaCasce, Georg Lenz, José I Martin-Subero, Miguel Angel Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-Fend, Scott J Rodig, Andreas Rosenwald, Gilles Andre Salles, Jesús San F Miguel, Kerry Joane Savage, Laurie Helen Sehn, Gianpietro C Semenzato, Louis M Staudt, Steven Howard Swerdlow, Constantine S Tam, Judith Trotman, Julie M Vose, Oliver Weigert, Wyndham H Wilson, Jane N Winter, Catherine J Wu, Pier Luigi Luigi Zinzani, Emanuele Zucca, Adam Bagg, David W Scott
Genomic profiling for clinical decision making in lymphoid neoplasms. Blood 140 (21) (2022)
Ari M Melnick
Tee-ing up a New Follicular Lymphoma Classification System. Blood cancer discovery 3 (5) (2022)
Min Xia, Liron David, Matthew R Teater, Johana Gutierrez, Xiang Wang, Cem Meydan, Andrew Lytle, Graham W Slack, David W Scott, Ryan D Morin, Özlem Önder, Kojo S J Elenitoba-Johnson, Nahuel Zamponi, Leandro Cerchietti, Tianbao Lu, Ulrike Philippar, Lorena Fontán, Hao Wu, Ari M Melnick
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Cancer discovery 12 (8) (2022)
Tatiana Erazo, Chiara M Evans, Daniel Zakheim, Karen L Chu, Alice Yunsi Refermat, Zahra Asgari, Xuejing Yang, Mariana Da Silva Ferreira, Sanjoy Mehta, Marco Vincenzo Russo, Andrea Knezevic, Xi-Ping Zhang, Zhengming Chen, Myles Fennell, Ralph Garippa, Venkatraman E Seshan, Elisa de Stanchina, Olena Barbash, Connie Lee Batlevi, Christina S Leslie, Ari M Melnick, Anas Younes, Michael Gregory Kharas
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma. Nature communications 13 (1) (2022)
Laura Barreyro, Avery M Sampson, Chiharu Ishikawa, Kathleen M Hueneman, Kwangmin Choi, Mario A Pujato, Somchai Chutipongtanate, Michael Wyder, Wendy D Haffey, Eric O'Brien, Mark Wunderlich, Vighnesh Ramesh, Ellen K Gagliani, Cem Meydan, Yaseswini Neelamraju, Lyndsey C Bolanos, Susanne Christie, Molly A Smith, Madeline Niederkorn, Tomoya Muto, Santosh Kesari, Francine E Garrett-Bakelman, Boris Bartholdy, Britta Will, Matthew T Weirauch, James C Mulloy, Zartash Gul, Stephen Medlin, Rhett A Kovall, Ari M Melnick, John P Perentesis, Kenneth D Greis, Elmar Nurmemmedov, William L Seibel, Daniel T Starczynowski
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine 14 (635) (2022)
Aditya S Deshpande, Netha Ulahannan, Matthew Pendleton, Xiaoguang Dai, Lynn Ly, Julie M Behr, Stefan Schwenk, Will Liao, Michael A Augello, Carly Tyer, Priyesh Rughani, Sarah Kudman, Huasong Tian, Hannah G Otis, Emily Adney, David C Wilkes, Juan-Miguel Mosquera, Christopher E Barbieri, Ari M Melnick, David Stoddart, Daniel J Turner, Sissel Juul, Eoghan Harrington, Marcin Imielinski
Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing. Nature biotechnology 40 (10) (2022)
Ruth Flümann, Tim Rehkämper, Pascal Nieper, Pauline Pfeiffer, Alessandra Holzem, Sebastian Klein, Sanil Bhatia, Moritz Kochanek, Ilmars Kisis, Benedikt W Pelzer, Heinz Ahlert, Julia Hauer, Alexandra da Palma Guerreiro, Jeremy Adam Ryan, Maurice Reimann, Arina Riabinska, Janica Wiederstein, Marcus Krüger, Martina Deckert, Janine Altmüller, Andreas R Klatt, Lukas P Frenzel, Laura Pasqualucci, Wendy Béguelin, Ari M Melnick, Sandrine Sander, Manuel Montesinos-Rongen, Anna Brunn, Philipp Lohneis, Reinhard Büttner, Hamid Kashkar, Arndt Borkhardt, Anthony Letai, Thorsten Persigehl, Martin Peifer, Clemens A Schmitt, Hans Christian Reinhardt, Gero Knittel
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood cancer discovery 2 (1) (2022)
Elias Campo, Elaine S Jaffe, James R Cook, Leticia Quintanilla-Fend, Steven H Swerdlow, Kenneth C Anderson, Pierre Brousset, Lorenzo Cerroni, Laurence de Leval, Stefan Dirnhofer, Ahmet Dogan, Andrew L Feldman, Falko Fend, Jonathan W Friedberg, Philippe Gaulard, Paolo Ghia, Steven M Horwitz, Rebecca L King, Gilles Andre Salles, Jesús San F Miguel, John Francis Seymour, Steven P Treon, Julie M Vose, Emanuele Zucca, Ranjana Advani, Stephen Ansell, Wing-Yan Au, Carlos Barrionuevo, Peter Leif Bergsagel, Wing C Chan, Jeffrey I Cohen, Francesco d'Amore, Andrew John Davies, Brunangelo Falini, Irene M Ghobrial, Mariusz A Wasik, John G Gribben, Eric D Hsi, Brad S Kahl, Won-Seog Kim, Shaji K Kumar, Ann Steward LaCasce, Camille Laurent, Georg Lenz, John P Leonard, Michael P Link, Armando Lopez-Guillermo, Maria-Victoria Mateos-Manteca, Elizabeth A Macintyre, Ari M Melnick, Judith Trotman, Shigeo Nakamura, Marina Narbaitz, Astrid Pavlovsky, Stefano A Pileri, Miguel Angel Piris, Barbara Pro, Vincent Rajkumar, Steven T Rosen, Birgitta Sander, Laurie Sehn, Margaret A Shipp, Sonali M Smith, Louis M Staudt, Catherine Thieblemont, Thomas Tousseyn, Wyndham H Wilson, Tadashi Yoshino, Pier Luigi Luigi Zinzani, Martin Dreyling, David W Scott, Jane N Winter, Andrew D Zelenetz
The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee. Blood 140 (11) (2022)
Wilfred Leung, Matthew R Teater, Ceyda Durmaz, Cem Meydan, Alexandra G Chivu, Amy Chadburn, Edward J Rice, Ashlesha Muley, Jeannie M Camarillo, Jaison Arivalagan, Ziyi Li, Christopher R Flowers, Michael P Snyder, Charles G Danko, Marcin Imielinski, Sandeep S Dave, Scott A Armstrong, Christopher E Mason, Ari M Melnick
SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis. Cancer discovery 12 (7) (2022)
Leandro Venturutti, Martín A Rivas, Benedikt W Pelzer, Ruth Flumann, Julia Hansen, Ioannis Karagiannidis, Min Xia, Dylan R McNally, Yusuke Isshiki, Andrew Lytle, Matthew R Teater, Christopher R Chin, Cem Meydan, Gero Knittel, Edd Ricker, Christopher E Mason, Xiaofei Ye, Qiang Pan-Hammarström, Christian Steidl, David W Scott, Hans Christian Reinhardt, Alessandra B Pernis, Wendy Béguelin, Ari M Melnick
An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas. Cancer discovery (2022)
Kibaek Choe, Yusaku Hontani, Tianyu Wang, Eric Hebert, Dimitre G Ouzounov, Kristine Lai, Ankur Singh, Wendy Béguelin, Ari M Melnick, Chris Xu
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes. Nature immunology 23 (2) (2022)
Yong Ai, Lucia Hwang, Alexander D MacKerell, Ari M Melnick, Fengtian Xue
Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond. Journal of medicinal chemistry 64 (8) (2021)
Luis Vitores Valcárcel, Ane Amundarain, Marta Kulis, Stella Charalampopoulou, Ari M Melnick, Jesús San F Miguel, José Ignacio Martin-Subero, Francisco J Planes, Xabier Agirre, Felipe Prosper
Gene expression derived from alternative promoters improves prognostic stratification in multiple myeloma. Leukemia 35 (10) (2021)
Nikita Kotlov, Alexander V Bagaev, Maria Victoria Revuelta, Jude M Phillip, Maria Teresa Cacciapuoti, Zoya Antysheva, Viktor Svekolkin, Ekaterina Tikhonova, Natalia Miheecheva, Natalia Kuzkina, Grigorii Nos, Fabrizio Tabbò, Felix E Frenkel, Paola Ghione, Maria Tsiper, Nava Almog, Nathan Fowler, Ari M Melnick, John P Leonard, Giorgio Inghirami, Leandro Cerchietti
Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures. Cancer discovery 11 (6) (2021)
Cihangir Duy, Meng Li, Matthew R Teater, Cem Meydan, Francine E Garrett-Bakelman, Tak C Lee, Christopher R Chin, Ceyda Durmaz, Kimihito C Kawabata, Eugen Dhimolea, Constantine S Mitsiades, Hartmut Doehner, Richard J D'Andrea, Michael W Becker, Elisabeth M Paietta, Christopher E Mason, Martin Carroll, Ari M Melnick
Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence. Cancer discovery 11 (6) (2021)
Martín A Rivas, Cem Meydan, Christopher R Chin, Matt F Challman, Daleum Kim, Bhavneet Bhinder, Andreas Kloetgen, Aaron D Viny, Matt R Teater, Dylan R McNally, Ashley S Doane, Wendy Béguelin, María Teresa Calvo Fernández, Hao Shen, Xiang Wang, Ross L Levine, Zhengming Chen, Aristotelis Tsirigos, Olivier Elemento, Christopher E Mason, Ari M Melnick
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nature immunology 22 (2) (2021)
Elisabeth Paietta, Kathryn G Roberts, Victoria Wang, Zhaohui Gu, Georgina A N Buck, Deqing Pei, Cheng Cheng, Ross L Levine, Omar Abdel-Wahab, Zhongshan Cheng, Gang Wu, Chunxu Qu, Lei Shi, Stanley Pounds, Cheryl L Willman, Richard C Harvey, Janis Racevskis, Jan Barinka, Yanming Zhang, Gordon W Dewald, Rhett P Ketterling, David Alejos, Hillard M Lazarus, Selina M Luger, Letizia Foroni, Bela Patel, Adele K Fielding, Ari M Melnick, David I Marks, Anthony V Moorman, Peter H Wiernik, Jacob M Rowe, Martin S Tallman, Anthony H Goldstone, Charles G Mullighan, Mark R Litzow
Molecular classification improves risk assessment in adult BCR-ABL1-negative B-ALL. Blood 138 (11) (2021)
James Heward, Lola Konali, Annalisa D'Avola, Karina Close, Alison Yeomans, Martin Philpott, James E Dunford, Tahrima Rahim, Ahad F Al Seraihi, Jun Wang, Koorosh Korfi, Shamzah Araf, Sameena Iqbal, Findlay Bewicke-Copley, Emil Kumar, Darko Barisic, Maria Calaminici, Andrew James Clear, John G Gribben, Peter W M Johnson, Richard Neve, Pedro Rodriguez Cutillas, Jessica Okosun, Udo Oppermann, Ari M Melnick, Graham Packham, Jude Fitzgibbon
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas. Blood 138 (5) (2021)
Alexey A Soshnev, C David Allis, Ethel Cesarman, Ari M Melnick
Histone H1 mutations in lymphoma: a link(er) between chromatin organization, developmental reprogramming, and cancer. Cancer research (2021)
Franck Rapaport, Yaseswini Neelamraju, Timour Baslan, Duane Hassane, Agata Gruszczynska, Marc Robert de Massy, Noushin Farnoud, Samuel Haddox, Tak Lee, Juan Medina-Martinez, Caroline Sheridan, Alexis Thurmond, Michael Becker, Stefan Bekiranov, Martin Carroll, Heardly Moses Murdock, Peter J M Valk, Lars Bullinger, Richard D'Andrea, Scott W Lowe, Donna S Neuberg, Ross L Levine, Ari M Melnick, Francine E Garrett-Bakelman
Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia. Leukemia 35 (9) (2021)
Roger Mulet-Lazaro, Stanley van Herk, Claudia A J Erpelinck-Verschueren, Eric Bindels, Mathijs Arnoud Sanders, Carlo Vermeulen, Ivo Renkens, Peter Valk, Ari M Melnick, Jeroen de Ridder, Michael Rehli, Claudia Gebhard, Ruud Delwel, Bas J Wouters
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML. Blood 138 (2) (2021)
Meng Li, Matthew R Teater, Jun Young Hong, Noel R Park, Cihangir Duy, Hao Shen, Ling Wang, Zhengming Chen, Leandro Cerchietti, Shawn M Davidson, Hening Lin, Ari M Melnick
Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival. Blood cancer discovery 3 (1) (2021)
Ashley S Doane, Chi-Shuen Chu, Dafne Campigli Di Giammartino, Martín A Rivas, Johannes C Hellmuth, Yanwen Jiang, Nevin Yusufova, Alicia Alonso, Robert G Roeder, Effie Apostolou, Ari M Melnick, Olivier Elemento
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity. Nature immunology 22 (10) (2021)
Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew MacKay, Fritz J Sedlazeck, Nikolay A Ivanov, Maria Sierra, Diana Pohle, Michael Zietz, Undina Gisladottir, Vijendra Ramlall, Evan T Sholle, Edward J Schenck, Craig D Westover, Ciaran Hassan, Krista Ryon, Benjamin Young, Chandrima Bhattacharya, Dianna L Ng, Andrea C Granados, Yale A Santos, Venice Servellita, Scot Federman, Phyllis Ruggiero, Arkarachai Fungtammasan, Chen-Shan Chin, Nathaniel M Pearson, Bradley W Langhorst, Nathan A Tanner, Youngmi Kim, Jason W Reeves, Tyler D Hether, Sarah E Warren, Michael Bailey, Justyna Gawrys, Dmitry Meleshko, Dong Xu, Mara Couto-Rodriguez, Dorottya Nagy-Szakal, Joseph Barrows, Heather Wells, Niamh B O'Hara, Jeffrey A Rosenfeld, Ying Chen, Peter A D Steel, Amos J Shemesh, Jenny Xiang, Jean Thierry-Mieg, Danielle Thierry-Mieg, Angelika Iftner, Daniela Bezdan, Elizabeth Sanchez, Thomas R Campion, John Sipley, Lin Cong, Arryn Craney, Priya Velu, Ari M Melnick, Sagi D Shapira, Iman Hajirasouliha, Alain C Borczuk, Thomas Iftner, Mirella Salvatore, Massimo Loda, Lars F Westblade, Melissa Cushing, Shixiu Wu, Shawn E Levy, Charles Y Chiu, Robert E Schwartz, Nicholas P Tatonetti, Hanna Rennert, Marcin Imielinski, Christopher E Mason
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Nature communications 12 (1) (2021)
Arantxa Carrasco-Leon, Teresa Ezponda, Cem Meydan, Luis Vitores Valcárcel, Raquel Ordoñez, Marta Kulis, Leire Garate, Estíbaliz Miranda, Victor Segura, Elisabeth Guruceaga, Amaia Vilas-Zornoza, Diego Alignani, Marién Pascual, Ane Amundarain, Laura Castro-Labrador, Patxi San Martín-Uriz, Halima El-Omri, Ruba Y Taha, María-José Calasanz, Francisco J Planes, Juan José Lahuerta, Christopher E Mason, Jesús San F Miguel, José Ignacio Martin-Subero, Ari M Melnick, Felipe Prosper, Xabier Agirre
Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma. Leukemia 35 (5) (2021)
Meng Li, Ari M Melnick
Non-oncogene Addiction to SIRT5 in Acute Myeloid Leukemia. Blood cancer discovery 2 (3) (2021)
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian O Ellis, Andrew Green, Francine E Garrett-Bakelman, Christopher E Mason, Ari M Melnick, Samuel A J R Aparicio, Oscar M Rueda, Amos Tanay, Carlos Caldas
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation. Nature communications 12 (1) (2021)
Michael A Willcockson, Sean E Healton, Cary N Weiss, Boris A Bartholdy, Yair Botbol, Laxmi N Mishra, Dhruv S Sidhwani, Tommy J Wilson, Hugo B Pinto, Maxim I Maron, Karin A Skalina, Laura Norwood Toro, Jie Zhao, Chul-Hwan Lee, Harry Hou, Nevin Yusufova, Cem Meydan, Adewola Osunsade, Yael David, Ethel Cesarman, Ari M Melnick, Simone Sidoli, Benjamin A Garcia, Winfried Edelmann, Fernando Macian, Arthur I Skoultchi
H1 histones control the epigenetic landscape by local chromatin compaction. Nature 589 (7841) (2020)
Patrizia Mondello, Saber Tadros, Matthew R Teater, Lorena Fontán, Aaron Y Chang, Neeraj Jain, Haopeng Yang, Shailbala Singh, Hsia-Yuan Ying, Chi-Shuen Chu, Man Chun John Ma, Eneda Toska, Stefan Alig, Matthew Durant, Elisa de Stanchina, Sreejoyee Ghosh, Anja Mottok, Loretta Nastoupil, Sattva S Neelapu, Oliver Weigert, Giorgio Inghirami, José Baselga, Anas Younes, Cassian Yee, Ahmet Dogan, David A Scheinberg, Robert G Roeder, Ari M Melnick, Michael R Green
Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma. Cancer discovery 10 (3) (2020)
Nevin Yusufova, Andreas Kloetgen, Matt Teater, Adewola Osunsade, Jeannie M Camarillo, Christopher R Chin, Ashley S Doane, Bryan J Venters, Stephanie Portillo-Ledesma, Joseph Conway, Jude M Phillip, Olivier Elemento, David W Scott, Wendy Béguelin, Jonathan D Licht, Michael P Snyder, Louis M Staudt, Arthur I Skoultchi, Michael-Christopher Keogh, Effie Apostolou, Christopher E Mason, Marcin Imielinski, Tamar Schlick, Yael David, Aristotelis Tsirigos, C David Allis, Alexey A Soshnev, Ethel Cesarman, Ari M Melnick
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture. Nature 589 (7841) (2020)
Sheng Li, Xiaowen Chen, Jiahui Wang, Cem Meydan, Jacob L Glass, Alan H Shih, Ruud Delwel, Ross L Levine, Christopher E Mason, Ari M Melnick
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML. Cancer discovery 10 (12) (2020)
Wojciech Rosikiewicz, Xiaowen Chen, Pilar M Dominguez, Hussein Ghamlouch, Said Aoufouchi, Olivier A Bernard, Ari M Melnick, Sheng Li
TET2 deficiency reprograms the germinal center B cell epigenome and silences genes linked to lymphomagenesis. Science advances 6 (25) (2020)
Matthew MacKay, Ebrahim Afshinnekoo, Jonathan Rub, Ciaran Hassan, Mihir Khunte, Nithyashri Baskaran, Bryan Owens, Lauren Liu, Gail J Roboz, Monica L Guzman, Ari M Melnick, Shixiu Wu, Christopher E Mason
The therapeutic landscape for cells engineered with chimeric antigen receptors. Nature biotechnology 38 (2) (2020)
Ari M Melnick, Ari M Melnick
An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming? Cancer discovery 9 (9) (2019)
Alessandro Pastore, Federico Gaiti, Sydney X Lu, Ryan M Brand, Scott Kulm, Ronan Chaligne, Hongcang Gu, Kevin Y Huang, Elena K Stamenova, Wendy Béguelin, Yanwen Jiang, Rafael C Schulman, Kyu-Tae Kim, Alicia Alonso, John N Allan, Richard R Furman, Andreas Gnirke, Catherine J Wu, Ari M Melnick, Alexander Meissner, Bradley E Bernstein, Omar Abdel-Wahab, Dan A Landau
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature communications 10 (1) (2019)
Francine E Garrett-Bakelman, Manjula Darshi, Stefan J Green, Ruben C Gur, Ling Lin, Brandon R Macias, Miles J McKenna, Cem Meydan, Tejaswini Mishra, Jad Nasrini, Brian D Piening, Lindsay F Rizzardi, Kumar Sharma, Jamila H Siamwala, Lynn Taylor, Martha Hotz Vitaterna, Maryam Afkarian, Ebrahim Afshinnekoo, Sara Ahadi, Aditya Ambati, Maneesh Arya, Daniela Bezdan, Colin M Callahan, Songjie Chen, Augustine M K Choi, George E Chlipala, Kevin Contrepois, Marisa Covington, Brian E Crucian, Immaculata De Vivo, David F Dinges, Douglas J Ebert, Jason I Feinberg, Jorge A Gandara, Kerry A George, John Goutsias, George S Grills, Alan R Hargens, Martina Heer, Ryan P Hillary, Andrew N Hoofnagle, Vivian Y H Hook, Garrett Jenkinson, Peng Jiang, Ali Keshavarzian, Steven S Laurie, Brittany Lee-McMullen, Sarah B Lumpkins, Matthew MacKay, Mark G Maienschein-Cline, Ari M Melnick, Tyler Maxwell Moore, Kiichi Nakahira, Hemal H Patel, Robert Pietrzyk, Varsha Rao, Rintaro Saito, Denis N Salins, Jan M Schilling, Dorothy D Sears, Caroline K Sheridan, Michael B Stenger, Rakel Tryggvadottir, Alexander Eckehart Urban, Tomas Vaisar, Benjamin Van Espen, Jing Zhang, Michael G Ziegler, Sara R Zwart, John B Charles, Craig E Kundrot, Graham B I Scott, Susan M Bailey, Mathias Basner, Andrew P Feinberg, Stuart M C Lee, Christopher E Mason, Emmanuel Jean-Marie Mignot, Brinda K Rana, Scott M Smith, Michael P Snyder, Fred W Turek
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science (New York, N.Y.) 364 (6436) (2019)
Xabier Agirre, Cem Meydan, Yanwen Jiang, Leire Garate, Ashley S Doane, Zhuoning Li, Akanksha Verma, Bruno Paiva, José I Martín-Subero, Olivier Elemento, Christopher E Mason, Felipe Prosper, Ari M Melnick
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response. Nature communications 10 (1) (2019)
David Sermer, Laura Pasqualucci, Hans-Guido Wendel, Ari M Melnick, Anas Younes
Emerging epigenetic-modulating therapies in lymphoma. Nature reviews. Clinical oncology 16 (8) (2019)
Coraline Mlynarczyk, Lorena Fontán, Ari M Melnick
Germinal center-derived lymphomas: The darkest side of humoral immunity. Immunological reviews 288 (1) (2019)
Marién Pascual, María Mena-Varas, Eloy Francisco Robles, Maria-Jose Garcia-Barchino, Carlos Panizo, Sandra Hervás-Stubbs, Diego Alignani, Ainara Sagardoy, Jose Ignacio Martinez-Ferrandis, Karen L Bunting, Stephen Meier, Xavier Sagaert, Davide Bagnara, Elisabeth Guruceaga, Oscar Blanco, Jon Celay, Alvaro Martínez-Baztan, Noelia Casares, Juan Jose Lasarte, Thomas MacCarthy, Ari M Melnick, Jose-Angel Martinez-Climent, Sergio Roa
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas. Blood 133 (22) (2019)
Katerina Hatzi, Huimin Geng, Ashley S Doane, Cem Meydan, Reed LaRiviere, Mariano Cardenas, Cihangir Duy, Hao Shen, Maria Nieves Calvo Vidal, Timour Baslan, Helai P Mohammad, Ryan G Kruger, Rita Shaknovich, Ann M Haberman, Giorgio Inghirami, Scott W Lowe, Ari M Melnick
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nature immunology 20 (1) (2018)
Nakhle S Saba, Delong Liu, Sarah E M Herman, Chingiz Underbayev, Xin Tian, David Behrend, Marc A Weniger, Martin Skarzynski, Jennifer Gyamfi, Lorena Fontan, Ari M Melnick, Cliona Grant, Mark Roschewski, Alba Navarro, Sílvia Beà, Stefania Pittaluga, Kieron Dunleavy, Wyndham H Wilson, Adrian Wiestner
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma. Blood 128 (1) (2016)

Ari M Melnick.css-eqlu8i{font-size:small;padding-left:4px;} (Ari Melnick, Meng Li, A Melnick)

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Ari M Melnick (Ari Melnick, Meng Li, A Melnick)