Jonathan J Keats (Jonathan Keats, Johnathan Keats, J Jonathan Keats)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 29

Top Venues

Leukemia

Blood cancer journal

Nature communications

Blood cancer discovery

Translational Genomics Research Institute

University of Alberta (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Translational Genomics Research Institute Jul 15 2010

United States

Director of Bioinformatics / Assistant Professor :: Integrated Cancer Genomics

Mayo Clinic Sep 15 2005 - Jul 15 2010

United States

Research Fellow

Education History

University of Alberta Jan 01 1999 - Aug 31 2005

Canada

PHD :: Oncology

University of Alberta Sep 01 1995 - Apr 15 1999

Canada

BSC :: Genetics

Publications

Sheri Skerget, Daniel Penaherrera, Ajai Chari, Sundar Jagannath, David S Siegel, Ravi Vij, Gregory Orloff, Andrzej Jakubowiak, Ruben Niesvizky, Darla K Liles, Jesus G Berdeja, Moshe Levy, Jeffrey Wolf, Saad Z Usmani, null null, Austin W Christofferson, Sara Nasser, Jessica L Aldrich, Christophe Legendre, Brooks A Benard, Chase Miller, Bryce Turner, Ahmet Kurdoglu, Megan Washington, Venkata D Yellapantula, Jonathan R Adkins, Lori Cuyugan, Martin Boateng, Adrienne Helland, Shari Kyman, Jackie McDonald, Rebecca Reiman, Kristi Stephenson, Erica Tassone, Alex Blanski, Brianne Livermore, Meghan Kirchhoff, Daniel C Rohrer, Mattia D'Agostino, Manuela Gamella, Kimberly Collison, Jennifer Stumph, Pam Kidd, Andrea Donnelly, Barbara Zaugg, Maureen Toone, Kyle McBride, Mary DeRome, Jennifer Rogers, David Craig, Winnie S Liang, Norma C Gutiérrez, Scott D Jewell, John Carpten, Kenneth C Anderson, Hearn Jay Cho, Daniel Auclair, Sagar Lonial, Jonathan J Keats
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes. Nature genetics (2024)
Holly Lee, Sungwoo Ahn, Ranjan Maity, Noemie Leblay, Bachisio Ziccheddu, Marietta Truger, Monika Chojnacka, Anthony Cirrincione, Michael A Durante, Remi Tilmont, Elie Barakat, Mansour Poorebrahim, Sarthak Sinha, John McIntyre, Angela M Y Chan, Holly Wilson, Shari Kyman, Amrita Krishnan, Carl Ola Landgren, Wencke Walter, Manja Meggendorfer, Claudia Haferlach, Torsten Haferlach, Hermann Einsele, Klaus Martin Kortüm, Stefan Knop, Jean Baptiste Alberge, Andreas Rosenwald, Jonathan J Keats, Leo Rasche, Francesco Maura, Paola Neri, Nizar J Bahlis
Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma. Nature medicine (2023)
Enze Liu, Nathan Becker, Parvathi Sudha, Chuanpeng Dong, Yunlong Liu, Jonathan J Keats, Gareth Morgan, Brian A Walker
Alternative splicing in multiple myeloma is associated with the non-homologous end joining pathway. Blood cancer journal 13 (1) (2023)
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick, Vilas A Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M Meyers, Jordan G Bryan, Neekesh V Dharia, Paul J Hengeveld, Johanna B Brüggenthies, Huihui Tang, Andrew J Aguirre, Quinlan L Sievers, Benjamin L Ebert, Brian J Glassner, Christopher J Ott, James E Bradner, Nicholas P Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J Keats, Richard W J Groen, Nathanael S Gray, Aedin C Culhane, James M McFarland, Joshua M Dempster, Jonathan D Licht, Lawrence H Boise, William C Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S Mitsiades
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature cancer 4 (5) (2023)
Paola Neri, Benjamin G Barwick, David Jung, Jonathan C Patton, Ranjan Maity, Ines Tagoug, Caleb K Stein, Rémi Tilmont, Noemie Leblay, Sungwoo Ahn, Holly Lee, Seth J Welsh, Daniel L Riggs, Nicholas Stong, Erin Flynt, Anjan Thakurta, Jonathan J Keats, Sagar Lonial, Peter Leif Bergsagel, Lawrence H Boise, Nizar J Bahlis
ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma. Blood cancer discovery (2023)
Enze Liu, Nathan Becker, Parvathi Sudha, Chuanpeng Dong, Yunlong Liu, Jonathan J Keats, Gareth Morgan, Brian A Walker
Alternative splicing in multiple myeloma is associated with the non-homologous end joining pathway. Blood cancer journal 13 (1) (2023)
Enze Liu, Nathan Becker, Parvathi Sudha, Chuanpeng Dong, Yunlong Liu, Jonathan J Keats, Gareth Morgan, Brian A Walker
Alternative splicing in multiple myeloma is associated with the non-homologous end joining pathway. Blood cancer journal 13 (1) (2023)
Tarek H Mouhieddine, Chidimma Nzerem, Robert A Redd, Andrew Dunford, Matthew Joseph Leventhal, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Habib El-Khoury, David P Steensma, Benjamin L Ebert, Robert J Soiffer, Jonathan J Keats, Shaadi Mehr, Daniel Auclair, Irene M Ghobrial, Adam S Sperling, Chip Stewart, Gad A Getz
Clinical outcomes and evolution of clonal hematopoiesis in patients with newly diagnosed multiple myeloma. Cancer research communications (2023)
Faith E Davies, Charlotte Pawlyn, Saad Z Usmani, Jesús San F Miguel, Hermann Einsele, Eileen Mary Boyle, Jill Corre, Daniel Auclair, Hearn Jay Cho, Sagar Lonial, Pieter Sonneveld, A Keith Stewart, Peter Leif Bergsagel, Martin F Kaiser, Katja Weisel, Jonathan J Keats, Joseph R Mikhael, Kathryn E Morgan, Irene M Ghobrial, Robert Z Orlowski, Carl Ola Landgren, Francesca Gay, Joseph Caers, Wee-Joo Chng, Ajai Chari, Brian A Walker, Shaji K Kumar, Luciano José Megale Costa, Kenneth C Anderson, Gareth J Morgan
Perspectives on the Risk-Stratified Treatment of Multiple Myeloma. Blood cancer discovery 3 (4) (2022)
Georgina S F Anderson, José Ballester Beltrán, George Giotopoulos, Jose A Guerrero, Sylvanie Surget, James C Williamson, Tsz So, David Bloxham, Anna Aubareda, Ryan J Asby, Ieuan Walker, Lesley Jenkinson, Elizabeth J Soilleux, James P Roy, Ana Teodosio, Catherine Ficken, Leah Officer, Sara Nasser, Sheri Skerget, Jonathan J Keats, Peter Greaves, Yu-Tzu Tai, Kenneth C Anderson, Marion MacFarlane, James E D Thaventhiran, Brian James Patrick Huntly, Paul J Lehner, Michael A Chapman
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma. Blood 139 (16) (2022)
Signy Chow, Olena Kis, David T Mulder, Arnavaz Danesh, Jeff Bruce, Ting Ting Wang, Donna Reece, Nizar Bhalis, Paola Neri, Peter J B Sabatini, Jonathan J Keats, Suzanne Trudel, Trevor J Pugh
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. Life science alliance 6 (1) (2022)
Timothy Cody Ashby, Eileen Mary Boyle, Michael A Bauer, Aneta Mikulasova, Christopher Paul Wardell, Louis Williams, Ariel Siegel, Patrick Blaney, Marc Braunstein, David Kaminetsky, Jonathan J Keats, Francesco Maura, Carl Ola Landgren, Brian A Walker, Faith E Davies, Gareth J Morgan
Structural variants shape the genomic landscape and clinical outcome of multiple myeloma. Blood cancer journal 12 (5) (2022)
Benjamin G Barwick, Vilas A Gupta, Shannon M Matulis, Jonathan C Patton, Doris R Powell, Yanyan Gu, David L Jaye, Karen N Conneely, Yin C Lin, Craig C Hofmeister, Ajay K Nooka, Jonathan J Keats, Sagar Lonial, Paula M Vertino, Lawrence H Boise
Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (11) (2021)
Eileen M Boyle, Louis Williams, Patrick Blaney, Timothy Cody Ashby, Michael A Bauer, Brian A Walker, Hussein Ghamlouch, Jinyoung Choi, Emeline Perrial, Yubao Wang, Jessica Caro, James H Stoeckle, Arnaldo Arbini, David Kaminetzky, Marc Braunstein, Benedetto Bruno, Beatrice Razzo, Benjamin T Diamond, Kylee H Maclachlan, Francesco Maura, Carl Ola Landgren, Rachel Litke, Christopher D Fegan, Jonathan J Keats, Daniel Auclair, Faith E Davies, Gareth J Morgan
Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length. Leukemia (2021)
Li Tai Fang, Bin Zhu, Yongmei Zhao, Wanqiu Chen, Zhao-Wei Yang, Liz Kerrigan, Kurt Langenbach, Maryellen de Mars, Charles Lu, Kenneth Idler, Howard Jacob, Yuanting Zheng, Luyao Ren, Ying Yu, Erich Jaeger, Gary P Schroth, Ogan D Abaan, Keyur Talsania, Justin Lack, Tsai-Wei Shen, Zhong Chen, Seta Stanbouly, Bao Tran, Jyoti Shetty, Yuliya Kriga, Daoud Meerzaman, Cu Nguyen, Virginie Petitjean, Marc Sultan, Margaret Cam, Monika Mehta, Tiffany Hung, Eric Peters, Rasika Kalamegham, Sayed Mohammad Ebrahim Sahraeian, Marghoob Mohiyuddin, Yunfei Guo, Lijing Yao, Lei Song, Hugo Y K Lam, Jiri Drabek, Petr Vojta, Roberta Maestro, Daniela Gasparotto, Sulev Kõks, Ene Reimann, Andreas Scherer, Jessica Nordlund, Ulrika Liljedahl, Roderick V Jensen, Mehdi Pirooznia, Zhipan Li, Chunlin Xiao, Stephen T Sherry, Rebecca Kusko, Malcolm Moos, Eric Donaldson, Zivana Tezak, Baitang Ning, Weida Tong, Jing Li, Penelope Duerken-Hughes, Claudia Catalanotti, Shamoni Maheshwari, Joe Shuga, Winnie S Liang, Jonathan J Keats, Jonathan Adkins, Erica Tassone, Victoria Zismann, Timothy McDaniel, Jeffery M Trent, Jonathan Foox, Daniel Butler, Christopher E Mason, Huixiao Hong, Le-Ming Shi, Charles Wang, Wenming Xiao, null null
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing. Nature biotechnology 39 (9) (2021)
Sherry Bhalla, David T Melnekoff, Adolfo Aleman, Violetta V Leshchenko, Paula Restrepo, Jonathan J Keats, Kenan Onel, Jeffrey R Sawyer, Deepu Madduri, Joshua Richter, Shambavi Richard, Ajai Chari, Hearn Jay Cho, Joel T Dudley, Sundar Jagannath, Alessandro Lagana, Samir S Parekh
Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications. Science advances 7 (47) (2021)
Vilas A Gupta, Benjamin G Barwick, Shannon M Matulis, Ryosuke Shirasaki, David L Jaye, Jonathan J Keats, Benjamin Oberlton, Nisha S Joseph, Craig C Hofmeister, Leonard T Heffner, Madhav V Dhodapkar, Ajay K Nooka, Sagar Lonial, Constantine S Mitsiades, Jonathan L Kaufman, Lawrence H Boise
Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression. Blood 137 (26) (2021)
Sara A Byron, William P D Hendricks, Abhinav B Nagulapally, Jacqueline M Kraveka, William S Ferguson, Valerie I Brown, Don E Eslin, Deanna Mitchell, Albert Cornelius, William Roberts, Michael S Isakoff, Javier E Oesterheld, Randal K Wada, Jawhar Rawwas, Kathleen Neville, Peter E Zage, Virginia L Harrod, Genevieve Bergendahl, Elizabeth VanSickle, Karl Dykema, Jeffrey Bond, Hsien-Chao Chou, Jun S Wei, Xinyu Wen, Hue V Reardon, Alison Roos, Sara Nasser, Tyler Izatt, Daniel Enriquez, Apurva M Hegde, Faith Cisneros, Austin Christofferson, Bryce Turner, Szabolcs Szelinger, Jonathan J Keats, Rebecca F Halperin, Javed Khan, Giselle L Saulnier Sholler, Jeffery M Trent
Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion. Cancer research 81 (23) (2021)
Linda B Baughn, Zhuo Li, Kathryn Pearce, Celine M Vachon, Mei-Yin Polley, Jonathan J Keats, Eran Elhaik, Michael Baird, Terry Therneau, James R Cerhan, Peter Leif Bergsagel, Angela Dispenzieri, Sundararajan Vincent Rajkumar, Yan W Asmann, Shaji K Kumar
The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias. Blood cancer journal 10 (3) (2020)
Mattia D'Agostino, Gian Maria Zaccaria, Bachisio Ziccheddu, Even Holth Rustad, Elisa Genuardi, Andrea Capra, Stefania Oliva, Daniel Auclair, Jennifer Yesil, Paola Colucci, Jonathan J Keats, Manuela Gambella, Sara Bringhen, Alessandra Larocca, Mario Boccadoro, Niccolo' Bolli, Francesco Maura, Francesca Gay
Early Relapse Risk in Patients with Newly Diagnosed Multiple Myeloma Characterized by Next-generation Sequencing. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (18) (2020)
Domenico Viola, Ada Dona, Enrico Caserta, Estelle Troadec, Francesca Besi, Tinisha McDonald, Lucy Ghoda, Emine Gulsen Gunes, James F Sanchez, Jihane Khalife, Marianna Martella, Chatchada Karanes, Myo Htut, Xiuli Wang, Michael Rosenzweig, Arnab Chowdhury, Douglas Sborov, Rodney R Miles, Paul J Yazaki, Todd Ebner, Craig C Hofmeister, Stephen J Forman, Steven T Rosen, Guido Marcucci, John Shively, Jonathan J Keats, Amrita Krishnan, Flavia Pichiorri
Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting. Leukemia 35 (1) (2020)
Tarek H Mouhieddine, Adam S Sperling, Robert A Redd, Jihye Park, Matthew Leventhal, Christopher J Gibson, Salomon Manier, Amin H Nassar, Marzia Capelletti, Daisy Huynh, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Kalvis Hornburg, Henry Dumke, Muhieddine M Itani, Cody J Boehner, Chia-Jen Liu, Saud H AlDubayan, Brendan Reardon, Eliezer M Van Allen, Jonathan J Keats, Chip Stewart, Shaadi Mehr, Daniel Auclair, Robert L Schlossman, Nikhil C Munshi, Kenneth C Anderson, David P Steensma, Jacob P Laubach, Paul G Richardson, Jerome Ritz, Benjamin L Ebert, Robert J Soiffer, Lorenzo Trippa, Gad A Getz, Donna S Neuberg, Irene M Ghobrial
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nature communications 11 (1) (2020)
Joseph Longo, Petr Smirnov, Zhihua Li, Emily Branchard, Jenna E van Leeuwen, Jonathan D Licht, Benjamin Haibe-Kains, David William Andrews, Jonathan J Keats, Trevor J Pugh, Suzanne Trudel, Linda Z Penn
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma. Leukemia 35 (3) (2020)
Benjamin G Barwick, Paola Neri, Nizar J Bahlis, Ajay K Nooka, Madhav V Dhodapkar, David L Jaye, Craig C Hofmeister, Jonathan L Kaufman, Vikas A Gupta, Daniel Auclair, Jonathan J Keats, Sagar Lonial, Paula M Vertino, Lawrence H Boise
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis. Nature communications 10 (1) (2019)
Juan-José Garcés, Michal Simicek, Marco Vicari, Lucie Brozova, Leire Burgos, Renata Bezdekova, Diego Alignani, Maria-Jose Calasanz, Katerina Growkova, Ibai Goicoechea, Xabier Agirre, Ludek Pour, Felipe Prosper, Rafael Rios, Joaquin Martinez-Lopez, Pamela Millacoy, Luis Palomera, Rafael A Del Orbe, Albert Perez-Montaña, Sonia Garate, Laura Blanco, Marta Lasa, Patricia Maiso, Juan Flores-Montero, Luzalba Sanoja-Flores, Zuzana Chyra, Alexander Vdovin, Tereza Sevcikova, Tomas Jelinek, Cirino Botta, Halima El Omri, Jonathan J Keats, Alberto Orfao, Roman Hajek, Jesus F San-Miguel, Bruno Paiva
Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination. Leukemia 34 (2) (2019)
Kristine Misund, Niamh Keane, Caleb K Stein, Yan W Asmann, Grady Day, Seth Welsh, Scott A Van Wier, Daniel L Riggs, Greg Ahmann, Marta Chesi, David S Viswanatha, Shaji K Kumar, Angela Dispenzieri, Veronica Gonzalez-Calle, Robert A Kyle, Michael O'Dwyer, S Vincent Rajkumar, K Martin Kortüm, Jonathan J Keats, null null, Rafael Fonseca, A Keith Stewart, W Michael Kuehl, Esteban Braggio, Peter Leif Bergsagel
MYC dysregulation in the progression of multiple myeloma. Leukemia 34 (1) (2019)
Brian A Walker, Konstantinos Mavrommatis, Christopher P Wardell, T Cody Ashby, Michael A Bauer, Faith Davies, Adam Rosenthal, Hongwei Wang, Pingping Qu, Antje Hoering, Mehmet Samur, Fadi Towfic, Maria Ortiz, Erin Flynt, Zhinuan Yu, Zhihong Yang, Dan Rozelle, John Obenauer, Matthew Trotter, Daniel Auclair, Jonathan J Keats, Niccolo Bolli, Mariateresa Fulciniti, Raphael Szalat, Phillipe Moreau, Brian Durie, A Keith Stewart, Hartmut Goldschmidt, Marc S Raab, Hermann Einsele, Pieter Sonneveld, Jesus San Miguel, Sagar Lonial, Graham H Jackson, Kenneth C Anderson, Herve Avet-Loiseau, Nikhil Munshi, Anjan Thakurta, Gareth Morgan
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis. Leukemia 33 (1) (2018)
Jayeeta Ghose, Domenico Viola, Cesar Terrazas, Enrico Caserta, Estelle Troadec, Jihane Khalife, Emine Gulsen Gunes, James Sanchez, Tinisha McDonald, Guido Marcucci, Balveen Kaur, Michael Rosenzweig, Jonathan J Keats, Steven Rosen, Amrita Krishnan, Abhay R Satoskar, Craig C Hofmeister, Flavia Pichiorri
Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology 7 (10) (2018)
Zarko Manojlovic, Austin Christofferson, Winnie S Liang, Jessica Aldrich, Megan Washington, Shukmei Wong, Daniel C Rohrer, Scott Jewell, Rick A Kittles, Mary Derome, Daniel Auclair, David Wesley Craig, Jonathan J Keats, John D Carpten
Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases. PLoS genetics 13 (11) (2017)

Jonathan J Keats.css-eqlu8i{font-size:small;padding-left:4px;} (Jonathan Keats, Johnathan Keats, J Jonathan Keats)

Publication Activity (10 Years)

Top Topics

Top Venues

Jonathan J Keats (Jonathan Keats, Johnathan Keats, J Jonathan Keats)