Jacob T Bush (Jacob Bush)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 29

Top Topics

Trypanosoma Cruzi

Protein Protein

Top Venues

ACS chemical biology

Communications chemistry

Angewandte Chemie (International ed. in English)

RSC medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F Ashraf, Elvin Dominic de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T Bush, György Miklós Keserű
Mapping protein binding sites by photoreactive fragment pharmacophores. Communications chemistry 7 (1) (2024)
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F Ashraf, Elvin Dominic de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T Bush, György Miklós Keserű
Mapping protein binding sites by photoreactive fragment pharmacophores. Communications chemistry 7 (1) (2024)
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Shriram Bhosle, Kieron May, Carmen Herranz, Samantha J Walker, Raynold Shenje, Cansu Dincer, Freddy Gibson, Ruby Banerjee, Zoe Hewitson, Thilo Werner, Joshua E Cottom, Yang Peng, Nanhua Deng, Youyou Zhang, Eldridge N Nartey, Leng Nickels, Philip Landis, Daniela Conticelli, Katrina McCarten, Jacob T Bush, Mamta Sharma, Howard Lightfoot, David House, Emma Milford, Emma K Grant, Michal P Glogowski, Craig D Wagner, Marcus Bantscheff, Anna Rutkowska-Klute, null null, Francesca Zappacosta, Jonathan Pettinger, Syd Barthorpe, H Christian Eberl, Brian T Jones, Jessica L Schneck, Dennis J Murphy, Emile E Voest, Joshua P Taygerly, Michael P DeMartino, Matthew A Coelho, Jonathan Houseley, Geeta Sharma, Benjamin J Schwartz, Mathew J Garnett
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells. Cancer discovery 14 (8) (2024)
Catherine A Hurd, Jacob T Bush, Andrew J Powell, Louise J Walport
mRNA Display in Cell Lysates Enables Identification of Cyclic Peptides Targeting the BRD3 Extraterminal Domain. Angewandte Chemie (International ed. in English) (2024)
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F Ashraf, Elvin Dominic de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T Bush, György Miklós Keserű
Mapping protein binding sites by photoreactive fragment pharmacophores. Communications chemistry 7 (1) (2024)
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F Ashraf, Elvin Dominic de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T Bush, György Miklós Keserű
Mapping protein binding sites by photoreactive fragment pharmacophores. Communications chemistry 7 (1) (2024)
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Shriram Bhosle, Kieron May, Carmen Herranz, Samantha J Walker, Raynold Shenje, Cansu Dincer, Freddy Gibson, Ruby Banerjee, Zoe Hewitson, Thilo Werner, Joshua E Cottom, Yang Peng, Nanhua Deng, Philip Landis, Daniela Conticelli, Katrina McCarten, Jacob T Bush, Mamta Sharma, Howard Lightfoot, David House, Emma Milford, Emma K Grant, Michal P Glogowski, Craig D Wagner, Marcus Bantscheff, Anna Rutkowska-Klute, Cell Model Network Uk Group, Francesca Zappacosta, Jonathan Pettinger, Syd Barthorpe, H Christian Eberl, Brian T Jones, Jessica L Schneck, Dennis J Murphy, Emile E Voest, Joshua P Taygerly, Michael P DeMartino, Matthew A Coelho, Jonathan Houseley, Geeta Sharma, Benjamin J Schwartz, Mathew J Garnett
Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells. Cancer discovery (2024)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology 18 (2) (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology (2023)
Arron Aatkar, Aini Vuorinen, Oliver E Longfield, Katharine Gilbert, Rachel Peltier-Heap, Craig D Wagner, Francesca Zappacosta, Katrin Rittinger, Chun-Wa Chung, David House, Nicholas C O Tomkinson, Jacob T Bush
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments. ACS chemical biology (2023)
Arron Aatkar, Aini Vuorinen, Oliver E Longfield, Katharine Gilbert, Rachel Peltier-Heap, Craig D Wagner, Francesca Zappacosta, Katrin Rittinger, Chun-Wa Chung, David House, Nicholas C O Tomkinson, Jacob T Bush
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments. ACS chemical biology (2023)
Ross P Thomas, Emma K Grant, Eleanor R Dickinson, Francesca Zappacosta, Lee J Edwards, Michael M Hann, David House, Nicholas C O Tomkinson, Jacob T Bush
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry. RSC medicinal chemistry 14 (4) (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology 18 (2) (2023)
Arron Aatkar, Aini Vuorinen, Oliver E Longfield, Katharine Gilbert, Rachel Peltier-Heap, Craig D Wagner, Francesca Zappacosta, Katrin Rittinger, Chun-Wa Chung, David House, Nicholas C O Tomkinson, Jacob T Bush
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments. ACS chemical biology (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology 18 (2) (2023)
Catherine N Russell, Jennifer L Carter, Juliet M Borgia, Jacob T Bush, Félix Calderón, Raquel Gabarró, Stuart J Conway, Jeremy Charles Mottram, Anthony J Wilkinson, Nathaniel G Jones
Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery. ACS infectious diseases (2023)
Adam M Thomas, Marta Serafini, Emma K Grant, Edward A J Coombs, Joseph P Bluck, Matthias Schiedel, Michael A McDonough, Jessica K Reynolds, Bernadette Lee, Michael Platt, Vassilena Sharlandjieva, Philip Charles Biggin, Fernanda Duarte, Thomas A Milne, Jacob T Bush, Stuart J Conway
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation. ACS chemical biology (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology 18 (2) (2023)
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, Peter Pogány, Jonathan Pettinger, Emma K Grant, Joanna M Kirkpatrick, Katrin Rittinger, David House, Glenn A Burley, Jacob T Bush
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS chemical biology 18 (2) (2023)
Arron Aatkar, Aini Vuorinen, Oliver E Longfield, Katharine Gilbert, Rachel Peltier-Heap, Craig D Wagner, Francesca Zappacosta, Katrin Rittinger, Chun-Wa Chung, David House, Nicholas C O Tomkinson, Jacob T Bush
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments. ACS chemical biology (2023)
Ross P Thomas, Emma K Grant, Eleanor R Dickinson, Francesca Zappacosta, Lee J Edwards, Michael M Hann, David House, Nicholas C O Tomkinson, Jacob T Bush
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry. RSC medicinal chemistry 14 (4) (2023)
Emma Campbell, Andrea Taladriz-Sender, Olivia I Paisley, Alan R Kennedy, Jacob T Bush, Glenn A Burley
A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes. The Journal of organic chemistry 87 (7) (2022)
Ross P Thomas, Rachel E Heap, Francesca Zappacosta, Emma K Grant, Peter Pogány, Stephen Besley, David J Fallon, Michael M Hann, David House, Nicholas C O Tomkinson, Jacob T Bush
A direct-to-biology high-throughput chemistry approach to reactive fragment screening. Chemical science 12 (36) (2021)
Anna Cioce, Ganka Bineva-Todd, Anthony J Agbay, Junwon Choi, Thomas M Wood, Marjoke F Debets, William M Browne, Holly L Douglas, Chloe Roustan, Omur Y Tastan, Svend Kjaer, Jacob T Bush, Carolyn R Bertozzi, Benjamin Schumann
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS chemical biology 16 (10) (2021)
Jacob T Bush, Peter Pogány, Stephen D Pickett, Mike Barker, Andrew Baxter, Sebastien Campos, Anthony W J Cooper, David J Hirst, Graham Inglis, Alan Nadin, Vipulkumar K Patel, Darren Poole, John Pritchard, Yoshiaki Washio, Gemma White, Darren V S Green
A Turing Test for Molecular Generators. Journal of medicinal chemistry 63 (20) (2020)
Emma K Grant, David J Fallon, Michael M Hann, Ken G M Fantom, Chad Quinn, Francesca Zappacosta, Roland S Annan, Chun-Wa Chung, Paul Bamborough, David P Dixon, Peter Stacey, David House, Vipulkumar K Patel, Nicholas C O Tomkinson, Jacob T Bush
A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands. Angewandte Chemie (International ed. in English) 59 (47) (2020)
Emma K Grant, David J Fallon, H Christian Eberl, Ken G M Fantom, Francesca Zappacosta, Cassie Messenger, Nicholas C O Tomkinson, Jacob T Bush
A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family. Angewandte Chemie (International ed. in English) 58 (48) (2019)