Jamie B Spangler (Jamie Spangler)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 41

Top Venues

PLoS computational biology

bioRxiv : the preprint server for biology

Current protocols

Journal of immunology (Baltimore, Md. : 1950)

Johns Hopkins University

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Johns Hopkins University Jul 01 2017

United States

Assistant Professor :: Biomedical Engineering and Chemical & Biomolecular Engineering

Stanford University

United States

Postdoctoral Scholar :: Molecular & Cellular Physiology

National Institute of Allergy and Infectious Diseases

United States

Post-Baccalaureate Research Fellow :: Molecular Virology

Education History

Massachusetts Institute of Technology

United States

PHD :: Biological Engineering

Johns Hopkins University

United States

BSC :: Biomedical Engineering

Publications

Jakub Tomala, Shanelle D Cao, Jamie B Spangler
Engineering Anticytokine Antibodies for Immune Modulation. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Charina S Fabilane, A Carson Stephenson, Elissa K Leonard, Derek VanDyke, Jamie B Spangler
Cytokine/Antibody Fusion Protein Design and Evaluation. Current protocols 4 (5) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Charina S Fabilane, A Carson Stephenson, Elissa K Leonard, Derek VanDyke, Jamie B Spangler
Cytokine/Antibody Fusion Protein Design and Evaluation. Current protocols 4 (5) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Jakub Tomala, Shanelle D Cao, Jamie B Spangler
Engineering Anticytokine Antibodies for Immune Modulation. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Charina S Fabilane, A Carson Stephenson, Elissa K Leonard, Derek VanDyke, Jamie B Spangler
Cytokine/Antibody Fusion Protein Design and Evaluation. Current protocols 4 (5) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. PLoS computational biology 20 (6) (2024)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Aliyah B Silver, Jeremy Wang, Jamie B Spangler
Masking T cell engagers mitigates on-target off-tumor activity. Nature cancer (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Luke M Tomasovic, Kathy Liu, Derek VanDyke, Charina S Fabilane, Jamie B Spangler
Molecular Engineering of Interleukin-2 for Enhanced Therapeutic Activity in Autoimmune Diseases. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Jeroen Deckers, Tom Anbergen, Ayla M Hokke, Anne de Dreu, David P Schrijver, Koen de Bruin, Yohana C Toner, Thijs J Beldman, Jamie B Spangler, Tom F A de Greef, Francesca Grisoni, Roy van der Meel, Leo A B Joosten, Maarten Merkx, Mihai G Netea, Willem J M Mulder
Engineering cytokine therapeutics. Nature reviews bioengineering 1 (4) (2023)
Zachary J Bernstein, Anjali Shenoy, Amy Chen, Nicola M Heller, Jamie B Spangler
Engineering the IL-4/IL-13 axis for targeted immune modulation. Immunological reviews (2023)
Kelly R Rhodes, Stephany Y Tzeng, Marcos Iglesias Lozano, Dongwoo Lee, Kaitlyn Storm, Sarah Y Neshat, Derek VanDyke, Shirley M Lowmaster, Jamie B Spangler, Giorgio Raimondi, Jordan J Green
Bioengineered particles expand myelin-specific regulatory T cells and reverse autoreactivity in a mouse model of multiple sclerosis. Science advances 9 (22) (2023)
Christina M P Ray, Huilin Yang, Jamie B Spangler, Feilim Mac Gabhann
Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors. bioRxiv : the preprint server for biology (2023)
Arbor G Dykema, Jiajia Zhang, Laurene S Cheung, Sydney Connor, Boyang Zhang, Zhen Zeng, Christopher M Cherry, Taibo Li, Justina X Caushi, Marni Nishimoto, Andrew J Munoz, Zhicheng Ji, Wenpin Hou, Wentao Zhan, Dipika Singh, Tianbei Zhang, Rufiaat Rashid, Marisa Mitchell-Flack, Sadhana Bom, Ada Tam, Nick Ionta, Thet H K Aye, Yi Wang, Camille A Sawosik, Lauren E Tirado, Luke M Tomasovic, Derek VanDyke, Jamie B Spangler, Valsamo Anagnostou, Stephen Yang, Jonathan D Spicer, Roni Rayes, Janis M Taube, Julie R Brahmer, Patrick M Forde, Srinivasan Yegnasubramanian, Hongkai Ji, Drew M Pardoll, Kellie N Smit
Lung tumor-infiltrating T reg have divergent transcriptional profiles and function linked to checkpoint blockade response. Science immunology 8 (87) (2023)
Huilin Yang, Umut Y Ulge, Alfredo Quijano-Rubio, Zachary J Bernstein, David R Maestas, Jung-Ho Chun, Wentao Wang, Jian-Xin Lin, Kevin M Jude, Srujan Singh, Brian T Orcutt-Jahns, Peng Li, Jody Mou, Liam Chung, Yun-Huai Kuo, Yasmin H Ali, Aaron S Meyer, Warren L Grayson, Nicola M Heller, K Christopher Garcia, Warren J Leonard, Daniel Adriano Silva, Jennifer H Elisseeff, Julien S Baker, Jamie B Spangler
Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds. Nature chemical biology (2023)
Paul R Sargunas, Jamie B Spangler
Joined at the hip: The role of light chain complementarity determining region 2 in antibody self-association. Proceedings of the National Academy of Sciences of the United States of America 119 (28) (2022)
Monika Kizerwetter, Kevin Pietz, Luke M Tomasovic, Jamie B Spangler
Empowering gene delivery with protein engineering platforms. Gene therapy (2022)
Ariel Isser, Aliyah B Silver, Hawley C Pruitt, Michal Mass, Emma H Elias, Gohta Aihara, Si-Sim Kang, Niklas Bachmann, Ying-Yu Chen, Elissa K Leonard, Joan G Bieler, Worarat Chaisawangwong, Joseph Choy, Sydney R Shannon, Sharon Gerecht, Jeffrey S Weber, Jamie B Spangler, Jonathan P Schneck
Nanoparticle-based modulation of CD4 + T cell effector and helper functions enhances adoptive immunotherapy. Nature communications 13 (1) (2022)
Monika Kizerwetter, Kevin Pietz, Luke M Tomasovic, Jamie B Spangler
Empowering gene delivery with protein engineering platforms. Gene therapy (2022)
Seth D Ludwig, Zachary J Bernstein, Christian Agatemor, Kris Dammen-Brower, Jeffrey Ruffolo, Jonah M Rosas, Jeremy D Post, Robert N Cole, Kevin J Yarema, Jamie B Spangler
A versatile design platform for glycoengineering therapeutic antibodies. mAbs 14 (1) (2022)
Elissa K Leonard, Miguel Aller Pellitero, Boris Juelg, Jamie B Spangler, Netzahualcóyotl Arroyo-Currás
Antibody-Invertase Fusion Protein Enables Quantitative Detection of SARS-CoV-2 Antibodies Using Widely Available Glucometers. Journal of the American Chemical Society 144 (25) (2022)
Joseph de Rutte, Robert Dimatteo, Maani M Archang, Mark van Zee, Doyeon Koo, Sohyung Lee, Allison C Sharrow, Patrick J Krohl, Michael Mellody, Sheldon Zhu, James V Eichenbaum, Monika Kizerwetter, Shreya Udani, Kyung Ha, Richard C Willson, Andrea L Bertozzi, Jamie B Spangler, Robert Damoiseaux, Dino Di Carlo
Suspendable Hydrogel Nanovials for Massively Parallel Single-Cell Functional Analysis and Sorting. ACS nano 16 (5) (2022)
Alfredo Quijano-Rubio, Aladdin M Bhuiyan, Huilin Yang, Isabel Leung, Elisa Bello, Lestat R Ali, Kevin Zhangxu, Jilliane Bruffey, Jung-Ho Chun, Wentao Wang, Marc J Lajoie, Rashmi Ravichandran, Yun-Huai Kuo, Stephanie K Dougan, Stanley R Riddell, Jamie B Spangler, Michael Dougan, Daniel Adriano Silva, Julien S Baker
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy. Nature biotechnology (2022)
Kathryn M Luly, Huilin Yang, Stephen J Lee, Wentao Wang, Seth D Ludwig, Haley E Tarbox, David R Wilson, Jordan J Green, Jamie B Spangler
Poly(Beta-Amino Ester)s as High-Yield Transfection Reagents for Recombinant Protein Production. International journal of nanomedicine 17 (2022)
Paul R Sargunas, Jamie B Spangler
Full speed AHEAD in antibody discovery. Nature chemical biology 17 (10) (2021)
Huilin Yang, Yun-Huai Kuo, Zion I Smith, Jamie B Spangler
Targeting cancer metastasis with antibody therapeutics. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 13 (4) (2021)
Rakeeb Kureshi, Angela Zhu, Jikui Shen, Stephany Y Tzeng, Leilani R Astrab, Paul R Sargunas, Jordan J Green, Peter A Campochiaro, Jamie B Spangler
Structure-Guided Molecular Engineering of a Vascular Endothelial Growth Factor Antagonist to Treat Retinal Diseases. Cellular and molecular bioengineering 13 (5) (2020)
Livia A Casciola-Rosen, David R Thiemann, Felipe Andrade, Maria Isabel Trejo Zambrano, Jody E Hooper, Elissa Leonard, Jamie B Spangler, Andrea L Cox, Carolyn Machamer, Lauren Sauer, Oliver Laeyendecker, Brian T Garibaldi, Stuart C Ray, Christopher A Mecoli, Lisa Christopher-Stine, Laura Gutierrez-Alamillo, Qingyuan Yang, David Hines, William Clarke, Richard Eric Rothman, Andrew S Pekosz, Katherine Fenstermacher, Zitong Wang, Scott L Zeger, Antony Rosen
IgM autoantibodies recognizing ACE2 are associated with severe COVID-19. medRxiv : the preprint server for health sciences (2020)
Jamie B Spangler, Ignacio Moraga, Kevin M Jude, Christina S Savvides, K Christopher Garcia
A strategy for the selection of monovalent antibodies that span protein dimer interfaces. The Journal of biological chemistry 294 (38) (2019)
Jamie B Spangler, Eleonora Trotta, Jakub Tomala, Ariana Peck, Tracy A Young, Christina S Savvides, Stephanie Silveria, Petra Votavova, Joshua Salafsky, Vijay S Pande, Marek Kovar, Jeffrey A Bluestone, K Christopher Garcia
Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy. Journal of immunology (Baltimore, Md. : 1950) 201 (7) (2018)

Jamie B Spangler.css-eqlu8i{font-size:small;padding-left:4px;} (Jamie Spangler)

Publication Activity (10 Years)

Top Topics

Top Venues

Jamie B Spangler (Jamie Spangler)