Jeffery L Smith

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 21

Top Topics

Molecular Docking

Structural Basis

Amyotrophic Lateral Sclerosis

Top Venues

bioRxiv : the preprint server for biology

Pharmaceuticals (Basel, Switzerland)

Molecules (Basel, Switzerland)

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Kesatebrhan Haile Asressu, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, James Wellnitz, Konstantin I Popov, Alison D Axtman, Timothy M Willson
Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity. Pharmaceuticals (Basel, Switzerland) 17 (3) (2024)
Kesatebrhan Haile Asressu, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, James Wellnitz, Konstantin I Popov, Alison D Axtman, Timothy M Willson
Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity. Pharmaceuticals (Basel, Switzerland) 17 (3) (2024)
Kesatebrhan Haile Asressu, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, James Wellnitz, Konstantin I Popov, Alison D Axtman, Timothy M Willson
Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity. Pharmaceuticals (Basel, Switzerland) 17 (3) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J Dickmander, Tammy M Havener, Marcia K Sanders, Jason W Brown, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2. Molecules (Basel, Switzerland) 29 (17) (2024)
Kesatebrhan Haile Asressu, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, James Wellnitz, Konstantin I Popov, Alison D Axtman, Timothy M Willson
Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity. Pharmaceuticals (Basel, Switzerland) 17 (3) (2024)
Xuan Yang, Jeffery L Smith, Michael T Beck, Jennifer M Wilkinson, Ani Michaud, James D Vasta, Matthew B Robers, Timothy M Willson
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells. bioRxiv : the preprint server for biology (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Liang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot S Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. bioRxiv : the preprint server for biology (2023)
Xuan Yang, Jeffery L Smith, Michael T Beck, Jennifer M Wilkinson, Ani Michaud, James D Vasta, Matthew B Robers, Timothy M Willson
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells. bioRxiv : the preprint server for biology (2023)
Frances M Bashore, Ariana B Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S Dunn, Alvaro A Beltran, Jeffery L Smith, David Harold Drewry, Adriana S Beltran, Alison D Axtman
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. Scientific reports 13 (1) (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Xuan Yang, Han Wee Ong, Rebekah J Dickmander, Jeffery L Smith, Jason W Brown, William Tao, Edcon Chang, Nathaniel J Moorman, Alison D Axtman, Timothy M Willson
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2A. bioRxiv : the preprint server for biology (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Xuan Yang, Jeffery L Smith, Michael T Beck, Jennifer M Wilkinson, Ani Michaud, James D Vasta, Matthew B Robers, Timothy M Willson
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells. bioRxiv : the preprint server for biology (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Lang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot Singh Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. eLife 12 (2023)
Kareem A Galal, Andreas Krämer, Benjamin G Strickland, Jeffery L Smith, Rebekah J Dickmander, Nathaniel J Moorman, Timothy M Willson
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3. bioRxiv : the preprint server for biology (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Liang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot S Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. bioRxiv : the preprint server for biology (2023)
Xuan Yang, Jeffery L Smith, Michael T Beck, Jennifer M Wilkinson, Ani Michaud, James D Vasta, Matthew B Robers, Timothy M Willson
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells. Molecules (Basel, Switzerland) 28 (7) (2023)
David Harold Drewry, Frances M Bashore, Armin Bayati, Jeffery L Smith, Rebekah J Dickmander, Stefanie Howell, Sharon Taft-Benz, Sophia M Min, Mohammad Anwar Hossain, Mark Heise, Peter S McPherson, Nathaniel J Moorman, Alison D Axtman
Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses. Journal of medicinal chemistry 65 (19) (2022)