Carrow I Wells (C I Wells, Carrow Wells)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 51

Top Topics

Structure Activity Relationship

Top Venues

ACS chemical neuroscience

bioRxiv : the preprint server for biology

ACS medicinal chemistry letters

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Carrow I Wells, Yi Liang, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Benjamin Eduful, Sean N O'Byrne, Mohammad Anwar Hossain, Carolina Moura Costa Catta-Preta, Priscila Zonzini Ramos, Opher Gileadi, Carina Gileadi, Rafael Miguez Couñago, Brittany Stork, Christopher G Langendorf, Kevin Nay, Jonathan S Oakhill, Debarati Mukherjee, Luigi Racioppi, Anthony R Means, Brian York, Donald P McDonnell, John W Scott, Daniel E Frigo, David Harold Drewry
SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells 12 (2) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Liang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot S Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Carrow I Wells, Yi Liang, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Benjamin Eduful, Sean N O'Byrne, Mohammad Anwar Hossain, Carolina Moura Costa Catta-Preta, Priscila Zonzini Ramos, Opher Gileadi, Carina Gileadi, Rafael Miguez Couñago, Brittany Stork, Christopher G Langendorf, Kevin Nay, Jonathan S Oakhill, Debarati Mukherjee, Luigi Racioppi, Anthony R Means, Brian York, Donald P McDonnell, John W Scott, Daniel E Frigo, David Harold Drewry
SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells 12 (2) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Carrow I Wells, Yi Liang, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Benjamin Eduful, Sean N O'Byrne, Mohammad Anwar Hossain, Carolina Moura Costa Catta-Preta, Priscila Zonzini Ramos, Opher Gileadi, Carina Gileadi, Rafael Miguez Couñago, Brittany Stork, Christopher G Langendorf, Kevin Nay, Jonathan S Oakhill, Debarati Mukherjee, Luigi Racioppi, Anthony R Means, Brian York, Donald P McDonnell, John W Scott, Daniel E Frigo, David Harold Drewry
SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells 12 (2) (2023)
Zachary W Davis-Gilbert, Andreas Krämer, James E Dunford, Stefanie Howell, Filiz Senbabaoglu, Carrow I Wells, Frances M Bashore, Tammy M Havener, Jeffery L Smith, Mohammad Anwar Hossain, Udo Oppermann, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2. ACS medicinal chemistry letters 14 (4) (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Lang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot Singh Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. eLife 12 (2023)
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Liang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navjot S Pabla, Alex N Bullock, Timothy A Benke, Sila K Ultanir, Alison D Axtman
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Maria Florencia Ercoli, Priscila Zonzini Ramos, Rashmi Jain, Joseph Pilotte, Oliver Xiaoou Dong, Ty Thompson, Carrow I Wells, Jonathan M Elkins, Aled M Edwards, Rafael Miguez Couñago, David Harold Drewry, Pamela C Ronald
An open source plant kinase chemogenomics set. Plant direct 6 (11) (2022)
Christopher R M Asquith, Louisa Temme, Michael P East, Tuomo Laitinen, Julie E Pickett, Frank E Kwarcinski, Parvathi Sinha, Carrow I Wells, Gary L Johnson, Reena Zutshi, David Harold Drewry
Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype. ChemMedChem 17 (12) (2022)
Deanna Marie Tiek, Beril Erdogdu, Roham Razaghi, Lu Jin, Norah Sadowski, Carla Alamillo-Ferrer, J Robert Hogg, Bassem R Haddad, David Harold Drewry, Carrow I Wells, Julie E Pickett, Xiao Song, Anshika Goenka, Bo Hu, Samuel A Goldlust, William J Zuercher, Mihaela Pertea, Winston Timp, Shi-Yuan Cheng, Rebecca B Riggins
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas. Science advances 8 (25) (2022)
Xuan Yang, Rebekah J Dickmander, Armin Bayati, Sharon A Taft-Benz, Jeffery L Smith, Carrow I Wells, Emily A Madden, Jason W Brown, Erik M Lenarcic, Boyd L Yount, Edcon Chang, Alison D Axtman, Ralph S Baric, Mark T Heise, Peter S McPherson, Nathaniel J Moorman, Timothy M Willson
Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses. ACS chemical biology 17 (7) (2022)
Anna Cichońska, Balaguru Ravikumar, Robert J Allaway, Fangping Wan, Sungjoon Park, Oleksandr Isaev, Shuya Li, Michael Mason, Andrew Lamb, Ziaurrehman Tanoli, Minji Jeon, Sunkyu Kim, Mariya Popova, Stephen J Capuzzi, Jianyang Zeng, Kristen Dang, Gregory Koytiger, Jaewoo Kang, Carrow I Wells, Timothy M Willson, null null, Tudor I Oprea, Avner Schlessinger, David Harold Drewry, Gustavo Stolovitzky, Krister Wennerberg, Justin Guinney, Tero Aittokallio
Crowdsourced mapping of unexplored target space of kinase inhibitors. Nature communications 12 (1) (2021)
Benjamin J Eduful, Sean N O'Byrne, Louisa Temme, Christopher R M Asquith, Yi Liang, Alfredo Picado, Joseph R Pilotte, Mohammad Anwar Hossain, Carrow I Wells, William J Zuercher, Carolina M C Catta-Preta, Priscila Zonzini Ramos, André de S Santiago, Rafael M Couñago, Christopher G Langendorf, Kévin Nay, Jonathan S Oakhill, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Timothy M Willson, Daniel E Frigo, John W Scott, David Harold Drewry
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes. Journal of medicinal chemistry 64 (15) (2021)
Carrow I Wells, Hassan Al-Ali, David M Andrews, Christopher R M Asquith, Alison D Axtman, Ivan Dikic, Daniel V Ebner, Peter Ettmayer, Christian Fischer, Mathias Frederiksen, Robert E Futrell, Nathanael S Gray, Stephanie B Hatch, Stefan Knapp, Ulrich Lücking, Michael Michaelides, Caitlin E Mills, Susanne Müller, Dafydd Owen, Alfredo Picado, Kumar S Saikatendu, Martin Schröder, Alexandra Stolz, Mariana Tellechea, Brandon J Turunen, Santiago Vilar, Jinhua Wang, William J Zuercher, Timothy M Willson, David Harold Drewry
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. International journal of molecular sciences 22 (2) (2021)
David Harold Drewry, Joel K Annor-Gyamfi, Carrow I Wells, Julie E Pickett, Verena Dederer, Franziska Preuss, Sebastian Mathea, Alison D Axtman
Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration. Journal of medicinal chemistry (2021)
Carrow I Wells, James D Vasta, Cesear R Corona, Jennifer Wilkinson, Chad A Zimprich, Morgan R Ingold, Julie E Pickett, David Harold Drewry, Kathryn M Pugh, Marie K Schwinn, Byounghoon Brian Hwang, Hicham Zegzouti, Kilian V M Huber, Mei Cong, Poncho L Meisenheimer, Timothy M Willson, Matthew B Robers
Quantifying CDK inhibitor selectivity in live cells. Nature communications 11 (1) (2020)
Tigist Y Tamir, David Harold Drewry, Carrow I Wells, Michael B Major, Alison D Axtman
PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor. Scientific reports 10 (1) (2020)
Andrea I Krahn, Carrow I Wells, David Harold Drewry, Lenore K Beitel, Thomas M Durcan, Alison D Axtman
Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases. ACS chemical neuroscience 11 (13) (2020)
Christopher B Wang, Álvaro Lorente-Macías, Carrow I Wells, Julie E Pickett, Alfredo Picado, William J Zuercher, Alison D Axtman
Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series. RSC medicinal chemistry 12 (1) (2020)
Alfredo Picado, Apirat Chaikuad, Carrow I Wells, Safal Shrestha, William J Zuercher, Julie E Pickett, Frank E Kwarcinski, Parvathi Sinha, Chandi S de Silva, Reena Zutshi, Shubin Liu, Natarajan Kannan, Stefan Knapp, David Harold Drewry, Timothy M Willson
A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. Journal of medicinal chemistry 63 (23) (2020)
Christopher R M Asquith, Tuomo Laitinen, Carrow I Wells, Graham J Tizzard, William J Zuercher
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K). Molecules (Basel, Switzerland) 25 (7) (2020)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Carrow I Wells, Jonathan M Elkins, William J Zuercher, Graham J Tizzard, Antti Poso
Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships. ChemMedChem 15 (1) (2019)
Gerson S Profeta, Caio V Dos Reis, André da Silva Santiago, Paulo H C Godoi, Angela M Fala, Carrow I Wells, Roger Sartori, Anita P T Salmazo, Priscila Zonzini Ramos, Katlin B Massirer, Jonathan M Elkins, David Harold Drewry, Opher Gileadi, Rafael M Couñago
Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors. Scientific reports 9 (1) (2019)
Jark Böttcher, David Dilworth, Ulrich Reiser, Ralph A Neumüller, Michael Schleicher, Mark Petronczki, Markus Zeeb, Nikolai Mischerikow, Abdellah Allali-Hassani, Magdalena M Szewczyk, Fengling Li, Steven Kennedy, Masoud Vedadi, Dalia Barsyte-Lovejoy, Peter J Brown, Kilian V M Huber, Catherine M Rogers, Carrow I Wells, Oleg Fedorov, Klaus Rumpel, Andreas Zoephel, Moriz Mayer, Tobias Wunberg, Dietrich Böse, Stephan Zahn, Heribert Arnhof, Helmut Berger, Christoph Reiser, Alexandra Hörmann, Teresa Krammer, Maja Corcokovic, Bernadette Sharps, Sandra Winkler, Daniela Häring, Xiao-Ling Cockcroft, Julian E Fuchs, Barbara Müllauer, Alexander Weiss-Puxbaum, Thomas Gerstberger, Guido Boehmelt, Christopher R Vakoc, Cheryl H Arrowsmith, Mark Pearson, Darryl B McConnell
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nature chemical biology 15 (8) (2019)
Christopher R M Asquith, Kaleb M Naegeli, Michael P East, Tuomo Laitinen, Tammy M Havener, Carrow I Wells, Gary L Johnson, David Harold Drewry, William J Zuercher, David C Morris
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma. Journal of medicinal chemistry 62 (9) (2019)
Daniel M Foulkes, Dominic P Byrne, Wayland Yeung, Safal Shrestha, Fiona P Bailey, Samantha Ferries, Claire E Eyers, Karen Keeshan, Carrow I Wells, David Harold Drewry, William J Zuercher, Natarajan Kannan, Patrick A Eyers
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells. Science signaling 11 (549) (2018)
Dominic P Byrne, Yong Li, Krithika Ramakrishnan, Igor L Barsukov, Edwin Alexander Yates, Claire E Eyers, Dulcé Papy-Garcia, Sandrine Chantepie, Vijayakanth Pagadala, Jian Liu, Carrow I Wells, David Harold Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. The Biochemical journal 475 (15) (2018)
Dominic P Byrne, Yong Li, Pawin Ngamlert, Krithika Ramakrishnan, Claire E Eyers, Carrow I Wells, David Harold Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers
New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. The Biochemical journal 475 (15) (2018)
Carrow I Wells, Nirav R Kapadia, Rafael Miguez Couñago, David Harold Drewry
In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases. MedChemComm 9 (1) (2017)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Paulo H Godoi, Michael P East, Graham J Tizzard, Lee M Graves, Gary L Johnson, Ronna E Dornsife, Carrow I Wells, Jonathan M Elkins, Timothy M Willson, William J Zuercher
Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem 13 (1) (2017)