Han Wee Ong

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 26

Top Topics

Tyrosine Kinase

Anti Inflammatory

Plasmodium Falciparum

Top Venues

ACS chemical neuroscience

Journal of medicinal chemistry

ACS chemical biology

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, Tammy M Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K Sanders, Jacob L Capener, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. Journal of medicinal chemistry 67 (14) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, Tammy M Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K Sanders, Jacob L Capener, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. Journal of medicinal chemistry 67 (14) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J Dickmander, Tammy M Havener, Marcia K Sanders, Jason W Brown, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2. Molecules (Basel, Switzerland) 29 (17) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, Tammy M Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K Sanders, Jacob L Capener, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. Journal of medicinal chemistry 67 (14) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, Tammy M Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K Sanders, Jacob L Capener, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. Journal of medicinal chemistry 67 (14) (2024)
Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, Tammy M Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K Sanders, Jacob L Capener, Rafael Miguez Couñago, Edcon Chang, Andreas Krämer, Nathaniel J Moorman, Mark Heise, Alison D Axtman, David Harold Drewry, Timothy M Willson
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. Journal of medicinal chemistry (2024)
Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher R Mansfield, Michael Chirgwin, Anna Truong, Emily R Derbyshire, Reena Zutshi, David Harold Drewry
Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB. ACS medicinal chemistry letters 14 (12) (2023)
Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher R Mansfield, Michael Chirgwin, Anna Truong, Emily R Derbyshire, Reena Zutshi, David Harold Drewry
Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB. ACS medicinal chemistry letters 14 (12) (2023)
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley, Jacqueline L Norris-Drouin, Stephanie H Cholensky, Christine A Mills, Kenneth H Pearce, Laura E Herring, Dmitri B Kireev, Stephen V Frye, Lindsey I James
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components. ACS chemical biology 18 (3) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Xuan Yang, Han Wee Ong, Rebekah J Dickmander, Jeffery L Smith, Jason W Brown, William Tao, Edcon Chang, Nathaniel J Moorman, Alison D Axtman, Timothy M Willson
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5- a ]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A. ACS omega 8 (42) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Xuan Yang, Han Wee Ong, Rebekah J Dickmander, Jeffery L Smith, Jason W Brown, William Tao, Edcon Chang, Nathaniel J Moorman, Alison D Axtman, Timothy M Willson
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2A. bioRxiv : the preprint server for biology (2023)
Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher R Mansfield, Michael Chirgwin, Anna Truong, Emily R Derbyshire, Reena Zutshi, David Harold Drewry
Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB. ACS medicinal chemistry letters 14 (12) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley, Jacqueline L Norris-Drouin, Stephanie H Cholensky, Christine A Mills, Kenneth H Pearce, Laura E Herring, Dmitri B Kireev, Stephen V Frye, Lindsey I James
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components. ACS chemical biology 18 (3) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley, Jacqueline L Norris-Drouin, Stephanie H Cholensky, Christine A Mills, Kenneth H Pearce, Laura E Herring, Dmitri B Kireev, Stephen V Frye, Lindsey I James
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components. ACS chemical biology 18 (3) (2023)
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley, Jacqueline L Norris-Drouin, Stephanie H Cholensky, Christine A Mills, Kenneth H Pearce, Laura E Herring, Dmitri B Kireev, Stephen V Frye, Lindsey I James
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components. ACS chemical biology (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley, Jacqueline L Norris-Drouin, Stephanie H Cholensky, Christine A Mills, Kenneth H Pearce, Laura E Herring, Dmitri B Kireev, Stephen V Frye, Lindsey I James
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components. ACS chemical biology 18 (3) (2023)
Kareem A Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy M Havener, Michael E Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed A Helal, Emily R Derbyshire, Reena Zutshi, David Harold Drewry
Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial Pf GSK3/ Pf PK6 with Activity against Blood Stage Parasites In Vitro. Journal of medicinal chemistry 65 (19) (2022)