Ka-Fai To (Ka Fai To)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 32

Top Topics

Transforming Growth Factor

Epstein Barr Virus

Histone Deacetylase

Top Venues

Nature communications

Exploration of targeted anti-tumor therapy

Signal transduction and targeted therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying-Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka-Fai To, Albert Wu Cheng, Kwok-Wai Lo
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers. Nature communications 15 (1) (2024)
Bonan Chen, Peiyao Yu, Wai Nok Chan, Fuda Xie, Yigan Zhang, Li Liang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Gary M K Tse, Wei Kang, Ka-Fai To
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets. Signal transduction and targeted therapy 9 (1) (2024)
Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying-Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka-Fai To, Albert Wu Cheng, Kwok-Wai Lo
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers. Nature communications 15 (1) (2024)
Bonan Chen, Peiyao Yu, Wai Nok Chan, Fuda Xie, Yigan Zhang, Li Liang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Gary M K Tse, Wei Kang, Ka-Fai To
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets. Signal transduction and targeted therapy 9 (1) (2024)
Bonan Chen, Peiyao Yu, Wai Nok Chan, Fuda Xie, Yigan Zhang, Li Liang, Kam-Tong Leung, Kwok-Wai Lo, Jun Yu, Gary M K Tse, Wei Kang, Ka-Fai To
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets. Signal transduction and targeted therapy 9 (1) (2024)
Xiaoli Liu, Bonan Chen, Fuda Xie, Kit Yee Wong, Alvin Ho-Kwan Cheung, Jinglin Zhang, Qian Wu, Canbin Fang, Jintao Hu, Shouyu Wang, Dazhi Xu, Jianwu Chen, Yuzhi Wang, Chi Chun Wong, Huarong Chen, William Ka Kei Wu, Jun Yu, Michael Wing-Yan Chan, Chi Man Tsang, Kwok-Wai Lo, Gary M K Tse, Ka-Fai To, Wei Kang
FOXP4 is a Direct YAP1 Target that Promotes Gastric Cancer Stemness and Drives Metastasis. Cancer research (2024)
Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying-Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka-Fai To, Albert Wu Cheng, Kwok-Wai Lo
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers. Nature communications 15 (1) (2024)
Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying-Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka-Fai To, Albert Wu Cheng, Kwok-Wai Lo
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers. Nature communications 15 (1) (2024)
Bei Huang, Steven Wai-Ho Chau, Yaping Liu, Joey Wing Yan Chan, Jing Wang, Suk Ling Ma, Ji-Hui Zhang, Paul Kay Sheung Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent Chung Tong Mok, Ka-Fai To, Hei Ming Lai, Simon Ng, Claudia Trenkwalder, Francis K L Chan, Yun-Kwok Wing
Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. Nature communications 14 (1) (2023)
Bei Huang, Steven Wai-Ho Chau, Yaping Liu, Joey Wing Yan Chan, Jing Wang, Suk Ling Ma, Ji-Hui Zhang, Paul Kay Sheung Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent Chung Tong Mok, Ka-Fai To, Hei Ming Lai, Simon Ng, Claudia Trenkwalder, Francis K L Chan, Yun-Kwok Wing
Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. Nature communications 14 (1) (2023)
Max Kam-Kwan Chan, Emily Lok-Yiu Chan, Zoey Zeyuan Ji, Alex Siu Wing Chan, Chunjie Li, Kam-Tong Leung, Ka-Fai To, Patrick Ming-Kuen Tang
Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy. Exploration of targeted anti-tumor therapy 4 (2) (2023)
Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Vivian Weiwen Xue, Xiao-Ru Huang, Calvin Sze-Hang Ng, Dongmei Zhang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric Wing-Fai Lam, David J Nikolic-Paterson, Ka-Fai To, Hui Yao Lan, Patrick Ming-Kuen Tang
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma. Nature communications 14 (1) (2023)
Bei Huang, Steven Wai-Ho Chau, Yaping Liu, Joey Wing Yan Chan, Jing Wang, Suk Ling Ma, Ji-Hui Zhang, Paul Kay Sheung Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent Chung Tong Mok, Ka-Fai To, Hei Ming Lai, Simon Ng, Claudia Trenkwalder, Francis K L Chan, Yun-Kwok Wing
Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. Nature communications 14 (1) (2023)
Max Kam-Kwan Chan, Emily Lok-Yiu Chan, Zoey Zeyuan Ji, Alex Siu Wing Chan, Chunjie Li, Kam-Tong Leung, Ka-Fai To, Patrick Ming-Kuen Tang
Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy. Exploration of targeted anti-tumor therapy 4 (2) (2023)
Yang Lyu, Fuda Xie, Bonan Chen, Wing Sum Shin, Wei Chen, Yu-Long He, Kam-Tong Leung, Gary M K Tse, Jun Yu, Ka-Fai To, Wei Kang
The nerve cells in gastrointestinal cancers: from molecular mechanisms to clinical intervention. Oncogene (2023)
Bei Huang, Steven Wai-Ho Chau, Yaping Liu, Joey Wing Yan Chan, Jing Wang, Suk Ling Ma, Ji-Hui Zhang, Paul Kay Sheung Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent Chung Tong Mok, Ka-Fai To, Hei Ming Lai, Simon Ng, Claudia Trenkwalder, Francis K L Chan, Yun-Kwok Wing
Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. Nature communications 14 (1) (2023)
Alvin Ho-Kwan Cheung, Kit-Yee Wong, Xiaoli Liu, Fenfen Ji, Chris Ho-Lam Hui, Yihan Zhang, Johnny Sheung-Him Kwan, Bonan Chen, Yujuan Dong, Raymond Wai-Ming Lung, Jun Yu, Kwok-Wai Lo, Chi Chun Wong, Wei Kang, Ka-Fai To
MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5. Oncogenesis 12 (1) (2023)
Max Kam-Kwan Chan, Emily Lok-Yiu Chan, Zoey Zeyuan Ji, Alex Siu Wing Chan, Chunjie Li, Kam-Tong Leung, Ka-Fai To, Patrick Ming-Kuen Tang
Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy. Exploration of targeted anti-tumor therapy 4 (2) (2023)
Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Vivian Weiwen Xue, Xiao-Ru Huang, Calvin Sze-Hang Ng, Dongmei Zhang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric Wing-Fai Lam, David J Nikolic-Paterson, Ka-Fai To, Hui Yao Lan, Patrick Ming-Kuen Tang
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma. Nature communications 14 (1) (2023)
Wenshu Tang, Jingying Zhou, Weiqin Yang, Yu Feng, Haoran Wu, Myth T S Mok, Lingyun Zhang, Zhixian Liang, Xiaoyu Liu, Zhewen Xiong, Xuezhen Zeng, Jing Wang, Jiahuan Lu, Jingqing Li, Hanyong Sun, Xiaoyu Tian, Philip Chun Yeung, Yong Hou, Heung Man Lee, Candice C H Lam, Howard H W Leung, Anthony W H Chan, Ka-Fai To, John Wong, Paul B S Lai, Kelvin Kwok-Chai Ng, Simon K H Wong, Vincent W S Wong, Alice Pik-Shan Kong, Joseph J Y Sung, Alfred S L Cheng
Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver. Cellular & molecular immunology 19 (7) (2022)
Chi Chun Wong, Jian-Lin Wu, Fenfen Ji, Wei Kang, Xiqing Bian, Huarong Chen, Lam-Shing Chan, Simson Tsz Yat Luk, Samuel Tong, Jiaying Xu, Qiming Zhou, Dabin Liu, Hao Su, Hongyan Gou, Alvin Ho-Kwan Cheung, Ka-Fai To, Zongwei Cai, Jerry W Shay, Xin Yu
The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer. Nature communications 13 (1) (2022)
Jeff P Bruce, Ka-Fai To, Vivian Wai Yan Lui, Grace T Y Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y Yip, Brigette Buig Yue Ma, John K S Woo, Edwin Pun Hui, Michael K F Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y Y Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie D Prokopec, Man Wu, Johnny S H Kwan, Yuchen Liu, Jason Ying-Kuen Chan, C Andrew van Hasselt, Lawrence S Young, Christopher W Dawson, Ian Charles Paterson, Lee Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T C Chan, Trevor J Pugh, Kwok-Wai Lo
Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nature communications 13 (1) (2022)
Han Wang, Kathy Yuen Yee Chan, Chi Keung Cheng, Margaret H L Ng, Po Yi Lee, Frankie Wai Tsoi Cheng, Grace Kee See Lam, Tin Wai Chow, Shau-Yin Ha, Alan Kwok Shing Chiang, Wing-Hang Leung, Anskar Yu-Hung Leung, Chi Chiu Wang, Tao Zhang, Xiao-Bing Zhang, Chi Chiu So, Yuet Ping Yuen, Qiwei Sun, Chi Zhang, Yaqun Xu, John Tak Kit Cheung, Wing Hei Ng, Patrick Ming-Kuen Tang, Wei Kang, Ka-Fai To, Wayne Yuk Wai Lee, Raymond Siu Ming Wong, Ellen Ngar Yun Poon, Qi Zhao, Junbin Huang, Chun Chen, Patrick Man Pan Yuen, Chi-Kong Li, Alex Wing Kwan Leung, Kam-Tong Leung
Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine. Blood cancer discovery 3 (6) (2022)
Philip Chiu-Tsun Tang, Jeff Yat-Fai Chung, Jinyue Liao, Max Kam-Kwan Chan, Alex Siu Wing Chan, Guangyao Cheng, Chunjie Li, Xiao-Ru Huang, Calvin Sze-Hang Ng, Eric Wing-Fai Lam, Dongmei Zhang, Yi-Ping Ho, Ka-Fai To, Kam-Tong Leung, Xiaohua Jiang, Ho Ko, Tin-Lap Lee, Hui Yao Lan, Patrick Ming-Kuen Tang
Single-cell RNA sequencing uncovers a neuron-like macrophage subset associated with cancer pain. Science advances 8 (40) (2022)
Liuyang Zhao, Xiang Zhang, Yunfei Zhou, Kaili Fu, Harry Cheuk Hay Lau, Tommy Wai-Yiu Chun, Alvin Ho-Kwan Cheung, Olabisi Oluwabukola Coker, Hong Wei, William Ka-Kei Wu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Ka-Fai To, Jun Yu
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients. Oncogene 41 (36) (2022)
Xi Kang, Weilin Li, Weixin Liu, Han Liang, Jingyu Deng, Chi Chun Wong, Sinan Zhao, Wei Kang, Ka-Fai To, Philip Wai-Yan Chiu, Guiying Wang, Jun Yu, Enders Kwok Wai Ng
LIMK1 promotes peritoneal metastasis of gastric cancer and is a therapeutic target. Oncogene 40 (19) (2021)
Jeff P Bruce, Ka-Fai To, Vivian Wai Yan Lui, Grace T Y Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y Yip, Brigette Buig Yue Ma, John K S Woo, Edwin Pun Hui, Michael K F Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y Y Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie D Prokopec, Man Wu, Johnny S H Kwan, Yuchen Liu, Jason Ying-Kuen Chan, C Andrew van Hasselt, Lawrence S Young, Christopher W Dawson, Ian Charles Paterson, Lee Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T C Chan, Trevor J Pugh, Kwok-Wai Lo
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nature communications 12 (1) (2021)
Weiqin Yang, Yu Feng, Jingying Zhou, Otto Ka-Wing Cheung, Jianquan Cao, Jing Wang, Wenshu Tang, Yalin Tu, Liangliang Xu, Feng Wu, Zhiwu Tan, Hanyong Sun, Yuan Tian, John Wong, Paul Bo San Lai, Stephen Lam Chan, Anthony Wing-Hung Chan, Patrick Boon-Ooi Tan, Zhiwei Chen, Joseph Jao Yiu Sung, Kevin Yuk-Lap Yip, Ka-Fai To, Alfred Sze-Lok Cheng
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma. Science translational medicine 13 (588) (2021)
Wei Kang, Jinglin Zhang, Tingting Huang, Yuhang Zhou, Chi Chun Wong, Ronald C K Chan, Yujuan Dong, Feng Wu, Bin Zhang, William Ka Kei Wu, Michael Wing-Yan Chan, Alfred S L Cheng, Jun Yu, Nathalie Wong, Kwok-Wai Lo, Ka-Fai To
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway. Oncogene 40 (9) (2021)
Matt Lechner, Volker Hans Schartinger, Christopher D Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T Forde, Martin D Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S H Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H Hwang, Quynh-Thu Le, Joshua K Tay, Robert B West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M Willems, Matthew Chin Heng Chua, Pierre Busson, Kwok-Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J Lund
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nature communications 12 (1) (2021)
Kathy Yuen Yee Chan, Chi Zhang, Yorky Tsin Sik Wong, Xiao-Bing Zhang, Chi Chiu Wang, Wing Hei Ng, Siu Ping Fok, Patrick Ming-Kuen Tang, Wei Kang, Bo Feng, Ellen Ngar Yun Poon, King Yiu Lee, Cheuk Kwong Lee, Chun Chen, Tak Yeung Leung, Margaret Heung Ling Ng, Ka-Fai To, Han Wang, Hugh S Hung San Lam, Pak Cheung Ng, Patrick Man Pan Yuen, Karen Li, Alex Wing Kwan Leung, Chi-Kong Li, Kam-Tong Leung
R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling. Blood advances 5 (21) (2021)
Jinglin Zhang, Chi Chun Wong, Kam-Tong Leung, Feng Wu, Yuhang Zhou, Joanna Hung-Man Tong, Ronald C K Chan, Hui Li, Yifei Wang, Huan Yan, Liping Liu, William Ka Kei Wu, Michael Wing-Yan Chan, Alfred S L Cheng, Jun Yu, Nathalie Wong, Kwok-Wai Lo, Ka-Fai To, Wei Kang
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential. Oncogene 39 (43) (2020)