Bart Vanhaesebroeck

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 31

Top Topics

Tyrosine Kinase

Regulatory T Cells

Cognitive Decline

Top Venues

Nature communications

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Albert Herms, Bartomeu Colom, Gabriel Piedrafita, Argyro Kalogeropoulou, Ujjwal Banerjee, Charlotte King, Emilie Abby, Kasumi Murai, Irene Caseda, David Fernandez-Antoran, Swee Hoe Ong, Michael W J Hall, Christopher Bryant, Roshan K Sood, Joanna C Fowler, Albert Pol, Christian Frezza, Bart Vanhaesebroeck, Philip H Jones
Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus. Nature genetics (2024)
Bart Vanhaesebroeck
30 years of PI3K: an interview with Bart Vanhaesebroeck. Future oncology (London, England) (2024)
Sarah E Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Lazaros C Foukas, Mathias Cobbaut, Sandra D Castillo, Mohammad Amin Danesh, Mahreen Adil, Arkaitz Carracedo, Mariona Graupera, Neil Q McDonald, Peter J Parker, Pedro Rodriguez Cutillas, Silvia Surinova, Bart Vanhaesebroeck
A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease. Nature communications 15 (1) (2024)
Sarah E Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Lazaros C Foukas, Mathias Cobbaut, Sandra D Castillo, Mohammad Amin Danesh, Mahreen Adil, Arkaitz Carracedo, Mariona Graupera, Neil Q McDonald, Peter J Parker, Pedro Rodriguez Cutillas, Silvia Surinova, Bart Vanhaesebroeck
A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease. Nature communications 15 (1) (2024)
Bart Vanhaesebroeck
30 years of PI3K: an interview with Bart Vanhaesebroeck. Future oncology (London, England) (2024)
Grace Q Gong, Bart Vanhaesebroeck
Precision Targeting of Mutant PI3Kα. Cancer discovery 14 (2) (2024)
Sarah E Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Lazaros C Foukas, Mathias Cobbaut, Sandra D Castillo, Mohammad Amin Danesh, Mahreen Adil, Arkaitz Carracedo, Mariona Graupera, Neil Q McDonald, Peter J Parker, Pedro Rodriguez Cutillas, Silvia Surinova, Bart Vanhaesebroeck
A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease. Nature communications 15 (1) (2024)
Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei
NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells 12 (2) (2023)
Julian Downward, Peter J Parker, Bart Vanhaesebroeck
Michael D. Waterfield. The Biochemical journal 480 (18) (2023)
Grace Q Gong, Benoit Bilanges, Ben Allsop, Glenn Robert Masson, Victoria H Roberton, Trevor Askwith, Sally Oxenford, Ralitsa R Madsen, Sarah E Conduit, Dom Bellini, Martina Fitzek, Matt Collier, Osman Najam, Zhenhe He, Ben Wahab, Stephen H McLaughlin, A W Edith Chan, Isabella Feierberg, Andrew Madin, Daniele Morelli, Amandeep Bhamra, Vanesa Vinciauskaite, Karen E Anderson, Silvia Surinova, Nikos Pinotsis, Elena Lopez-Guadamillas, Matthew Wilcox, Alice Hooper, Chandni Patel, Maria A Whitehead, Matilda Katan, Len R Stephens, Phillip T Hawkins, Matilda Katan, Derek M Yellon, Sean M Davidson, David M Smith, James B Phillips, Richard Angell, Roger L Williams, Bart Vanhaesebroeck
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature (2023)
Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei
NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells 12 (2) (2023)
Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei
NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells 12 (2) (2023)
Piotr Kobialka, Judith Llena Sopena, Nerea Deleyto-Seldas, Margalida Munar-Gelabert, Jose A Dengra, Pilar Villacampa, Alba Albinyà-Pedrós, Laia Muixi, Jorge Andrade, Hielke van Splunder, Ana Angulo-Urarte, Michael Potente, Joaquím Grego-Bessa, Sandra D Castillo, Bart Vanhaesebroeck, Alejo Efeyan, Mariona Graupera
PI3K-C2β limits mTORC1 signaling and angiogenic growth. Science signaling 16 (813) (2023)
Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei
NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells 12 (2) (2023)
Simon Eschweiler, Ciro Ramírez-Suástegui, Yingcong Li, Emma King, Lindsey Chudley, Jaya Thomas, Oliver Wood, Adrian von Witzleben, Danielle Jeffrey, Katy J McCann, Hayley Simon, Monalisa Mondal, Alice Wang, Martina Dicker, Elena Lopez-Guadamillas, Ting-Fang Chou, Nicola A Dobbs, Louisa Essame, Gary Acton, Fiona Kelly, Gavin Halbert, Joseph J Sacco, Andrew Graeme Schache, Richard J Shaw, James Anthony McCaul, Claire Paterson, Joseph H Davies, Peter A Brennan, Rabindra P Singh, Paul M Loadman, William Wilson, Allan Hackshaw, Grégory Seumois, Klaus Okkenhaug, Gareth J Thomas, Terry M Jones, Ferhat Ay, Greg Friberg, Mitchell Kronenberg, Bart Vanhaesebroeck, Pandurangan Vijayanand, Christian Hermann Ottensmeier
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. Nature 605 (7911) (2022)
Priyanka Tibarewal, Victoria Rathbone, Georgia Constantinou, Wayne Pearce, Mahreen Adil, Zofia Varyova, Lisa Folkes, Alix Hampson, Gala Anastasia Electra Classen, Adriana Alves, Sara Carvalho, Cheryl L Scudamore, Bart Vanhaesebroeck
Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development. The Journal of pathology 258 (4) (2022)
Sarah Nicol Lauder, Kathryn Smart, Valentina M T Bart, Ana Pires, Jake Scott, Stefan Milutinovic, Andrew Godkin, Bart Vanhaesebroeck, Awen Gallimore
Treg-driven tumour control by PI3Kδ inhibition limits myeloid-derived suppressor cell expansion. British journal of cancer 127 (9) (2022)
Valentí Gómez, Myria Galazi, Gregory Weitsman, James Monypenny, Fahad Al-Salemee, Paul R Barber, Kenrick Ng, Richard Beatson, Bálint Szokol, László Őrfi, Greg Mullen, Bart Vanhaesebroeck, Simon Chowdhury, Hing Y Leung, Tony Ng
HER2 Mediates PSMA/mGluR1-Driven Resistance to the DS-7423 Dual PI3K/mTOR Inhibitor in PTEN Wild-type Prostate Cancer Models. Molecular cancer therapeutics 21 (4) (2022)
Bart Vanhaesebroeck, John E Burke, Ralitsa R Madsen
Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation. Cancer discovery 12 (1) (2022)
Typhaine Anquetil, Romain Solinhac, Aude Jaffre, Gaëtan Chicanne, Julien Viaud, Jean Darcourt, Cyrille Orset, Eva Geuss, Christoph Kleinschnitz, Bart Vanhaesebroeck, Denis Vivien, Karim Hnia, Vincent Larrue, Bernard Payrastre, Marie-Pierre Gratacap
PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity. EMBO reports 22 (6) (2021)
Ralitsa R Madsen, Emily C Erickson, Oscar M Rueda, Xavier Robin, Carlos Caldas, Alex Toker, Robert K Semple, Bart Vanhaesebroeck
Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype. PLoS genetics 17 (11) (2021)
Bart Vanhaesebroeck, Matthew W D Perry, Jennifer R Brown, Fabrice Andre, Klaus Okkenhaug
PI3K inhibitors are finally coming of age. Nature reviews. Drug discovery 20 (10) (2021)
Oscar Emanuel, Jacklyn Liu, Volker Hans Schartinger, Wen Long Nei, Yuk Yu Chan, Chi Man Tsang, Herbert Riechelmann, Liam Masterson, Johannes Haybaeck, Udo Oppermann, Stefan M Willems, Marc L Ooft, Guido Wollmann, David Howard, Bart Vanhaesebroeck, Valerie J Lund, Gary Royle, Matthew Chin Heng Chua, Kwok-Wai Lo, Pierre Busson, Matt Lechner
SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target. Cancers 13 (19) (2021)
Matt Lechner, Volker Hans Schartinger, Christopher D Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T Forde, Martin D Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S H Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H Hwang, Quynh-Thu Le, Joshua K Tay, Robert B West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M Willems, Matthew Chin Heng Chua, Pierre Busson, Kwok-Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J Lund
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nature communications 12 (1) (2021)
Pavel Zhabyeyev, Xueyi Chen, Bart Vanhaesebroeck, Gavin Y Oudit
PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias. Channels (Austin, Tex.) 13 (1) (2020)
Ralitsa R Madsen, Bart Vanhaesebroeck
Cracking the context-specific PI3K signaling code. Science signaling 13 (613) (2020)
Anne-Katrien Stark, Elizabeth C M Davenport, Daniel T Patton, Cheryl L Scudamore, Bart Vanhaesebroeck, Marc Veldhoen, Oliver A Garden, Klaus Okkenhaug
Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation. Journal of immunology (Baltimore, Md. : 1950) 205 (1) (2020)
Benoit Bilanges, York Posor, Bart Vanhaesebroeck
PI3K isoforms in cell signalling and vesicle trafficking. Nature reviews. Molecular cell biology 20 (9) (2020)
Abul K Azad, Pavel Zhabyeyev, Bart Vanhaesebroeck, Gary Eitzen, Gavin Y Oudit, Ronald B Moore, Allan G Murray
Inactivation of endothelial cell phosphoinositide 3-kinase β inhibits tumor angiogenesis and tumor growth. Oncogene 39 (41) (2020)
Ralitsa R Madsen, Rachel G Knox, Wayne Pearce, Saioa Lopez, Betania Mahler-Araujo, Nicholas McGranahan, Bart Vanhaesebroeck, Robert K Semple
Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner. Proceedings of the National Academy of Sciences of the United States of America 116 (17) (2019)
Ramon Martinez-Marmol, Nika Mohannak, Lei Qian, Tong Wang, Rachel S Gormal, Marc J Ruitenberg, Bart Vanhaesebroeck, Elizabeth J Coulson, Frédéric A Meunier
p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (40) (2019)