Ke Lan

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 50

Top Venues

Wuhan University State Key laboratory of Virology

Central South University Xiangya School of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Wuhan University State Key laboratory of Virology Jan 01 2017

China

Director/Professor :: State Key Laboratory of Virology

Institut Pasteur of Shanghai Chinese Academy of Sciences Aug 01 2006 - Dec 31 2016

China

Principal Investigator/Professor :: Tumor Virology

University of Pennsylvania Perelman School of Medicine Jun 15 2002 - Dec 31 2007

United States

Postdoctoral Fellow/Research Associate :: Microbiology

People's Hospital of Pingshan Aug 01 1994 - Aug 01 1995

China

Residency :: Internal Medicine

Education History

Central South University Xiangya School of Medicine Sep 01 1998 - Jul 01 2001

China

PHD :: Cancer Research Institute

Chongqing Medical University Sep 01 1995 - Jul 01 1998

China

MSC :: Pathophysiology

Chongqing Medical University Sep 01 1989 - Jul 01 1994

China

BSC :: Clinincal Medicine

Publications

Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Hongyun Wang, Jiangpeng Feng, Zhiying Fu, Tianmo Xu, Jiejie Liu, Shimin Yang, Yingjian Li, Jikai Deng, Yuzhen Zhang, Ming Guo, Xin Wang, Zhen Zhang, Zhixiang Huang, Ke Lan, Li Zhou, Yu Chen
Epitranscriptomic m 5 C methylation of SARS-CoV-2 RNA regulates viral replication and the virulence of progeny viruses in the new infection. Science advances 10 (32) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology (2024)
Chunyan Han, Chenwu Gui, Shuhong Dong, Ke Lan
The Interplay between KSHV Infection and DNA-Sensing Pathways. Viruses 16 (5) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Xian Li, Mengxin Xu, Jingyi Yang, Li Zhou, Lin Liu, Min Li, Shasha Wang, Mei-Qin Liu, Zhixiang Huang, Zhen Zhang, Shuning Liu, Yunqi Hu, Haofeng Lin, Bowen Liu, Ying Sun, Qingguo Wu, Zheng-Li Shi, Ke Lan, Yu Chen, Huimin Yan, Yao-Qing Chen
Nasal vaccination of triple-RBD scaffold protein with flagellin elicits long-term protection against SARS-CoV-2 variants including JN.1. Signal transduction and targeted therapy 9 (1) (2024)
Danping Niu, Yuanming Ma, Pengyu Ren, Sijia Chang, Chenhui Li, Yong Jiang, Chunyan Han, Ke Lan
Methylation of KSHV vCyclin by PRMT5 contributes to cell cycle progression and cell proliferation. PLoS pathogens 20 (9) (2024)
Hongyun Wang, Jiangpeng Feng, Zhiying Fu, Tianmo Xu, Jiejie Liu, Shimin Yang, Yingjian Li, Jikai Deng, Yuzhen Zhang, Ming Guo, Xin Wang, Zhen Zhang, Zhixiang Huang, Ke Lan, Li Zhou, Yu Chen
Epitranscriptomic m 5 C methylation of SARS-CoV-2 RNA regulates viral replication and the virulence of progeny viruses in the new infection. Science advances 10 (32) (2024)
Chunyan Han, Chenwu Gui, Shuhong Dong, Ke Lan
The Interplay between KSHV Infection and DNA-Sensing Pathways. Viruses 16 (5) (2024)
Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou, Yanbin Guan, Shiying Fu, Youyou Lin, Huan Yan, Zhen Zhang, Xiang Li, Xiu-Na Yang, Haitao Yang, Hangtian Guo, Ke Lan, Yu Chen, Shin-Chen Hou, Yi Xiong
A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug. Cell death & disease 15 (6) (2024)
Chunyan Han, Chenwu Gui, Shuhong Dong, Ke Lan
The Interplay between KSHV Infection and DNA-Sensing Pathways. Viruses 16 (5) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Pengyu Ren, Danping Niu, Sijia Chang, Lei Yu, Junrui Ren, Yuanming Ma, Ke Lan
RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. Journal of virology 98 (2) (2024)
Xian Li, Mengxin Xu, Jingyi Yang, Li Zhou, Lin Liu, Min Li, Shasha Wang, Mei-Qin Liu, Zhixiang Huang, Zhen Zhang, Shuning Liu, Yunqi Hu, Haofeng Lin, Bowen Liu, Ying Sun, Qingguo Wu, Zheng-Li Shi, Ke Lan, Yu Chen, Huimin Yan, Yao-Qing Chen
Nasal vaccination of triple-RBD scaffold protein with flagellin elicits long-term protection against SARS-CoV-2 variants including JN.1. Signal transduction and targeted therapy 9 (1) (2024)
Yongliang Zhao, Wenjia Ni, Simeng Liang, Lianghui Dong, Min Xiang, Zeng Cai, Danping Niu, Qiuhan Zhang, Dehe Wang, Yucheng Zheng, Zhen Zhang, Dan Zhou, Wenhua Guo, Yongbing Pan, Xiaoli Wu, Yimin Yang, Zhaofei Jing, Yongzhong Jiang, Yu Chen, Huan Yan, Yu Zhou, Ke Xu, Ke Lan
Vaccination with S pan , an antigen guided by SARS-CoV-2 S protein evolution, protects against challenge with viral variants in mice. Science translational medicine 15 (677) (2023)
Qianyun Liu, Haiyan Zhao, Zhiqiang Li, Zhen Zhang, Rui Huang, Mengxue Gu, Ke Zhuang, Qing Xiong, Xianying Chen, Weiyi Yu, Shengnan Qian, Yuzhen Zhang, Xue Tan, Muyi Zhang, Feiyang Yu, Ming Guo, Zhixiang Huang, Xin Wang, Wenjie Xiang, Bihao Wu, Fanghua Mei, Kun Cai, Limin Zhou, Li Zhou, Ying Wu, Huan Yan, Sheng Cao, Ke Lan, Yu Chen
Broadly neutralizing antibodies derived from the earliest COVID-19 convalescents protect mice from SARS-CoV-2 variants challenge. Signal transduction and targeted therapy 8 (1) (2023)
Yongliang Zhao, Wenjia Ni, Simeng Liang, Lianghui Dong, Min Xiang, Zeng Cai, Danping Niu, Qiuhan Zhang, Dehe Wang, Yucheng Zheng, Zhen Zhang, Dan Zhou, Wenhua Guo, Yongbing Pan, Xiaoli Wu, Yimin Yang, Zhaofei Jing, Yongzhong Jiang, Yu Chen, Huan Yan, Yu Zhou, Ke Xu, Ke Lan
Vaccination with S pan , an antigen guided by SARS-CoV-2 S protein evolution, protects against challenge with viral variants in mice. Science translational medicine 15 (677) (2023)
Hui Fan, Li Zhou, Jingjun Lv, Shimin Yang, Guozhong Chen, Xinjin Liu, Chunyan Han, Xue Tan, Shengnan Qian, Zegang Wu, Shan Yu, Ming Guo, Chengliang Zhu, Yu Chen, Ke Lan
Bacterial coinfections contribute to severe COVID-19 in winter. Cell research (2023)
Liangxia Ai, Yafei Li, Li Zhou, Wenrong Yao, Hao Zhang, Zhaoyu Hu, Jinyu Han, Weijie Wang, Junmiao Wu, Pan Xu, Ruiyue Wang, Zhangyi Li, Zhouwang Li, Chengliang Wei, Jianqun Liang, Haobo Chen, Zhimiao Yang, Ming Guo, Zhixiang Huang, Xin Wang, Zhen Zhang, Wenjie Xiang, Dazheng Sun, Lianqiang Xu, Meiyan Huang, Bin Lv, Peiqi Peng, Shangfeng Zhang, Xuhao Ji, Huiyi Luo, Nanping Chen, Jianping Chen, Ke Lan, Yong Hu
Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2. Cell discovery 9 (1) (2023)
Liangxia Ai, Yafei Li, Li Zhou, Wenrong Yao, Hao Zhang, Zhaoyu Hu, Jinyu Han, Weijie Wang, Junmiao Wu, Pan Xu, Ruiyue Wang, Zhangyi Li, Zhouwang Li, Chengliang Wei, Jianqun Liang, Haobo Chen, Zhimiao Yang, Ming Guo, Zhixiang Huang, Xin Wang, Zhen Zhang, Wenjie Xiang, Dazheng Sun, Lianqiang Xu, Meiyan Huang, Bin Lv, Peiqi Peng, Shangfeng Zhang, Xuhao Ji, Huiyi Luo, Nanping Chen, Jianping Chen, Ke Lan, Yong Hu
Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2. Cell discovery 9 (1) (2023)
Fabin Dang, Lei Bai, Jiazhen Dong, Xiaoping Hu, Jingchao Wang, Joao A Paulo, Yan Xiong, Xiaowei Liang, Yishuang Sun, Yuncai Chen, Ming Guo, Xin Wang, Zhixiang Huang, Hiroyuki Inuzuka, Li Chen, Chen Chu, Jianping Liu, Tao Zhang, Abdol-Hossein Rezaeian, Jing Liu, Husnu Ümit Kaniskan, Bo Zhong, Jinfang Zhang, Michael Letko, Jian Jin, Ke Lan, Wenyi Wei
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice. Science translational medicine 15 (725) (2023)
Xuezhang Tian, Yaru Zhou, Shaowei Wang, Ming Gao, Yanlin Xia, Yangyang Li, Yunhong Zhong, Wenhao Xu, Lei Bai, Bishi Fu, Yu Zhou, Hye-Ra Lee, Hongyu Deng, Ke Lan, Pinghui Feng, Junjie Zhang
Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses. mBio (2023)
Yongliang Zhao, Wenjia Ni, Simeng Liang, Lianghui Dong, Min Xiang, Zeng Cai, Danping Niu, Qiuhan Zhang, Dehe Wang, Yucheng Zheng, Zhen Zhang, Dan Zhou, Wenhua Guo, Yongbing Pan, Xiaoli Wu, Yimin Yang, Zhaofei Jing, Yongzhong Jiang, Yu Chen, Huan Yan, Yu Zhou, Ke Xu, Ke Lan
Vaccination with S pan , an antigen guided by SARS-CoV-2 S protein evolution, protects against challenge with viral variants in mice. Science translational medicine 15 (677) (2023)
Liangxia Ai, Yafei Li, Li Zhou, Wenrong Yao, Hao Zhang, Zhaoyu Hu, Jinyu Han, Weijie Wang, Junmiao Wu, Pan Xu, Ruiyue Wang, Zhangyi Li, Zhouwang Li, Chengliang Wei, Jianqun Liang, Haobo Chen, Zhimiao Yang, Ming Guo, Zhixiang Huang, Xin Wang, Zhen Zhang, Wenjie Xiang, Dazheng Sun, Lianqiang Xu, Meiyan Huang, Bin Lv, Peiqi Peng, Shangfeng Zhang, Xuhao Ji, Huiyi Luo, Nanping Chen, Jianping Chen, Ke Lan, Yong Hu
Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2. Cell discovery 9 (1) (2023)
Chunyan Han, Dun Zhang, Chenwu Gui, Liang Huang, Sijia Chang, Lianghui Dong, Lei Bai, Shuwen Wu, Ke Lan
KSHV RTA antagonizes SMC5/6 complex-induced viral chromatin compaction by hijacking the ubiquitin-proteasome system. PLoS pathogens 18 (8) (2022)
Chengbao Ma, Xianying Chen, Fanghua Mei, Qing Xiong, Qianyun Liu, Lianghui Dong, Chen Liu, Wenjing Zou, Faxian Zhan, Bing Hu, Yingle Liu, Fang Liu, Li Zhou, Junqiang Xu, Yongzhong Jiang, Ke Xu, Kun Cai, Yu Chen, Huan Yan, Ke Lan
Drastic decline in sera neutralization against SARS-CoV-2 Omicron variant in Wuhan COVID-19 convalescents. Emerging microbes & infections 11 (1) (2022)
Qing Xiong, Lei Cao, Chengbao Ma, M Alejandra Tortorici, Chen Liu, Junyu Si, Peng Liu, Mengxue Gu, Alexandra C Walls, Chunli Wang, Lulu Shi, Fei Tong, Meiling Huang, Jing Li, Chufeng Zhao, Chao Shen, Yu Chen, Huabin Zhao, Ke Lan, Davide Corti, David J Veesler, Xiangxi Wang, Huan Yan
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors. Nature (2022)
Shan Su, Duo Hua, Jin-Peng Li, Xia-Nan Zhang, Lei Bai, Li-Bo Cao, Yi Guo, Ming Zhang, Jia-Zhen Dong, Xiao-Wei Liang, Ke Lan, Ming-Ming Hu, Hong-Bing Shu
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone. Signal transduction and targeted therapy 7 (1) (2022)
Lei Bai, Yongliang Zhao, Jiazhen Dong, Simeng Liang, Ming Guo, Xinjin Liu, Xin Wang, Zhixiang Huang, Xiaoyi Sun, Zhen Zhang, Lianghui Dong, Qianyun Liu, Yucheng Zheng, Danping Niu, Min Xiang, Kun Song, Jiajie Ye, Wenchao Zheng, Zhidong Tang, Mingliang Tang, Yu Zhou, Chao Shen, Ming Dai, Li Zhou, Yu Chen, Huan Yan, Ke Lan, Ke Xu
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity. Cell research 31 (4) (2021)
Yunhua Liu, Rui Sun, Xianzhi Lin, Deguang Liang, Qiang Deng, Ke Lan
Correction for Liu et al., "Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5". Journal of virology 95 (4) (2021)
Zhen Zhang, Qianyun Liu, Ying Sun, Jiali Li, Jiejie Liu, Ruangang Pan, Liu Cao, Xianying Chen, Yingjian Li, Yuzhen Zhang, Ke Xu, Deyin Guo, Li Zhou, Ke Lan, Yu Chen
Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice. Emerging microbes & infections 10 (1) (2021)
Huan Yan, Hengwu Jiao, Qianyun Liu, Zhen Zhang, Qing Xiong, Bing-Jun Wang, Xin Wang, Ming Guo, Lin-Fa Wang, Ke Lan, Yu Chen, Huabin Zhao
ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species. Nature ecology & evolution 5 (5) (2021)
Lianghui Dong, Jiazhen Dong, Min Xiang, Ping Lei, Zixian Li, Fang Zhang, Xiaoyi Sun, Danping Niu, Lei Bai, Ke Lan
NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase. PLoS pathogens 17 (6) (2021)
Qiuhan Zhang, Siliang Li, Ping Lei, Zixian Li, Feifei Chen, Qi Chen, Yulu Wang, Jiami Gong, Qi Tang, Xinjin Liu, Ke Lan, Shuwen Wu
ANXA2 Facilitates Enterovirus 71 Infection by Interacting with 3D Polymerase and PI4KB to Assist the Assembly of Replication Organelles. Virologica Sinica (2021)
Yuan Liu, Zhi Ning, Yu Chen, Ming Guo, Yingle Liu, Nirmal Kumar Gali, Li Sun, Yusen Duan, Jing Cai, Dane Westerdahl, Xinjin Liu, Ke Xu, Kin Fai Ho, Haidong Kan, Qingyan Fu, Ke Lan
Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals. Nature 582 (7813) (2020)
Ke Hu, Mengmei Wang, Yang Zhao, Yunting Zhang, Tao Wang, Zhishui Zheng, Xiaochen Li, Shaolin Zeng, Dong Zhao, HongLin Li, Ke Xu, Ke Lan
A Small-Scale Medication of Leflunomide as a Treatment of COVID-19 in an Open-Label Blank-Controlled Clinical Trial. Virologica Sinica 35 (6) (2020)
Rong Zhang, Xiaohua Chen, Yuqing Huang, Qi Zhang, Yan Cheng, Nan Zhang, Haibo Zhang, Bo Yang, Fang Liu, Yingle Liu, Ke Lan
A Study of Two Cases Co-Infected with SARS-CoV-2 and Human Immunodeficiency Virus. Virologica Sinica 35 (6) (2020)
Xiaoqin Wei, Jiazhen Dong, Chin-Chen Cheng, Mingjun Ji, Lei Yu, Shengqiu Luo, Shuwen Wu, Lei Bai, Ke Lan
Host RAB11FIP5 protein inhibits the release of Kaposi's sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45. PLoS pathogens 16 (12) (2020)
Lijun Yan, Vladimir Majerciak, Zhi-Ming Zheng, Ke Lan
Towards Better Understanding of KSHV Life Cycle: from Transcription and Posttranscriptional Regulations to Pathogenesis. Virologica Sinica 34 (2) (2019)
Junhua Li, Jun Zhao, Simin Xu, Shu Zhang, Junjie Zhang, Jun Xiao, Ruoyun Gao, Mao Tian, Yi Zeng, Katie Lee, Vera Tarakanova, Ke Lan, Hao Feng, Pinghui Feng
Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import. Science advances 5 (10) (2019)
Lei Bai, Jiazhen Dong, Zhenqiu Liu, Youliang Rao, Pinghui Feng, Ke Lan
Viperin catalyzes methionine oxidation to promote protein expression and function of helicases. Science advances 5 (8) (2019)
Fang Zhang, Deguang Liang, Xiaoxi Lin, Zhe Zou, Rui Sun, Xing Wang, Xiaozhen Liang, Kenneth M Kaye, Ke Lan
NDRG1 facilitates the replication and persistence of Kaposi's sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA. PLoS pathogens 15 (2) (2019)
Xiaoqin Wei, Lei Bai, Lianghui Dong, Huimei Liu, Peidong Xing, Zhiyao Zhou, Shuwen Wu, Ke Lan
NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA. PLoS pathogens 15 (11) (2019)
Ke Lan, Min-Hua Luo
Herpesviruses: epidemiology, pathogenesis, and interventions. Virologica Sinica 32 (5) (2018)
Fei Yuan, Zeng-Qiang Gao, Vladimir Majerciak, Lei Bai, Meng-Lu Hu, Xiao-Xi Lin, Zhi-Ming Zheng, Yu-Hui Dong, Ke Lan
The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function. PLoS pathogens 14 (8) (2018)
Xing Wang, Zhe Zou, Zhaohui Deng, Deguang Liang, Xin Zhou, Rui Sun, Ke Lan
Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma. PLoS pathogens 13 (9) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ke Lan