Kevin M Rattigan (Kevin Rattigan)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 12

Top Topics

Oxidative Stress

Endoplasmic Reticulum

Chronic Myeloid Leukemia

Top Venues

Nature communications

Science translational medicine

PLoS neglected tropical diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Martha M Zarou, Kevin M Rattigan, Daniele Sarnello, Engy Shokry, Amy Dawson, Angela Ianniciello, Karen M Dunn, Mhairi Copland, David Sumpton, Alexei Vazquez, G Vignir Helgason
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing. Nature communications 15 (1) (2024)
Martha M Zarou, Kevin M Rattigan, Daniele Sarnello, Engy Shokry, Amy Dawson, Angela Ianniciello, Karen M Dunn, Mhairi Copland, David Sumpton, Alexei Vazquez, G Vignir Helgason
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing. Nature communications 15 (1) (2024)
Ahmed Khalaf, Lucie de Beauchamp, Eric R Kalkman, Kevin M Rattigan, Ekaterini Himonas, Joe Jones, Daniel James, Engy Shokry Abd Shokry, Mary T Scott, Karen M Dunn, Saverio Tardito, Mhairi Copland, David Sumpton, Emma Shanks, G Vignir Helgason
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science translational medicine 16 (751) (2024)
Ahmed Khalaf, Lucie de Beauchamp, Eric R Kalkman, Kevin M Rattigan, Ekaterini Himonas, Joe Jones, Daniel James, Engy Shokry Abd Shokry, Mary T Scott, Karen M Dunn, Saverio Tardito, Mhairi Copland, David Sumpton, Emma Shanks, G Vignir Helgason
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science translational medicine 16 (751) (2024)
Martha M Zarou, Kevin M Rattigan, Daniele Sarnello, Engy Shokry, Amy Dawson, Angela Ianniciello, Karen M Dunn, Mhairi Copland, David Sumpton, Alexei Vazquez, G Vignir Helgason
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing. Nature communications 15 (1) (2024)
Martha M Zarou, Kevin M Rattigan, Daniele Sarnello, Engy Shokry, Amy Dawson, Angela Ianniciello, Karen M Dunn, Mhairi Copland, David Sumpton, Alexei Vazquez, G Vignir Helgason
Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing. Nature communications 15 (1) (2024)
Kevin M Rattigan, Martha M Zarou, G Vignir Helgason
Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood (2023)
Kevin M Rattigan, Martha M Zarou, Zuzana Brabcova, Bodhayan Prasad, Désirée Zerbst, Daniele Sarnello, Eric R Kalkman, Angela Ianniciello, Mary T Scott, Karen Dunn, Engy Shokry, David Sumpton, Mhairi Copland, Saverio Tardito, Johan Vande Voorde, Francis Jay Mussai, Paul Cheng, G Vignir Helgason
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO reports (2023)
Kevin M Rattigan, Martha M Zarou, G Vignir Helgason
Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood (2023)
Angela Ianniciello, Martha M Zarou, Kevin M Rattigan, Mary T Scott, Amy Dawson, Karen M Dunn, Zuzana Brabcova, Eric R Kalkman, Colin Nixon, Alison M Michie, Mhairi Copland, David Vetrie, Martin Ambler, Barbara Saxty, G Vignir Helgason
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science translational medicine 13 (613) (2021)
Kevin M Rattigan, Andrew W Pountain, Clement Regnault, Fiona Achcar, Isabel M Vincent, Carl S Goodyear, Michael P Barrett
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli. PloS one 13 (3) (2018)
Pieter C Steketee, Isabel M Vincent, Fiona Achcar, Federica Giordani, Dong-Hyun Kim, Darren John Creek, Yvonne Freund, Robert Jacobs, Kevin M Rattigan, David Horn, Mark C Field, Annette MacLeod, Michael P Barrett
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei. PLoS neglected tropical diseases 12 (5) (2018)