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Laurent Roberto Chiarelli (Laurent Robert Chiarelli, Laurent R Chiarelli)

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 33

Top Venues

International journal of molecular sciences

Pharmaceuticals (Basel, Switzerland)

Pharmaceutics

ACS infectious diseases

Università degli Studi di Pavia

University of Pavia (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Università degli Studi di Pavia Nov 16o 2019

Italy

Associate Professor :: Department of Biology and Biotechnology

Education History

University of Pavia Nov 1o 2001 - Apr 1o 2004

Italy

PHD :: Department of Biochemistry

Publications

Deborah Recchia, Giovanni Stelitano, Alessandro Stamilla, Damaris L Gutierrez, Giulia Degiacomi, Laurent Roberto Chiarelli, Maria Rosalia Pasca
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options. International journal of molecular sciences 24 (5) (2023)
Dongguang Fan, Bin Wang, Giovanni Stelitano, Karin Savková, Olga Riabova, Rui Shi, Xiaomei Wu, Laurent Roberto Chiarelli, Katarína Mikušová, Vadim A Makarov, Yu Lu, Yuzhi Hong, Chunhua Qiao
Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity. Biomedicines 11 (7) (2023)
Giulia Degiacomi, Beatrice Gianibbi, Deborah Recchia, Giovanni Stelitano, Giuseppina Ivana Truglio, Paola Marra, Alessandro Stamilla, Vadim A Makarov, Laurent Roberto Chiarelli, Fabrizio Manetti, Maria Rosalia Pasca
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis . ACS omega 8 (28) (2023)
Maura D'Amato, Monica Campagnoli, Paolo Iadarola, Paola Margherita Bignami, Marco Fumagalli, Laurent Roberto Chiarelli, Giovanni Stelitano, Federica Meloni, Pasquale Linciano, Simona Collina, Giampiero Pietrocola, Valentina Vertui, Anna Aliberti, Tommaso Fossali, Simona Viglio
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? International journal of molecular sciences 24 (17) (2023)
Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent Roberto Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe Felice Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Targeting Siderophore-Mediated Iron Uptake in M. abscessus : A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria. Pharmaceutics 15 (2) (2023)
Deborah Recchia, Giovanni Stelitano, Alessandro Stamilla, Damaris L Gutierrez, Giulia Degiacomi, Laurent Roberto Chiarelli, Maria Rosalia Pasca
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options. International journal of molecular sciences 24 (5) (2023)
Giovanni Stelitano, Mario Cocorullo, Matteo Mori, Stefania Villa, Fiorella Meneghetti, Laurent Roberto Chiarelli
Iron Acquisition and Metabolism as a Promising Target for Antimicrobials (Bottlenecks and Opportunities): Where Do We Stand? International journal of molecular sciences 24 (7) (2023)
Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent Roberto Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe Felice Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Targeting Siderophore-Mediated Iron Uptake in M. abscessus : A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria. Pharmaceutics 15 (2) (2023)
Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent Roberto Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe Felice Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Targeting Siderophore-Mediated Iron Uptake in M. abscessus : A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria. Pharmaceutics 15 (2) (2023)
Mario Cocorullo, Laurent Roberto Chiarelli, Giovanni Stelitano
Improving Protection to Prevent Bacterial Infections: Preliminary Applications of Reverse Vaccinology against the Main Cystic Fibrosis Pathogens. Vaccines 11 (7) (2023)
Deborah Recchia, Giovanni Stelitano, Alessandro Stamilla, Damaris L Gutierrez, Giulia Degiacomi, Laurent Roberto Chiarelli, Maria Rosalia Pasca
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options. International journal of molecular sciences 24 (5) (2023)
Matteo Mori, Stefania Villa, Laurent Roberto Chiarelli, Fiorella Meneghetti, Marco Bellinzoni
Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery. Pharmaceuticals (Basel, Switzerland) 16 (11) (2023)
José Manuel Ezquerra-Aznárez, Giulia Degiacomi, Henrich Gašparovič, Giovanni Stelitano, Jose Camilla Sammartino, Jana Korduláková, Paolo Governa, Fabrizio Manetti, Maria Rosalia Pasca, Laurent Roberto Chiarelli, Santiago Ramón-García
The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme. International journal of molecular sciences 23 (2) (2022)
Giulia Degiacomi, Vadim A Makarov, Maria Rosalia Pasca, Laurent Roberto Chiarelli
New Drugs and Novel Cellular Targets against Tuberculosis. International journal of molecular sciences 23 (22) (2022)
Rui Shi, Bin Wang, Giovanni Stelitano, Xiaomei Wu, Yuanyuan Shan, Yue Wu, Xin Wang, Laurent Roberto Chiarelli, Yu Lu, Chunhua Qiao
Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents. ACS medicinal chemistry letters 13 (4) (2022)
Matteo Mori, Giovanni Stelitano, Anna Griego, Laurent Roberto Chiarelli, Giulia Cazzaniga, Arianna Gelain, Elena Pini, Marina Camera, Paola Canzano, Andrea Fumagalli, Edoardo Scarpa, Chiara Cordiglieri, Loris Rizzello, Stefania Villa, Fiorella Meneghetti
Synthesis and Assessment of the In Vitro and Ex Vivo Activity of Salicylate Synthase (Mbti) Inhibitors as New Candidates for the Treatment of Mycobacterial Infections. Pharmaceuticals (Basel, Switzerland) 15 (8) (2022)
Elena G Salina, Umberto Postiglione, Laurent Roberto Chiarelli, Deborah Recchia, Monika Záhorszká, Alexander Lepioshkin, Natalia Monakhova, Adrian Pál, Alessio Porta, Giuseppe Zanoni, Jana Korduláková, Elena Kazakova, Davide Sassera, Maria Rosalia Pasca, Vadim A Makarov, Giulia Degiacomi
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro , In Vivo , and against Nonreplicating Cells of Mycobacterium tuberculosis. mSphere (2022)
Matteo Mori, Giovanni Stelitano, Laurent Roberto Chiarelli, Giulia Cazzaniga, Arianna Gelain, Daniela Barlocco, Elena Pini, Fiorella Meneghetti, Stefania Villa
Synthesis, Characterization, and Biological Evaluation of New Derivatives Targeting MbtI as Antitubercular Agents. Pharmaceuticals (Basel, Switzerland) 14 (2) (2021)
Asma Farjallah, Laurent Roberto Chiarelli, Martin Forbak, Giulia Degiacomi, Mathieu Danel, Fernanda Goncalves, Chantal Carayon, Cendrine Seguin, Marco Fumagalli, Monika Záhorszká, Elodie Vega, Souhir Abid, Anna Grzegorzewicz, Mary Jackson, Antonio Peixoto, Jana Korduláková, Maria Rosalia Pasca, Christian Lherbet, Stefan Chassaing
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis. ACS infectious diseases 7 (3) (2021)
Dongguang Fan, Bin Wang, Giovanni Stelitano, Karin Savková, Rui Shi, Stanislav Huszár, Quanquan Han, Katarína Mikušová, Laurent Roberto Chiarelli, Yu Lu, Chunhua Qiao
Structural and Activity Relationships of 6-Sulfonyl-8-Nitrobenzothiazinones as Antitubercular Agents. Journal of medicinal chemistry 64 (19) (2021)
Giulia Degiacomi, Laurent Roberto Chiarelli, Deborah Recchia, Elena Petricci, Beatrice Gianibbi, Ersilia Vita Fiscarelli, Lanfranco Fattorini, Fabrizio Manetti, Maria Rosalia Pasca
The Antimalarial Mefloquine Shows Activity against Mycobacterium abscessus, Inhibiting Mycolic Acid Metabolism. International journal of molecular sciences 22 (16) (2021)
Silvia Buroni, Laurent Roberto Chiarelli
Antivirulence compounds: a future direction to overcome antibiotic resistance? Future microbiology 15 (2021)
Giovanni Stelitano, Jose Camilla Sammartino, Laurent Roberto Chiarelli
Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis. Molecules (Basel, Switzerland) 25 (5) (2020)
Matteo Mori, Giovanni Stelitano, Arianna Gelain, Elena Pini, Laurent Roberto Chiarelli, Jose Camilla Sammartino, Giulio Poli, Tiziano Tuccinardi, Giangiacomo Beretta, Alessio Porta, Marco Bellinzoni, Stefania Villa, Fiorella Meneghetti
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design. Journal of medicinal chemistry 63 (13) (2020)
Andrea Sass, Lisa Slachmuylders, Heleen Van Acker, Ian Vandenbussche, Lisa Ostyn, Mona Bové, Aurélie Crabbé, Laurent Roberto Chiarelli, Silvia Buroni, Filip Van Nieuwerburgh, Emmanuel Abatih, Tom Coenye
Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms. Antimicrobial agents and chemotherapy 63 (4) (2019)
Tasia Joy Lightly, Kara L Frejuk, Marie-Christine Groleau, Laurent Roberto Chiarelli, Cor Ras, Silvia Buroni, Éric Déziel, John L Sorensen, Silvia T Cardona
Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia. Applied and environmental microbiology 85 (24) (2019)
Laurent Roberto Chiarelli, Matteo Mori, Giangiacomo Beretta, Arianna Gelain, Elena Pini, Jose Camilla Sammartino, Giovanni Stelitano, Daniela Barlocco, Luca Costantino, Margherita Lapillo, Giulio Poli, Isabella Caligiuri, Flavio Rizzolio, Marco Bellinzoni, Tiziano Tuccinardi, Stefania Villa, Fiorella Meneghetti
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Laurent Roberto Chiarelli, Elena G Salina, Giorgia Mori, Tatyana Azhikina, Olga Riabova, Alexander Lepioshkin, Artem Grigorov, Martin Forbak, Jan Madacki, Beatrice Silvia Orena, Marcello Manfredi, Fabio Gosetti, Arianna Buzzi, Giulia Degiacomi, José Camilla Sammartino, Emilio Marengo, Jana Korduláková, Giovanna Riccardi, Katarína Mikušová, Vadim Makarov, Maria Rosalia Pasca
New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053. ACS infectious diseases 6 (2) (2019)
Andrew M Hogan, Viola C Scoffone, Vadim Makarov, April S Gislason, Haben Tesfu, Maria S Stietz, Ann Karen C Brassinga, Michael Domaratzki, Xuan Li, Alberto Azzalin, Marco Biggiogera, Olga Riabova, Natalia Monakhova, Laurent Roberto Chiarelli, Giovanna Riccardi, Silvia Buroni, Silvia T Cardona
Competitive Fitness of Essential Gene Knockdowns Reveals a Broad-Spectrum Antibacterial Inhibitor of the Cell Division Protein FtsZ. Antimicrobial agents and chemotherapy 62 (12) (2018)
Elena Pini, Giulio Poli, Tiziano Tuccinardi, Laurent Roberto Chiarelli, Matteo Mori, Arianna Gelain, Luca Costantino, Stefania Villa, Fiorella Meneghetti, Daniela Barlocco
New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies. Molecules (Basel, Switzerland) 23 (7) (2018)
Laurent Roberto Chiarelli, Giorgia Mori, Beatrice Silvia Orena, Marta Esposito, Thomas Lane, Ana Luisa de Jesus Lopes Ribeiro, Giulia Degiacomi, Júlia Zemanová, Sára Szádocka, Stanislav Huszár, Zuzana Palčeková, Marcello Manfredi, Fabio Gosetti, Joël Lelièvre, Lluis Ballell, Elena Kazakova, Vadim Makarov, Emilio Marengo, Katarina Mikusova, Stewart T Cole, Giovanna Riccardi, Sean Ekins, Maria Rosalia Pasca
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK. Scientific reports 8 (1) (2018)
Marta Esposito, Sára Szadocka, Giulia Degiacomi, Beatrice S Orena, Giorgia Mori, Valentina Piano, Francesca Boldrin, Júlia Zemanová, Stanislav Huszár, David Barros, Sean Ekins, Joel Lelièvre, Riccardo Manganelli, Andrea Mattevi, Maria Rosalia Pasca, Giovanna Riccardi, Lluis Ballell, Katarína Mikušová, Laurent Roberto Chiarelli
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors. ACS infectious diseases 3 (6) (2017)
Aygun Israyilova, Silvia Buroni, Federico Forneris, Viola Camilla Scoffone, Namiq Q Shixaliyev, Giovanna Riccardi, Laurent Roberto Chiarelli
Biochemical Characterization of Glutamate Racemase-A New Candidate Drug Target against Burkholderia cenocepacia Infections. PloS one 11 (11) (2016)

Laurent Roberto Chiarelli.css-eqlu8i{font-size:small;padding-left:4px;} (Laurent Robert Chiarelli, Laurent R Chiarelli)

Publication Activity (10 Years)

Top Topics

Top Venues

Laurent Roberto Chiarelli (Laurent Robert Chiarelli, Laurent R Chiarelli)