Li-Huei Tsai

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 79

Top Venues

Nature neuroscience

Nature

Nature communications

Cell research

This page only lists publications with an associated author ORCID identifier.

Publications

TaeHyun Kim, Benjamin T James, Martin C Kahn, Cristina Blanco-Duque, Fatema Abdurrob, Md Rezaul Islam, Nicolas S Lavoie, Manolis Kellis, Li-Huei Tsai
Gamma entrainment using audiovisual stimuli alleviates chemobrain pathology and cognitive impairment induced by chemotherapy in mice. Science translational medicine 16 (737) (2024)
Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J Middleton, Arthur J Y Huang, Li-Huei Tsai, Thomas J McHugh
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations. Nature communications 15 (1) (2024)
Alexa Pichet Binette, Chris Gaiteri, Malin Wennström, Atul Kumar, Ines Hristovska, Nicola Spotorno, Gemma Salvadó, Olof Strandberg, Hansruedi Mathys, Li-Huei Tsai, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Shorena Janelidze, Erik Stomrud, Jacob W Vogel, Oskar Hansson
Proteomic changes in Alzheimer disease associated with progressive Aβ plaque and tau tangle pathologies. Nature neuroscience (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research (2024)
Daniela Rodrígues-Amorím, P Lorenzo Bozzelli, TaeHyun Kim, Liwang Liu, Oliver Gibson, Cheng-Yi Yang, Mitchell H Murdock, Fabiola Galiana-Melendez, Brooke Schatz, Alexis Davison, Md Rezaul Islam, Dong Shin Park, Ravikiran M Raju, Fatema Abdurrob, Alissa J Nelson, Jian Min Ren, Vicky Yang, Matthew P Stokes, Li-Huei Tsai
Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice. Nature communications 15 (1) (2024)
Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J Middleton, Arthur J Y Huang, Li-Huei Tsai, Thomas J McHugh
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations. Nature communications 15 (1) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Daniela Rodrígues-Amorím, P Lorenzo Bozzelli, TaeHyun Kim, Liwang Liu, Oliver Gibson, Cheng-Yi Yang, Mitchell H Murdock, Fabiola Galiana-Melendez, Brooke Schatz, Alexis Davison, Md Rezaul Islam, Dong Shin Park, Ravikiran M Raju, Fatema Abdurrob, Alissa J Nelson, Jian Min Ren, Vicky Yang, Matthew P Stokes, Li-Huei Tsai
Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice. Nature communications 15 (1) (2024)
Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J Middleton, Arthur J Y Huang, Li-Huei Tsai, Thomas J McHugh
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations. Nature communications 15 (1) (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research 34 (5) (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature 632 (8026) (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J Middleton, Arthur J Y Huang, Li-Huei Tsai, Thomas J McHugh
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations. Nature communications 15 (1) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024)
Daniela Rodrígues-Amorím, P Lorenzo Bozzelli, TaeHyun Kim, Liwang Liu, Oliver Gibson, Cheng-Yi Yang, Mitchell H Murdock, Fabiola Galiana-Melendez, Brooke Schatz, Alexis Davison, Md Rezaul Islam, Dong Shin Park, Ravikiran M Raju, Fatema Abdurrob, Alissa J Nelson, Jian Min Ren, Vicky Yang, Matthew P Stokes, Li-Huei Tsai
Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice. Nature communications 15 (1) (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature 632 (8026) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature 632 (8026) (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research 34 (5) (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature (2024)
TaeHyun Kim, Benjamin T James, Martin C Kahn, Cristina Blanco-Duque, Fatema Abdurrob, Md Rezaul Islam, Nicolas S Lavoie, Manolis Kellis, Li-Huei Tsai
Gamma entrainment using audiovisual stimuli alleviates chemobrain pathology and cognitive impairment induced by chemotherapy in mice. Science translational medicine 16 (737) (2024)
Alexa Pichet Binette, Chris Gaiteri, Malin Wennström, Atul Kumar, Ines Hristovska, Nicola Spotorno, Gemma Salvadó, Olof Strandberg, Hansruedi Mathys, Li-Huei Tsai, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Shorena Janelidze, Erik Stomrud, Jacob W Vogel, Oskar Hansson
Proteomic changes in Alzheimer's disease associated with progressive Aβ plaque and tau tangle pathologies. Nature neuroscience (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research 34 (5) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature 632 (8026) (2024)
P Lorenzo Bozzelli, Li-Huei Tsai
Treating insomnia with 40 Hz light flicker. Cell research 34 (5) (2024)
Mitchell H Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C Kahn, TaeHyun Kim, Nicolas S Lavoie, Matheus B Victor, Md Rezaul Islam, Fabiola Galiana-Melendez, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla Anne Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D Piatkevich, Edward S Boyden, Li-Huei Tsai
Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature 627 (8002) (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature (2024)
Cinzia Vicidomini, Travis D Goode, Kathleen M McAvoy, Ruilin Yu, Conor H Beveridge, Sanjay N Iyer, Matheus B Victor, Noelle Leary, Liam Evans, Michael J Steinbaugh, Zon Weng Lai, Marina C Lyon, Manuel Rico F S Silvestre, Gracia Bonilla, Ruslan I Sadreyev, Tobias C Walther, Shannan Ho Sui, Takaomi C Saido, Kei Yamamoto, Makoto Murakami, Li-Huei Tsai, Gaurav Chopra, Amar Sahay
An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience. bioRxiv : the preprint server for biology (2024)
Hansruedi Mathys, Carles A Boix, Leyla Anne Akay, Ziting Judy Xia, Jose Davila-Velderrain, Ayesha P Ng, Xueqiao Jiang, Ghada Abdelhady, Kyriaki Galani, Julio Mantero, Neil Band, Benjamin T James, Sudhagar Babu, Fabiola Galiana-Melendez, Kate Louderback, Dmitry Prokopenko, Rudolph E Tanzi, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-cell multiregion dissection of Alzheimer's disease. Nature (2024)
Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J Middleton, Arthur J Y Huang, Li-Huei Tsai, Thomas J McHugh
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations. Nature communications 15 (1) (2024)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Nimrod Miller, Zhaofa Xu, Katharina A Quinlan, Amy Ji, Jered V McGivern, Zhihua Feng, Han Shi, Chien-Ping Ko, Li-Huei Tsai, Charles J Heckman, Allison D Ebert, Yongchao C Ma
Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America 120 (47) (2023)
Mitchell H Murdock, Li-Huei Tsai
Insights into Alzheimer's disease from single-cell genomic approaches. Nature neuroscience (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience (2023)
Na Sun, Leyla Anne Akay, Mitchell H Murdock, Yongjin Park, Fabiola Galiana-Melendez, Adele Bubnys, Kyriaki Galani, Hansruedi Mathys, Xueqiao Jiang, Ayesha P Ng, David A Bennett, Li-Huei Tsai, Manolis Kellis
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease. Nature neuroscience (2023)
Mitchell H Murdock, Li-Huei Tsai
Insights into Alzheimer's disease from single-cell genomic approaches. Nature neuroscience 26 (2) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Mitchell H Murdock, Li-Huei Tsai
Insights into Alzheimer's disease from single-cell genomic approaches. Nature neuroscience 26 (2) (2023)
Wen-Chin Huang, Zhuyu Peng, Mitchell H Murdock, Liwang Liu, Hansruedi Mathys, Jose Davila-Velderrain, Xueqiao Jiang, Maggie Chen, Ayesha P Ng, TaeHyun Kim, Fatema Abdurrob, Fan Gao, David A Bennett, Manolis Kellis, Li-Huei Tsai
Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease. Science translational medicine 15 (692) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Mitchell H Murdock, Li-Huei Tsai
Insights into Alzheimer's disease from single-cell genomic approaches. Nature neuroscience 26 (2) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience (2023)
William T Ralvenius, Alison E Mungenast, Hannah Woolf, Margaret M Huston, Tyler Z Gillingham, Stephen K Godin, Jay Penney, Hugh P Cam, Fan Gao, Celia G Fernandez, Barbara Czako, Yaima Lightfoot, William J Ray, Adrian Beckmann, Alison Mary Goate, Edoardo Marcora, Carmen Romero-Molina, Pinar Ayata, Anne Schaefer, Elizabeta Gjoneska, Li-Huei Tsai
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation. The Journal of experimental medicine 220 (11) (2023)
Joe C Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S Torres, Gillian K Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T Gill, Ravikiran M Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E Tracy, Rajiv R Ratan, Li-Huei Tsai, Subhash C Sinha, Li Gan
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nature neuroscience 26 (5) (2023)
Na Sun, Leyla Anne Akay, Mitchell H Murdock, Yongjin Park, Fabiola Galiana-Melendez, Adele Bubnys, Kyriaki Galani, Hansruedi Mathys, Xueqiao Jiang, Ayesha P Ng, David A Bennett, Li-Huei Tsai, Manolis Kellis
Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease. Nature neuroscience (2023)
Mitchell H Murdock, Li-Huei Tsai
Insights into Alzheimer's disease from single-cell genomic approaches. Nature neuroscience 26 (2) (2023)
Ping-Chieh Pao, Li-Huei Tsai
Histone Deacetylases 1 and 2 in Memory Function. ACS chemical neuroscience 13 (7) (2022)
Neeraj Singh, Marc R Benoit, John Zhou, Brati Das, Jose Davila-Velderrain, Manolis Kellis, Li-Huei Tsai, Xiangyou Hu, Riqiang Yan
BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1. Science advances 8 (24) (2022)
Gloria Colombo, Ryan John A Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero, Jens Agerberg, Hansruedi Mathys, Li-Huei Tsai, Wojciech Chachólski, Kathryn Hess, Sandra Siegert
A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes. Nature neuroscience 25 (10) (2022)
Rebecca L Pinals, Li-Huei Tsai
Building in vitro models of the brain to understand the role of <i>APOE</i> in Alzheimer's disease. Life science alliance 5 (11) (2022)
Rebecca L Pinals, Li-Huei Tsai
Correction: Building in vitro models of the brain to understand the role of APOE in Alzheimer's disease. Life science alliance 6 (2) (2022)
Joel W Blanchard, Leyla Anne Akay, Jose Davila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Shawn M Davidson, Audrey Effenberger, Chih-Yu Chen, Kristal Maner-Smith, Ihab Hajjar, Eric A Ortlund, Michael Bula, Emre Agbas, Ayesha Ng, Xueqiao Jiang, Martin Kahn, Cristina Blanco-Duque, Nicolas Lavoie, Liwang Liu, Ricardo Reyes, Yuan-Ta Lin, Tak Ko, Lea R'Bibo, William T Ralvenius, David A Bennett, Hugh P Cam, Manolis Kellis, Li-Huei Tsai
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. Nature 611 (7937) (2022)
Gwyneth M Welch, Carles A Boix, Eloi Schmauch, Jose Davila-Velderrain, Matheus B Victor, Vishnu Dileep, P Lorenzo Bozzelli, Qiao Su, Jemmie D Cheng, Audrey Lee, Noelle S Leary, Andreas R Pfenning, Manolis Kellis, Li-Huei Tsai
Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Science advances 8 (39) (2022)
Murat Yildirim, Chloe Delepine, Danielle Feldman, Vincent A Pham, Stephanie Chou, Jacque Ip, Alexi Nott, Li-Huei Tsai, Guo-Li Ming, Peter T C So, Mriganka Sur
Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome. eLife 11 (2022)
Gwyneth M Welch, Li-Huei Tsai
Mechanisms of DNA damage-mediated neurotoxicity in neurodegenerative disease. EMBO reports 23 (6) (2022)
Deblina Sarkar, Jinyoung Kang, Asmamaw T Wassie, Margaret E Schroeder, Zhuyu Peng, Tyler B Tarr, Ai-Hui Tang, Emily D Niederst, Jennie Z Young, Hanquan Su, Demian Park, Peng Yin, Li-Huei Tsai, Thomas A Blanpied, Edward S Boyden
Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy. Nature biomedical engineering 6 (9) (2022)
Diane Chan, Ho-Jun Suk, Brennan L Jackson, Noah E P Milman, Danielle Stark, Elizabeth B Klerman, Erin Kitchener, Vanesa S Fernandez Avalos, Gabrielle de Weck, Arit Banerjee, Sara D Beach, Joel Blanchard, Colton Stearns, Aaron D Boes, Brandt Uitermarkt, Phillip Gander, Matthew Howard, Eliezer J Sternberg, Alfonso Nieto-Castanon, Sheeba Anteraper, Susan Whitfield-Gabrieli, Emery N Brown, Edward S Boyden, Bradford C Dickerson, Li-Huei Tsai
Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies. PloS one 17 (12) (2022)
Grzegorz Sienski, Priyanka Narayan, Julia Maeve Bonner, Nora Kory, Sebastian Boland, Aleksandra A Arczewska, William T Ralvenius, Leyla Anne Akay, Elana Lockshin, Liang He, Blerta Milo, Agnese Graziosi, Valeriya Baru, Caroline A Lewis, Manolis Kellis, David M Sabatini, Li-Huei Tsai, Susan Lindquist
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia. Science translational medicine 13 (583) (2021)
Nader Morshed, William T Ralvenius, Alexi Nott, L Ashley Watson, Felicia H Rodriguez, Leyla Anne Akay, Brian A Joughin, Ping-Chieh Pao, Jay Penney, Lauren LaRocque, Diego Mastroeni, Li-Huei Tsai, Forest M White
Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration. Molecular systems biology 16 (12) (2021)
Joel W Blanchard, Matheus B Victor, Li-Huei Tsai
Dissecting the complexities of Alzheimer disease with in vitro models of the human brain. Nature reviews. Neurology (2021)
Ryan T Stott, Oleg Kritsky, Li-Huei Tsai
Profiling DNA break sites and transcriptional changes in response to contextual fear learning. PloS one 16 (7) (2021)
Scarlett J Barker, Ravikiran M Raju, Noah E P Milman, Jun Wang, Jose Davila-Velderrain, Fatima Gunter-Rahman, Cameron C Parro, P Lorenzo Bozzelli, Fatema Abdurrob, Karim Abdelaal, David A Bennett, Manolis Kellis, Li-Huei Tsai
MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration. Science translational medicine 13 (618) (2021)
Leyla Anne Akay, Audrey H Effenberger, Li-Huei Tsai
Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function. Genes & development 35 (3-4) (2021)
Asaf Marco, Hiruy S Meharena, Vishnu Dileep, Ravikiran M Raju, Jose Davila-Velderrain, Amy Letao Zhang, Chinnakkaruppan Adaikkan, Jennie Z Young, Fan Gao, Manolis Kellis, Li-Huei Tsai
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble. Nature neuroscience 23 (12) (2020)
Ravikiran M Raju, Li-Huei Tsai
The complexity of neuroinflammation at single-cell resolution. Nature reviews. Neurology 15 (5) (2020)
Ping-Chieh Pao, Debasis Patnaik, L Ashley Watson, Fan Gao, Ling Pan, Jun Wang, Chinnakkaruppan Adaikkan, Jay Penney, Hugh P Cam, Wen-Chin Huang, Lorena Pantano, Audrey Lee, Alexi Nott, Trongha X Phan, Elizabeta Gjoneska, Sara Elmsaouri, Stephen J Haggarty, Li-Huei Tsai
HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. Nature communications 11 (1) (2020)
Joel W Blanchard, Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Alexander Frank, Matheus B Victor, Julia Maeve Bonner, Hansruedi Mathys, Yuan-Ta Lin, Tak Ko, David A Bennett, Hugh P Cam, Manolis Kellis, Li-Huei Tsai
Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. Nature medicine 26 (6) (2020)
Jinsoo Seo, Oleg Kritskiy, L Ashley Watson, Scarlett J Barker, Dilip Dey, Waseem K Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney, M Catarina Silva, Steven D Sheridan, Diane Lucente, James F Gusella, Bradford C Dickerson, Stephen J Haggarty, Li-Huei Tsai
Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (41) (2017)
Jay Penney, Jinsoo Seo, Oleg Kritskiy, Sara Elmsaouri, Fan Gao, Ping-Chieh Pao, Susan C Su, Li-Huei Tsai
Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (36) (2017)

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Li-Huei Tsai