Lu Lu

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 101

Top Venues

Signal transduction and targeted therapy

Viruses

Cell research

Cellular & molecular immunology

Fudan University

Tsinghua University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fudan University Dec 13 2014

China

Professor :: School of Basic Medical Sciences

Fudan University Mar 01 2011 - Dec 12 2014

China

Associate Professor :: School of Basic Medical Sciences

New York Blood Center Aug 01 2009 - Mar 01 2011

United States

Postdoctor :: Lindsley F. Kimball Research Institute

Tsinghua University Jan 10 2009 - Aug 01 2009

China

Research Assistant :: School of life science

Education History

Tsinghua University Sep 01 2004 - Jan 09 2009

China

PHD :: School of life sicence

Wuhan University Sep 01 2000 - Jun 25 2004

China

BSC :: College of life science

Publications

Kai Wang, Dagui Chen, Chenxi Zhang, Lu Lu, Fusheng Shang, Yinghua Li
Polyethylene Glycol-Modified Cationic Liposome as a Promising Nano Spray for Acute Pneumonia Treatment. Polymers 16 (10) (2024)
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein. Nature communications 15 (1) (2024)
Lijue Wang, Fanke Jiao, Hanxiao Jiang, Yitao Yang, Ziqi Huang, Qian Wang, Wei Xu, Yun Zhu, Shuai Xia, Shibo Jiang, Lu Lu
Fusogenicity of SARS-CoV-2 BA.2.86 subvariant and its sensitivity to the prokaryotic recombinant EK1 peptide. Cell discovery 10 (1) (2024)
Suiyi Tan, Wenjuan Li, Chan Yang, Qingping Zhan, Kunyu Lu, Jun Liu, Yong-Mei Jin, Jin-Song Bai, Lin Wang, Jinqing Li, Zhaofeng Li, Fei Yu, Yu-Ye Li, Yue-Xun Duan, Lu Lu, Tong Zhang, Jiaqi Wei, Lin Li, Yong-Tang Zheng, Shibo Jiang, Shu-Wen Liu
gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity. Cellular & molecular immunology 21 (5) (2024)
Lijue Wang, Fanke Jiao, Hanxiao Jiang, Yitao Yang, Ziqi Huang, Qian Wang, Wei Xu, Yun Zhu, Shuai Xia, Shibo Jiang, Lu Lu
Fusogenicity of SARS-CoV-2 BA.2.86 subvariant and its sensitivity to the prokaryotic recombinant EK1 peptide. Cell discovery 10 (1) (2024)
Kunlan Zuo, Wanying Gao, Zongzhen Wu, Lei Zhang, Jiafeng Wang, Xuefan Yuan, Chun Li, Qiangyu Xiang, Lu Lu, Huan Liu
Evolution of Virology: Science History through Milestones and Technological Advancements. Viruses 16 (3) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Yongkang Chen, Yuan Li, Lu Lu, Peng Zou
Zafirlukast, as a viral inactivator, potently inhibits infection of several flaviviruses, including Zika virus, dengue virus, and yellow fever virus. Antimicrobial agents and chemotherapy 68 (7) (2024)
Yongkang Chen, Yuan Li, Lu Lu, Peng Zou
Zafirlukast, as a viral inactivator, potently inhibits infection of several flaviviruses, including Zika virus, dengue virus, and yellow fever virus. Antimicrobial agents and chemotherapy 68 (7) (2024)
Wenjie Qu, Chen Hua, Yaping Wang, Yan Wang, Lu Zhang, Zhiheng Wang, Wenqian Shi, Fang Chen, Zhiyong Wu, Qian Wang, Lu Lu, Shibo Jiang, Long Sui, Yanyun Li
Lineage Replacement and Genetic Changes of Four HR-HPV Types during the Period of Vaccine Coverage: A Six-Year Retrospective Study in Eastern China. Vaccines 12 (4) (2024)
Suiyi Tan, Wenjuan Li, Chan Yang, Qingping Zhan, Kunyu Lu, Jun Liu, Yong-Mei Jin, Jin-Song Bai, Lin Wang, Jinqing Li, Zhaofeng Li, Fei Yu, Yu-Ye Li, Yue-Xun Duan, Lu Lu, Tong Zhang, Jiaqi Wei, Lin Li, Yong-Tang Zheng, Shibo Jiang, Shu-Wen Liu
gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity. Cellular & molecular immunology 21 (5) (2024)
Wenbo Sun, Tingyu Yang, Fengming Sun, Panhong Liu, Ji Gao, Xianmei Lan, Wei Xu, Yuhong Pang, Tong Li, Cuifeng Li, Qingtai Liang, Haoze Chen, Xiaohang Liu, Wenting Tan, Huanhuan Zhu, Fang Wang, Fanjun Cheng, Weiwei Zhai, Han-Na Kim, Jingren Zhang, Linqi Zhang, Lu Lu, Qiaoran Xi, Guohong Deng, Yanyi Huang, Xin Jin, Xiangjun Chen, Wanli Liu
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms. Nature immunology (2024)
Lijue Wang, Fanke Jiao, Hanxiao Jiang, Yitao Yang, Ziqi Huang, Qian Wang, Wei Xu, Yun Zhu, Shuai Xia, Shibo Jiang, Lu Lu
Fusogenicity of SARS-CoV-2 BA.2.86 subvariant and its sensitivity to the prokaryotic recombinant EK1 peptide. Cell discovery 10 (1) (2024)
Yingdan Wang, Aihua Hao, Ping Ji, Yunping Ma, Zhaoyong Zhang, Jiali Chen, Qiyu Mao, Xinyi Xiong, Palizhati Rehati, Yajie Wang, Yanqun Wang, Yumei Wen, Lu Lu, Zhenguo Chen, Jin-Cun Zhao, Fan Wu, Jinghe Huang, Lei Sun
A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses. Nature communications 15 (1) (2024)
Kunlan Zuo, Wanying Gao, Zongzhen Wu, Lei Zhang, Jiafeng Wang, Xuefan Yuan, Chun Li, Qiangyu Xiang, Lu Lu, Huan Liu
Evolution of Virology: Science History through Milestones and Technological Advancements. Viruses 16 (3) (2024)
Kai Wang, Dagui Chen, Chenxi Zhang, Lu Lu, Fusheng Shang, Yinghua Li
Polyethylene Glycol-Modified Cationic Liposome as a Promising Nano Spray for Acute Pneumonia Treatment. Polymers 16 (10) (2024)
Kunlan Zuo, Wanying Gao, Zongzhen Wu, Lei Zhang, Jiafeng Wang, Xuefan Yuan, Chun Li, Qiangyu Xiang, Lu Lu, Huan Liu
Evolution of Virology: Science History through Milestones and Technological Advancements. Viruses 16 (3) (2024)
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor. mBio (2024)
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor. mBio 15 (5) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Yingdan Wang, Aihua Hao, Ping Ji, Yunping Ma, Zhaoyong Zhang, Jiali Chen, Qiyu Mao, Xinyi Xiong, Palizhati Rehati, Yajie Wang, Yanqun Wang, Yumei Wen, Lu Lu, Zhenguo Chen, Jin-Cun Zhao, Fan Wu, Jinghe Huang, Lei Sun
A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses. Nature communications 15 (1) (2024)
Yongkang Chen, Yuan Li, Lu Lu, Peng Zou
Zafirlukast, as a viral inactivator, potently inhibits infection of several flaviviruses, including Zika virus, dengue virus, and yellow fever virus. Antimicrobial agents and chemotherapy 68 (7) (2024)
Suiyi Tan, Wenjuan Li, Chan Yang, Qingping Zhan, Kunyu Lu, Jun Liu, Yong-Mei Jin, Jin-Song Bai, Lin Wang, Jinqing Li, Zhaofeng Li, Fei Yu, Yu-Ye Li, Yue-Xun Duan, Lu Lu, Tong Zhang, Jiaqi Wei, Lin Li, Yong-Tang Zheng, Shibo Jiang, Shu-Wen Liu
gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity. Cellular & molecular immunology (2024)
Kunlan Zuo, Wanying Gao, Zongzhen Wu, Lei Zhang, Jiafeng Wang, Xuefan Yuan, Chun Li, Qiangyu Xiang, Lu Lu, Huan Liu
Evolution of Virology: Science History through Milestones and Technological Advancements. Viruses 16 (3) (2024)
Suiyi Tan, Wenjuan Li, Chan Yang, Qingping Zhan, Kunyu Lu, Jun Liu, Yong-Mei Jin, Jin-Song Bai, Lin Wang, Jinqing Li, Zhaofeng Li, Fei Yu, Yu-Ye Li, Yue-Xun Duan, Lu Lu, Tong Zhang, Jiaqi Wei, Lin Li, Yong-Tang Zheng, Shibo Jiang, Shu-Wen Liu
gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity. Cellular & molecular immunology 21 (5) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein. Nature communications 15 (1) (2024)
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor. mBio 15 (5) (2024)
Yongkang Chen, Yuan Li, Lu Lu, Peng Zou
Zafirlukast, as a viral inactivator, potently inhibits infection of several flaviviruses, including Zika virus, dengue virus, and yellow fever virus. Antimicrobial agents and chemotherapy (2024)
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein. Nature communications 15 (1) (2024)
Yongkang Chen, Xiaohong Li, Fengyang Han, Beihong Ji, Yuan Li, Jingjing Yan, Min Wang, Jun Fan, Shuye Zhang, Lu Lu, Peng Zou
The nucleoside analog 4'-fluorouridine suppresses the replication of multiple enteroviruses by targeting 3D polymerase. Antimicrobial agents and chemotherapy (2024)
Wenjie Qu, Chen Hua, Yaping Wang, Yan Wang, Lu Zhang, Zhiheng Wang, Wenqian Shi, Fang Chen, Zhiyong Wu, Qian Wang, Lu Lu, Shibo Jiang, Long Sui, Yanyun Li
Lineage Replacement and Genetic Changes of Four HR-HPV Types during the Period of Vaccine Coverage: A Six-Year Retrospective Study in Eastern China. Vaccines 12 (4) (2024)
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Geng-Fu Xiao, Zihe Rao, Lu Lu, Lei-Ke Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1. Signal transduction and targeted therapy 9 (1) (2024)
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor. mBio 15 (5) (2024)
Suiyi Tan, Wenjuan Li, Chan Yang, Qingping Zhan, Kunyu Lu, Jun Liu, Yong-Mei Jin, Jin-Song Bai, Lin Wang, Jinqing Li, Zhaofeng Li, Fei Yu, Yu-Ye Li, Yue-Xun Duan, Lu Lu, Tong Zhang, Jiaqi Wei, Lin Li, Yong-Tang Zheng, Shibo Jiang, Shu-Wen Liu
gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity. Cellular & molecular immunology (2024)
Najing Cao, Yanxing Cai, Xin Huang, Hanxiao Jiang, Ziqi Huang, Lixiao Xing, Lu Lu, Shibo Jiang, Wei Xu
Inhibition of influenza A virus and SARS-CoV-2 infection or co-infection by griffithsin and griffithsin-based bivalent entry inhibitor. mBio (2024)
Zezhong Liu, Jie Zhou, Xinling Wang, Wei Xu, Zheng Teng, Hongyou Chen, Min Chen, Guangxu Zhang, Yuanzhou Wang, Jinghe Huang, Qian Wang, Shibo Jiang, Lu Lu
A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Xiaojie Su, Ziqi Huang, Wei Xu, Qian Wang, Lixiao Xing, Lu Lu, Shibo Jiang, Shuai Xia
IgG Fc-Binding Peptide-Conjugated Pan-CoV Fusion Inhibitor Exhibits Extended In Vivo Half-Life and Synergistic Antiviral Effect When Combined with Neutralizing Antibodies. Biomolecules 13 (9) (2023)
Mengwen Huang, Xingchao Pan, Xinling Wang, Qingfei Ren, Bei Tong, Xianchi Dong, GaoXiang Ge, Lu Lu, Shibo Jiang, Jian-Feng Chen
Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Chao Wang, Qing Li, Lujia Sun, Xinling Wang, Huan Wang, Wenpeng Zhang, Jiahui Li, Yang Liu, Lu Lu, Shibo Jiang
An Artificial Peptide-Based Bifunctional HIV-1 Entry Inhibitor That Interferes with Viral Glycoprotein-41 Six-Helix Bundle Formation and Antagonizes CCR5 on the Host Cell Membrane. Viruses 15 (5) (2023)
Shuai Xia, Lijue Wang, Fanke Jiao, Xueying Yu, Wei Xu, Ziqi Huang, Xicheng Li, Qian Wang, Yun Zhu, Qiuhong Man, Shibo Jiang, Lu Lu
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors. Emerging microbes & infections (2023)
Mengwen Huang, Xingchao Pan, Xinling Wang, Qingfei Ren, Bei Tong, Xianchi Dong, GaoXiang Ge, Lu Lu, Shibo Jiang, Jian-Feng Chen
Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Xinling Wang, Lujia Sun, Zezhong Liu, Lixiao Xing, Yun Zhu, Wei Xu, Shuai Xia, Lu Lu, Shibo Jiang
An engineered recombinant protein containing three structural domains in SARS-CoV-2 S2 protein has potential to act as a pan-human coronavirus entry inhibitor or vaccine antigen. Emerging microbes & infections (2023)
Kuo Liu, Muxue Tang, Wei Xu, Xinfeng Meng, Hengwei Jin, Maoying Han, Jing Pu, Yutang Li, Fanke Jiao, Ruilin Sun, Ruling Shen, Kathy O Lui, Lu Lu, Bin Zhou
An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Fanlin Li, Wei Xu, Xiaoqing Zhang, Wanting Wang, Shan Su, Ping Han, Haiyong Wang, Yanqin Xu, Min Li, Lilv Fan, Huihui Zhang, Qiang Dai, Hao Lin, Xinyue Qi, Jie Liang, Xin Wang, Shibo Jiang, You-Hua Xie, Lu Lu, Xuanming Yang
A spike-targeting bispecific T cell engager strategy provides dual layer protection against SARS-CoV-2 infection in vivo. Communications biology 6 (1) (2023)
Ling Xu, Chao Wang, Wei Xu, Lixiao Xing, Jie Zhou, Jing Pu, Mingming Fu, Lu Lu, Shibo Jiang, Qian Wang
A dePEGylated Lipopeptide-Based Pan-Coronavirus Fusion Inhibitor Exhibits Potent and Broad-Spectrum Anti-HIV-1 Activity without Eliciting Anti-PEG Antibodies. International journal of molecular sciences 24 (11) (2023)
Mengwen Huang, Xingchao Pan, Xinling Wang, Qingfei Ren, Bei Tong, Xianchi Dong, GaoXiang Ge, Lu Lu, Shibo Jiang, Jian-Feng Chen
Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Shuai Xia, Lijue Wang, Fanke Jiao, Xueying Yu, Wei Xu, Ziqi Huang, Xicheng Li, Qian Wang, Yun Zhu, Qiuhong Man, Shibo Jiang, Lu Lu
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors. Emerging microbes & infections 12 (1) (2023)
Shuai Xia, Lijue Wang, Fanke Jiao, Xueying Yu, Wei Xu, Ziqi Huang, Xicheng Li, Qian Wang, Yun Zhu, Qiuhong Man, Shibo Jiang, Lu Lu
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors. Emerging microbes & infections 12 (1) (2023)
Zezhong Liu, Jie Zhou, Xinling Wang, Wei Xu, Zheng Teng, Hongyou Chen, Min Chen, Guangxu Zhang, Yuanzhou Wang, Jinghe Huang, Qian Wang, Shibo Jiang, Lu Lu
A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Xinling Wang, Lu Lu, Shibo Jiang
SARS-CoV-2 Omicron subvariant BA.2.86: limited potential for global spread. Signal transduction and targeted therapy 8 (1) (2023)
Zezhong Liu, Jie Zhou, Xinling Wang, Wei Xu, Zheng Teng, Hongyou Chen, Min Chen, Guangxu Zhang, Yuanzhou Wang, Jinghe Huang, Qian Wang, Shibo Jiang, Lu Lu
A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Shuai Xia, Lijue Wang, Fanke Jiao, Xueying Yu, Wei Xu, Ziqi Huang, Xicheng Li, Qian Wang, Yun Zhu, Qiuhong Man, Shibo Jiang, Lu Lu
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors. Emerging microbes & infections 12 (1) (2023)
Yunping Ma, Qiyu Mao, Yingdan Wang, Zhaoyong Zhang, Jiali Chen, Aihua Hao, Palizhati Rehati, Yanqun Wang, Yumei Wen, Lu Lu, Zhenguo Chen, Jin-Cun Zhao, Fan Wu, Lei Sun, Jinghe Huang
A broadly neutralizing antibody inhibits SARS-CoV-2 variants through a novel mechanism of disrupting spike trimer integrity. Cell research (2023)
Tianyu Lu, Qiuhong Man, Shuai Xia, Xiaohang Liu, Yan Yan, Xueying Yu, Yan Fu, Wanli Liu, Lu Lu, Shibo Jiang, Lize Xiong
Multiple-cohort study of the elderly to determine the immunological characteristics and pathogenic mechanisms of severe community-acquired pneumonia caused by the low-virulence virus SARS-CoV-2 Omicron variant. Cell discovery 9 (1) (2023)
Naru Zhang, Qianting Ji, Zezhong Liu, Kaiming Tang, Yubin Xie, Kangchen Li, Jie Zhou, Sisi Li, Haotian Shang, Zecan Shi, Tianyu Zheng, Jiawei Yao, Lu Lu, Shuo-Feng Yuan, Shibo Jiang
Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta Variant. Viruses 14 (3) (2022)
Jie Zhou, Zezhong Liu, Guangxu Zhang, Wei Xu, Lixiao Xing, Lu Lu, Qian Wang, Shibo Jiang
Development of variant-proof severe acute respiratory syndrome coronavirus 2, pan-sarbecovirus, and pan-β-coronavirus vaccines. Journal of medical virology (2022)
Zezhong Liu, Jasper Fuk-Woo Chan, Jie Zhou, Meiyu Wang, Qian Wang, Guangxu Zhang, Wei Xu, Kenn Ka-Heng Chik, Yilong Zhang, You-Chun Wang, Kwok-Yung Yuen, Lu Lu, Shibo Jiang
A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant. Cell research 32 (5) (2022)
Yuhong Fu, Peiyu Li, Wei Xu, Zezhong Liu, Cong Wang, Qian Wang, Jiayi Tang, Weihua Li, Lu Lu, Shibo Jiang
Chemically Modified Bovine β-Lactoglobulin as a Broad-Spectrum Influenza Virus Entry Inhibitor with the Potential to Combat Influenza Outbreaks. Viruses 14 (9) (2022)
Shuai Xia, Lijue Wang, Yun Zhu, Lu Lu, Shibo Jiang
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages. Signal transduction and targeted therapy 7 (1) (2022)
Jiangchao Xiang, Jie Su, Qiaoshuai Lan, Wenwen Zhao, Yu Zhou, Youwei Xu, Jun Niu, Shuai Xia, Qilian Qi, Sachdev S Sidhu, Lu Lu, Shane Miersch, Bei Yang
Antigenic mapping reveals sites of vulnerability on α-HCoV spike protein. Communications biology 5 (1) (2022)
Shuai Xia, Jasper Fuk-Woo Chan, Lijue Wang, Fanke Jiao, Kenn Ka-Heng Chik, Hin Chu, Qiaoshuai Lan, Wei Xu, Qian Wang, Chao Wang, Kwok-Yung Yuen, Lu Lu, Shibo Jiang
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant. Cell research 32 (4) (2022)
Zezhong Liu, Lu Lu, Shibo Jiang
Up or down: where comes Omicron? Cell research 32 (7) (2022)
Songyi Xue, Xinling Wang, Lei Wang, Wei Xu, Shuai Xia, Lujia Sun, Shaohui Wang, Ning Shen, Ziqi Yang, Bo Huang, Sihao Li, Chuanhai Cao, Laurent Calcul, Xingmin Sun, Lu Lu, Jianfeng Cai, Shibo Jiang
A novel cyclic γ-AApeptide-based long-acting pan-coronavirus fusion inhibitor with potential oral bioavailability by targeting two sites in spike protein. Cell discovery 8 (1) (2022)
Qianyu Duan, Shuai Xia, Fanke Jiao, Qian Wang, Rui Wang, Lu Lu, Shibo Jiang, Wei Xu
A Modified Fibronectin Type III Domain-Conjugated, Long-Acting Pan-Coronavirus Fusion Inhibitor with Extended Half-Life. Viruses 14 (4) (2022)
Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, Longfei Ding, Shuai Xia, Xingchen Chen, Mu Liu, Chenjian Gu, Xiao Lu, Yadong Fu, Shuangfeng Chen, Tianlong Zhang, Yaguang Zhang, Zhuo Yang, Liyan Ma, Wangpeng Gu, Gaowei Hu, Shujuan Du, Renhong Yan, Weihui Fu, Songhua Yuan, Chenli Qiu, Chen Zhao, Xiaoyan Zhang, Yonghui He, Aidong Qu, Xu Zhou, Xiuling Li, Gary Wong, Qiang Deng, Qiang Zhou, Hongzhou Lu, Zhiyang Ling, Jianping Ding, Lu Lu, Jianqing Xu, You-Hua Xie, Bing Sun
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nature microbiology 7 (7) (2022)
Qiaoshuai Lan, Lijue Wang, Fanke Jiao, Lu Lu, Shuai Xia, Shibo Jiang
Pan-coronavirus fusion inhibitors to combat COVID-19 and other emerging coronavirus infectious diseases. Journal of medical virology (2022)
Zezhong Liu, Jie Zhou, Wei Xu, Wei Deng, Yanqun Wang, Meiyu Wang, Qian Wang, Ming Hsieh, Jingming Dong, Xinling Wang, Wei Jin Huang, Lixiao Xing, Miaoling He, Chunlin Tao, You-Hua Xie, Yilong Zhang, You-Chun Wang, Jin-Cun Zhao, Zhenghong Yuan, Chuan Qin, Shibo Jiang, Lu Lu
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs. Cell research 32 (3) (2022)
Jing Pu, Xiao-Yang He, Wei Xu, Cong Wang, Qiaoshuai Lan, Chen Hua, Kai Wang, Lu Lu, Shibo Jiang
The Analogs of Furanyl Methylidene Rhodanine Exhibit Broad-Spectrum Inhibitory and Inactivating Activities against Enveloped Viruses, including SARS-CoV-2 and Its Variants. Viruses 14 (3) (2022)
Yingdan Wang, Wuqiang Zhan, Jiangyan Liu, Yanqun Wang, Xiang Zhang, Meng Zhang, Lin Han, Yunping Ma, Lu Lu, Yumei Wen, Zhenguo Chen, Jin-Cun Zhao, Fan Wu, Lei Sun, Jinghe Huang
A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell research 32 (9) (2022)
Lixiao Xing, Xinfeng Xu, Wei Xu, Zezhong Liu, Xin Shen, Jie Zhou, Ling Xu, Jing Pu, Chan Yang, Yuan Huang, Lu Lu, Shibo Jiang, Shu-Wen Liu
A Five-Helix-Based SARS-CoV-2 Fusion Inhibitor Targeting Heptad Repeat 2 Domain against SARS-CoV-2 and Its Variants of Concern. Viruses 14 (3) (2022)
Qiaoshuai Lan, Jasper Fuk-Woo Chan, Wei Xu, Lijue Wang, Fanke Jiao, Guangxu Zhang, Jing Pu, Jie Zhou, Shuai Xia, Lu Lu, Kwok-Yung Yuen, Shibo Jiang, Qian Wang
A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern. Viruses 14 (3) (2022)
Wei Xu, Zhe Cong, Qianyu Duan, Qian Wang, Shan Su, Rui Wang, Lu Lu, Jing Xue, Shibo Jiang
A Protein-Based, Long-Acting HIV-1 Fusion Inhibitor with an Improved Pharmacokinetic Profile. Pharmaceuticals (Basel, Switzerland) 15 (4) (2022)
Qiaoshuai Lan, Chao Wang, Jie Zhou, Lijue Wang, Fanke Jiao, Yanbo Zhang, Yanxing Cai, Lu Lu, Shuai Xia, Shibo Jiang
25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses. International journal of molecular sciences 22 (21) (2021)
Xinling Wang, Miao Cao, Yanling Wu, Wei Xu, Qian Wang, Tianlei Ying, Lu Lu, Shibo Jiang
Synergistic Effect by Combining a gp120-Binding Protein and a gp41-Binding Antibody to Inactivate HIV-1 Virions and Inhibit HIV-1 Infection. Molecules (Basel, Switzerland) 26 (7) (2021)
Zezhong Liu, Wei Xu, Zhenguo Chen, Wangjun Fu, Wuqiang Zhan, Yidan Gao, Jie Zhou, Yunjiao Zhou, Jianbo Wu, Qian Wang, Xiang Zhang, Aihua Hao, Wei Wu, Qianqian Zhang, Yaming Li, Kaiyue Fan, Ruihong Chen, Qiaochu Jiang, Christian Thomas Mayer, Till Schoofs, Youhua Xie, Shibo Jiang, Yumei Wen, Zhenghong Yuan, Kang Wang, Lu Lu, Lei Sun, Qiao Wang
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein & cell (2021)
Shuai Xia, Zuoling Wen, Lijue Wang, Qiaoshuai Lan, Fanke Jiao, Linhua Tai, Qian Wang, Fei Sun, Shibo Jiang, Lu Lu, Yun Zhu
Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha). Cell discovery 7 (1) (2021)
Qian Wang, Shan Su, Jing Xue, Fei Yu, Jing Pu, Wenwen Bi, Shuai Xia, Yu Meng, Cong Wang, Wenqian Yang, Wei Xu, Yun Zhu, Qinwen Zheng, Chuan Qin, Shibo Jiang, Lu Lu
An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells. Science translational medicine 12 (546) (2021)
Shuai Wang, Zongyang Qiu, Yingnan Hou, Xiya Deng, Wei Xu, Tingting Zheng, Peihan Wu, Shaofang Xie, Weixiang Bian, Chong Zhang, Zewei Sun, Kunpeng Liu, Chao Shan, Aifu Lin, Shibo Jiang, Youhua Xie, Qiang Zhou, Lu Lu, Jing Huang, Xu Li
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells. Cell research 31 (2) (2021)
Fei Li, Ming Han, Pengfei Dai, Wei Xu, Juan He, Xiaoting Tao, Yang Wu, Xinyuan Tong, Xinyi Xia, Wangxin Guo, Yunjiao Zhou, Yunguang Li, Yiqin Zhu, Xiaoyu Zhang, Zhuang Liu, Rebiguli Aji, Xia Cai, Yutang Li, Di Qu, Juliet Chen, Shibo Jiang, Qiao Wang, Hongbin Ji, You-Hua Xie, Yihua Sun, Lu Lu, Wangxin Guo
Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide. Nature communications 12 (1) (2021)
Cheng Li, Xiaolong Tian, Xiaodong Jia, Jinkai Wan, Lu Lu, Shibo Jiang, Fei Lan, Yinying Lu, Yanling Wu, Tianlei Ying
The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2. Signal transduction and targeted therapy 6 (1) (2021)
Shuai Xia, Qiaoshuai Lan, Yun Zhu, Chao Wang, Wei Xu, Yutang Li, Lijue Wang, Fanke Jiao, Jie Zhou, Chen Hua, Qian Wang, Xia Cai, Yang Wu, Jie Gao, Huan Liu, Ge Sun, Jan Münch, Frank Kirchhoff, Zhenghong Yuan, You-Hua Xie, Fei Sun, Shibo Jiang, Lu Lu
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation. Signal transduction and targeted therapy 6 (1) (2021)
Zhenlin Yang, Yulu Wang, Yujia Jin, Yuanfei Zhu, Yanling Wu, Cheng Li, Yu Kong, Wenping Song, Xiaolong Tian, Wuqiang Zhan, Ailing Huang, Shanshan Zhou, Shuai Xia, Xiaoxu Tian, Chao Peng, Cuicui Chen, Yibing Shi, Gaowei Hu, Shujuan Du, Yuyan Wang, You-Hua Xie, Shibo Jiang, Lu Lu, Lei Sun, Yuanlin Song, Tianlei Ying
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants. Signal transduction and targeted therapy 6 (1) (2021)
Chen Hua, Qinhai Ma, Yun Zhu, Shuai Xia, Zezhong Liu, Lin Li, Lu Lu, Nanshan Zhong, Shu-Wen Liu, Zifeng Yang, Shibo Jiang
Repurposing of a clinically used anti-HPV agent to prevent and treat SARS-CoV-2 infection as an intranasal formulation. Signal transduction and targeted therapy 6 (1) (2021)
Xinling Wang, Wei Xu, Gaowei Hu, Shuai Xia, Zhiping Sun, Zezhong Liu, Youhua Xie, Rong Zhang, Shibo Jiang, Lu Lu
RETRACTED ARTICLE: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion. Cellular & molecular immunology (2020)
Shuai Xia, Qiaoshuai Lan, Shan Su, Xinling Wang, Wei Xu, Zezhong Liu, Yun Zhu, Qian Wang, Lu Lu, Shibo Jiang
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin. Signal transduction and targeted therapy 5 (1) (2020)
Ji Wang, Peiyu Li, Yang Yu, Yuhong Fu, Hongye Jiang, Mei X Wu, Zhiping Sun, Shibo Jiang, Lu Lu, Mei X Wu
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science (New York, N.Y.) 367 (6480) (2020)
Liang Guo, Wenwen Bi, Xinling Wang, Wei Xu, Renhong Yan, Yuanyuan Zhang, Kai Zhao, Yaning Li, Mingfeng Zhang, Xia Cai, Shibo Jiang, Youhua Xie, Qiang Zhou, Lu Lu, Bobo Dang
Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. Cell research 31 (1) (2020)
Lang Rao, Shuai Xia, Wei Xu, Rui Tian, Guocan Yu, Chenjian Gu, Pan Pan, Qian-Fang Meng, Xia Cai, Di Qu, Lu Lu, Youhua Xie, Shibo Jiang, Xiaoyuan Shawn Chen
Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines. Proceedings of the National Academy of Sciences of the United States of America 117 (44) (2020)
Xinling Wang, Shuai Xia, Qian Wang, Wei Xu, Weihua Li, Lu Lu, Shibo Jiang
Broad-Spectrum Coronavirus Fusion Inhibitors to Combat COVID-19 and Other Emerging Coronavirus Diseases. International journal of molecular sciences 21 (11) (2020)
Shuai Xia, Yun Zhu, Meiqin Liu, Qiaoshuai Lan, Wei Xu, Yanling Wu, Tianlei Ying, Shuwen Liu, Zhengli Shi, Shibo Jiang, Lu Lu
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein. Cellular & molecular immunology 17 (7) (2020)
Zezhong Liu, Wei Xu, Shuai Xia, Chenjian Gu, Xinling Wang, Qian Wang, Jie Zhou, Yanling Wu, Xia Cai, Di Qu, Tianlei Ying, Youhua Xie, Lu Lu, Zhenghong Yuan, Shibo Jiang
RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response. Signal transduction and targeted therapy 5 (1) (2020)
Zezhong Liu, Shuai Xia, Xinling Wang, Qiaoshuai Lan, Wei Xu, Qian Wang, Shibo Jiang, Lu Lu
Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection. Virologica Sinica 35 (3) (2020)
Shuai Xia, Meiqin Liu, Chao Wang, Wei Xu, Qiaoshuai Lan, Siliang Feng, Feifei Qi, Linlin Bao, Lanying Du, Shuwen Liu, Chuan Qin, Fei Sun, Zhengli Shi, Yun Zhu, Shibo Jiang, Lu Lu
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell research 30 (4) (2020)
Suiyi Tan, Wenjuan Li, Zhaofeng Li, Yujing Li, Jiangyan Luo, Liangzhentian Yu, Jie Yang, Mengjie Qiu, Hongyan Cheng, Wei Xu, Shibo Jiang, Lu Lu, Shu-Wen Liu, Weifeng Ma
A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor. Viruses 11 (9) (2019)
Wenwen Bi, Wei Xu, Liang Cheng, Jing Xue, Qian Wang, Fei Yu, Shuai Xia, Qi Wang, Guangming Li, Chuan Qin, Lu Lu, Lishan Su, Shibo Jiang
IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies. PLoS pathogens 15 (12) (2019)
Shan Su, Giselle Rasquinha, Lanying Du, Qian Wang, Wei Xu, Weihua Li, Lu Lu, Shibo Jiang
A Peptide-Based HIV-1 Fusion Inhibitor with Two Tail-Anchors and Palmitic Acid Exhibits Substantially Improved In Vitro and Ex Vivo Anti-HIV-1 Activity and Prolonged In Vivo Half-Life. Molecules (Basel, Switzerland) 24 (6) (2019)
Xiaohuan Wang, Shuai Xia, Peng Zou, Lu Lu
Erythromycin Estolate Inhibits Zika Virus Infection by Blocking Viral Entry as a Viral Inactivator. Viruses 11 (11) (2019)
Shuai Xia, Qiaoshuai Lan, Jing Pu, Cong Wang, Zezhong Liu, Wei Xu, Qian Wang, Huan Liu, Shibo Jiang, Lu Lu
Potent MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein of Bat Coronavirus HKU4. Viruses 11 (1) (2019)
Shuai Xia, Lei Yan, Wei Xu, Anurodh Shankar Agrawal, Abdullah Algaissi, Chien-Te K Tseng, Qian Wang, Lanying Du, Wenjie Tan, Ian A Wilson, Shibo Jiang, Bei Yang, Lu Lu
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science advances 5 (4) (2019)

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