Luke Boulter (L Boulter)

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 22

Top Topics

Dna Damage Response

Signaling Pathway

Top Venues

Science translational medicine

Nature communications

Nature reviews. Gastroenterology & hepatology

Expert opinion on investigational drugs

This page only lists publications with an associated author ORCID identifier.

Publications

Colm J O'Rourke, Massimiliano Salati, Colin Rae, Carpino Guido, Holly Leslie, Antonio Pea, Maria G Prete, Luca R Bonetti, Francesco Amato, Robert Montal, Rosie Upstill-Goddard, Colin Nixon, Paula Sanchon-Sanchez, Paolo Kunderfranco, Daniela Sia, Eugenio Gaudio, Diletta Overi, Stefano Cascinu, Dan Hogdall, Sian Pugh, Enric Domingo, John N Primrose, John Bridgewater, Andrea Spallanzani, Fabio Gelsomino, Josep M Llovet, Diego F Calvisi, Luke Boulter, Francesco Caputo, Ana Lleo, Nigel B Jamieson, Gabriele Luppi, Massimo Dominici, Jesper B Andersen, Chiara Braconi
Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy. Gut (2023)
Diego F Calvisi, Luke Boulter, Javier Vaquero, Anna Saborowski, Luca Fabris, Pedro M Rodrigues, Cédric Coulouarn, Rui E Castro, Oreste Segatto, Chiara Raggi, Luc J W van der Laan, Carpino Guido, Benjamin Goeppert, Stephanie Roessler, Timothy James Kendall, Matthias Evert, Ester Gonzalez-Sanchez, Juan W Valle, Arndt Vogel, John A Bridgewater, Mitesh J Borad, Gregory J Gores, Lewis Rowland Roberts, Jose J G Marin, Jesper B Andersen, Domenico Alvaro, Alejandro Forner, Jesus Maria Banales, Vincenzo Cardinale, Rocío I R Macías, Silvestre Vincent, Xin Chen, Chiara Braconi, Monique M A Verstegen, Laura Fouassier, null null
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance. Nature reviews. Gastroenterology & hepatology (2023)
Scott H Waddell, Yuelin Yao, Paula Olaizola, Alexander Walker, Edward J Jarman, Konstantinos Gournopanos, Andreea Gradinaru, Ersi Christodoulou, Philippe Gautier, Melissa M Boerrigter, Massimiliano Cadamuro, Luca Fabris, Joost Paulus Hubertus Drenth, Timothy James Kendall, Jesus M Banales, Ava Khamseh, Pleasantine Mill, Luke Boulter
A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease. Science translational medicine 15 (713) (2023)
Diego F Calvisi, Luke Boulter, Javier Vaquero, Anna Saborowski, Luca Fabris, Pedro M Rodrigues, Cédric Coulouarn, Rui E Castro, Oreste Segatto, Chiara Raggi, Luc J W van der Laan, Carpino Guido, Benjamin Goeppert, Stephanie Roessler, Timothy James Kendall, Matthias Evert, Ester Gonzalez-Sanchez, Juan W Valle, Arndt Vogel, John A Bridgewater, Mitesh J Borad, Gregory J Gores, Lewis Rowland Roberts, Jose J G Marin, Jesper B Andersen, Domenico Alvaro, Alejandro Forner, Jesus Maria Banales, Vincenzo Cardinale, Rocío I R Macías, Silvestre Vincent, Xin Chen, Chiara Braconi, Monique M A Verstegen, Laura Fouassier, null null
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance. Nature reviews. Gastroenterology & hepatology (2023)
Anabel Martinez Lyons, Luke Boulter
NOTCH signalling - a core regulator of bile duct disease? Disease models & mechanisms 16 (9) (2023)
Eoin Daniel O'Sullivan, Katie J Mylonas, Cuiyan Xin, David P Baird, Cyril Carvalho, Marie-Helena Docherty, Ross Campbell, Kylie P Matchett, Scott H Waddell, Alexander D Walker, Kevin Michael Gallagher, Siyang Jia, Steve Leung, Alexander Laird, Julia Wilflingseder, Michaela Willi, Maximilian Reck, Sarah Finnie, Angela Oliveira Pisco, Sabrina Gordon-Keylock, Alexander Medvinsky, Luke Boulter, Neil Cowan Henderson, Kristina Kirschner, Tamir Chandra, Bryan R Conway, Jeremy Hughes, Laura Denby, Joseph V Bonventre, David A Ferenbach
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis. Science translational medicine 15 (698) (2023)
Sofía Ferreira-González, Tak Yung Man, Hannah Esser, Rhona Aird, Alastair M Kilpatrick, Daniel Rodrigo-Torres, Nicholas T Younger, Lara Campana, Victoria L Gadd, Benjamin J Dwyer, Niya Aleksieva, Luke Boulter, Mark T Macmillan, Yinmiao Wang, Katie J Mylonas, David A Ferenbach, Timothy James Kendall, Wei-Yu Lu, Juan Carlos Acosta, Dominic Kurian, Stephen O'Neill, Gabriel C Oniscu, Jesus M Banales, Paul J Krimpenfort, Stuart John Forbes
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage. Science translational medicine 14 (674) (2022)
Edward J Jarman, Marta Horcas-Lopez, Scott H Waddell, Stephanie MacMaster, Konstantinos Gournopanos, Daniel Y H Soong, Kamila I Musialik, Panagiota Tsokkou, Minn-E Ng, William A Cambridge, David H Wilson, Michael H Kagey, Walter Newman, Jeffery W Pollard, Luke Boulter
DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01. Liver international : official journal of the International Association for the Study of the Liver (2022)
Nicholas T Younger, Mollie L Wilson, Anabel Martinez Lyons, Edward J Jarman, Alison M Meynert, Graeme R Grimes, Konstantinos Gournopanos, Scott H Waddell, Peter A Tennant, David H Wilson, Rachel V Guest, Stephen J Wigmore, Juan Carlos Acosta, Timothy James Kendall, Martin S Taylor, Duncan Sproul, Pleasantine Mill, Luke Boulter
In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma. Cancer research 82 (8) (2022)
Anabel Martinez Lyons, Luke Boulter
The developmental origins of Notch-driven intrahepatic bile duct disorders. Disease models & mechanisms 14 (9) (2021)
Scott H Waddell, Luke Boulter
Developing models of cholangiocarcinoma to close the translational gap in cancer research. Expert opinion on investigational drugs 30 (4) (2021)
Sarah E Minnis-Lyons, Sofía Ferreira-González, Niya Aleksieva, Tak Yung Man, Victoria L Gadd, Michael J Williams, Rachel V Guest, Wei-Yu Lu, Benjamin J Dwyer, Thomas Jamieson, Colin Nixon, Noémi K M van Hul, Frederic P Lemaigre, John McCafferty, Isabelle A Leclercq, Owen James Sansom, Luke Boulter, Stuart John Forbes
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation. Science signaling 14 (688) (2021)
Edward J Jarman, Luke Boulter
Targeting the Wnt signaling pathway: the challenge of reducing scarring without affecting repair. Expert opinion on investigational drugs 29 (2) (2020)
Jesus Maria Banales, Jose J G Marin, Angela Lamarca, Pedro M Rodrigues, Shahid A Khan, Lewis Rowland Roberts, Vincenzo Cardinale, Carpino Guido, Jesper B Andersen, Chiara Braconi, Diego F Calvisi, Maria J Perugorria, Luca Fabris, Luke Boulter, Rocío I R Macías, Eugenio Gaudio, Domenico Alvaro, Sergio A Gradilone, Mario Strazzabosco, Marco Marzioni, Cédric Coulouarn, Laura Fouassier, Chiara Raggi, Invernizzi Pietro, Joachim C Mertens, Anja Moncsek, Sumera Rizvi, Julie Heimbach, Bas Groot Koerkamp, Jordi Bruix, Alejandro Forner, John A Bridgewater, Juan W Valle, Gregory J Gores
Cholangiocarcinoma 2020: the next horizon in mechanisms and management. Nature reviews. Gastroenterology & hepatology 17 (9) (2020)
David H Wilson, Edward J Jarman, Ronan Mellin, M L Wilson, S H Waddell, P Tsokkou, Nicholas T Younger, A Raven, S R Bhalla, A T R Noll, S W Olde Damink, F G Schaap, P Chen, D O Bates, J M Banales, Charlotte H Dean, D J Henderson, Owen James Sansom, Timothy James Kendall, Luke Boulter
Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors. Nature communications 11 (1) (2020)
Timothy James Kendall, Catherine Mary Duff, Luke Boulter, David H Wilson, Elisabeth Freyer, Stuart Aitken, Stuart John Forbes, John Peter Iredale, Nicholas Dixon Hastie
Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1. Nature communications 10 (1) (2019)
Thomas G Bird, Miryam Müller, Luke Boulter, David F Vincent, Rachel A Ridgway, Elena Lopez-Guadamillas, Wei-Yu Lu, Thomas Jamieson, Olivier Govaere, Andrew D Campbell, Sofía Ferreira-González, Alicia M Cole, Trevor Hay, Kenneth J Simpson, William Clark, Ann Hedley, Mairi Clarke, Pauline Gentaz, Colin Nixon, Steven Bryce, Christos Kiourtis, Joep Sprangers, Robert J B Nibbs, Nico Van Rooijen, Laurent Bartholin, Steven R McGreal, Udayan Apte, Simon T Barry, John P Iredale, Alan R Clarke, Manuel Serrano, Tania A Roskams, Owen James Sansom, Stuart John Forbes
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science translational medicine 10 (454) (2019)
Priya Hari, Fraser R Millar, Núria Tarrats, Jodie Birch, Andrea Quintanilla, Curtis J Rink, Irene Fernández-Duran, Morwenna T Muir, Andrew J Finch, Valerie G Brunton, João F Passos, Jennifer P Morton, Luke Boulter, Juan Carlos Acosta
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Science advances 5 (6) (2019)
Sofia Ferreira-Gonzalez, Wei-Yu Lu, Alexander Raven, Benjamin Dwyer, Tak Yung Man, Eoghan O'Duibhir, Philip J Starkey Lewis, Lara Campana, Timothy James Kendall, Thomas G Bird, Nuria Tarrats, Juan Carlos Acosta, Luke Boulter, Stuart J Forbes
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration. Nature communications 9 (1) (2018)
Lara Campana, Philip J Starkey Lewis, Antonella Pellicoro, Rebecca L Aucott, Janet Man, Eoghan O'Duibhir, Sarah E Mok, Sofia Ferreira-Gonzalez, Eilidh Livingstone, Stephen N Greenhalgh, Katherine Leigh Hull, Timothy James Kendall, Douglas Vernimmen, Neil C Henderson, Luke Boulter, Christopher D Gregory, Yi Feng, Stephen M Anderton, Stuart J Forbes, John P Iredale
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury. Journal of immunology (Baltimore, Md. : 1950) 200 (3) (2017)
Lara Planas-Paz, Vanessa Orsini, Luke Boulter, Diego Calabrese, Monika Pikiolek, Florian Nigsch, Yang Xie, Guglielmo Roma, Adriana Donovan, Patricia Marti, Nicolau Beckmann, Michael T Dill, Walter Carbone, Sebastian Bergling, Andrea Isken, Matthias Mueller, Bernd Kinzel, Yi Yang, Xiaohong Mao, Thomas B Nicholson, Raffaella Zamponi, Paola Capodieci, Reginald Valdez, Daniel Rivera, Andreas Loew, Chinweike Ukomadu, Luigi M Terracciano, Tewis Bouwmeester, Feng Cong, Markus H Heim, Stuart J Forbes, Heinz Ruffner, Jan S Tchorz
The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size. Nature cell biology 18 (5) (2016)
Rachel V Guest, Luke Boulter, Benjamin J Dwyer, Timothy J Kendall, Tak-Yung Man, Sarah E Minnis-Lyons, Wei-Yu Lu, Andrew J Robson, Sofia Ferreira Gonzalez, Alexander Raven, Davina Wojtacha, Jennifer P Morton, Mina Komuta, Tania Roskams, Stephen J Wigmore, Owen J Sansom, Stuart J Forbes
Notch3 drives development and progression of cholangiocarcinoma. Proceedings of the National Academy of Sciences of the United States of America 113 (43) (2016)