Manuel Serrano (M Serrano)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 61

Top Venues

Nature communications

Nature cancer

Nature metabolism

Nature neuroscience

Institute for Research in Biomedicine (IRB Barcelona)

Universidad Autonoma de Madrid (UAM) - Biology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute for Research in Biomedicine (IRB Barcelona) May 01 2017

Spain

Group Leader :: Cellular Plasticity and Disease Group

Spanish National Cancer Research Centre (CNIO) - Apr 30 2017

Spain

Director :: Molecular Oncology Programme

Spanish National Cancer Research Centre (CNIO) - Apr 30 2017

Spain

Head :: Tumour Suppression Group

Spanish National Centre of Biotechnology (CNB)

Spain

Investigador Científico CSIC :: Dept. of Immunology and Oncology

Spanish National Centre of Biotechnology (CNB) Jan 01 1997 - Dec 31 2001

Spain

Cientifico Titular CSIC :: Dept. of Immunology and Oncology

Cold Spring Harbor Laboratory (CSHL) Jan 01 1992 - Dec 31 1996

United States

Postdoctoral Fellow :: David Beach's Lab

Centre of Molecular Biology "Severo Ochoa" (CBMSO) Jan 31 1987 - Dec 31 1991

Spain

Predoctoral Fellow :: Margarita Salas' Lab

Education History

Universidad Autonoma de Madrid (UAM) - Biology

Spain

PHD :: Dept. of Biochemistry and Molecular Biology

Universidad Autónoma de Madrid (UAM) - Biology

Spain

BSC :: Biology

Publications

Vanessa López-Polo, Mate Maus, Emmanouil Zacharioudakis, Miguel Lafarga, Camille Stephan-Otto Attolini, Francisco D M Marques, Marta Kovatcheva, Evripidis Gavathiotis, Manuel Serrano
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells. Nature communications 15 (1) (2024)
Martin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, Delany Rodriguez, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Brian Kirk, Aaron Havas, Gen-Sheng Feng, Amanda J Roberts, Rozalyn M Anderson, Manuel Serrano, Peter D Adams, Tatyana O Sharpee, Alexey V Terskikh
ImAge quantitates aging and rejuvenation. Nature aging (2024)
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, Shangli Cheng, Eosu Kim, Benjamin U Phillips, Christopher J Heath, Richa B Tripathi, Cody L Call, Theresa Bartels, Katherine Ridley, Björn Neumann, Laura López-Cruz, Abbe H Crawford, Cian J Lynch, Manuel Serrano, Lisa Saksida, David H Rowitch, Wiebke Möbius, Klaus-Armin Nave, Matthew N Rasband, Dwight E Bergles, Nicoletta Kessaris, William D Richardson, Timothy J Bussey, Chao Zhao, Gonçalo Castelo-Branco, Robin J M Franklin
Developmental origin of oligodendrocytes determines their function in the adult brain. Nature neuroscience (2024)
Fernanda Hernandez-Gonzalez, Federico Pietrocola, Paolo Cameli, Elena Bargagli, Sergio Prieto-González, Tamara Cruz, Nuria Mendoza, Mauricio Rojas, Manuel Serrano, Alvar Agustí, Rosa Faner, José A Gómez-Puerta, Jacobo Sellarés
Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and Opportunities. International journal of molecular sciences 25 (14) (2024)
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, Shangli Cheng, Eosu Kim, Benjamin U Phillips, Christopher J Heath, Richa B Tripathi, Cody L Call, Theresa Bartels, Katherine Ridley, Björn Neumann, Laura López-Cruz, Abbe H Crawford, Cian J Lynch, Manuel Serrano, Lisa Saksida, David H Rowitch, Wiebke Möbius, Klaus-Armin Nave, Matthew N Rasband, Dwight E Bergles, Nicoletta Kessaris, William D Richardson, Timothy J Bussey, Chao Zhao, Gonçalo Castelo-Branco, Robin J M Franklin
Developmental origin of oligodendrocytes determines their function in the adult brain. Nature neuroscience 27 (8) (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer 5 (3) (2024)
Josep Amengual, Ania Alay, Javier Vaquero, Ester Gonzalez-Sanchez, Esther Bertran, Aránzazu Sánchez, Blanca Herrera, Kathleen Meyer, Mate Maus, Manuel Serrano, María Luz Martínez-Chantar, Isabel Fabregat
Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression. Cell death & disease 15 (9) (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer 5 (3) (2024)
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, Shangli Cheng, Eosu Kim, Benjamin U Phillips, Christopher J Heath, Richa B Tripathi, Cody L Call, Theresa Bartels, Katherine Ridley, Björn Neumann, Laura López-Cruz, Abbe H Crawford, Cian J Lynch, Manuel Serrano, Lisa Saksida, David H Rowitch, Wiebke Möbius, Klaus-Armin Nave, Matthew N Rasband, Dwight E Bergles, Nicoletta Kessaris, William D Richardson, Timothy J Bussey, Chao Zhao, Gonçalo Castelo-Branco, Robin J M Franklin
Developmental origin of oligodendrocytes determines their function in the adult brain. Nature neuroscience 27 (8) (2024)
Martin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, Delany Rodriguez, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Brian Kirk, Aaron Havas, Gen-Sheng Feng, Amanda J Roberts, Rozalyn M Anderson, Manuel Serrano, Peter D Adams, Tatyana O Sharpee, Alexey V Terskikh
ImAge quantitates aging and rejuvenation. Nature aging (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer (2024)
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, Shangli Cheng, Eosu Kim, Benjamin U Phillips, Christopher J Heath, Richa B Tripathi, Cody L Call, Theresa Bartels, Katherine Ridley, Björn Neumann, Laura López-Cruz, Abbe H Crawford, Cian J Lynch, Manuel Serrano, Lisa Saksida, David H Rowitch, Wiebke Möbius, Klaus-Armin Nave, Matthew N Rasband, Dwight E Bergles, Nicoletta Kessaris, William D Richardson, Timothy J Bussey, Chao Zhao, Gonçalo Castelo-Branco, Robin J M Franklin
Developmental origin of oligodendrocytes determines their function in the adult brain. Nature neuroscience 27 (8) (2024)
Sarah Foerster, Elisa M Floriddia, David van Bruggen, Petra Kukanja, Bastien Hervé, Shangli Cheng, Eosu Kim, Benjamin U Phillips, Christopher J Heath, Richa B Tripathi, Cody L Call, Theresa Bartels, Katherine Ridley, Björn Neumann, Laura López-Cruz, Abbe H Crawford, Cian J Lynch, Manuel Serrano, Lisa Saksida, David H Rowitch, Wiebke Möbius, Klaus-Armin Nave, Matthew N Rasband, Dwight E Bergles, Nicoletta Kessaris, William D Richardson, Timothy J Bussey, Chao Zhao, Gonçalo Castelo-Branco, Robin J M Franklin
Developmental origin of oligodendrocytes determines their function in the adult brain. Nature neuroscience 27 (8) (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer 5 (3) (2024)
Fernanda Hernandez-Gonzalez, Federico Pietrocola, Paolo Cameli, Elena Bargagli, Sergio Prieto-González, Tamara Cruz, Nuria Mendoza, Mauricio Rojas, Manuel Serrano, Alvar Agustí, Rosa Faner, José A Gómez-Puerta, Jacobo Sellarés
Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and Opportunities. International journal of molecular sciences 25 (14) (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer 5 (3) (2024)
Fernanda Hernandez-Gonzalez, Federico Pietrocola, Paolo Cameli, Elena Bargagli, Sergio Prieto-González, Tamara Cruz, Nuria Mendoza, Mauricio Rojas, Manuel Serrano, Alvar Agustí, Rosa Faner, José A Gómez-Puerta, Jacobo Sellarés
Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and Opportunities. International journal of molecular sciences 25 (14) (2024)
Vanessa López-Polo, Mate Maus, Emmanouil Zacharioudakis, Miguel Lafarga, Camille Stephan-Otto Attolini, Francisco D M Marques, Marta Kovatcheva, Evripidis Gavathiotis, Manuel Serrano
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells. Nature communications 15 (1) (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer (2024)
Selim Chaib, José Alberto López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Ines Marin, Olga Boix, Andrea García-Garijo, Kathleen Meyer, María Isabel Muñoz, Mònica Aguilera, Lidia Mateo, Camille Stephan-Otto Attolini, Susana Llanos, Sandra Pérez-Ramos, Marta Escorihuela, Fátima Al-Shahrour, Timothy P Cash, Tamara Tchkonia, James L Kirkland, María Abad, Alena Gros, Joaquín Arribas, Manuel Serrano
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2. Nature cancer (2024)
Margherita Protasoni, Manuel Serrano
Targeting Mitochondria to Control Ageing and Senescence. Pharmaceutics 15 (2) (2023)
Domhnall McHugh, Bin Sun, Carmen Gutierrez-Muñoz, Fernanda Hernández-González, Massimiliano Mellone, Romain Guiho, Imanol Duran, Joaquim Pombo, Federico Pietrocola, Jodie Birch, Wouter W Kallemeijn, Sanjay Khadayate, Gopuraja Dharmalingam, Santiago Vernia, Edward William Tate, Juan Pedro Martínez-Barbera, Dominic J Withers, Gareth J Thomas, Manuel Serrano, Jesús Gil
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells. Nature cell biology (2023)
Ines Marin, Manuel Serrano, Federico Pietrocola
Recent insights into the crosstalk between senescent cells and CD8 T lymphocytes. npj aging 9 (1) (2023)
Margherita Protasoni, Manuel Serrano
Targeting Mitochondria to Control Ageing and Senescence. Pharmaceutics 15 (2) (2023)
Mate Maus, Vanessa López-Polo, Lidia Mateo, Miguel Lafarga, Mònica Aguilera, Eugenia De Lama, Kathleen Meyer, Dolors Serra, Cecilia Lopez-Martinez, Ines López-Alonso, Marc Guasch-Piqueras, Fernanda Hernandez-Gonzalez, Selim Chaib, Miguel Rovira, Mayka Sanchez, Rosa Faner, Alvar Agustí, Rodrigo Diéguez-Hurtado, Sagrario Ortega, Anna Manonelles, Stefan Engelhardt, Freddy Monteiro, Camille Stephan-Otto Attolini, Neus Prats, Guillermo M Albaiceta, Josep M Cruzado, Manuel Serrano
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Nature metabolism 5 (12) (2023)
Alexey Terskikh, Martin Alvarez-Kuglen, Delany Rodriguez, Haodong Qin, Kenta Ninomiya, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Aaron Havas, Gen-Sheng Feng, Amanda Roberts, Rozalyn M Anderson, Manuel Serrano, Peter D Adams, Tatyana Sharpee
Imaging-based chromatin and epigenetic age, ImAge, quantitates aging and rejuvenation. Research square (2023)
Margherita Protasoni, Manuel Serrano
Targeting Mitochondria to Control Ageing and Senescence. Pharmaceutics 15 (2) (2023)
Mate Maus, Vanessa López-Polo, Lidia Mateo, Miguel Lafarga, Mònica Aguilera, Eugenia De Lama, Kathleen Meyer, Dolors Serra, Cecilia Lopez-Martinez, Ines López-Alonso, Marc Guasch-Piqueras, Fernanda Hernandez-Gonzalez, Selim Chaib, Miguel Rovira, Mayka Sanchez, Rosa Faner, Alvar Agustí, Rodrigo Diéguez-Hurtado, Sagrario Ortega, Anna Manonelles, Stefan Engelhardt, Freddy Monteiro, Camille Stephan-Otto Attolini, Neus Prats, Guillermo M Albaiceta, Josep M Cruzado, Manuel Serrano
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Nature metabolism (2023)
Mate Maus, Vanessa López-Polo, Lidia Mateo, Miguel Lafarga, Mònica Aguilera, Eugenia De Lama, Kathleen Meyer, Dolors Serra, Cecilia Lopez-Martinez, Ines López-Alonso, Marc Guasch-Piqueras, Fernanda Hernandez-Gonzalez, Selim Chaib, Miguel Rovira, Mayka Sanchez, Rosa Faner, Alvar Agustí, Rodrigo Diéguez-Hurtado, Sagrario Ortega, Anna Manonelles, Stefan Engelhardt, Freddy Monteiro, Camille Stephan-Otto Attolini, Neus Prats, Guillermo M Albaiceta, Josep M Cruzado, Manuel Serrano
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Nature metabolism 5 (12) (2023)
Mate Maus, Vanessa López-Polo, Lidia Mateo, Miguel Lafarga, Mònica Aguilera, Eugenia De Lama, Kathleen Meyer, Dolors Serra, Cecilia Lopez-Martinez, Ines López-Alonso, Marc Guasch-Piqueras, Fernanda Hernandez-Gonzalez, Selim Chaib, Miguel Rovira, Mayka Sanchez, Rosa Faner, Alvar Agustí, Rodrigo Diéguez-Hurtado, Sagrario Ortega, Anna Manonelles, Stefan Engelhardt, Freddy Monteiro, Camille Stephan-Otto Attolini, Neus Prats, Guillermo M Albaiceta, Josep M Cruzado, Manuel Serrano
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Nature metabolism 5 (12) (2023)
Marta Kovatcheva, Elena Melendez, Dafni Chondronasiou, Federico Pietrocola, Raquel Bernad, Adrià Caballé, Alexandra Junza, Jordi Capellades, Adrián Holguín-Horcajo, Neus Prats, Sylvere Durand, Meritxell Rovira, Óscar Yanes, Camille Stephan-Otto Attolini, Guido Kroemer, Manuel Serrano
Vitamin B 12 is a limiting factor for induced cellular plasticity and tissue repair. Nature metabolism (2023)
Mate Maus, Vanessa López-Polo, Lidia Mateo, Miguel Lafarga, Mònica Aguilera, Eugenia De Lama, Kathleen Meyer, Dolors Serra, Cecilia Lopez-Martinez, Ines López-Alonso, Marc Guasch-Piqueras, Fernanda Hernandez-Gonzalez, Selim Chaib, Miguel Rovira, Mayka Sanchez, Rosa Faner, Alvar Agustí, Rodrigo Diéguez-Hurtado, Sagrario Ortega, Anna Manonelles, Stefan Engelhardt, Freddy Monteiro, Camille Stephan-Otto Attolini, Neus Prats, Guillermo M Albaiceta, Josep M Cruzado, Manuel Serrano
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Nature metabolism 5 (12) (2023)
Ines Marin, Manuel Serrano, Federico Pietrocola
Cellular senescence enhances adaptive anticancer immunosurveillance. Oncoimmunology 12 (1) (2022)
Elena Melendez, Dafni Chondronasiou, Lluc Mosteiro, Jaime Martínez de Villarreal, Marcos Fernández-Alfara, Cian J Lynch, Dirk Grimm, Francisco X Real, José Alcamí, Núria Climent, Federico Pietrocola, Manuel Serrano
Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development (Cambridge, England) 149 (8) (2022)
Ines Marin, Manuel Serrano, Federico Pietrocola
Cellular senescence enhances adaptive anticancer immunosurveillance. Oncoimmunology 12 (1) (2022)
Ines Marin, Manuel Serrano, Federico Pietrocola
Cellular senescence enhances adaptive anticancer immunosurveillance. Oncoimmunology 12 (1) (2022)
Dafni Chondronasiou, Diljeet Gill, Lluc Mosteiro, Rocio G Urdinguio, Antoni Berenguer Llergo, Mònica Aguilera, Sylvere Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, María Abad, Daniel E Martin-Herranz, Camille Stephan-Otto Attolini, Neus Prats, Guido Kroemer, Mario Fernández Fraga, Juan I Garaycoechea, Manuel Serrano
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming. Aging cell 21 (3) (2022)
Ines Marin, Manuel Serrano, Federico Pietrocola
Cellular senescence enhances adaptive anticancer immunosurveillance. Oncoimmunology 12 (1) (2022)
Estefania Carrasco-Garcia, Lidia Lopez, Veronica Moncho-Amor, Fernando Carazo, Paula Aldaz, Manuel Collado, Donald M Bell, Ayman Gaafar, Eva Karamitopoulou, Alexandar Tzankov, Manuel Hidalgo, Ángel Rubio, Manuel Serrano, Charles Henderson Lawrie, Robin Lovell-Badge, Ander Matheu
SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression. Cancers 14 (4) (2022)
Miguel Rovira, Rebecca Sereda, David Pladevall-Morera, Valentina Ramponi, Ines Marin, Mate Maus, Julio Madrigal-Matute, Antonio Diaz, Fernando Garcίa, Javier Munoz, Ana Maria Cuervo, Manuel Serrano
The lysosomal proteome of senescent cells contributes to the senescence secretome. Aging cell 21 (10) (2022)
Cian J Lynch, Manuel Serrano
Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it. Molecular systems biology 18 (9) (2022)
Marta Barradas, Adrián Plaza, Gonzalo Colmenarejo, Iolanda Lázaro, Luis Filipe Costa-Machado, Roberto Martín-Hernández, Victor Micó, José Luis López-Aceituno, Jesús Herranz, Cristina Pantoja, Hector Tejero, Alberto Díaz-Ruiz, Fátima Al-Shahrour, Lidia Daimiel Ruiz, Viviana Loria-Kohen, Ana Ramírez de Molina, Alejo Efeyan, Manuel Serrano, Oscar J Pozo, Aleix Sala-Vila, Pablo Jose Fernandez-Marcos
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity. Nature communications 13 (1) (2022)
Ines Marin, Olga Boix, Andrea García-Garijo, Isabelle Sirois, Adrià Caballé, Eduardo Zarzuela, Irene Ruano, Camille Stephan-Otto Attolini, Neus Prats, José Alberto López-Domínguez, Marta Kovatcheva, Elena Garralda, Javier Munoz, Etienne Caron, María Abad, Alena Gros, Federico Pietrocola, Manuel Serrano
Cellular senescence is immunogenic and promotes anti-tumor immunity. Cancer discovery (2022)
Cristina Batlle, Isabel Calvo, Valentin Iglesias, Cian J Lynch, Marcos Gil-Garcia, Manuel Serrano, Salvador Ventura
MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation. Communications biology 4 (1) (2021)
Fernanda Hernandez-Gonzalez, Rosa Faner, Mauricio Rojas, Alvar Agustí, Manuel Serrano, Jacobo Sellarés
Cellular Senescence in Lung Fibrosis. International journal of molecular sciences 22 (13) (2021)
Jose M Bermúdez-Muñoz, Adelaida M Celaya, Ángela García-Mato, Daniel Muñoz-Espín, Lourdes Rodríguez-de la Rosa, Manuel Serrano, Isabel Varela-Nieto
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea. Antioxidants (Basel, Switzerland) 10 (9) (2021)
Ana Martínez-Val, Cian J Lynch, Isabel Calvo, Pilar Ximénez-Embún, Fernando Garcia, Eduardo Zarzuela, Manuel Serrano, Javier Munoz
Dissection of two routes to naïve pluripotency using different kinase inhibitors. Nature communications 12 (1) (2021)
Asael Roichman, S Elhanati, M A Aon, I Abramovich, A Di Francesco, Y Shahar, M Y Avivi, M Shurgi, A Rubinstein, Y Wiesner, Adi Shuchami, Z Petrover, I Lebenthal-Loinger, O Yaron, A Lyashkov, C Ubaida-Mohien, Y Kanfi, B Lerrer, Pablo Jose Fernandez-Marcos, Manuel Serrano, Eyal Gottlieb, Rafael de Cabo, H Y Cohen
Restoration of energy homeostasis by SIRT6 extends healthy lifespan. Nature communications 12 (1) (2021)
Raquel Bernad, Cian J Lynch, Rocio G Urdinguio, Camille Stephan-Otto Attolini, Mario F Fraga, Manuel Serrano
Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19. Cells 10 (4) (2021)
Cian J Lynch, Raquel Bernad, Ana Martínez-Val, Marta N Shahbazi, Sandrina Nóbrega-Pereira, Isabel Calvo, Carmen Blanco-Aparicio, Carolina Tarantino, Elena Garreta, Laia Richart-Ginés, Noelia Alcazar, Osvaldo Graña-Castro, Gonzalo Gómez-López, Irene Aksoy, Maribel Muñoz-Martín, Sonia Martínez-González, Sagrario Ortega, Susana Prieto, Elisabeth Simboeck, Alain Camasses, Camille Stephan-Otto Attolini, Agustín Fernández Fernández, Marta I Sierra, Mario F Fraga, Joaquin Pastor, Daniel Fisher, Nuria Montserrat, Pierre Savatier, Javier Munoz, Magdalena Zernicka Goetz, Manuel Serrano
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases. Nature cell biology 22 (10) (2020)
Timothy P Cash, Sonia Alcalá, María Del Rosario Rico-Ferreira, Elena Hernández-Encinas, Jennifer García, María Isabel Albarrán, Sandra Valle, Javier Muñoz, Sonia Martínez-González, Carmen Blanco-Aparicio, Joaquín Pastor, Manuel Serrano, Bruno Sainz
Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells. Cancers 12 (7) (2020)
Jose M Bermúdez-Muñoz, Adelaida M Celaya, Sara Hijazo-Pechero, Jing Wang, Manuel Serrano, Isabel Varela-Nieto
G6PD overexpression protects from oxidative stress and age-related hearing loss. Aging cell 19 (12) (2020)
Mark C Wilkes, Kavitha Siva, J Chen, G Varetti, M Y Youn, H Chae, Fredrik Ek, Roger Olsson, T Lundbäck, Daniel P Dever, Toshinobu Nishimura, A Narla, B Glader, Hiromitsu Nakauchi, Matthew H Porteus, C E Repellin, H T Gazda, S Lin, Manuel Serrano, Johan Flygare, K M Sakamoto
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nature communications 11 (1) (2020)
María Salazar-Roa, Marianna Trakala, Mónica Álvarez-Fernández, Fatima Valdes Mora, Cuiqing Zhong, Jaime Muñoz, Yang Yu, Timothy J Peters, Osvaldo Graña-Castro, Rosa Serrano, Elisabet Zapatero-Solana, María Abad, María José Bueno, Marta Gómez de Cedrón, José Fernández-Piqueras, Manuel Serrano, Maria A Blasco, Da-Zhi Wang, Susan J Clark, Juan Carlos Izpisua-Belmonte, Sagrario Ortega, Marcos Malumbres
Transient exposure to miR-203 enhances the differentiation capacity of established pluripotent stem cells. The EMBO journal 39 (16) (2020)
Francisco Triana-Martínez, Pilar Picallos-Rabina, Sabela Da Silva-Álvarez, Federico Pietrocola, Susana Llanos, Veronica Rodilla, Enrica Soprano, Pablo Pedrosa, Alba Ferreirós, Marta Barradas, Fernanda Hernández-González, Marta Lalinde, Neus Prats, Cristina Bernadó, Patricia González, María Gómez, Maria P Ikonomopoulou, Pablo Jose Fernandez-Marcos, Tomás García-Caballero, Pablo Del Pino, Joaquín Arribas, Anxo Vidal, Miguel González-Barcia, Manuel Serrano, María I Loza, Eduardo Domínguez, Manuel Collado
Author Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds. Nature communications 11 (1) (2020)
Susana Llanos, Diego Megias, Carmen Blanco-Aparicio, Elena Hernández-Encinas, Miguel Rovira, Federico Pietrocola, Manuel Serrano
Lysosomal trapping of palbociclib and its functional implications. Oncogene 38 (20) (2019)
Daniel Muñoz-Espín, Miguel Rovira, Irene Galiana, Cristina Giménez, Beatriz Lozano-Torres, Marta Paez-Ribes, Susana Llanos, Selim Chaib, Maribel Muñoz-Martín, Alvaro C Ucero, Guillermo Garaulet, Francisca Mulero, Stephen G Dann, Todd VanArsdale, David J Shields, Andrea Bernardos, José Ramón Murguía, Ramón Martínez-Máñez, Manuel Serrano
A versatile drug delivery system targeting senescent cells. EMBO molecular medicine 10 (9) (2019)
Francisco Triana-Martínez, Pilar Picallos-Rabina, Sabela Da Silva-Álvarez, Federico Pietrocola, Susana Llanos, Veronica Rodilla, Enrica Soprano, Pablo Pedrosa, Alba Ferreirós, Marta Barradas, Fernanda Hernández-González, Marta Lalinde, Neus Prats, Cristina Bernadó, Patricia González, María Gómez, Maria P Ikonomopoulou, Pablo Jose Fernandez-Marcos, Tomás García-Caballero, Pablo Del Pino, Joaquín Arribas, Anxo Vidal, Miguel González-Barcia, Manuel Serrano, María I Loza, Eduardo Domínguez, Manuel Collado
Identification and characterization of Cardiac Glycosides as senolytic compounds. Nature communications 10 (1) (2019)
Thomas G Bird, Miryam Müller, Luke Boulter, David F Vincent, Rachel A Ridgway, Elena Lopez-Guadamillas, Wei-Yu Lu, Thomas Jamieson, Olivier Govaere, Andrew D Campbell, Sofía Ferreira-González, Alicia M Cole, Trevor Hay, Kenneth J Simpson, William Clark, Ann Hedley, Mairi Clarke, Pauline Gentaz, Colin Nixon, Steven Bryce, Christos Kiourtis, Joep Sprangers, Robert J B Nibbs, Nico Van Rooijen, Laurent Bartholin, Steven R McGreal, Udayan Apte, Simon T Barry, John P Iredale, Alan R Clarke, Manuel Serrano, Tania A Roskams, Owen James Sansom, Stuart John Forbes
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science translational medicine 10 (454) (2019)
Luis Filipe Costa-Machado, Roberto Martín-Hernández, Miguel Ángel Sanchez-Luengo, Katharina Hess, Claudia Vales-Villamarín, Marta Barradas, Cian Lynch, Daniel de la Nava, Alberto Diaz-Ruiz, Rafael de Cabo, Marta Cañamero, Lola Martinez, Marta Sanchez-Carbayo, Daniel Herranz, Manuel Serrano, Pablo Jose Fernandez-Marcos
Sirt1 protects from K-Ras-driven lung carcinogenesis. EMBO reports 19 (9) (2018)

Manuel Serrano.css-eqlu8i{font-size:small;padding-left:4px;} (M Serrano)

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Manuel Serrano (M Serrano)