Maria Isabel Loza (María I Loza, María Isabel Loza, M Isabel Loza)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 33

Top Topics

Molecular Docking

Neuropathic Pain

Fluorescent Probe

Top Venues

Journal of medicinal chemistry

Disease models & mechanisms

ACS chemical neuroscience

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Breno A Soares, Thirumal Yempala, Darío Martínez-Afani, Williams Acevedo-Fuentes, José Brea, Maria Isabel Loza, Marta Cimadevila, Bruce K Cassels
Effect of Bulky N -Dibenzofuranylmethyl Substitution on the 5-HT 2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine. ACS chemical neuroscience (2024)
Francesca Intranuovo, Maria Majellaro, Francesco Mastropasqua, Pietro Delre, Francesca Serena Abatematteo, Giuseppe Felice Mangiatordi, Angela Stefanachi, Jose Brea, Maria Isabel Loza, Chiara Riganti, Alessia Ligresti, Poulami Kumar, Daniela Esposito, Luigia Cristino, Alessandro Nicois, Lucía González, Maria Grazia Perrone, Nicola Antonio Colabufo, Eddy Sotelo, Carmen Abate, Marialessandra Contino
N -Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R). Journal of medicinal chemistry (2024)
Breno A Soares, Thirumal Yempala, Darío Martínez-Afani, Williams Acevedo-Fuentes, José Brea, Maria Isabel Loza, Marta Cimadevila, Bruce K Cassels
Effect of Bulky N -Dibenzofuranylmethyl Substitution on the 5-HT 2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine. ACS chemical neuroscience 15 (3) (2024)
Breno A Soares, Thirumal Yempala, Darío Martínez-Afani, Williams Acevedo-Fuentes, José Brea, Maria Isabel Loza, Marta Cimadevila, Bruce K Cassels
Effect of Bulky N -Dibenzofuranylmethyl Substitution on the 5-HT 2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine. ACS chemical neuroscience 15 (3) (2024)
Francesca Intranuovo, Maria Majellaro, Francesco Mastropasqua, Pietro Delre, Francesca Serena Abatematteo, Giuseppe Felice Mangiatordi, Angela Stefanachi, Jose Brea, Maria Isabel Loza, Chiara Riganti, Alessia Ligresti, Poulami Kumar, Daniela Esposito, Luigia Cristino, Alessandro Nicois, Lucía González, Maria Grazia Perrone, Nicola Antonio Colabufo, Eddy Sotelo, Carmen Abate, Marialessandra Contino
N -Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R). Journal of medicinal chemistry 67 (13) (2024)
Francesca Intranuovo, Maria Majellaro, Francesco Mastropasqua, Pietro Delre, Francesca Serena Abatematteo, Giuseppe Felice Mangiatordi, Angela Stefanachi, Jose Brea, Maria Isabel Loza, Chiara Riganti, Alessia Ligresti, Poulami Kumar, Daniela Esposito, Luigia Cristino, Alessandro Nicois, Lucía González, Maria Grazia Perrone, Nicola Antonio Colabufo, Eddy Sotelo, Carmen Abate, Marialessandra Contino
N -Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R). Journal of medicinal chemistry 67 (13) (2024)
Breno A Soares, Thirumal Yempala, Darío Martínez-Afani, Williams Acevedo-Fuentes, José Brea, Maria Isabel Loza, Marta Cimadevila, Bruce K Cassels
Effect of Bulky N -Dibenzofuranylmethyl Substitution on the 5-HT 2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine. ACS chemical neuroscience 15 (3) (2024)
Sara C Silva-Reis, Xavier Cruz Correia, Hugo F Costa-Almeida, Beatriz L Pires-Lima, Daiane Maronde, Vera Marisa Costa, Xerardo García-Mera, Luís M Cruz, Jose Brea, Maria Isabel Loza, José E Rodríguez-Borges, Ivo E Sampaio-Dias
Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D 2 Receptors. ACS medicinal chemistry letters 14 (12) (2023)
Sara C Silva-Reis, Xavier Cruz Correia, Hugo F Costa-Almeida, Beatriz L Pires-Lima, Daiane Maronde, Vera Marisa Costa, Xerardo García-Mera, Luís M Cruz, Jose Brea, Maria Isabel Loza, José E Rodríguez-Borges, Ivo E Sampaio-Dias
Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D 2 Receptors. ACS medicinal chemistry letters 14 (12) (2023)
Javier Garcia-Carceles, Henar Vázquez-Villa, Jose Brea, David Ladron de Guevara-Miranda, Giovanni Cincilla, Melchor Sanchez-Martinez, Anabel Sánchez-Merino, Sergio Algar, María Teresa de Los Frailes, Richard S Roberts, Juan A Ballesteros, Fernando Rodríguez de Fonseca, Bellinda Benhamú, Maria Isabel Loza, Maria L López-Rodríguez
2-(Fluoromethoxy)-4'-( S -methanesulfonimidoyl)-1,1'-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D 1 Receptor for Parkinson's Disease. Journal of medicinal chemistry 65 (18) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Sandra Codony, Caterina Pont, Christian Griñán-Ferré, Ania Di Pede-Mattatelli, Carla Calvó-Tusell, Ferran Feixas, Sílvia Osuna, Júlia Jarné-Ferrer, Marina Naldi, Manuela Bartolini, Maria Isabel Loza, José Brea, Belén Pérez, Clara Bartra, Coral Sanfeliu, Jordi Juárez-Jiménez, Christophe Morisseau, Bruce D Hammock, Mercé Pallàs, Santiago Vázquez, Diego Muñoz-Torrero
Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry 65 (6) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Cristina Val, Carlos Rodríguez-García, Rubén Prieto-Díaz, Abel Crespo, Jhonny Azuaje, Carlos Carbajales, Maria Majellaro, Alejandro Díaz-Holguín, José M Brea, Maria Isabel Loza, Claudia Gioé-Gallo, Marialessandra Contino, Angela Stefanachi, Xerardo García-Mera, Juan C Estévez, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A 1 Antagonists. Journal of medicinal chemistry 65 (3) (2022)
Sandra Codony, José M Entrena, Carla Calvó-Tusell, Beatrice Jora, Rafael González-Cano, Sílvia Osuna, Rubén Corpas, Christophe Morisseau, Belén Pérez, Marta Barniol-Xicota, Christian Griñán-Ferré, Concepción Pérez, María Isabel Rodríguez-Franco, Antón L Martínez, Maria Isabel Loza, Mercé Pallàs, Steven H L Verhelst, Coral Sanfeliu, Ferran Feixas, Bruce D Hammock, Jose Brea, Enrique J Cobos, Santiago Vázquez
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors. Journal of medicinal chemistry 65 (20) (2022)
María Carmen Costas-Lago, Noemí Vila, Adeyemi Rahman, Pedro Besada, Isabel Rozas, José Brea, Maria Isabel Loza, Elisa González Romero, Carmen Terán
Novel Pyridazin-3(2 H )-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity. ACS medicinal chemistry letters 13 (3) (2022)
Darío Miranda-Pastoriza, Rodrigo Bernárdez, Jhonny Azuaje, Rubén Prieto-Díaz, Maria Majellaro, Ashish V Tamhankar, Lucien Koenekoop, Alejandro González, Claudia Gioé-Gallo, Ana Mallo-Abreu, José Brea, Maria Isabel Loza, Aitor García-Rey, Xerardo García-Mera, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring Non-orthosteric Interactions with a Series of Potent and Selective A 3 Antagonists. ACS medicinal chemistry letters 13 (2) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E Audia, Sohini Chowdhury, Shannon Weiman, Kalpana M Merchant, Maria-Jesus Blanco
Collaboration and knowledge integration for successful brain therapeutics - lessons learned from the pandemic. Disease models & mechanisms 15 (12) (2022)
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E Audia, Sohini Chowdhury, Shannon Weiman, Kalpana M Merchant, Maria-Jesus Blanco
Collaboration and knowledge integration for successful brain therapeutics - lessons learned from the pandemic. Disease models & mechanisms 15 (12) (2022)
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E Audia, Sohini Chowdhury, Shannon Weiman, Kalpana M Merchant, Maria-Jesus Blanco
Collaboration and knowledge integration for successful brain therapeutics - lessons learned from the pandemic. Disease models & mechanisms 15 (12) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry (2022)
Juan M Decara, Henar Vázquez-Villa, José Brea, Mónica Alonso, Raj Kamal Srivastava, Laura Orio, Francisco Alén, Juan Suárez, Elena Baixeras, Javier Garcia-Carceles, Andrea Escobar-Peña, Beat Lutz, Ramón Rodríguez, Eva Codesido, F Javier Garcia-Ladona, Teresa A Bennett, Juan A Ballesteros, Jacobo Cruces, Maria Isabel Loza, Bellinda Benhamú, Fernando Rodríguez de Fonseca, Maria L López-Rodríguez
Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity". Journal of medicinal chemistry 65 (7) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry (2022)
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E Audia, Sohini Chowdhury, Shannon Weiman, Kalpana M Merchant, Maria-Jesus Blanco
Collaboration and knowledge integration for successful brain therapeutics - lessons learned from the pandemic. Disease models & mechanisms 15 (12) (2022)
Rubén Prieto-Díaz, Manuel González-Gómez, Hugo Fojo-Carballo, Jhonny Azuaje, Abdelaziz El Maatougui, Maria Majellaro, Maria Isabel Loza, Jose Brea, Víctor Fernández-Dueñas, M Rita Paleo, Alejandro Díaz-Holguín, Beatriz García-Pinel, Ana Mallo-Abreu, Juan C Estévez, Antonio Andújar-Arias, Xerardo García-Mera, Iria Gomez-Tourino, Francisco Ciruela, Cristian O Salas, Hugo Gutiérrez-de-Terán, Eddy Sotelo
Exploring the Effect of Halogenation in a Series of Potent and Selective A 2B Adenosine Receptor Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E Audia, Sohini Chowdhury, Shannon Weiman, Kalpana M Merchant, Maria-Jesus Blanco
Collaboration and knowledge integration for successful brain therapeutics - lessons learned from the pandemic. Disease models & mechanisms 15 (12) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, Maria Isabel Loza
Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening. PloS one 16 (3) (2021)
Antón L Martínez, José Brea, Eduardo Domínguez, María J Varela, Marta Cimadevila, Catarina Allegue, Raquel Cruz, Xavier Monroy, Manuel Merlos, Javier Burgueño, Ángel Carracedo, Maria Isabel Loza
Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain. ACS chemical neuroscience 12 (14) (2021)