Sílvia Osuna (S Osuna)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 38

Top Venues

Journal of the American Chemical Society

Journal of medicinal chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

JACS Au

Universitat de Girona

Universitat de Girona Facultat de Ciències (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universitat de Girona Jan 01 2016

Spain

Ramón y Cajal contract :: Quimica

Universitat de Girona Dec 01 2013 - Dec 31 2015

Spain

Juan de la Cierva contract :: Quimica

Education History

Universitat de Girona Facultat de Ciències

Spain

PHD

Publications

Cristina Duran, Guillem Casadevall, Sílvia Osuna
Harnessing conformational dynamics in enzyme catalysis to achieve nature-like catalytic efficiencies: the shortest path map tool for computational enzyme redesign. Faraday discussions (2024)
Guillem Casadevall, Jordi Casadevall, Cristina Duran, Sílvia Osuna
The shortest path method (SPM) webserver for computational enzyme design. Protein engineering, design & selection : PEDS 37 (2024)
Guillem Casadevall, Jordi Casadevall, Cristina Duran, Sílvia Osuna
The shortest path method (SPM) webserver for computational enzyme design. Protein engineering, design & selection : PEDS (2024)
Carlos Acevedo-Rocha, Amulyasai Bakshi, Uwe T Bornscheuer, Dominic J Campopiano, Janko Čivić, Ivana Drienovská, Friedrich Johannes Ehinger, Andrew Gomm, Artur Góra, Anthony P Green, Marko Hanzevacki, Jeremy N Harvey, Donald Hilvert, Meilan Huang, Amanda G Jarvis, Shina Caroline Lynn Kamerlin, Bruce R Lichtenstein, Louis Y P Luk, Stefan Lutz, E Neil G Marsh, Alexander McKenzie, Vicent Moliner, Adrian J Mulholland, Sílvia Osuna, Joelle N Pelletier, Agata Raczyńska, Aditya Gopalakrishna Rao, Guto G Rhys, Gerard Roelfes, Lubomír Rulíšek, Peter Stockinger, Katarzyna Szleper, Sean Adeoti Thompson, Nicholas Turner, Marc W Van der Kamp, Guangcai Xu, Cathleen Zeymer
Artificial, biomimetic and hybrid enzymes: general discussion. Faraday discussions (2024)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society 146 (1) (2023)
Guillem Casadevall, Cristina Duran, Sílvia Osuna
AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design. JACS Au 3 (6) (2023)
Andrea Palone, Guillem Casadevall, Sergi Ruiz-Barragan, Arnau Call, Sílvia Osuna, Massimo Bietti, Miquel Costas
C-H Bonds as Functional Groups: Simultaneous Generation of Multiple Stereocenters by Enantioselective Hydroxylation at Unactivated Tertiary C-H Bonds. Journal of the American Chemical Society (2023)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society 146 (1) (2023)
Guillem Casadevall, Colin T Pierce, Bo Guan, Javier Iglesias-Fernandez, Huey-Yee Lim, Lauren R Greenberg, Meghan E Walsh, Ke Shi, Wendy Gordon, Hideki Aihara, Robert L Evans, Romas J Kazlauskas, Sílvia Osuna
Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase. bioRxiv : the preprint server for biology (2023)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society 146 (1) (2023)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society (2023)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society 146 (1) (2023)
Guillem Casadevall, Cristina Duran, Sílvia Osuna
AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design. JACS Au 3 (6) (2023)
Matteo Castelli, Filippo Marchetti, Sílvia Osuna, Ana Sofia F Oliveira, Adrian J Mulholland, Stefano Artin Serapian, Giorgio Colombo
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. Journal of the American Chemical Society 146 (1) (2023)
Guillem Casadevall, Cristina Duran, Sílvia Osuna
AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design. JACS Au 3 (6) (2023)
Sandra Codony, Caterina Pont, Christian Griñán-Ferré, Ania Di Pede-Mattatelli, Carla Calvó-Tusell, Ferran Feixas, Sílvia Osuna, Júlia Jarné-Ferrer, Marina Naldi, Manuela Bartolini, Maria Isabel Loza, José Brea, Belén Pérez, Clara Bartra, Coral Sanfeliu, Jordi Juárez-Jiménez, Christophe Morisseau, Bruce D Hammock, Mercé Pallàs, Santiago Vázquez, Diego Muñoz-Torrero
Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry 65 (6) (2022)
Guillem Casadevall, Cristina Duran, Miquel Estévez-Gay, Sílvia Osuna
Estimating conformational heterogeneity of tryptophan synthase with a template-based Alphafold2 approach. Protein science : a publication of the Protein Society 31 (10) (2022)
Sandra Codony, José M Entrena, Carla Calvó-Tusell, Beatrice Jora, Rafael González-Cano, Sílvia Osuna, Rubén Corpas, Christophe Morisseau, Belén Pérez, Marta Barniol-Xicota, Christian Griñán-Ferré, Concepción Pérez, María Isabel Rodríguez-Franco, Antón L Martínez, Maria Isabel Loza, Mercé Pallàs, Steven H L Verhelst, Coral Sanfeliu, Ferran Feixas, Bruce D Hammock, Jose Brea, Enrique J Cobos, Santiago Vázquez
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors. Journal of medicinal chemistry 65 (20) (2022)
Carla Calvó-Tusell, Miguel A Maria-Solano, Sílvia Osuna, Ferran Feixas
Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase. Journal of the American Chemical Society 144 (16) (2022)
Miguel A Maria-Solano, Thomas Kinateder, Javier Iglesias-Fernandez, Reinhard Sterner, Sílvia Osuna
In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase. ACS catalysis 11 (21) (2021)
Sandra Codony, Carla Calvó-Tusell, Elena Valverde, Sílvia Osuna, Christophe Morisseau, M Isabel Loza, José Brea, Concepción Pérez, María Isabel Rodríguez-Franco, Javier Pizarro-Delgado, Rubén Corpas, Christian Griñán-Ferré, Mercé Pallàs, Coral Sanfeliu, Manuel Vázquez-Carrera, Bruce D Hammock, Ferran Feixas, Santiago Vázquez
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. Journal of medicinal chemistry 64 (9) (2021)
Martin Floor, Kengjie Li, Miquel Estévez-Gay, Luis Agulló, Pau Marc Muñoz-Torres, Jenn K Hwang, Sílvia Osuna, Jordi Villà-Freixa
SBMOpenMM: A Builder of Structure-Based Models for OpenMM. Journal of chemical information and modeling 61 (7) (2021)
Carlos G Acevedo-Rocha, Aitao Li, Lorenzo D'Amore, Sabrina Hoebenreich, Joaquin Sanchis, Paul Lubrano, Matteo P Ferla, Marc Garcia-Borràs, Sílvia Osuna, Manfred T Reetz
Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics. Nature communications 12 (1) (2021)
Olesya Semivrazhskaya, Safwan Aroua, Maxim Yulikov, Adrian Romero-Rivera, Steven Stevenson, Marc Garcia-Borràs, Sílvia Osuna, Yoko Yamakoshi
Regioselective Synthesis and Characterization of Tris- and Tetra-Prato Adducts of M3N@C80 (M = Y, Gd). Journal of the American Chemical Society 142 (30) (2020)
Sandra Codony, Eugènia Pujol, Javier Pizarro, Ferran Feixas, Elena Valverde, M Isabel Loza, José M Brea, Elena Saez, Julen Oyarzábal, Antonio Pineda-Lucena, Belén Pérez, Concepción Pérez, María Isabel Rodríguez-Franco, Rosana Leiva, Sílvia Osuna, Christophe Morisseau, Bruce D Hammock, Manuel Vázquez-Carrera, Santiago Vázquez
2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis. Journal of medicinal chemistry 63 (17) (2020)
Abril C Castro, Adrian Romero-Rivera, Sílvia Osuna, Kendall N Houk, Marcel Swart
Computational NMR Spectra of o-Benzyne and Stable Guests and Their Hemicarceplexes. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (12) (2020)
Mantas Liutkus, Alicia López-Andarias, Sara H Mejias, Alicia López-Andarias, David Gil-Carton, Ferran Feixas, Sílvia Osuna, Wakana Matsuda, Tsuneaki Sakurai, Shu Seki, Carmen Atienza, Nazario Martin, Aitziber L Cortajarena
Protein-directed crystalline 2D fullerene assemblies. Nanoscale 12 (6) (2020)
Aitao Li, Carlos G Acevedo-Rocha, Lorenzo D'Amore, Jinfeng Chen, Yaqin Peng, Marc Garcia-Borràs, Chenghua Gao, Jinmei Zhu, Harry Rickerby, Sílvia Osuna, Jiahai Zhou, Manfred T Reetz
Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angewandte Chemie (International ed. in English) 59 (30) (2020)
Olesya Semivrazhskaya, Adrian Romero-Rivera, Safwan Aroua, Sergey I Troyanov, Marc Garcia-Borràs, Steven Stevenson, Sílvia Osuna, Yoko Yamakoshi
Structures of Gd3N@C80 Prato Bis-Adducts: Crystal Structure, Thermal Isomerization, and Computational Study. Journal of the American Chemical Society 141 (28) (2019)
Miguel A Maria-Solano, Javier Iglesias-Fernandez, Sílvia Osuna
Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution. Journal of the American Chemical Society 141 (33) (2019)
Korinne Liosi, Adrian Romero-Rivera, Olesya Semivrazhskaya, Caravaggio D Caniglia, Marc Garcia-Borràs, Nils Trapp, Sílvia Osuna, Yoko Yamakoshi
Site-Selectivity of Prato Additions to C70: Experimental and Theoretical Studies of a New Thermodynamic Product at the dd-[5,6]-Junction. Organic letters 21 (13) (2019)
Christian Curado-Carballada, Ferran Feixas, Javier Iglesias-Fernández, Sílvia Osuna
Hidden Conformations in Aspergillus niger Monoamine Oxidase are Key for Catalytic Efficiency. Angewandte Chemie (International ed. in English) 58 (10) (2019)
Eila Serrano-Hervás, Marc Garcia-Borràs, Sílvia Osuna
Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium. Organic & biomolecular chemistry 15 (41) (2018)
Marc Garcia-Borràs, Sílvia Osuna, Josep M Luis, Miquel Solá
Rationalizing the relative abundances of trimetallic nitride template-based endohedral metallofullerenes from aromaticity measures. Chemical communications (Cambridge, England) 53 (29) (2018)
Eila Serrano-Hervás, Guillem Casadevall, Marc Garcia-Borràs, Ferran Feixas, Sílvia Osuna
Epoxide Hydrolase Conformational Heterogeneity for the Resolution of Bulky Pharmacologically Relevant Epoxide Substrates. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (47) (2018)
Guangyue Li, Miguel A Maria-Solano, Adrian Romero-Rivera, Sílvia Osuna, Manfred T Reetz
Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution. Chemical communications (Cambridge, England) 53 (68) (2018)
Adrian Romero-Rivera, Marc Garcia-Borràs, Sílvia Osuna
Computational tools for the evaluation of laboratory-engineered biocatalysts. Chemical communications (Cambridge, England) 53 (2) (2017)
Juan Pablo Martínez, Marc Garcia-Borràs, Sílvia Osuna, Jordi Poater, Friedrich Matthias Bickelhaupt, Miquel Solá
Reaction Mechanism and Regioselectivity of the Bingel-Hirsch Addition of Dimethyl Bromomalonate to La@C2v -C82. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (17) (2016)

Sílvia Osuna.css-eqlu8i{font-size:small;padding-left:4px;} (S Osuna)

Publication Activity (10 Years)

Top Topics

Top Venues

Sílvia Osuna (S Osuna)