Matthew R Redinbo

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Venues

University of North Carolina at Chapel Hill

University of California Los Angeles (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of North Carolina at Chapel Hill Jul 01 1999

United States

Distinguished Professor :: Chemistry, Biochemistry, Microbiology, iBGS

University of Washington Sep 01 1995 - Jun 01 1999

United States

Postdoctoral Fellow :: Structural Biology

Education History

University of California Los Angeles Sep 01 1990 - May 15 1995

United States

PHD :: Chemistry and Biochemistry

University of California Davis Sep 01 1985 - Jun 15 1990

United States

BSC :: Biochemistry

Publications

Amanda L Graboski, Joshua B Simpson, Samuel J Pellock, Naimee Mehta, Benjamin C Creekmore, Yamuna Ariyarathna, Aadra P Bhatt, Parth B Jariwala, Josh J Sekela, Mark E Kowalewski, Natalie K Barker, Angie L Mordant, Valentina B Borlandelli, Herman S Overkleeft, Laura E Herring, Jian Jin, Lindsey I James, Matthew R Redinbo
Advanced piperazine-containing inhibitors target microbial β-glucuronidases linked to gut toxicity. RSC chemical biology 5 (9) (2024)
Adam D Lietzan, Joshua B Simpson, William G Walton, Parth B Jariwala, Yongmei Xu, Marcella H Boynton, Katelyn Arnold, Matthew R Redinbo
Microbial β-glucuronidases drive human periodontal disease etiology. Science advances 9 (18) (2023)
Adam D Lietzan, Joshua B Simpson, William G Walton, Parth B Jariwala, Yongmei Xu, Marcella H Boynton, Katelyn Arnold, Matthew R Redinbo
Microbial β-glucuronidases drive human periodontal disease etiology. Science advances 9 (18) (2023)
Adam D Lietzan, Joshua B Simpson, William G Walton, Parth B Jariwala, Yongmei Xu, Marcella H Boynton, Katelyn Arnold, Matthew R Redinbo
Microbial β-glucuronidases drive human periodontal disease etiology. Science advances 9 (18) (2023)
Matthew H Foley, Morgan E Gibbs, Allison K Stewart, Sarah O'Flaherty, Emily C Gentry, Shakshi Patel, Violet V Beaty, Garrison Allen, Meichen Pan, Joshua B Simpson, Caroline Perkins, Molly E Vanhoy, Michael K Dougherty, Sarah K McGill, Ajay S Gulati, Pieter C Dorrestein, Erin S Baker, Matthew R Redinbo, Rodolphe Barrangou, Casey M Theriot
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. Nature microbiology (2023)
Adam D Lietzan, Joshua B Simpson, William G Walton, Parth B Jariwala, Yongmei Xu, Marcella H Boynton, Katelyn Arnold, Matthew R Redinbo
Microbial β-glucuronidases drive human periodontal disease etiology. Science advances 9 (18) (2023)
Joshua B Simpson, Josh J Sekela, Benjamin S Carry, Violet Beaty, Shakshi Patel, Matthew R Redinbo
Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response. Gut microbes 15 (1) (2023)
Joshua B Simpson, Josh J Sekela, Benjamin S Carry, Violet Beaty, Shakshi Patel, Matthew R Redinbo
Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response. Gut microbes 15 (1) (2023)
Adam D Lietzan, Joshua B Simpson, William G Walton, Parth B Jariwala, Yongmei Xu, Marcella H Boynton, Katelyn Arnold, Matthew R Redinbo
Microbial β-glucuronidases drive human periodontal disease etiology. Science advances 9 (18) (2023)
Anna Kerins, Marta Koszyczarek, Caroline Smith, Phil Butler, Rob Riley, Vamsi Madgula, Nilkanth Naik, Matthew R Redinbo, Ian D Wilson
The in vitro metabolism and in vivo pharmacokinetics of the bacterial β-glucuronidase inhibitor UNC10201652. Xenobiotica; the fate of foreign compounds in biological systems (2022)
Joshua B Simpson, Josh J Sekela, Amanda L Graboski, Valentina B Borlandelli, Marissa M Bivins, Natalie K Barker, Alicia A Sorgen, Angie L Mordant, Rebecca L Johnson, Aadra P Bhatt, Anthony A Fodor, Laura E Herring, Hermen Overkleeft, John R Lee, Matthew R Redinbo
Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate. Gut microbes 14 (1) (2022)
Jonathan M Conway, William G Walton, Isai Salas-González, Theresa F Law, Chloe A Lindberg, Laura E Crook, Suzanne M Kosina, Connor R Fitzpatrick, Adam D Lietzan, Trent R Northen, Corbin D Jones, Omri M Finkel, Matthew R Redinbo, Jeffery L Dangl
Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nature microbiology 7 (11) (2022)
Adam L Edwinson, Lu Yang, Stephanie Peters, Nikita Hanning, Patricio Jeraldo, Pratik D Jagtap, Joshua B Simpson, Tzu-Yi Yang, Praveen Kumar, Subina Mehta, Asha Nair, Margaret Breen-Lyles, Lakshmikanth Chikkamenahalli, Rondell P Graham, Benedicte Y De Winter, Robin Patel, Surendra Dasari, Purna C Kashyap, Timothy J Griffin, Jun Chen, Gianrico Farrugia, Matthew R Redinbo, Madhusudan Grover
Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome. Nature microbiology 7 (5) (2022)
Joshua B Simpson, Matthew R Redinbo
Multi-omic analysis of host-microbial interactions central to the gut-brain axis. Molecular omics 18 (10) (2022)
Guodong Zhang, Morgan E Gibbs, Katherine Z Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, Katherine Chacon-Vargas, Vladimir Yeliseyev, Julie Parsonnet, Thomas D Haggerty, Guangqiang Wang, Joshua B Simpson, Parth B Jariwala, Violet V Beaty, Jun Yang, Haixia Yang, Anand Panigrahy, Lisa M Minter, Daeyoung Kim, John G Gibbons, LinShu Liu, Zhengze Li, Hang Xiao, Valentina Borlandelli, Hermen S Overkleeft, Erica W Cloer, Michael B Major, Dennis Goldfrab, Zongwei Cai, Matthew R Redinbo, Guodong Zhang
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nature communications 13 (1) (2022)
Pierre Jacob, Nak Hyun Kim, Feihua Wu, Farid El Kasmi, Yuan Chi, William G Walton, Oliver J Furzer, Adam D Lietzan, Sruthi Sunil, Korina Kempthorn, Matthew R Redinbo, Zhen-Ming Pei, Li Wan, Jeffery L Dangl
Plant "helper" immune receptors are Ca2+-permeable nonselective cation channels. Science (New York, N.Y.) 373 (6553) (2021)
Samantha M Ervin, Joshua B Simpson, Morgan E Gibbs, Benjamin C Creekmore, Lauren Lim, William G Walton, Raad Z Gharaibeh, Matthew R Redinbo
Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases. Biochemistry 59 (40) (2020)
Aadra P Bhatt, Samuel J Pellock, Kristen A Biernat, William G Walton, Bret D Wallace, Benjamin C Creekmore, Marine M Letertre, Jonathan R Swann, Ian D Wilson, Jose R Roques, David B Darr, Sean T Bailey, Stephanie A Montgomery, Jeffrey M Roach, Maria Andrea Azcarate-Peril, R Balfour Sartor, Raad Z Gharaibeh, Scott J Bultman, Matthew R Redinbo
Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Amanda L Graboski, Matthew R Redinbo
Gut-Derived Protein-Bound Uremic Toxins. Toxins 12 (9) (2020)
Desirée Bartolini, Francesca De Franco, Pierangelo Torquato, Rita Marinelli, Bruno Cerra, Riccardo Ronchetti, Arne Schon, Francesca Fallarino, Antonella De Luca, Guido Bellezza, Ivana Ferri, Angelo Sidoni, William G Walton, Samuel J Pellock, Matthew R Redinbo, Sridhar Mani, Roberto Pellicciari, Antimo Gioiello, Francesco Galli
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor. Journal of medicinal chemistry 63 (7) (2020)
Samantha M Ervin, Ronan P Hanley, Lauren Lim, William G Walton, Kenneth H Pearce, Aadra P Bhatt, Lindsey I James, Matthew R Redinbo
Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial β-Glucuronidases. ACS chemical biology 14 (12) (2019)
Parth B Jariwala, Samuel J Pellock, Dennis Goldfarb, Erica W Cloer, Marta Artola, Joshua B Simpson, Aadra P Bhatt, William G Walton, Lee R Roberts, Michael B Major, Gideon J Davies, Herman S Overkleeft, Matthew R Redinbo
Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. ACS chemical biology 15 (1) (2019)
Benjamin C Creekmore, Josh H Gray, William G Walton, Kristen A Biernat, Michael S Little, Yongmei Xu, Jian Liu, Raad Z Gharaibeh, Matthew R Redinbo
Mouse Gut Microbiome-Encoded β-Glucuronidases Identified Using Metagenome Analysis Guided by Protein Structure. mSystems 4 (4) (2019)
Samuel J Pellock, William G Walton, Matthew R Redinbo
Selecting a Single Stereocenter: The Molecular Nuances That Differentiate β-Hexuronidases in the Human Gut Microbiome. Biochemistry 58 (9) (2019)
Aadra P Bhatt, Dulan B Gunasekara, Jennifer Speer, Mark I Reed, Alexis N Peña, Bentley R Midkiff, Scott T Magness, Scott J Bultman, Nancy L Allbritton, Matthew R Redinbo
Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells. ACS infectious diseases 4 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Matthew R Redinbo