Martijn Paul Lolkema (Martijn Lolkema, Martijn P Lolkema)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 33

Top Topics

Duchenne Muscular Dystrophy

Radical Prostatectomy

Circulating Tumor

Top Venues

Nature communications

Clinical cancer research : an official journal of the American Association for Cancer Research

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Maud Rijnders, José Alberto Nakauma-González, Debbie G J Robbrecht, Alberto Gil-Jimenez, Hayri E Balcioglu, Astrid A M Oostvogels, Maureen J B Aarts, Joost L Boormans, Paul Hamberg, Michiel S Van Der Heijden, Bernadett E Szabados, G J L H Geert van Leenders, Niven Mehra, Jens Voortman, Hans M Westgeest, Ronald de Wit, Astrid A M van der Veldt, Reno Debets, Martijn Paul Lolkema
Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer. Nature communications 15 (1) (2024)
Tanya Barauskas Dorff, Lisa G Horvath, Karen A Autio, Alice Bernard-Tessier, Matthew B Rettig, Jean-Pascal H Machiels, Mehmet Asim Bilen, Martijn Paul Lolkema, Nabil Adra, Sylvie Rottey, Richard Greil, Nobuaki Matsubara, Daniel Shao-Weng Tan, Alvin S C Wong, Hiroji Uemura, Charlotte Lemech, Johannes Meran, Youfei Yu, Mukul Minocha, Mason McComb, Hweixian Leong Penny, Vinita Gupta, Xuguang Hu, Gabor Jurida, Hosein Kouros-Mehr, Margit M Janát-Amsbury, Tobias Eggert, Ben Tran
A phase 1 study of acapatamab, a half-life extended, PSMA-targeting bispecific T-cell engager for metastatic castration-resistant prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Maud Rijnders, José Alberto Nakauma-González, Debbie G J Robbrecht, Alberto Gil-Jimenez, Hayri E Balcioglu, Astrid A M Oostvogels, Maureen J B Aarts, Joost L Boormans, Paul Hamberg, Michiel S Van Der Heijden, Bernadett E Szabados, G J L H Geert van Leenders, Niven Mehra, Jens Voortman, Hans M Westgeest, Ronald de Wit, Astrid A M van der Veldt, Reno Debets, Martijn Paul Lolkema
Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer. Nature communications 15 (1) (2024)
Maud Rijnders, José Alberto Nakauma-González, Debbie G J Robbrecht, Alberto Gil-Jimenez, Hayri E Balcioglu, Astrid A M Oostvogels, Maureen J B Aarts, Joost L Boormans, Paul Hamberg, Michiel S Van Der Heijden, Bernadett E Szabados, G J L H Geert van Leenders, Niven Mehra, Jens Voortman, Hans M Westgeest, Ronald de Wit, Astrid A M van der Veldt, Reno Debets, Martijn Paul Lolkema
Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer. Nature communications 15 (1) (2024)
Tanya Barauskas Dorff, Lisa G Horvath, Karen A Autio, Alice Bernard-Tessier, Matthew B Rettig, Jean-Pascal H Machiels, Mehmet Asim Bilen, Martijn Paul Lolkema, Nabil Adra, Sylvie Rottey, Richard Greil, Nobuaki Matsubara, Daniel Shao-Weng Tan, Alvin S C Wong, Hiroji Uemura, Charlotte Lemech, Johannes Meran, Youfei Yu, Mukul Minocha, Mason McComb, Hweixian Leong Penny, Vinita Gupta, Xuguang Hu, Gabor Jurida, Hosein Kouros-Mehr, Margit M Janát-Amsbury, Tobias Eggert, Ben Tran
A Phase I Study of Acapatamab, a Half-life Extended, PSMA-Targeting Bispecific T-cell Engager for Metastatic Castration-Resistant Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Maud Rijnders, José Alberto Nakauma-González, Debbie G J Robbrecht, Alberto Gil-Jimenez, Hayri E Balcioglu, Astrid A M Oostvogels, Maureen J B Aarts, Joost L Boormans, Paul Hamberg, Michiel S Van Der Heijden, Bernadett E Szabados, G J L H Geert van Leenders, Niven Mehra, Jens Voortman, Hans M Westgeest, Ronald de Wit, Astrid A M van der Veldt, Reno Debets, Martijn Paul Lolkema
Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer. Nature communications 15 (1) (2024)
Tanya Barauskas Dorff, Lisa G Horvath, Karen A Autio, Alice Bernard-Tessier, Matthew B Rettig, Jean-Pascal H Machiels, Mehmet Asim Bilen, Martijn Paul Lolkema, Nabil Adra, Sylvie Rottey, Richard Greil, Nobuaki Matsubara, Daniel Shao-Weng Tan, Alvin S C Wong, Hiroji Uemura, Charlotte Lemech, Johannes Meran, Youfei Yu, Mukul Minocha, Mason McComb, Hweixian Leong Penny, Vinita Gupta, Xuguang Hu, Gabor Jurida, Hosein Kouros-Mehr, Margit M Janát-Amsbury, Tobias Eggert, Ben Tran
A Phase I Study of Acapatamab, a Half-life Extended, PSMA-Targeting Bispecific T-cell Engager for Metastatic Castration-Resistant Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Khrystany T Isebia, Martijn Paul Lolkema, Guido W Jenster, Ronald de Wit, John W M Martens, Job van Riet
A Compendium of AR Splice Variants in Metastatic Castration-Resistant Prostate Cancer. International journal of molecular sciences 24 (6) (2023)
Melinda A Pruis, Matthew G Krebs, Ruth Plummer, Filip Yves Francine De Vos, Eric Angevin, Hans Prenen, Martin D Forster, Glen Clack, Annegret Van der Aa, Marc Tjwa, Ellen Jansen, Timothy Perera, Martijn Paul Lolkema
A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer. The oncologist (2023)
Khrystany T Isebia, Martijn Paul Lolkema, Guido W Jenster, Ronald de Wit, John W M Martens, Job van Riet
A Compendium of AR Splice Variants in Metastatic Castration-Resistant Prostate Cancer. International journal of molecular sciences 24 (6) (2023)
Anouk C de Jong, Khrystany T Isebia, Sui Wai Ling, Vanja de Weerd, Ngoc M Van, Jaco Kraan, John W M Martens, Niven Mehra, Paul Hamberg, Martijn Paul Lolkema, Ronald de Wit, Astrid A M van der Veldt, Saskia M Wilting
Liquid Biopsies for Early Response Evaluation of Radium-223 in Metastatic Prostate Cancer. JCO precision oncology 7 (2023)
Anouk C de Jong, Khrystany T Isebia, Sui Wai Ling, Vanja de Weerd, Ngoc M Van, Jaco Kraan, John W M Martens, Niven Mehra, Paul Hamberg, Martijn Paul Lolkema, Ronald de Wit, Astrid A M van der Veldt, Saskia M Wilting
Liquid Biopsies for Early Response Evaluation of Radium-223 in Metastatic Prostate Cancer. JCO precision oncology 7 (2023)
Khrystany T Isebia, Martijn Paul Lolkema, Guido W Jenster, Ronald de Wit, John W M Martens, Job van Riet
A Compendium of AR Splice Variants in Metastatic Castration-Resistant Prostate Cancer. International journal of molecular sciences 24 (6) (2023)
Anouk C de Jong, Khrystany T Isebia, Sui Wai Ling, Vanja de Weerd, Ngoc M Van, Jaco Kraan, John W M Martens, Niven Mehra, Paul Hamberg, Martijn Paul Lolkema, Ronald de Wit, Astrid A M van der Veldt, Saskia M Wilting
Liquid Biopsies for Early Response Evaluation of Radium-223 in Metastatic Prostate Cancer. JCO precision oncology 7 (2023)
Anouk C de Jong, Alexandra Danyi, Job van Riet, Ronald de Wit, Martin Sjostrom, Felix Y Feng, Jeroen de Ridder, Martijn Paul Lolkema
Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning. Nature communications 14 (1) (2023)
Lindsay Angus, Marcel Smid, Saskia M Wilting, Manouk K Bos, Neeltje Steeghs, Inge R H M Konings, Vivianne C G Tjan-Heijnen, Johanna M G H van Riel, Agnes J van de Wouw, null Cpct Consortium, Edwin Cuppen, Martijn Paul Lolkema, Agnes Jager, Stefan Sleijfer, John W M Martens
Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling. Cancers 15 (17) (2023)
Louisa R Hoes, J Maxime van Berge Henegouwen, Hanneke van der Wijngaart, Laurien J Zeverijn, Daphne L van der Velden, Joris van de Haar, Paul Roepman, Wendy W J de Leng, Anne M L Jansen, Erik D van Werkhoven, Vincent van den Noort, Alwin D R Huitema, Eelke H Gort, Jan Willem B de Groot, Emile D Kerver, Derk-Jan A de Groot, Frans Erdkamp, Laurens V Beerepoot, Marieke H J van den Beuken-van Everdingen, Egbert F Smit, Winette T A van der Graaf, Carla M L van Herpen, Mariette Labots, Ann Hoeben, Hans Morreau, Martijn Paul Lolkema, Edwin Cuppen, André B P van Kuilenburg, Henk M W Verheul, Emile E Voest
Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (7) (2022)
Khrystany T Isebia, Eshwari Dathathri, Noortje Verschoor, Afroditi Nanou, Anouk C de Jong, Frank A W Coumans, Leon W M M Terstappen, Jaco Kraan, John W M Martens, Ruchi Bansal, Martijn Paul Lolkema
Characterizing Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles in Metastatic Castration-Naive and Castration-Resistant Prostate Cancer Patients. Cancers 14 (18) (2022)
Melinda A Pruis, Floris H Groenendijk, K Sangeeta Badloe, Andrea van Puffelen, Debbie G J Robbrecht, Winand N M Dinjens, Stefan Sleijfer, Anne-Marie C Dingemans, Jan H von der Thusen, Paul Roepman, Martijn Paul Lolkema
Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing. British journal of cancer 127 (4) (2022)
Liza G G van Lent, Maja J A de Jonge, Mirte van der Ham, Marjolein van Mil, Eelke H Gort, Jeroen Hasselaar, Esther Oomen-de Hoop, Carin C D van der Rijt, Julia C M van Weert, Martijn Paul Lolkema
Decisional Conflict after Deciding on Potential Participation in Early Phase Clinical Cancer Trials: Dependent on Global Health Status, Satisfaction with Communication, and Timing. Cancers 14 (6) (2022)
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, null null, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn Paul Lolkema, Neeltje Steeghs, Gad A Getz, Quaid D Morris, Lincoln D Stein, null null
Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature communications 13 (1) (2022)
Sylvie Rottey, Jeffrey Clarke, Kyaw Aung, Jean-Pascal Machiels, Ben Markman, Kimberley M Heinhuis, Michael Millward, Martijn Paul Lolkema, Sandip Pravin Patel, Paul de Souza, Matteo Duca, Curigliano Giuseppe, Armando Santoro, Takafumi Koyama, Michelle Brown, Heather Vezina, Chunsheng He, Quincy Siu-Chung Chu
Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Maud Rijnders, Hayri E Balcioglu, Debbie G J Robbrecht, Astrid A M Oostvogels, Rebecca Wijers, Maureen J B Aarts, Paul Hamberg, G J L H Geert van Leenders, José Alberto Nakauma-González, Jens Voortman, Hans M Westgeest, Joost L Boormans, Ronald de Wit, Martijn Paul Lolkema, Astrid A M van der Veldt, Reno Debets
Anti-PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8+ T cells. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Pauline A J Mendelaar, Marcel Smid, Job van Riet, Lindsay Angus, Mariette Labots, Neeltje Steeghs, Marieke H J van den Beuken-van Everdingen, Geert A Cirkel, Johan M van Rooijen, Albert J Ten Tije, Martijn Paul Lolkema, Edwin Cuppen, Stefan Sleijfer, John W M Martens, Saskia M Wilting
Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features. Nature communications 12 (1) (2021)
Emre Kocakavuk, Kevin J Anderson, Frederick S Varn, Kevin C Johnson, Samirkumar B Amin, Erik P Sulman, Martijn Paul Lolkema, Floris P Barthel, Roel G W Verhaak
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer. Nature genetics 53 (7) (2021)
Job van Riet, Harmen J G van de Werken, Edwin Cuppen, Ferry A L M Eskens, Margot Tesselaar, Linde M van Veenendaal, Heinz-Josef Klümpen, Marcus W Dercksen, Gerlof D Valk, Martijn Paul Lolkema, Stefan Sleijfer, Bianca Mostert
The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets. Nature communications 12 (1) (2021)
Pauline A J Mendelaar, Marcel Smid, Job van Riet, Lindsay Angus, Mariette Labots, Neeltje Steeghs, Marieke H J van den Beuken-van Everdingen, Geert A Cirkel, Johan M van Rooijen, Albert J Ten Tije, Martijn Paul Lolkema, Edwin Cuppen, Stefan Sleijfer, John W M Martens, Saskia M Wilting
Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features. Nature communications 12 (1) (2021)
Florence Atrafi, Oliver Boix, Vivek Subbiah, Jennifer R Diamond, Sant P Chawla, Anthony W Tolcher, Patricia M LoRusso, Joseph P Eder, Martin Gutierrez, Kumar Sankhala, Prabhu Rajagopalan, Isabelle Genvresse, Simon Langer, Ron H J Mathijssen, Jaap Verweij, Ingmar Bruns, Martijn Paul Lolkema
A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (23) (2021)
Lisanne Mout, Jan M Moll, Mingqing Chen, Eleonora S de Morrée, Corrina M A de Ridder, Alice Gibson, Debra Stuurman, Ashraf Aghai, Sigrun Erkens-Schulze, Ron H J Mathijssen, Alex Sparreboom, Ronald de Wit, Martijn Paul Lolkema, Thomas A Kirkland
Androgen receptor signalling impairs docetaxel efficacy in castration-resistant prostate cancer. British journal of cancer 123 (12) (2020)
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, null null, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn Paul Lolkema, Neeltje Steeghs, Gad A Getz, Quaid D Morris, Lincoln D Stein, null null
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature communications 11 (1) (2020)
Oriol Pich, Ferran Muinos, Martijn Paul Lolkema, Neeltje Steeghs, Nuria Lopez-Bigas, Núria López-Bigas
The mutational footprints of cancer therapies. Nature genetics 51 (12) (2019)
Lindsay Angus, Marcel Smid, Saskia M Wilting, Job van Riet, Arne Van Hoeck, Luan Nguyen, Serena Nik-Zainal, Tessa G Steenbruggen, Vivianne C G Tjan-Heijnen, Mariette Labots, Johanna M G H van Riel, Haiko J Bloemendal, Neeltje Steeghs, Martijn Paul Lolkema, Emile E Voest, Harmen J G van de Werken, Agnes Jager, Edwin Cuppen, Stefan Sleijfer, John W M Martens
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies. Nature genetics 51 (10) (2019)
Lisanne F van Dessel, Job van Riet, Minke Smits, Yanyun Zhu, Paul Hamberg, Michiel S van der Heijden, Andries M Bergman, Inge M van Oort, Ronald de Wit, Emile E Voest, Neeltje Steeghs, Takafumi N Yamaguchi, Julie Livingstone, Paul C Boutros, John W M Martens, Stefan Sleijfer, Edwin Cuppen, Wilbert Zwart, Harmen J G van de Werken, Niven Mehra, Martijn Paul Lolkema
The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact. Nature communications 10 (1) (2019)