Serena Nik-Zainal

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 16

Top Venues

Nature communications

Nature genetics

Nature reviews. Cancer

Cancers

University of Cambridge

Wellcome Trust Sanger Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cambridge Sep 01 2017

United Kingdom

CRUK Advanced Clinician Scientist :: MRC Cancer Unit & Department of Medical Genetics

Education History

Wellcome Trust Sanger Institute - Jul 31 2012

United Kingdom

PHD :: Cancer Genome Project

Publications

Shadi Basyuni, Laura Heskin, Andrea Degasperi, Daniella Black, Gene Ching Chiek Koh, Lucia Chmelova, Giuseppe Rinaldi, Steven Bell, Louise Grybowicz, Greg Elgar, Yasin Memari, Pauline Robbe, Zoya Kingsbury, Carlos Caldas, Jean E Abraham, Anna Schuh, Louise Jones, null null, null null, Marc Tischkowitz, Matthew A Brown, Helen R Davies, Serena Nik-Zainal
Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility. Nature communications 15 (1) (2024)
Ha-Linh Nguyen, Tatjana Geukens, Marion Maetens, Samuel A J R Aparicio, Ayse Bassez, Åke Borg, Jane Brock, Annegien Broeks, Carlos Caldas, Fatima Cardoso, Maxim De Schepper, Mauro Delorenzi, Caroline A Drukker, Annuska M Glas, Andrew R Green, Edoardo Isnaldi, Jórunn Eyfjörð, Hazem Khout, Stian Knappskog, Savitri Krishnamurthy, Sunil R Lakhani, Anita Langerod, John W M Martens, Amy E McCart Reed, Leigh Murphy, Stefan Naulaerts, Serena Nik-Zainal, Ines Nevelsteen, Patrick Neven, Martine J Piccart, Coralie Poncet, Kevin Punie, Colin Purdie, Emad A Rakha, Andrea Richardson, Emiel Rutgers, Anne-Vincent Salomon, Peter Thomas Simpson, Marjanka K Schmidt, Christos Sotiriou, Paul N Span, Kiat Tee Benita Tan, Alastair Thompson, Stefania Tommasi, Karen Van Baelen, Marc Van de Vijver, Steven Van Laere, Laura van 't Veer, Giuseppe Viale, Alain Viari, Hanne Vos, Anke T Witteveen, Hans P M W Wildiers, Giuseppe Floris, Abhishek Dinkarnath Garg, Ann Smeets, Diether Lambrechts, Elia Mario Biganzoli, François Richard, Christine Desmedt
Obesity-associated changes in molecular biology of primary breast cancer. Nature communications 14 (1) (2023)
Gene Ching Chiek Koh, Soraya Boushaki, Salome Jingchen Zhao, Andrew Marcel Pregnall, Firas Sadiyah, Cherif Badja, Yasin Memari, Ilias Georgakopoulos-Soares, Serena Nik-Zainal
The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells. Nature genetics (2023)
Sruthi Cheloor Kovilakam, Muxin Gu, William G Dunn, Ludovica Marando, Clea Barcena, Serena Nik-Zainal, Irina I Mohorianu, Siddhartha Kar, Margarete Alice Fabre, Pedro M Quiros, George S Vassiliou
Prevalence and significance of DDX41 gene variants in the general population. Blood (2023)
Erika Durinikova, Nicole M Reilly, Kristi Buzo, Elisa Mariella, Rosaria Chilà, Annalisa Lorenzato, Joao M L Dias, Gaia Grasso, Federica Pisati, Simona Lamba, Giorgio Corti, Andrea Degasperi, Carlotta Cancelliere, Gianluca Mauri, Pietro Andrei, Michael Linnebacher, Silvia Marsoni, Salvatore Siena, Andrea Sartore-Bianchi, Serena Nik-Zainal, Federica Di Nicolantonio, Alberto Bardelli, Sabrina Arena
Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Foad J Rouhani, Xueqing Zou, Petr Danecek, Cherif Badja, Tauanne Dias Amarante, Gene Koh, Qianxin Wu, Yasin Memari, Richard Durbin, Iñigo Martincorena, Andrew R Bassett, Daniel J Gaffney, Serena Nik-Zainal
Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells. Nature genetics 54 (9) (2022)
Esther H Lips, Tapsi Kumar, Anargyros Megalios, Lindy L Visser, Michael Sheinman, Angelo Fortunato, Vandna Shah, Marlous Hoogstraat, Emi Sei, Diego Mallo, Maria Roman-Escorza, Ahmed Abdullah Ahmed, Mingchu Xu, Alexandra W van den Belt-Dusebout, Wim Brugman, Anna K Casasent, Karen Clements, Helen R Davies, Liping Fu, Anita Grigoriadis, Timothy M Hardman, Lorraine M King, Marielle Krete, Petra Kristel, Michiel de Maaker, Carlo C Maley, Jeffrey R Marks, Brian A Menegaz, Lennart Mulder, Frank Nieboer, Salpie Nowinski, Sarah E Pinder, Jelmar Quist, Carolina Salinas-Souza, Michael Schaapveld, Marjanka K Schmidt, Abeer M Shaaban, Rana Shami, Mathini Sridharan, John Zhang, Hilary Stobart, Deborah E Collyar, Serena Nik-Zainal, Lodewyk F A Wessels, E Shelley Hwang, Nicholas E Navin, P Andrew Futreal, null null, Alastair M Thompson, Jelle Wesseling, Elinor J Sawyer
Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer. Nature genetics 54 (6) (2022)
Gene Ching Chiek Koh, Andrea Degasperi, Xueqing Zou, Sophie Momen, Serena Nik-Zainal
Mutational signatures: emerging concepts, caveats and clinical applications. Nature reviews. Cancer 21 (10) (2021)
Helen R Davies, Kevin D Broad, Zerrin Onadim, Elizabeth A Price, Xueqing Zou, Ibrahim Sheriff, Esin Kotiloğlu Karaa, Irene Scheimberg, M Ashwin Reddy, Mandeep S Sagoo, Shin-Ichi Ohnuma, Serena Nik-Zainal
Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature. Cancers 13 (4) (2021)
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers. Nature communications 11 (1) (2020)
Neha Chopra, Holly Tovey, Alex Pearson, Ros Cutts, Christy Toms, Paula Proszek, Michael Hubank, Mitch Dowsett, Andrew Dodson, Frances Daley, Divya Kriplani, Heidi Gevensleben, Helen Ruth Davies, Andrea Degasperi, Rebecca Roylance, Stephen Chan, Andrew Tutt, Anthony Skene, Abigail Evans, Judith M Bliss, Serena Nik-Zainal, Nicholas C Turner
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer. Nature communications 11 (1) (2020)
Oliver Thompson, Ferdinand von Meyenn, Zoe Hewitt, John Alexander, Andrew Wood, Richard Weightman, Sian Gregory, Felix Krueger, Simon Andrews, Ivana Barbaric, Paul J Gokhale, Harry D Moore, Wolf Reik, Marta Milo, Serena Nik-Zainal, Kosuke Yusa, Peter W Andrews
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions. Nature communications 11 (1) (2020)
Ilias Georgakopoulos-Soares, Gene Ching Chiek Koh, Sophie E Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts. Nature communications 11 (1) (2020)
Helen R Davies, Kirsty Hodgson, Edward Schwalbe, Jonathan Coxhead, Naomi Sinclair, Xueqing Zou, Simon Cockell, Akhtar Husain, Serena Nik-Zainal, Neil Rajan
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome. Nature communications 10 (1) (2019)
Lindsay Angus, Marcel Smid, Saskia M Wilting, Job van Riet, Arne Van Hoeck, Luan Nguyen, Serena Nik-Zainal, Tessa G Steenbruggen, Vivianne C G Tjan-Heijnen, Mariette Labots, Johanna M G H van Riel, Haiko J Bloemendal, Neeltje Steeghs, Martijn Paul Lolkema, Emile E Voest, Harmen J G van de Werken, Agnes Jager, Edwin Cuppen, Stefan Sleijfer, John W M Martens
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies. Nature genetics 51 (10) (2019)
Jarno Drost, Ruben van Boxtel, Francis Blokzijl, Tomohiro Mizutani, Nobuo Sasaki, Valentina Sasselli, Joep de Ligt, Sam Behjati, Judith E Grolleman, J Tom van Wezel, Serena Nik-Zainal, Roland P Kuiper, Edwin Cuppen, Hans Clevers
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer. Science (New York, N.Y.) 358 (6360) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Serena Nik-Zainal