Melanie Märklin

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Top Venues

Blood cancer journal

Nature communications

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Samuel J Holzmayer, Joseph Kauer, Jonas Mauermann, Tobias Roider, Melanie Märklin
Asciminib Maintains Antibody-Dependent Cellular Cytotoxicity against Leukemic Blasts. Cancers 16 (7) (2024)
Sylwia Anna Stefańczyk, Clara Hayn, Jonas Heitmann, Susanne Jung, Latifa Zekri, Melanie Märklin
Expression and Prognostic Value of a Novel B7-H3 (CD276) Antibody in Acute Myeloid Leukemia. Cancers 16 (13) (2024)
Sylwia Anna Stefańczyk, Clara Hayn, Jonas Heitmann, Susanne Jung, Latifa Zekri, Melanie Märklin
Expression and Prognostic Value of a Novel B7-H3 (CD276) Antibody in Acute Myeloid Leukemia. Cancers 16 (13) (2024)
Sylwia Anna Stefańczyk, Ilona Hagelstein, Martina S Lutz, Stefanie Müller, Samuel J Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S Heitmann, Helmut R Salih, Melanie Märklin
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody. Blood cancer journal 14 (1) (2024)
Latifa Zekri, Ilona Hagelstein, Melanie Märklin, Boris Klimovich, Mary Christie, Cornelia Lindner, Sofie Kämereit, Nisha Prakash, Stefanie Müller, Sophie Stotz, Andreas Maurer, Carsten L Greve, Bastian Schmied, Daniel Atar, Hans-Georg Rammensee, Gundram Jung, Helmut R Salih
Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies. Science translational medicine 16 (737) (2024)
Sylwia Anna Stefańczyk, Ilona Hagelstein, Martina S Lutz, Stefanie Müller, Samuel J Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S Heitmann, Helmut R Salih, Melanie Märklin
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody. Blood cancer journal 14 (1) (2024)
Anna Seller, Christian Martin Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S Heitmann, Sarah M Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas Daniel Hartkopf, Markus Hahn, Sara Yvonne Brucker, Helmut R Salih, Melanie Märklin
Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome. International journal of molecular sciences 25 (7) (2024)
Sylwia Anna Stefańczyk, Ilona Hagelstein, Martina S Lutz, Stefanie Müller, Samuel J Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S Heitmann, Helmut R Salih, Melanie Märklin
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody. Blood cancer journal 14 (1) (2024)
Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Anita Schmitt, Brigitte Neuber, Daniela Chmiest, Silvia Podavini, Melanie Märklin, Boris Klimovich, Michael Schmitt, Fulya Korkmaz, Claudia Lengerke, Corina Schneidawind, Dominik Schneidawind
PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity. Journal for immunotherapy of cancer 12 (1) (2024)
Sylwia Anna Stefańczyk, Ilona Hagelstein, Martina S Lutz, Stefanie Müller, Samuel J Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S Heitmann, Helmut R Salih, Melanie Märklin
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody. Blood cancer journal 14 (1) (2024)
Anna Seller, Christian Martin Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S Heitmann, Sarah M Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas Daniel Hartkopf, Markus Hahn, Sara Yvonne Brucker, Helmut R Salih, Melanie Märklin
Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome. International journal of molecular sciences 25 (7) (2024)
Sylwia Anna Stefańczyk, Ilona Hagelstein, Martina S Lutz, Stefanie Müller, Samuel J Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S Heitmann, Helmut R Salih, Melanie Märklin
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody. Blood cancer journal 14 (1) (2024)
Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Anita Schmitt, Brigitte Neuber, Daniela Chmiest, Silvia Podavini, Melanie Märklin, Boris Klimovich, Michael Schmitt, Fulya Korkmaz, Claudia Lengerke, Corina Schneidawind, Dominik Schneidawind
PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity. Journal for immunotherapy of cancer 12 (1) (2024)
Samuel J Holzmayer, Joseph Kauer, Jonas Mauermann, Tobias Roider, Melanie Märklin
Asciminib Maintains Antibody-Dependent Cellular Cytotoxicity against Leukemic Blasts. Cancers 16 (7) (2024)
Latifa Zekri, Ilona Hagelstein, Melanie Märklin, Boris Klimovich, Mary Christie, Cornelia Lindner, Sofie Kämereit, Nisha Prakash, Stefanie Müller, Sophie Stotz, Andreas Maurer, Carsten L Greve, Bastian Schmied, Daniel Atar, Hans-Georg Rammensee, Gundram Jung, Helmut R Salih
Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies. Science translational medicine 16 (737) (2024)
Samuel J Holzmayer, Joseph Kauer, Jonas Mauermann, Tobias Roider, Melanie Märklin
Asciminib Maintains Antibody-Dependent Cellular Cytotoxicity against Leukemic Blasts. Cancers 16 (7) (2024)
Latifa Zekri, Ilona Hagelstein, Melanie Märklin, Boris Klimovich, Mary Christie, Cornelia Lindner, Sofie Kämereit, Nisha Prakash, Stefanie Müller, Sophie Stotz, Andreas Maurer, Carsten L Greve, Bastian Schmied, Daniel Atar, Hans-Georg Rammensee, Gundram Jung, Helmut R Salih
Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies. Science translational medicine 16 (737) (2024)
Anna Seller, Christian Martin Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S Heitmann, Sarah M Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas Daniel Hartkopf, Markus Hahn, Sara Yvonne Brucker, Helmut R Salih, Melanie Märklin
Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome. International journal of molecular sciences 25 (7) (2024)
Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Anita Schmitt, Brigitte Neuber, Daniela Chmiest, Silvia Podavini, Melanie Märklin, Boris Klimovich, Michael Schmitt, Fulya Korkmaz, Claudia Lengerke, Corina Schneidawind, Dominik Schneidawind
PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity. Journal for immunotherapy of cancer 12 (1) (2024)
Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Anita Schmitt, Brigitte Neuber, Daniela Chmiest, Silvia Podavini, Melanie Märklin, Boris Klimovich, Michael Schmitt, Fulya Korkmaz, Claudia Lengerke, Corina Schneidawind, Dominik Schneidawind
PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity. Journal for immunotherapy of cancer 12 (1) (2024)
Ashish Goyal, Jens Bauer, Joschka Hey, Dimitris N Papageorgiou, Ekaterina Stepanova, Michael Daskalakis, Jonas Scheid, Marissa L Dubbelaar, Boris Klimovich, Dominic Schwarz, Melanie Märklin, Malte Roerden, Yu-Yu Lin, Tobias Ma, Oliver Mücke, Hans-Georg Rammensee, Michael Lübbert, Fabricio Loayza-Puch, Jeroen Krijgsveld, Juliane Sarah Walz, Christoph Plass
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts. Nature communications 14 (1) (2023)
Polina Kaidun, Samuel J Holzmayer, Sarah M Greiner, Anna Seller, Christian Martin Tegeler, Ilona Hagelstein, Jonas Mauermann, Tobias Engler, André Koch, Andreas Daniel Hartkopf, Helmut R Salih, Melanie Märklin
Targeting NKG2DL with Bispecific NKG2D-CD16 and NKG2D-CD3 Fusion Proteins on Triple-Negative Breast Cancer. International journal of molecular sciences 24 (17) (2023)
Annika Nelde, Heiko Schuster, Jonas S Heitmann, Jens Bauer, Yacine Maringer, Melissa Zwick, Jens-Peter Volkmer, James Y Chen, Anna M Paczulla Stanger, Ariane Lehmann, Bismark Appiah, Melanie Märklin, Elke Rücker-Braun, Helmut R Salih, Malte Roerden, Sarah M Schroeder, Max-Felix Häring, Andreas Schlosser, Johannes Schetelig, Marc Schmitz, Melanie Börries, Natalie Stickel, Claudia Lengerke, Ravindra Majeti, Irving L Weissman, Hans-Georg Rammensee, Juliane Sarah Walz
Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells. Blood cancer discovery (2023)
Jonas S Heitmann, Claudia Tandler, Maddalena Marconato, Annika Nelde, Timorshah Habibzada, Susanne M Rittig, Christian M Tegeler, Yacine Maringer, Simon U Jaeger, Monika Denk, Marion Richter, Melek T Oezbek, Karl-Heinz Wiesmüller, Jens Bauer, Jonas Rieth, Marcel Wacker, Sarah M Schroeder, Naomi Hoenisch Gravel, Jonas Scheid, Melanie Märklin, Annika Henrich, Boris Klimovich, Kim L Clar, Martina Lutz, Samuel Holzmayer, Sebastian Hörber, Andreas Peter, Christoph Meisner, Imma Fischer, Markus W Löffler, Caroline Anna Peuker, Stefan Habringer, Thorsten O Goetze, Elke Jäger, Hans-Georg Rammensee, Helmut R Salih, Juliane Sarah Walz
Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency. Nature communications 14 (1) (2023)
Joseph Kauer, Melanie Märklin, Martin Pflügler, Sebastian Hörner, Clemens Hinterleitner, Claudia Tandler, Gundram Jung, Helmut R Salih, Jonas S Heitmann
BCR::ABL1 tyrosine kinase inhibitors hamper the therapeutic efficacy of blinatumomab in vitro. Journal of cancer research and clinical oncology 148 (10) (2022)
Jenny N H G Ho, Dominik Schmidt, Theresa Lowinus, Jeongmin Ryoo, Elaine-Pashupati Dopfer, Nicolás Gonzalo Núñez, Sara Costa-Pereira, Cristina Toffalori, Marco Punta, Viktor Fetsch, Tobias Wertheimer, Marie-Claire Rittmann, Lukas M Braun, Marie Follo, Christelle Briere, Janaki Manoja Vinnakota, Marlene Langenbach, Felicitas Koppers, Khalid Shoumariyeh, Helena Engel, Tamina Rückert, Melanie Märklin, Samuel Holzmayer, Anna L Illert, Federica Magon, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Julian Staniek, Marta Rizzi, Christoph Cornelius Miething, Natalie Stickel, Justus Duyster, Hans D Menssen, Melanie Börries, Joerg M Buescher, Nina Cabezas-Wallscheid, Bruce R Blazar, Petya Apostolova, Luca Vago, Erika L Pearce, Burkhard Becher, Robert Zeiser
Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140 (10) (2022)
Joseph Kauer, Fabian Vogt, Ilona Hagelstein, Sebastian Hörner, Melanie Märklin, Stefanie Maurer, Helmut R Salih, Gundram Jung, Latifa Zekri
CD18 Antibody Application Blocks Unwanted Off-Target T Cell Activation Caused by Bispecific Antibodies. Cancers 13 (18) (2021)
Malte Roerden, Melanie Märklin, Helmut R Salih, Wolfgang A Bethge, Reinhild Klein, Hans-Georg Rammensee, Annika Nelde, Juliane Sarah Walz
Expression levels of HLA-DR in acute myeloid leukemia: implications for antigenicity and clinical outcome. Leukemia & lymphoma 62 (8) (2021)
Fabian Riegg, Martina S Lutz, Bastian J Schmied, Jonas S Heitmann, Manon Queudeville, Peter Lang, Gundram Jung, Helmut R Salih, Melanie Märklin
An Fc-Optimized CD133 Antibody for Induction of NK Cell Reactivity against B Cell Acute Lymphoblastic Leukemia. Cancers 13 (7) (2021)
Tatjana Bilich, Annika Nelde, Jonas S Heitmann, Yacine Maringer, Malte Roerden, Jens Bauer, Jonas Rieth, Marcel Wacker, Andreas Peter, Sebastian Hörber, David Rachfalski, Melanie Märklin, Stefan Stevanovic, Hans-Georg Rammensee, Helmut R Salih, Juliane Sarah Walz
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals. Science translational medicine 13 (590) (2021)
Kübra Kaban, Clemens Hinterleitner, Yanjun Zhou, Emine Salva, Ayse Gülten Kantarci, Helmut R Salih, Melanie Märklin
Therapeutic Silencing of BCL-2 Using NK Cell-Derived Exosomes as a Novel Therapeutic Approach in Breast Cancer. Cancers 13 (10) (2021)
Kübra Kaban, Sarah M Greiner, Samuel Holzmayer, Claudia Tandler, Sophie Meyer, Clemens Hinterleitner, Helmut R Salih, Melanie Märklin, Jonas S Heitmann
Immunoprofiling of 4-1BB Expression Predicts Outcome in Chronic Lymphocytic Leukemia (CLL). Diagnostics (Basel, Switzerland) 11 (11) (2021)
Matthias Becker, Monika Strengert, Daniel Junker, Philipp D Kaiser, Tobias Kerrinnes, Bjoern Traenkle, Heiko Dinter, Julia Häring, Stéphane Ghozzi, Anne Zeck, Frank Weise, Andreas Peter, Sebastian Hörber, Simon Fink, Felix Ruoff, Alex Dulovic, Tamam Bakchoul, Armin Baillot, Stefan Lohse, Markus Cornberg, Thomas Illig, Jens Gottlieb, Sigrun Smola, André Karch, Klaus Berger, Hans-Georg Rammensee, Katja Schenke-Layland, Annika Nelde, Melanie Märklin, Jonas S Heitmann, Juliane Sarah Walz, Markus Templin, Thomas O Joos, Ulrich Rothbauer, Gérard Krause, Nicole Schneiderhan-Marra
Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity. Nature communications 12 (1) (2021)
Tatjana Bilich, Malte Roerden, Yacine Maringer, Annika Nelde, Jonas S Heitmann, Marissa L Dubbelaar, Andreas Peter, Sebastian Hörber, Jens Bauer, Jonas Rieth, Marcel Wacker, Fiamma Berner, Lukas Flatz, Stefanie Held, Peter Brossart, Melanie Märklin, Philipp Wagner, Eva Erne, Reinhild Klein, Hans-Georg Rammensee, Helmut R Salih, Juliane S Walz
Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer. Cancer discovery 11 (8) (2021)
Jonas S Heitmann, Ilona Hagelstein, Clemens Hinterleitner, Lukas Osburg, Helmut R Salih, Joseph Kauer, Melanie Märklin
Fc gamma receptor expression serves as prognostic and diagnostic factor in AML. Leukemia & lymphoma 61 (10) (2020)
Jonas S Heitmann, Ilona Hagelstein, Clemens Hinterleitner, Malte Roerden, Gundram Jung, Helmut R Salih, Melanie Märklin, Joseph Kauer
Identification of CD318 (CDCP1) as novel prognostic marker in AML. Annals of hematology 99 (3) (2020)
Annika Nelde, Tatjana Bilich, Jonas S Heitmann, Yacine Maringer, Helmut R Salih, Malte Roerden, Maren Lübke, Jens Bauer, Jonas Rieth, Marcel Wacker, Andreas Peter, Sebastian Hörber, Bjoern Traenkle, Philipp D Kaiser, Ulrich Rothbauer, Matthias Becker, Daniel Junker, Gérard Krause, Monika Strengert, Nicole Schneiderhan-Marra, Markus F Templin, Thomas O Joos, Daniel J Kowalewski, Vlatka Stos-Zweifel, Michael Fehr, Armin Rabsteyn, Valbona Mirakaj, Julia Karbach, Elke Jäger, Michael Graf, Lena-Christin Gruber, David Rachfalski, Beate Preuß, Ilona Hagelstein, Melanie Märklin, Tamam Bakchoul, Cécile Gouttefangeas, Oliver Kohlbacher, Reinhild Klein, Stefan Stevanović, Hans-Georg Rammensee, Juliane Sarah Walz
SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition. Nature immunology 22 (1) (2020)
Jonas S Heitmann, Melanie Märklin, Felicia M Truckenmüller, Clemens Hinterleitner, Daniela Dörfel, Michael Haap, Hans-Georg Kopp, Stefan Wirths, Martin R Müller
A novel flow cytometry-based assay to measure compromised B cell receptor signaling as a prognostic factor in chronic lymphocytic leukemia. Journal of leukocyte biology 108 (6) (2020)
Melanie Märklin, Stefanie Bugl, Stefan Wirths, Julia-Stefanie Frick, Martin R Müller, Hans-Georg Kopp, Dominik Schneidawind
Oral intake of lipopolysaccharide regulates toll-like receptor 4-dependent granulopoiesis. Experimental biology and medicine (Maywood, N.J.) 245 (14) (2020)
Melanie Märklin, Claudia Tandler, Hans-Georg Kopp, Kyle L Hoehn, Leticia Quintanilla-Martinez, Oliver Borst, Martin R Müller, Sebastian J Saur
C-Cbl regulates c-MPL receptor trafficking and its internalization. Journal of cellular and molecular medicine 24 (21) (2020)
Tatjana Bilich, Annika Nelde, Leon Bichmann, Malte Roerden, Helmut R Salih, Daniel J Kowalewski, Heiko Schuster, Chih-Chiang Tsou, Ana Marcu, Marian Christoph Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek-Reinders, Tim Henrik Brümmendorf, Vladan Vucinic, Dietger Niederwieser, Jens Bauer, Melanie Märklin, Janet K Peper, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Juliane Sarah Walz
The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy. Blood 133 (6) (2018)
Melanie Märklin, Jonas S Heitmann, Alexander R Fuchs, Felicia M Truckenmüller, Michael Gutknecht, Stefanie Bugl, Sebastian J Saur, Juliane Lazarus, Ursula Kohlhofer, Leticia Quintanilla-Fend, Hans-Georg Rammensee, Helmut R Salih, Hans-Georg Kopp, Michael Haap, Andreas Kirschniak, Lothar Kanz, Anjana Rao, Stefan Wirths, Martin R Müller
NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia. Nature communications 8 (1) (2017)