Methvin B Isaac

Publication Activity (10 Years)

Years Active: 2023-2024
Publications (10 Years): 17

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Advanced Non Small Cell Lung Cancer

Epidermal Growth Factor Receptor

Top Venues

Journal of medicinal chemistry

Cancer research

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer research (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer research (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Ahmed Mamai, Anh M Chau, Brian J Wilson, Iain D Watson, Babu B Joseph, Pandiaraju R Subramanian, Monzur M Morshed, Justin A Morin, Michael A Prakesch, Tianbao Lu, Pete Connolly, Douglas A Kuntz, Neil C Pomroy, Gennady Poda, Kong Nguyen, Richard Marcellus, Graig Strathdee, Brigitte Theriault, Ratheesh Subramaniam, Mohammed Mohammed, Ayome Abibi, Manuel Chan, Jeffrey Winston, Taira Kiyota, Elijus Undzys, Ahmed M Aman, Nigel Austin, Marc Du Jardin, Kathryn Packman, Ulrike Phillippar, Riccardo Attar, James Edwards, Jeff O'Meara, David E Uehling, Rima Al-Awar, Gilbert G Privé, Methvin B Isaac
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS medicinal chemistry letters 14 (2) (2023)
Ahmed Mamai, Anh M Chau, Brian J Wilson, Iain D Watson, Babu B Joseph, Pandiaraju R Subramanian, Monzur M Morshed, Justin A Morin, Michael A Prakesch, Tianbao Lu, Pete Connolly, Douglas A Kuntz, Neil C Pomroy, Gennady Poda, Kong Nguyen, Richard Marcellus, Graig Strathdee, Brigitte Theriault, Ratheesh Subramaniam, Mohammed Mohammed, Ayome Abibi, Manuel Chan, Jeffrey Winston, Taira Kiyota, Elijus Undzys, Ahmed M Aman, Nigel Austin, Marc Du Jardin, Kathryn Packman, Ulrike Phillippar, Riccardo Attar, James Edwards, Jeff O'Meara, David E Uehling, Rima Al-Awar, Gilbert G Privé, Methvin B Isaac
Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS medicinal chemistry letters 14 (2) (2023)