Rima Al-Awar

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 16

Top Topics

Acute Myeloid Leukemia

Tyrosine Kinase

Multiple Myeloma

Helicobacter Pylori

Top Venues

Journal of medicinal chemistry

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer research (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer research (2024)
Yongwei Su, Jenna L Carter, Xinyu Li, Yu Fukuda, Ashley Gray, John Lynch, Holly Edwards, Jun Ma, Patrick A Schreiner, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Steven A Buck, Shondra M Pruett-Miller, Katie Hege Hurrish, Camenzind G Robinson, Xinan Qiao, Shuang Liu, Shuangshuang Wu, Guan Wang, Jing Li, Joshua E Allen, Varun V Prabhu, Aaron David Schimmer, Dhananjay Joshi, Shiva Kalhor-Monfared, Iain D G Watson, Richard Marcellus, Methvin B Isaac, Rima Al-Awar, Jeffrey W Taub, Hai Lin, John D Schuetz, Yubin Ge
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Mandeep K Mann, Carlos A Zepeda-Velázquez, Héctor González-Álvarez, Aiping Dong, Taira Kiyota, Ahmed M Aman, Peter Loppnau, Yanjun Li, Brian Wilson, Cheryl H Arrowsmith, Rima Al-Awar, Rachel J Harding, Matthieu Schapira
Structure-Activity Relationship of USP5 Inhibitors. Journal of medicinal chemistry 64 (20) (2021)
David E Uehling, Babu Joseph, Kim Chan Chung, Andrew X Zhang, Spencer Ler, Michael A Prakesch, Gennady Poda, Julie Grouleff, Ahmed M Aman, Taira Kiyota, Chungyee Leung-Hagesteijn, John David Konda, Richard Marcellus, Carly Griffin, Ratheesh Subramaniam, Ayome Abibi, Craig A Strathdee, Methvin B Isaac, Rima Al-Awar, Rodger E Tiedemann
Correction to "Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma". Journal of medicinal chemistry 65 (1) (2021)
David E Uehling, Babu Joseph, Kim Chan Chung, Andrew X Zhang, Spencer Ler, Michael A Prakesch, Gennady Poda, Julie Grouleff, Ahmed Aman, Taira Kiyota, Chungyee Leung-Hagesteijn, John David Konda, Richard Marcellus, Carly Griffin, Ratheesh Subramaniam, Ayome Abibi, Craig A Strathdee, Methvin B Isaac, Rima Al-Awar, Rodger E Tiedemann
Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma. Journal of medicinal chemistry 64 (15) (2021)
Mandeep K Mann, Carlos A Zepeda-Velázquez, Héctor González-Álvarez, Aiping Dong, Taira Kiyota, Ahmed M Aman, Peter Loppnau, Yanjun Li, Brian Wilson, Cheryl H Arrowsmith, Rima Al-Awar, Rachel J Harding, Matthieu Schapira
Correction to "Structure-Activity Relationship of USP5 Inhibitors". Journal of medicinal chemistry 65 (1) (2021)
Deeba Ensan, David Smil, Carlos A Zepeda-Velázquez, Dimitrios Panagopoulos, Jong Fu Wong, Eleanor P Williams, Roslin Adamson, Alex N Bullock, Taira Kiyota, Ahmed Aman, Owen G Roberts, Aled M Edwards, Jeff A O'Meara, Methvin B Isaac, Rima Al-Awar
Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. Journal of medicinal chemistry 63 (9) (2020)
David Smil, Jong Fu Wong, Eleanor P Williams, Roslin J Adamson, Alison Howarth, David A McLeod, Ahmed Mamai, Soyoung Kim, Brian J Wilson, Taira Kiyota, Ahmed Aman, Julie Owen, Gennady Poda, Kurumi Y Horiuchi, Ekaterina Kuznetsova, Haiching Ma, J Nicole Hamblin, Sue Cramp, Owen G Roberts, Aled Morgan Edwards, David Uehling, Rima Al-Awar, Alex N Bullock, Jeff A O'Meara, Methvin B Isaac
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. Journal of medicinal chemistry 63 (17) (2020)