Alex N Bullock (Alex Bullock)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 57

Top Venues

ACS chemical neuroscience

Journal of medicinal chemistry

Journal of medical genetics

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics 61 (5) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience 15 (7) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics 61 (5) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience 15 (7) (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience 15 (7) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics 61 (5) (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics 61 (5) (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience 15 (7) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot Singh Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. bioRxiv : the preprint server for biology (2024)
Lieve van Veggel, Tamara A M Mocking, Hubert J Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A Dilweg, Jeroen Royakkers, Anna Li, Vijay Kumar, Yin Yao Dong, Alex N Bullock, David B Sauer, Hanne Diliën, Gerard van Westen, Rudy Schreiber, Laura H Heitman, Tim Vanmierlo
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. ACS chemical neuroscience 15 (7) (2024)
Kerry A Miller, David A Cruz Walma, Daniel M Pinkas, Rebecca S Tooze, Joshua C Bufton, William Richardson, Charlotte E Manning, Alice E Hunt, Julien Cros, Verity Hartill, Michael J Parker, Simon J McGowan, Stephen R F Twigg, Rod Chalk, David Staunton, David Johnson, Andrew O M Wilkie, Alex N Bullock
BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome. Journal of medical genetics 61 (5) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Václav Němec, Marek Remeš, Petr Beňovský, Michael C Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilmann Berger, Carrow I Wells, Cesear R Corona, James D Vasta, Matthew B Robers, Pavel Krejci, Karel Souček, Alex N Bullock, Stefan Knapp, Kamil Paruch
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Journal of medicinal chemistry 67 (15) (2024)
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, Gabriel Morel, Josie A Silvaroli, Carrow I Wells, Bruce A Bunnell, David Harold Drewry, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, Alison D Axtman
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2. ACS medicinal chemistry letters 15 (8) (2024)
Héctor González-Álvarez, Deeba Ensan, Tao Xin, Jong Fu Wong, Carlos A Zepeda-Velázquez, Julien Cros, Melissa N Sweeney, Laurent Hoffer, Taira Kiyota, Brian J Wilson, Ahmed M Aman, Owen Roberts, Methvin B Isaac, Alex N Bullock, David Smil, Rima Al-Awar
Discovery of Conformationally Constrained ALK2 Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex N Bullock, Ulrich A K Betz, Jark Böttcher, Peter J Brown, Menorca Chaturvedi, Alisa Crisp, Danette L Daniels, Jan Dreher, Kristina Edfeldt, Aled Morgan Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V Hartung, Alexander Hillisch, Evert J Homan, Stefan Knapp, Markus Köster, Oliver Krämer, Josep Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H Todd, Claudia Tredup, Jennifer Venable, Timothy M Willson, Cheryl H Arrowsmith
Target 2035 - an update on private sector contributions. RSC medicinal chemistry 14 (6) (2023)
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex N Bullock, Ulrich A K Betz, Jark Böttcher, Peter J Brown, Menorca Chaturvedi, Alisa Crisp, Danette L Daniels, Jan Dreher, Kristina Edfeldt, Aled Morgan Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V Hartung, Alexander Hillisch, Evert J Homan, Stefan Knapp, Markus Köster, Oliver Krämer, Josep Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H Todd, Claudia Tredup, Jennifer Venable, Timothy M Willson, Cheryl H Arrowsmith
Target 2035 - an update on private sector contributions. RSC medicinal chemistry 14 (6) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience 14 (9) (2023)
Han Wee Ong, Yi Liang, William Richardson, Emily R Lowry, Carrow I Wells, Xiangrong Chen, Margaux Silvestre, Kelvin Dempster, Josie A Silvaroli, Jeffery L Smith, Hynek Wichterle, Navjot S Pabla, Sila K Ultanir, Alex N Bullock, David Harold Drewry, Alison D Axtman
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS chemical neuroscience (2023)
Zhuoyao Chen, Rafael M Ioris, Stacey Richardson, Ava N Van Ess, Iolanda Vendrell, Benedikt Mathias Kessler, Francesca M Buffa, Luca Busino, Steven C Clifford, Alex N Bullock, Vincenzo D'Angiolella
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation. Cell death and differentiation 29 (10) (2022)
David Alexandre Cruz Walma, Zhuoyao Chen, Alex N Bullock, Kenneth M Yamada
Ubiquitin ligases: guardians of mammalian development. Nature reviews. Molecular cell biology 23 (5) (2022)
Zhuoyao Chen, Jinwei Zhang, Adrián R Murillo-de-Ozores, María Castañeda-Bueno, Francesca D'Amico, Raphael Heilig, Charlotte E Manning, Fiona J Sorrell, Vincenzo D'Angiolella, Roman Fischer, Monique P C Mulder, Gerardo Gamba, Dario R Alessi, Alex N Bullock
Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase. The Biochemical journal 479 (5) (2022)
Francesc Ventura Pujol, Eleanor P Williams, Makoto Ikeya, Alex N Bullock, Peter Ten Dijke, Marie-José T H Goumans, Gonzalo Sanchez-Duffhues
Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva. Biomedicines 9 (2) (2021)
Eleanor P Williams, Elise Riesebos, Georgina Kerr, Alex N Bullock
ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex. Biomedicines 9 (2) (2021)
Olivier Etebe Nonga, Darja Lavogina, Erki Enkvist, Katrin Kestav, Apirat Chaikuad, Sarah E Dixon-Clarke, Alex N Bullock, Sergei Kopanchuk, Taavi Ivan, Ramesh Ekambaram, Kaido Viht, Stefan Knapp, Asko Uri
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules (Basel, Switzerland) 26 (14) (2021)
Sandra Röhm, Benedict-Tilmann Berger, Martin Schröder, Deep Chatterjee, Sebastian Mathea, Andreas C Joerger, Daniel M Pinkas, Joshua C Bufton, Amelie Tjaden, Lohitesh Kovooru, Mark Kudolo, Christian Pohl, Alex N Bullock, Susanne Müller, Stefan A Laufer, Stefan Knapp
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. Journal of medicinal chemistry 64 (18) (2021)
Martin Schröder, Alex N Bullock, Oleg Fedorov, Franz Bracher, Apirat Chaikuad, Stefan Knapp
DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. Journal of medicinal chemistry 63 (18) (2020)
David Smil, Jong Fu Wong, Eleanor P Williams, Roslin J Adamson, Alison Howarth, David A McLeod, Ahmed Mamai, Soyoung Kim, Brian J Wilson, Taira Kiyota, Ahmed Aman, Julie Owen, Gennady Poda, Kurumi Y Horiuchi, Ekaterina Kuznetsova, Haiching Ma, J Nicole Hamblin, Sue Cramp, Owen G Roberts, Aled Morgan Edwards, David Uehling, Rima Al-Awar, Alex N Bullock, Jeff A O'Meara, Methvin B Isaac
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. Journal of medicinal chemistry 63 (17) (2020)
Diana Carvalho, Kathryn R Taylor, Nagore Gene Olaciregui, Valeria Molinari, Matthew Clarke, Alan Mackay, Ruth Ruddle, Alan Henley, Melanie Valenti, Angela Hayes, Alexis De Haven Brandon, Suzanne A Eccles, Florence Raynaud, Aicha Boudhar, Michelle Monje, Sergey Popov, Andrew S Moore, Jaume Mora, Ofelia Cruz Martinez, Mara Vinci, Paul E Brennan, Alex N Bullock, Angel Montero Carcaboso, Chris Jones
ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma. Communications biology 2 (2019)
Gonzalo Sánchez-Duffhues, Eleanor Williams, Pascal Benderitter, Valeria V Orlova, Michiel van Wijhe, Amaya Garcia de Vinuesa, Georgina Kerr, Josselin Caradec, Kirsten Lodder, Hetty C de Boer, Marie-José Goumans, Elisabeth M W Eekhoff, Antonio Morales-Piga, Javier Bachiller-Corral, Pieter Koolwijk, Alex N Bullock, Jan Hoflack, Peter Ten Dijke
Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells. JBMR plus 3 (11) (2019)
Matthieu Schapira, Matthew F Calabrese, Alex N Bullock, Craig M Crews
Targeted protein degradation: expanding the toolbox. Nature reviews. Drug discovery 18 (12) (2019)
Luke J Fulcher, Polyxeni Bozatzi, Theresa Tachie-Menson, Kevin Z L Wu, Timothy D Cummins, Joshua C Bufton, Daniel M Pinkas, Karen J Dunbar, Sabin Shrestha, Nicola T Wood, Simone Weidlich, Thomas J Macartney, Joby Varghese, Robert Gourlay, David G Campbell, Kevin S Dingwell, James C Smith, Alex N Bullock, Gopal P Sapkota
The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms. Science signaling 11 (531) (2018)
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Eva Maria Putz, Kimberley Stannard, Jian-Guo Zhang, Charis Teh, Matt Firth, Takashi Ushiki, Christopher E Andoniou, Mariapia A Degli-Esposti, Phillip P Sharp, Caroline E Sanvitale, Giuseppe Infusini, Nicholas P D Liau, Edmond M Linossi, Christopher J Burns, Sebastian Carotta, Daniel H D Gray, Cyril Seillet, Dana S Hutchinson, Gabrielle T Belz, Andrew I Webb, Warren S Alexander, Shawn S Li, Alex N Bullock, Jeffrey J Babon, Mark J Smyth, Sandra E Nicholson, Nicholas D Huntington
CIS is a potent checkpoint in NK cell-mediated tumor immunity. Nature immunology 17 (7) (2016)
Tinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, Sarah E Dixon-Clarke, Brian J Abraham, Ann K Greifenberg, Scott B Ficarro, Jonathan M Elkins, Yanke Liang, Nancy M Hannett, Theresa Manz, Mingfeng Hao, Bartlomiej Bartkowiak, Arno L Greenleaf, Jarrod A Marto, Matthias Geyer, Alex N Bullock, Richard A Young, Nathanael S Gray
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature chemical biology 12 (10) (2016)

Alex N Bullock (Alex Bullock)

Publication Activity (10 Years)

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